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Lista de obras de Albert Jeltsch

A Continuous Protein Methyltransferase (G9a) Assay for Enzyme Activity Measurement and Inhibitor Screening

artículo científico publicado en 2009

A Fast and Accurate Enzyme-Linked Immunosorbent Assay for the Determination of the DNA Cleavage Activity of Restriction Endonucleases

artículo científico publicado en 1993

A Fluorescence-Based Supramolecular Tandem Assay for Monitoring Lysine Methyltransferase Activity in Homogeneous Solution

artículo científico publicado en 2012

A dodecapeptide comprising the extended chain-alpha 4 region of the restriction endonuclease EcoRI specifically binds to the EcoRI recognition site

artículo científico

A fluorimetric assay for on-line detection of DNA cleavage by restriction endonucleases

artículo científico publicado en 2002

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

artículo científico publicado en 2003

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase

artículo científico publicado en 2006

Activity and specificity of the human SUV39H2 protein lysine methyltransferase

scientific article published on 22 November 2014

Affinity reagents for studying histone modifications & guidelines for their quality control

artículo científico publicado en 2015

Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm

artículo científico publicado en 2016

An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric heterochromatin

artículo científico publicado en 2015

Analysis of the Substrate Specificity of the SMYD2 Protein Lysine Methyltransferase and Discovery of Novel Non-Histone Substrates

scientific article published on 29 October 2019

Analysis of the substrate specificity of the Dim-5 histone lysine methyltransferase using peptide arrays

artículo científico publicado en 2008

Anomalous mobility of polymerase chain reaction products after bisulfite treatment of DNA.

artículo científico publicado en 2004

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

artículo científico publicado en 2011

Application of DNA methyltransferases in targeted DNA methylation

artículo científico publicado en 2007

Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state.

artículo científico publicado en 2017

Application of histone modification-specific interaction domains as an alternative to antibodies

artículo científico publicado en 2014

Application of mixed peptide arrays to study combinatorial readout of chromatin modifications

artículo científico publicado en 2017

Application of modified histone peptide arrays in chromatin research

artículo científico publicado en 2018

Application of recombinant TAF3 PHD domain instead of anti-H3K4me3 antibody.

artículo científico publicado en 2016

Approaches and Guidelines for the Identification of Novel Substrates of Protein Lysine Methyltransferases

artículo científico publicado en 2016

Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.

artículo científico publicado en 2011

Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

artículo científico publicado en 2020

Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue.

artículo científico publicado en 2011

Automated purification of His6-tagged proteins allows exhaustive screening of libraries generated by random mutagenesis

artículo científico publicado en 2000

Avidin plate assay system for enzymatic characterization of a histone lysine methyltransferase

artículo científico publicado en 2005

BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

artículo científico publicado en 2010

Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

artículo científico publicado en 2002

Biochemistry and biology of mammalian DNA methyltransferases

artículo científico publicado en 2004

Biotechnological Applications of MBD Domain Proteins for DNA Methylation Analysis

scientific article published on 05 September 2019

Biotin-avidin microplate assay for the quantitative analysis of enzymatic methylation of DNA by DNA methyltransferases

artículo científico

Bisulfite sequencing Data Presentation and Compilation (BDPC) web server--a useful tool for DNA methylation analysis.

artículo científico publicado en 2008

Burning off DNA Methylation: New Evidence for Oxygen-Dependent DNA Demethylation

article

C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.

artículo científico publicado en 2011

Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme

artículo científico publicado en 2003

Changing the DNA recognition specificity of the EcoDam DNA-(adenine-N6)-methyltransferase by directed evolution

artículo científico publicado en 2009

Changing the target base specificity of the EcoRV DNA methyltransferase by rational de novo protein-design

artículo científico publicado en 2001

Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes.

artículo científico publicado en 2006

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

artículo científico publicado en 2010

Chromatin targeting of de novo DNA methyltransferases by the PWWP domain

artículo científico publicado en 2004

Circular Permutations in the Molecular Evolution of DNA Methyltransferases

artículo científico publicado en 1999

Clr4 specificity and catalytic activity beyond H3K9 methylation.

