Lista de obras - Karolien De Bosscher - Dominio Público Uruguay

A Dissociated Glucocorticoid Receptor Modulator Reduces Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

scientific article published on 05 March 2012

A fully dissociated compound of plant origin for inflammatory gene repression

artículo científico publicado en 2005

A paradigm for gene regulation: inflammation, NF-kappaB and PPAR.

artículo científico publicado en 2003

A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis

artículo científico publicado en 2008

Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a.

artículo científico publicado en 2009

Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

artículo científico publicado en 2015

Adrenal hormones mediate disease tolerance in malaria

artículo científico publicado en 2018

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

artículo científico publicado en 2008

An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation

scientific article published on 13 January 2011

Analysis of Smad nucleocytoplasmic shuttling in living cells

artículo científico publicado en 2004

Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis

artículo científico publicado en 2009

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.

artículo científico publicado en 2016

Circumventing glucocorticoid-mediated hyperinsulinemia via the activation of PPARalpha.

artículo científico publicado en 2009

Classic glucocorticoids versus non-steroidal glucocorticoid receptor modulators: survival of the fittest regulator of the immune system?

artículo científico publicado en 2010

Co-activation of GR and PPARγ in murine skin prevents worsening of atopic march

artículo científico publicado en 2017

Cofactor profiling of the glucocorticoid receptor from a cellular environment

artículo científico publicado en 2014

Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor

artículo científico publicado en 2016

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

artículo científico publicado en 2021

Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells

artículo científico publicado en 2012

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

artículo científico publicado en 2013

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

artículo científico publicado en 2017

Correction: Compound A, a Dissociated Glucocorticoid Receptor Modulator, Inhibits T-bet (Th1) and Induces GATA-3 (Th2) Activity in Immune Cells

artículo científico publicado en 2012

Critical Roles of Endogenous Glucocorticoids for Disease Tolerance in Malaria

scientific article published on 09 October 2019

Cross-talk between steroids and NF-κB: what language? ⬇️

artículo científico publicado el 1 de julio de 1998

Crosstalk between TNF and glucocorticoid receptor signaling pathways

artículo científico publicado en 2010

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

artículo científico publicado en 2009

DNA Binding-Independent Induction of IκBα Gene Transcription by PPARα

artículo científico publicado en 2002

Daucane esters from laserwort (Laserpitium latifolium L.) inhibit cytokine and chemokine production in human lung epithelial cells

artículo científico publicado en 2017

Delayed development of the protective IL-17A response following a Giardia muris infection in neonatal mice.

artículo científico publicado en 2019

Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue

artículo científico publicado en 2015

Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts

artículo científico publicado en 2009

Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells

artículo científico publicado en 2010

Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies

artículo científico publicado en 2018

Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells

artículo científico

GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.

artículo científico publicado en 2016

Giardia muris infection in mice is associated with a protective interleukin 17A response and induction of peroxisome proliferator-activated receptor alpha

artículo científico publicado en 2014

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

artículo científico publicado en 2017

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

scientific article published on 25 June 2018

Glucocorticoid receptor mutants: man-made tools for functional research

artículo científico publicado en 2011

Glucocorticoid receptors: finding the middle ground

artículo científico publicado en 2017

Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: possible partners in the combat against inflammation

artículo científico publicado en 2008

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

artículo científico publicado en 2020

Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds ⬇️

scientific article published on June 2009

Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma.

artículo científico publicado en 2009

How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer

artículo científico publicado en 2021

How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines

artículo científico publicado en 2014

Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion

artículo científico publicado en 2014

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?

artículo científico publicado en 2020

In vitro inhibition of the transcription factor NF-κB and cyclooxygenase by bamboo extracts

artículo científico publicado en 2013

Inhibition of cytokine production by the herbicide atrazine. Search for nuclear receptor targets

artículo científico publicado en 2003

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia

artículo científico publicado en 2017

Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin

artículo científico publicado en 2017

Involvement of the Glucocorticoid Receptor in Pro-inflammatory Transcription Factor Inhibition by Daucane Esters from Laserpitium zernyi

artículo científico publicado en 2017

Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignancies

scientific article published on 17 September 2020

MAPPIT: a protein interaction toolbox built on insights in cytokine receptor signaling

artículo científico publicado en 2011

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses

scientific article published on 09 August 2019

Minireview: latest perspectives on antiinflammatory actions of glucocorticoids

artículo científico publicado en 2008

Mitogen- and stress-activated protein kinase 1 MSK1 regulates glucocorticoid response element promoter activity in a glucocorticoid concentration-dependent manner

artículo científico publicado en 2013

Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics

artículo científico publicado en 2016

Molecular Actions of PPARα in Lipid Metabolism and Inflammation

artículo científico publicado en 2018

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells

artículo científico publicado en 2004

Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

scientific article published on 17 April 2020

Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2.

artículo científico publicado en 2011

PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB

scholarly article

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

artículo científico publicado en 2014

Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK.

