Lista de obras - Robbie Loewith - Dominio Público Uruguay

A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction

artículo científico publicado en 2016

A brief history of TOR ⬇️

artículo científico publicado el 1 de abril de 2011

A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast

artículo científico publicado en 2014

A pathway of targeted autophagy is induced by DNA damage in budding yeast

artículo científico publicado en 2017

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

artículo científico publicado en 2006

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

artículo científico publicado en 2009

Amino Acid Signaling in High Definition

scholarly article by Christl Gaubitz published in December 2012

Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response

artículo científico publicado en 2009

Caffeine extends yeast lifespan by targeting TORC1.

artículo científico publicado en 2008

Cell growth control: little eukaryotes make big contributions.

artículo científico publicado en 2006

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

artículo científico publicado en 2009

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9

artículo científico publicado en 2020

Chemical biology approaches to membrane homeostasis and function

artículo científico publicado en 2011

Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2

artículo científico publicado en 2018

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

artículo científico publicado en 2016

Dynamic metabolome profiling uncovers potential TOR signaling genes

artículo científico publicado en 2023

Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology

artículo científico publicado en 2009

Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

artículo científico publicado en 2004

Growth control: function follows form

artículo científico publicado en 2013

Human ING1 proteins differentially regulate histone acetylation

artículo científico publicado en 2002

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

artículo científico publicado en 2012

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

artículo científico publicado en 2004

Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae.

artículo científico publicado en 2011

Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.

artículo científico publicado en 2015

Molecular organization of target of rapamycin complex 2.

artículo científico publicado en 2005

Mutual antagonism of target of rapamycin and calcineurin signaling

artículo científico

Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae

artículo científico publicado en 2001

Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast

artículo científico publicado en 2010

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.

artículo científico publicado en 2012

Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation

artículo científico publicado en 2016

Roles for PI(3,5)P2 in nutrient sensing through TORC1.

artículo científico publicado en 2014

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

artículo científico publicado en 2007

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L.

artículo científico publicado en 2011

Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling

artículo científico publicado en 2009

Skh1, the MEK component of the mkh1 signaling pathway in Schizosaccharomyces pombe

artículo científico publicado en 2000

Structural Insights into TOR Signaling

scientific article published on 04 August 2020

Systematic analysis of complex genetic interactions.

artículo científico publicado en 2018

Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

artículo científico publicado en 2014

TOR Complexes and the Maintenance of Cellular Homeostasis

artículo científico publicado en 2015

TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast

artículo científico publicado en 2020

TOR signaling in growth and metabolism

artículo científico publicado en 2006

TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae

artículo científico publicado en 2016

TORC2 Structure and Function

artículo científico publicado en 2016

TORC2 controls endocytosis through plasma membrane tension

artículo científico publicado en 2019

TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.

artículo científico publicado en 2013

Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways

artículo científico publicado en 2015

Target of rapamycin (TOR) in nutrient signaling and growth control

artículo científico publicado en 2011

Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae

artículo científico publicado en 2018

Tensing Up for Lipid Droplet Formation

artículo científico publicado en 2017

The TOR signalling network from yeast to man.

artículo científico publicado en 2006

The Vam6 GEF controls TORC1 by activating the EGO complex

artículo científico publicado en 2009

The flipside of the TOR coin - TORC2 and plasma membrane homeostasis at a glance

scientific article published on 11 May 2020

Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

artículo científico publicado en 2000

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

artículo científico publicado en 2005

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

artículo científico publicado en 2002

Lista de obras de Robbie Loewith

A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction

A brief history of TOR ⬇️

A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeast

A pathway of targeted autophagy is induced by DNA damage in budding yeast

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Amino Acid Signaling in High Definition

Arsenic toxicity to Saccharomyces cerevisiae is a consequence of inhibition of the TORC1 kinase combined with a chronic stress response

Caffeine extends yeast lifespan by targeting TORC1.

Cell growth control: little eukaryotes make big contributions.

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9

Chemical biology approaches to membrane homeostasis and function

Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

Dynamic metabolome profiling uncovers potential TOR signaling genes

Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology

Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

Growth control: function follows form

Human ING1 proteins differentially regulate histone acetylation

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Mitochondrial genomic dysfunction causes dephosphorylation of Sch9 in the yeast Saccharomyces cerevisiae.

Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.

Molecular organization of target of rapamycin complex 2.

Mutual antagonism of target of rapamycin and calcineurin signaling

Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae

Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.

Reciprocal Regulation of Target of Rapamycin Complex 1 and Potassium Accumulation

Roles for PI(3,5)P2 in nutrient sensing through TORC1.

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L.

Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling

Skh1, the MEK component of the mkh1 signaling pathway in Schizosaccharomyces pombe

Structural Insights into TOR Signaling

Systematic analysis of complex genetic interactions.

Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

TOR Complexes and the Maintenance of Cellular Homeostasis

TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast

TOR signaling in growth and metabolism

TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae

TORC2 Structure and Function

TORC2 controls endocytosis through plasma membrane tension

TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.

Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways

Target of rapamycin (TOR) in nutrient signaling and growth control

Target of rapamycin complex 2-dependent phosphorylation of the coat protein Pan1 by Akl1 controls endocytosis dynamics in Saccharomyces cerevisiae

Tensing Up for Lipid Droplet Formation

The TOR signalling network from yeast to man.

The Vam6 GEF controls TORC1 by activating the EGO complex

The flipside of the TOR coin - TORC2 and plasma membrane homeostasis at a glance

Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control