artículo científico publicado en 2017

Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase

artículo científico publicado en 2020

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

artículo científico publicado en 2020

Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

artículo científico publicado en 2016

Continuous enzymatic assay for histone lysine methyltransferases

artículo científico publicado en 2007

Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase

artículo científico

Correction of aberrant imprinting by allele-specific epigenome editing

artículo científico publicado en 2015

Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover

artículo científico publicado en 1998

Cyclical DNA methylation of a transcriptionally active promoter

artículo científico publicado en 2008

Cyclin D1 integrates G9a-mediated histone methylation

artículo científico publicado en 2019

Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences

artículo científico

DNA binding specificity of the EcoRV restriction endonuclease is increased by Mg2+ binding to a metal ion binding site distinct from the catalytic center of the enzyme.

artículo científico

DNA from Aspergillus flavus contains 5-methylcytosine

artículo científico publicado en 2001

DNA interaction of the CcrM DNA methyltransferase: a mutational and modeling study

artículo científico publicado en 2012

DNA methylation analysis by bisulfite conversion, cloning, and sequencing of individual clones

artículo científico publicado en 2009

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

artículo científico publicado en 2009

DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies

artículo científico publicado en 2012

DNA of Drosophila melanogaster contains 5-methylcytosine

artículo científico publicado en 2000

DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation

scientific article published on 24 July 2020

DNMT1-associated DNA methylation changes in cancer

artículo científico publicado en 2015

De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases

artículo científico publicado en 2005

Deoxyribonucleic Acid Methyl Transferases 3a and 3b Associate with the Nuclear Orphan Receptor COUP-TFI during Gene Activation

article

Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

artículo científico publicado en 2017

Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation

artículo científico publicado en 2014

Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

artículo científico publicado en 2011

Detection and analysis of enzymatic DNA methylation of oligonucleotide substrates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

artículo científico publicado en 2003

Detection and quantitation of the activity of DNA methyltransferases using a biotin/avidin microplate assay.

artículo científico publicado en 2008

Developing a programmed restriction endonuclease for highly specific DNA cleavage

artículo científico publicado en 2005

Development of an epigenetic tetracycline sensor system based on DNA methylation

artículo científico publicado en 2020

Distinct specificities of the <scp>HEMK2</scp> protein methyltransferase in methylation of glutamine and lysine residues

artículo científico publicado en 2024

Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.

artículo científico publicado en 2002

Does the Restriction EndonucleaseEcoRV Employ a Two-Metal-Ion Mechanism for DNA Cleavage?†

artículo científico publicado en 1997

Editorial: Alfred Pingoud (1945-2015).

artículo científico publicado en 2015

Editorial: Molecular Epigenetics: Connecting Human Biology and Disease with Little Marks

artículo científico publicado en 2011

Engineering novel restriction endonucleases: principles and applications

artículo científico publicado en 1996

Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects

artículo científico publicado en 2020

Enzymes that keep DNA under control: Meeting: DNA enzymes: structures and mechanisms

artículo científico publicado en 2001

Enzymology of Mammalian DNA Methyltransferases

artículo científico publicado en 2016

Epigenetics Europe conference. Munich, Germany, 8-9 September 2011.

artículo científico publicado en 2011

Epigenome Editing: State of the Art, Concepts, and Perspectives

artículo científico publicado en 2015

Evidence for an evolutionary relationship among type-II restriction endonucleases

artículo científico publicado en 1995

Evidence for substrate-assisted catalysis in the DNA cleavage of several restriction endonucleases

artículo científico publicado en 1995

Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity.

artículo científico publicado en 2018

Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns

artículo científico publicado en 2022

Flexibility of DNA in complex with proteins deduced from the distribution of bending angles observed by scanning force microscopy

artículo científico publicado en 1998

Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L.

artículo científico publicado en 2008

Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation

artículo científico publicado en 2011

Functional mapping of the EcoRV DNA methyltransferase by random mutagenesis and screening for catalytically inactive mutants

artículo científico publicado en 1998

Functional roles of conserved amino acid residues in DNA methyltransferases investigated by site-directed mutagenesis of the EcoRV adenine-N6-methyltransferase

artículo científico publicado en 1998

Genomic imprinting--the struggle of the genders at the molecular level

artículo científico publicado en 2013

German Human Methylome Project Started

article

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

scientific article published on 27 October 2020

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.

artículo científico publicado en 2017

H3K36me2/3 Binding and DNA Binding of the DNA Methyltransferase DNMT3A PWWP Domain Both Contribute to its Chromatin Interaction

artículo científico publicado en 2019

High-throughput purification of polyHis-tagged recombinant fusion proteins.

artículo científico publicado en 2003

Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase.

artículo científico publicado en 2011

Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems

artículo científico publicado en 1996

How does a DNA interacting enzyme change its specificity during molecular evolution? A site-directed mutagenesis study at the DNA binding site of the DNA-(adenine-N6)-methyltransferase EcoRV.

artículo científico publicado en 2001

Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism

scientific journal article

Identification of ICAD-derived peptides capable of inhibiting caspase-activated DNase

artículo científico publicado en 2012

Identification of novel inhibitors of DNA methylation by screening of a chemical library.

artículo científico publicado en 2013

Identification of protein lysine methylation readers with a yeast three-hybrid approach.

artículo científico publicado en 2018

Identification, cloning and heterologous expression of active [NiFe]-hydrogenase 2 from Citrobacter sp. SG in Escherichia coli

artículo científico publicado en 2015

Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a

artículo científico publicado en 2009

Intra- vs intersubunit communication in the homodimeric restriction enzyme EcoRV: Thr 37 and Lys 38 involved in indirect readout are only important for the catalytic activity of their own subunit

artículo científico publicado en 1998

Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein

artículo científico publicado en 1996

Investigation of H2AX methylation by the SUV39H2 protein lysine methyltransferase

artículo científico publicado en 2016

Investigation of the C-terminal domain of the bacterial DNA-(adenine N6)-methyltransferase CcrM.

artículo científico publicado en 2015

Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase

artículo científico publicado en 2015

Kinetic characterization of linear diffusion of the restriction endonuclease EcoRV on DNA.

artículo científico publicado en 1998

Kinetics of methylation and binding of DNA by the EcoRV adenine-N6 methyltransferase

artículo científico publicado en 1998

Label-free measurement of histone lysine methyltransferases activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

artículo científico publicado en 2014

Level of tissue differentiation influences the activation of a heat-inducible flower-specific system for genetic containment in poplar (Populus tremula L.).

artículo científico publicado en 2015

Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme

artículo científico publicado en 1996

Maintenance of species identity and controlling speciation of bacteria: a new function for restriction/modification systems? ⬇️

artículo científico publicado el 23 de octubre de 2003

Mapping of protein-protein interaction sites by the 'absence of interference' approach.

artículo científico publicado en 2007

Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase

artículo científico publicado en 2012

Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.

artículo científico publicado en 2016

Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy

artículo científico publicado en 2004

Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

artículo científico publicado en 2005

Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges

artículo científico publicado en 2016

Mechanistic Insights into the Allosteric Regulation of the Clr4 Protein Lysine Methyltransferase by Autoinhibition and Automethylation

scientific article published on 22 November 2020

Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase

artículo científico publicado en 2012

Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine

artículo científico publicado en 2010

Methods for determining activity and specificity of DNA binding and DNA cleavage by class II restriction endonucleases

artículo científico publicado en 2001

Methylation of recombinant mononucleosomes by DNMT3A demonstrates efficient linker DNA methylation and a role of H3K36me3

artículo científico publicado en 2022

Methylation sensitivity of restriction enzymes interacting with GATC sites

scientific article published on 01 May 2003

Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites

artículo científico publicado en 2017

Molecular Processes Connecting DNA Methylation Patterns with DNA Methyltransferases and Histone Modifications in Mammalian Genomes

article

Molecular Processes Connecting DNA Methylation Patterns with DNA Methyltransferases and Histone Modifications in Mammalian Genomes

scientific article published on 21 May 2019

Molecular enzymology of mammalian DNA methyltransferases

scientific journal article

Molecular enzymology of the EcoRV DNA-(Adenine-N (6))-methyltransferase: kinetics of DNA binding and bending, kinetic mechanism and linear diffusion of the enzyme on DNA.

artículo científico

Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases

scientific journal article

Multimerization of the Dnmt3a DNA Methyltransferase and Its Functional Implications

artículo científico publicado el 1 de enero de 2013

Mutational Analysis of the Function of Gln115 in the EcoRI Restriction Endonuclease, a Critical Amino Acid for Recognition of the Inner Thymidine Residue in the Sequence -GAATTC- and for Coupling Specific DNA Binding to Catalysis

article

Mutational analysis of target base flipping by the EcoRV adenine-N6 DNA methyltransferase

artículo científico publicado en 1999

Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.

artículo científico publicado en 2006

Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L

artículo científico publicado en 2006

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns

artículo científico publicado en 2019

New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analyses

artículo científico publicado en 2009

New concepts in DNA methylation

artículo científico publicado en 2014

Non-imprinted allele-specific DNA methylation on human autosomes.

artículo científico publicado en 2009

Non-radioactive protein lysine methyltransferase microplate assay based on reading domains

artículo científico publicado en 2013

Nucleosome stability measured in situ by automated quantitative imaging.

artículo científico publicado en 2017

Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L.

artículo científico publicado en 2011

On the Divalent Metal Ion Dependence of DNA Cleavage by Restriction Endonucleases of the EcoRI Family

scientific article published on 13 August 2009

On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2 ⬇️

artículo científico publicado el 30 de noviembre de 2011

On the Substrate Specificity of DNA Methyltransferases

artículo científico publicado en 1999

On the enzymatic properties of Dnmt1: specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme

artículo científico publicado en 2006

On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target

artículo científico publicado en 2000

Oxygen, epigenetic signaling, and the evolution of early life

artículo científico publicado en 2013

PCR-based random mutagenesis method using spiked oligonucleotides to randomize selected parts of a gene without any wild-type background

article

PWWP-DOMAIN INTERACTOR OF POLYCOMBS11 interacts with Polycomb-group proteins and histones and regulates Arabidopsis flowering and development.

artículo científico publicado en 2018

Pausing of the restriction endonuclease EcoRI during linear diffusion on DNA.

artículo científico

Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation

artículo científico publicado en 2008

Phosphorylation of serine-515 activates the Mammalian maintenance methyltransferase Dnmt1.

artículo científico publicado en 2007

Phylogeny of Methylomes

scientific article published in Science

Pmt1, a Dnmt2 homolog in Schizosaccharomyces pombe, mediates tRNA methylation in response to nutrient signaling.

artículo científico publicado en 2012

Probing the DNA interface of the EcoRV DNA-(adenine-N6)-methyltransferase by site-directed mutagenesis, fluorescence spectroscopy, and UV cross-linking

artículo científico publicado en 2002

Probing the indirect readout of the restriction enzyme EcoRV. Mutational analysis of contacts to the DNA backbone

artículo científico publicado en 1996

Profound Flanking Sequence Preference of Dnmt3a and Dnmt3b Mammalian DNA Methyltransferases Shape the Human Epigenome

artículo científico publicado en 2005

Protein engineering of the restriction endonuclease EcoRV . Structure-guided design of enzyme variants that recognize the base pairs flanking the recognition site

artículo científico publicado en 1998

Protein engineering of the restriction endonuclease EcoRV: replacement of an amino acid residue in the DNA binding site leads to an altered selectivity towards unmodified and modified substrates

artículo científico

Protein lysine methyltransferase G9a acts on non-histone targets

artículo científico publicado en 2008

Putting the pieces together: histone H2B ubiquitylation directly stimulates histone H3K79 methylation

artículo científico publicado en 2008

Quality of histone modification antibodies undermines chromatin biology research

artículo científico publicado en 2015

Rapid synthesis of new DNMT inhibitors derivatives of procainamide

artículo científico publicado en 2011

Reading and writing DNA methylation

artículo científico publicado en 2008

Recognition and cleavage of DNA by type-II restriction endonucleases

artículo científico publicado en 1997

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

artículo científico publicado en 2014

Reversible inactivation of the CG specific SssI DNA (cytosine-C5)-methyltransferase with a photocleavable protecting group

artículo científico publicado en 2007

Role of somatic cancer mutations in human protein lysine methyltransferases

artículo científico publicado en 2014

Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate

scientific article published on 16 September 2020

Silencing of Gene Expression by Targeted DNA Methylation: Concepts and Approaches ⬇️

artículo científico publicado el 1 de enero de 2010

Site-directed mutagenesis by polymerase chain reaction

artículo científico publicado en 2002

Site-directed mutagenesis in the catalytic center of the restriction endonuclease EcoRI.