artículo científico publicado en 2017

Proteome-scale Binary Interactomics in Human Cells

artículo científico publicado en 2016

Recurrent mutation in the first zinc finger of the orphan nuclear receptor NR2E3 causes autosomal dominant retinitis pigmentosa

artículo científico publicado en 2007

Risks and benefits of corticosteroids in arthritic diseases in the clinic

scientific article published on 10 April 2019

Role of glucocorticoids in dopamine-related neuropsychiatric disorders

artículo científico publicado en 2005

Selective Glucocorticoid Receptor modulators

artículo científico publicado en 2010

Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex

artículo científico publicado en 2024

Selective glucocorticoid receptor modulation maintains bone mineral density in mice

artículo científico publicado en 2012

Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds

artículo científico publicado en 2015

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

artículo científico publicado en 2013

Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems

artículo científico publicado en 2008

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

artículo científico publicado en 2015

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

scientific article published on 10 June 2019

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity

artículo científico publicado en 2017

Targeting inflammation using selective glucocorticoid receptor modulators

artículo científico publicado en 2010

The HAT/HDAC interplay: multilevel control of STAT signaling

artículo científico

The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases

artículo científico publicado en 2016

The Sin3a repressor complex is a master regulator of STAT transcriptional activity

artículo científico publicado en 2012

The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages

scientific article published on 14 September 2018

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression

artículo científico publicado en 2003

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice

article

The versatile role of MSKs in transcriptional regulation.

artículo científico publicado en 2009

Therapeutic implications of the nuclear factor-kappaB/nuclear receptor cross-talk

artículo científico publicado en 2008

ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation

artículo científico publicado en 2021

Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium

scientific article published on 11 September 2020

Lista de obras de Karolien De Bosscher

A Dissociated Glucocorticoid Receptor Modulator Reduces Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

A fully dissociated compound of plant origin for inflammatory gene repression

A paradigm for gene regulation: inflammation, NF-kappaB and PPAR.

A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis

Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a.

Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept

Adrenal hormones mediate disease tolerance in malaria

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition

An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation

Analysis of Smad nucleocytoplasmic shuttling in living cells

Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.

Circumventing glucocorticoid-mediated hyperinsulinemia via the activation of PPARalpha.

Classic glucocorticoids versus non-steroidal glucocorticoid receptor modulators: survival of the fittest regulator of the immune system?

Co-activation of GR and PPARγ in murine skin prevents worsening of atopic march

Cofactor profiling of the glucocorticoid receptor from a cellular environment

Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor

Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation

Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies

Correction: Compound A, a Dissociated Glucocorticoid Receptor Modulator, Inhibits T-bet (Th1) and Induces GATA-3 (Th2) Activity in Immune Cells

Critical Roles of Endogenous Glucocorticoids for Disease Tolerance in Malaria

Cross-talk between steroids and NF-κB: what language? ⬇️

Crosstalk between TNF and glucocorticoid receptor signaling pathways

Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases

DNA Binding-Independent Induction of IκBα Gene Transcription by PPARα

Daucane esters from laserwort (Laserpitium latifolium L.) inhibit cytokine and chemokine production in human lung epithelial cells

Delayed development of the protective IL-17A response following a Giardia muris infection in neonatal mice.

Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue

Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts

Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells

Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies

Epicutaneous sensitization to house dust mite allergen requires interferon regulatory factor 4-dependent dermal dendritic cells

GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.

Giardia muris infection in mice is associated with a protective interleukin 17A response and induction of peroxisome proliferator-activated receptor alpha

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor

Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice

Glucocorticoid receptor mutants: man-made tools for functional research

Glucocorticoid receptors: finding the middle ground

Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: possible partners in the combat against inflammation

Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system

Hop (Humulus lupulus)-derived bitter acids as multipotent bioactive compounds ⬇️

Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma.

How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer

How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines

Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?

In vitro inhibition of the transcription factor NF-κB and cyclooxygenase by bamboo extracts

Inhibition of cytokine production by the herbicide atrazine. Search for nuclear receptor targets

Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia

Interplay between barrier epithelial cells and dendritic cells in allergic sensitization through the lung and the skin

Involvement of the Glucocorticoid Receptor in Pro-inflammatory Transcription Factor Inhibition by Daucane Esters from Laserpitium zernyi

Latest perspectives on glucocorticoid-induced apoptosis and resistance in lymphoid malignancies

MAPPIT: a protein interaction toolbox built on insights in cytokine receptor signaling

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses

Minireview: latest perspectives on antiinflammatory actions of glucocorticoids

Mitogen- and stress-activated protein kinase 1 MSK1 regulates glucocorticoid response element promoter activity in a glucocorticoid concentration-dependent manner

Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics

Molecular Actions of PPARα in Lipid Metabolism and Inflammation

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells

Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

Opposed regulation of type I IFN-induced STAT3 and ISGF3 transcriptional activities by histone deacetylases (HDACS) 1 and 2.

PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

Plasmodium berghei NK65 in Combination with IFN-γ Induces Endothelial Glucocorticoid Resistance via Sustained Activation of p38 and JNK.

Proteome-scale Binary Interactomics in Human Cells

Recurrent mutation in the first zinc finger of the orphan nuclear receptor NR2E3 causes autosomal dominant retinitis pigmentosa

Risks and benefits of corticosteroids in arthritic diseases in the clinic

Role of glucocorticoids in dopamine-related neuropsychiatric disorders

Selective Glucocorticoid Receptor modulators

Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex

Selective glucocorticoid receptor modulation maintains bone mineral density in mice

Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds

Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.

Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity