Lista de obras - David Warburton - Dominio Público Uruguay

A Grhl2-dependent gene network controls trophoblast branching morphogenesis

artículo científico publicado en 2015

A Modified Technique for Partial Pneumonectomy in the Mouse ⬇️

artículo científico publicado el 1 de enero de 2011

A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis

artículo científico publicado en 2005

A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells

artículo científico publicado en 2015

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma

artículo científico publicado en 2009

Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema

artículo científico publicado en 2004

Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling

artículo científico publicado en 2013

Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation

artículo científico publicado en 2012

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation

Amniotic Fluid Stem Cells Inhibit the Progression of Bleomycin-Induced Pulmonary Fibrosis via CCL2 Modulation in Bronchoalveolar Lavage ⬇️

artículo científico publicado el 13 de agosto de 2013

BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction

artículo científico publicado en 2006

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

scientific journal article

Burkholderia cepacia-induced IL-8 gene expression in an alveolar epithelial cell line: signaling through CD14 and mitogen-activated protein kinase

artículo científico publicado en 2003

Cartilage rings contribute to the proper embryonic tracheal epithelial differentiation, metabolism, and expression of inflammatory genes

artículo científico publicado en 2016

Cell-based therapies for lung disease ⬇️

artículo científico publicado el 25 de enero de 2012

Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice ⬇️

artículo científico publicado el 8 de julio de 2011

Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway

artículo científico publicado en 2005

Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair.

artículo científico publicado en 2011

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung

artículo científico publicado en 2005

Differential epithelial growth in tissue-engineered larynx and trachea generated from postnatal and fetal progenitor cells

scientific article published on 25 January 2019

Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung

artículo científico publicado en 2006

Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse

Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-alpha

artículo científico publicado en 2008

Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner.

artículo científico publicado en 2012

Entrained pulmonary clocks: epithelium and vasculature keeping pace ⬇️

artículo científico publicado el 6 de agosto de 2010

Epicardial Epithelial-to-Mesenchymal Transition in Heart Development and Disease

artículo científico publicado en 2016

Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation

artículo científico publicado en 2010

Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium ⬇️

artículo científico publicado el 1 de abril de 2011

Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium ⬇️

artículo científico publicado el 8 de junio de 2012

Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung ⬇️

artículo científico publicado el 1 de febrero de 2011

FGF10 controls the patterning of the tracheal cartilage rings via Shh ⬇️

artículo científico publicado el 9 de diciembre de 2010

FGF9-Pitx2-FGF10 signaling controls cecal formation in mice.

artículo científico publicado en 2012

Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

artículo científico publicado en 2020

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

scientific journal article

Fibroblast growth factor 10 (Fgf10) invalidation results in anorectal malformation in mice

scientific journal article

Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development

scientific journal article

Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome

artículo científico publicado en 2009

Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia

artículo científico publicado en 2004

Fibroblast growth factor-10 serves a regulatory role in duodenal development

artículo científico publicado en 2005

Functional analysis of the human Sprouty2 gene promoter

artículo científico publicado en 2003

Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis

artículo científico publicado en 2004

Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.

scientific article published on 27 December 2013

Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry

artículo científico publicado en 2003

Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications.

artículo científico

Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages

artículo científico publicado en 2008

Human lung branching morphogenesis is orchestrated by the spatio-temporal distribution of ACTA2, SOX2 and SOX9.

artículo científico publicado en 2017

Impact of Seasonal Winter Air Pollution on Health across the Lifespan in Mongolia and Some Putative Solutions.

artículo científico publicado en 2018

Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization

artículo científico publicado en 2016

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis

artículo científico publicado en 2015

Infection-induced kinin B1 receptors in human pulmonary fibroblasts: role of intact pathogens and p38 mitogen-activated protein kinase-dependent signaling

artículo científico publicado en 2005

Inhaled resveratrol treatments slow ageing-related degenerative changes in mouse lung

artículo científico publicado en 2017

Injection of amniotic fluid stem cells delays progression of renal fibrosis.

artículo científico publicado en 2012

Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung

scientific article published on 03 July 2019

Isolation and Characterization of Distal Lung Progenitor Cells ⬇️

artículo científico publicado el 1 de enero de 2012

Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells

artículo científico publicado en 2003

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

scientific journal article

Lo, and the niche is knit: lysyl oxidase activity and maintenance of lung, aorta, and skin integrity

artículo científico

Lung development and adult lung diseases

artículo científico publicado en 2007

Lung development and susceptibility to chronic obstructive pulmonary disease

artículo científico publicado en 2006

Lung mesenchymal expression of Sox9 plays a critical role in tracheal development.

artículo científico publicado en 2013

Lung organogenesis

artículo científico publicado en 2010

LungMAP: The Molecular Atlas of Lung Development Program.

artículo científico

MIR-99a and MIR-99b Modulate TGF-β Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells ⬇️

artículo científico publicado el 27 de enero de 2012

Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha

artículo científico publicado en 2009

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

artículo científico publicado en 2015

Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice ⬇️

artículo científico publicado el 17 de mayo de 2011

Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia

scientific article published on 25 April 2019

Modulating the Alveolar Milieu to Enhance Resolution of Fibrotic Lung Injury ⬇️

artículo científico publicado el 1 de julio de 2012

Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice ⬇️

artículo científico publicado el 18 de mayo de 2012

Molecular mechanisms of early lung specification and branching morphogenesis

artículo científico publicado en 2005

Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung

artículo científico publicado en 2015

Morphogenetic implications of peristaltic fluid-tissue dynamics in the embryonic lung

artículo científico publicado en 2015

Murine nitrofen-induced pulmonary hypoplasia does not involve induction of TGF-beta signaling

artículo científico publicado en 2002

Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse

artículo científico publicado en 2002

Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins

artículo científico publicado en 2004

Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.

artículo científico publicado en 2009

Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response ⬇️

artículo científico publicado el 1 de abril de 2011

Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation

artículo científico publicado en 2008

Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3

artículo científico publicado en 2007

Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis

artículo científico publicado en 2010

Quantifying cellular and subcellular stretches in embryonic lung epithelia under peristalsis: where to look for mechanosensing

artículo científico publicado en 2016

Quantifying stretch and secretion in the embryonic lung: Implications for morphogenesis.

artículo científico

Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR.

artículo científico publicado en 2008

Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479.

artículo científico publicado en 2017

Retraction: Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J. Cell. Sci. doi: 10.1242/102848.

artículo científico publicado en 2017

Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung ⬇️

artículo científico publicado el 6 de marzo de 2011

Smad1 expression and function during mouse embryonic lung branching morphogenesis

artículo científico publicado en 2005

Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

artículo científico publicado en 2002

Smad3 signaling involved in pulmonary fibrosis and emphysema

artículo científico publicado en 2006

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development.

artículo científico publicado en 2018

Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer

artículo científico publicado en 2013

Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells

artículo científico publicado en 2007

Stem cells and cell therapies in lung biology and lung diseases

scientific article published on 01 June 2011

Stem/progenitor cells in lung development, injury repair, and regeneration

artículo científico publicado en 2008

Stem/progenitor cells in lung morphogenesis, repair, and regeneration

artículo científico publicado en 2004

Strain-induced Differentiation of Fetal Type II Epithelial Cells Is Mediated via the Integrin α6β1-ADAM17/Tumor Necrosis Factor-α-converting Enzyme (TACE) Signaling Pathway ⬇️

artículo científico publicado el 25 de julio de 2013

TACE is required for fetal murine cardiac development and modeling ⬇️

artículo científico publicado el 15 de septiembre de 2003

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

scientific journal article

TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development? ⬇️

artículo científico publicado el 16 de noviembre de 2012

TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells

artículo científico publicado en 2007

The Transcription Factors Grainyhead-like 2 and NK2-Homeobox 1 Form a Regulatory Loop That Coordinates Lung Epithelial Cell Morphogenesis and Differentiation ⬇️

artículo científico publicado el 6 de septiembre de 2012

The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

artículo científico publicado en 2007

The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR.

artículo científico publicado en 2016

The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia

artículo científico publicado en 2006

The human gamma-glutamyltransferase gene family

artículo científico publicado en 2008

The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors

artículo científico publicado en 2011

The molecular genetics of lung morphogenesis and injury repair

artículo científico publicado en 2004

Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway

artículo científico publicado en 2007

Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia

artículo científico publicado en 2003

Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs

artículo científico publicado en 2010

VEGF Optimizes the Formation of Tissue-Engineered Small Intestine ⬇️

artículo científico publicado el 1 de septiembre de 2011

VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis

scientific journal article

miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution

artículo científico publicado en 2009

Lista de obras de David Warburton

A Grhl2-dependent gene network controls trophoblast branching morphogenesis

A Modified Technique for Partial Pneumonectomy in the Mouse ⬇️

A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis

A novel profibrotic mechanism mediated by TGFβ-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma

Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema

Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling

Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation

Amniotic Fluid Stem Cells Inhibit the Progression of Bleomycin-Induced Pulmonary Fibrosis via CCL2 Modulation in Bronchoalveolar Lavage ⬇️

BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction

Bcr and Abr cooperate in negatively regulating acute inflammatory responses

Burkholderia cepacia-induced IL-8 gene expression in an alveolar epithelial cell line: signaling through CD14 and mitogen-activated protein kinase

Cartilage rings contribute to the proper embryonic tracheal epithelial differentiation, metabolism, and expression of inflammatory genes

Cell-based therapies for lung disease ⬇️

Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis inSmad3knockout mice ⬇️

Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway

Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair.

Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung

Differential epithelial growth in tissue-engineered larynx and trachea generated from postnatal and fetal progenitor cells

Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung

Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse

Down-regulation of Sprouty2 via p38 MAPK plays a key role in the induction of cellular apoptosis by tumor necrosis factor-alpha

Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner.

Entrained pulmonary clocks: epithelium and vasculature keeping pace ⬇️

Epicardial Epithelial-to-Mesenchymal Transition in Heart Development and Disease

Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation

Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium ⬇️

Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium ⬇️

Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung ⬇️

FGF10 controls the patterning of the tracheal cartilage rings via Shh ⬇️

FGF9-Pitx2-FGF10 signaling controls cecal formation in mice.

Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

Fibroblast growth factor 10 (Fgf10) invalidation results in anorectal malformation in mice

Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development

Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome

Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia

Fibroblast growth factor-10 serves a regulatory role in duodenal development

Functional analysis of the human Sprouty2 gene promoter

Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis

Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.

Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry

Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications.

Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages

Human lung branching morphogenesis is orchestrated by the spatio-temporal distribution of ACTA2, SOX2 and SOX9.

Impact of Seasonal Winter Air Pollution on Health across the Lifespan in Mongolia and Some Putative Solutions.

Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis

Infection-induced kinin B1 receptors in human pulmonary fibroblasts: role of intact pathogens and p38 mitogen-activated protein kinase-dependent signaling

Inhaled resveratrol treatments slow ageing-related degenerative changes in mouse lung

Injection of amniotic fluid stem cells delays progression of renal fibrosis.

Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung

Isolation and Characterization of Distal Lung Progenitor Cells ⬇️

Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

Lo, and the niche is knit: lysyl oxidase activity and maintenance of lung, aorta, and skin integrity

Lung development and adult lung diseases

Lung development and susceptibility to chronic obstructive pulmonary disease

Lung mesenchymal expression of Sox9 plays a critical role in tracheal development.

Lung organogenesis

LungMAP: The Molecular Atlas of Lung Development Program.

MIR-99a and MIR-99b Modulate TGF-β Induced Epithelial to Mesenchymal Plasticity in Normal Murine Mammary Gland Cells ⬇️

Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice ⬇️

Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia

Modulating the Alveolar Milieu to Enhance Resolution of Fibrotic Lung Injury ⬇️

Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice ⬇️

Molecular mechanisms of early lung specification and branching morphogenesis

Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung

Morphogenetic implications of peristaltic fluid-tissue dynamics in the embryonic lung

Murine nitrofen-induced pulmonary hypoplasia does not involve induction of TGF-beta signaling

Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse

Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins

Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.

Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response ⬇️

Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation

Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3