artículo científico publicado en 1995

Somatic cancer mutations in the DNMT2 tRNA methyltransferase alter its catalytic properties

artículo científico publicado en 2015

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex

artículo científico publicado en 2017

Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme

artículo científico publicado en 2015

Specific DNMT3C flanking sequence preferences facilitate methylation of young murine retrotransposons

artículo científico publicado en 2024

Specificity Analysis of Histone Modification-Specific Antibodies or Reading Domains on Histone Peptide Arrays

artículo científico publicado en 2015

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

article

Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays

artículo científico publicado en 2014

Specificity of DNA binding and methylation by the M.FokI DNA methyltransferase

artículo científico publicado en 2000

Specificity of DNA triple helix formation analyzed by a FRET assay

artículo científico publicado en 2002

Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.

artículo científico publicado en 2012

Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins

artículo científico publicado en 2008

Specificity of the SUV4-20H1 and SUV4-20H2 protein lysine methyltransferases and methylation of novel substrates

artículo científico publicado en 2016

Stopped-flow and mutational analysis of base flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase

artículo científico publicado en 2004

Structural and biochemical characterization of a new Mg(2+) binding site near Tyr94 in the restriction endonuclease PvuII

artículo científico publicado en 2003

Structural and biochemical insight into the mechanism of dual CpG site binding and methylation by the DNMT3A DNA methyltransferase

artículo científico publicado en 2021

Structure and function of mammalian DNA methyltransferases.

artículo científico publicado en 2010

Structure and function of type II restriction endonucleases

artículo científico publicado en 2001

Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase

artículo científico publicado en 2006

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

artículo científico publicado en 2007

Structure prediction of the EcoRV DNA methyltransferase based on mutant profiling, secondary structure analysis, comparison with known structures of methyltransferases and isolation of catalytically inactive single mutants

article

Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates

artículo científico publicado en 2016

Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

artículo científico publicado en 2014

Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes

artículo científico publicado en 1993

Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1.

artículo científico publicado en 2014

Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)

artículo científico publicado en 2013

Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.

artículo científico publicado en 2015

Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity

artículo científico publicado en 2012

Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells

artículo científico publicado en 2014

Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain

artículo científico publicado en 2014

The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

artículo científico publicado en 2011

The Caulobacter crescentus DNA-(adenine-N6)-methyltransferase CcrM methylates DNA in a distributive manner.

artículo científico

The DNMT3A R882H mutant displays altered flanking sequence preferences

artículo científico publicado en 2018

The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes

artículo científico publicado en 2018

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

artículo científico publicado en 2004

The Dnmt2 RNA methyltransferase homolog of Geobacter sulfurreducens specifically methylates tRNA-Glu

artículo científico publicado en 2014

The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation

artículo científico publicado en 2010

The Escherichia coli dam DNA methyltransferase modifies DNA in a highly processive reaction

artículo científico publicado en 2002

The Flavobacterium okeanokoites adenine-N6-specific DNA-methyltransferase M.FokI is a tandem enzyme of two independent domains with very different kinetic properties.

artículo científico publicado en 1998

The M.EcoRV DNA-(adenine N6)-methyltransferase uses DNA bending for recognition of an expanded EcoDam recognition site.

artículo científico publicado en 2007

The Mechanism of DNA Cleavage by the Type II. Restriction Enzyme EcoRV: Asp36 Is Not Directly Involved in DNA Cleavage but Serves to Couple Indirect. Readout to Catalysis

artículo científico publicado en 1998

The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA.

artículo científico publicado en 2016

The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues.

artículo científico publicado en 2012

The SUV39H1 Protein Lysine Methyltransferase Methylates Chromatin Proteins Involved in Heterochromatin Formation and VDJ Recombination

artículo científico publicado en 2017

The Tudor domain of the PHD finger protein 1 is a dual reader of lysine trimethylation at lysine 36 of histone H3 and lysine 27 of histone variant H3t.

artículo científico publicado en 2013

The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism

artículo científico publicado en 2013

The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding

artículo científico publicado en 2009

The application of next generation sequencing in DNA methylation analysis

artículo científico publicado en 2010

The cytosine N4-methyltransferase M.PvuII also modifies adenine residues

artículo científico publicado en 2001

The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates

artículo científico publicado en 2018

The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity.

artículo científico publicado en 2003

The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols.

artículo científico publicado en 2011

The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

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