Lista de obras - James Broach - Dominio Público Uruguay

A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress

artículo científico publicado en 2014

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

artículo científico publicado en 2004

A novel clustering approach and prediction of optimal number of clusters: global optimum search with enhanced positioning

A novel clustering approach: Global optimum search with enhanced positioning

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists

artículo científico publicado en 2002

A rapid technique for the visualization of live immobilized yeast cells

artículo científico publicado en 2006

ATP-dependent specific binding of Tn3 transposase to Tn3 inverted repeats

artículo científico publicado en 1985

Acylation and prenylation of proteins

artículo científico publicado en 1990

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

artículo científico publicado en 2017

Assay for adhesion and agar invasion in S. cerevisiae

artículo científico publicado en 2006

Autoregulation of 2 micron circle gene expression provides a model for maintenance of stable plasmid copy levels

artículo científico publicado en 1988

CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1

artículo científico publicado en 2001

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

article

Cell fates in C. elegans: in medias ras.

artículo científico

Chromatin remodelers clear nucleosomes from intrinsically unfavorable sites to establish nucleosome-depleted regions at promoters

artículo científico publicado en 2011

Chromatin-dependent transcription factor accessibility rather than nucleosome remodeling predominates during global transcriptional restructuring in Saccharomyces cerevisiae

artículo científico publicado en 2009

Chromosomal boundaries in S. cerevisiae.

artículo científico publicado en 2001

Clonal evolution in paired endometrial intraepithelial neoplasia/atypical hyperplasia and endometrioid adenocarcinoma.

artículo científico publicado en 2017

Cloning genes by complementation in yeast

artículo científico publicado en 1991

Complete Genome Sequences of the Human Pathogen Paenibacillus thiaminolyticus Mbale and Type Strain P. thiaminolyticus NRRL B-4156

scientific article published on 09 April 2020

Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.

artículo científico publicado en 2003

Correspondence of yeast UAA suppressors to cloned tRNASerUCA genes

artículo científico publicado en 1981

Creation of GPCR-based chemical sensors by directed evolution in yeast

article by Addison D Ault & James Broach published January 2006 in Protein Engineering Design and Selection

Cross-talk and decision making in MAP kinase pathways

article by Megan N. McClean et al published 28 January 2007 in Nature Genetics

Decoding complex chemical mixtures with a physical model of a sensor array

artículo científico publicado en 2011

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity

artículo científico publicado en 2005

Direct simulation of yeast 2-microns circle plasmid amplification

artículo científico publicado en 1992

Directional bias during mating type switching in Saccharomyces is independent of chromosomal architecture

artículo científico publicado en 2002

Do cells think?

artículo científico publicado en 2007

Erratum: Corrigendum: Cross-talk and decision making in MAP kinase pathways

scholarly article published in Nature Genetics

Evaluation of normalization and pre-clustering issues in a novel clustering approach: global optimum search with enhanced positioning

artículo científico

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

artículo científico publicado en 2020

Expansion of C9ORF72 in amyotrophic lateral sclerosis correlates with brain-computer interface performance.

artículo científico publicado en 2017

Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists

artículo científico publicado en 2009

Functional homology of mammalian and yeast RAS genes.

artículo científico publicado en 1985

Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated

artículo científico publicado en 1979

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins.

artículo científico publicado en 1984

Genetic analysis of yeast RAS1 and RAS2 genes.

artículo científico publicado en 1984

Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research

artículo científico publicado en 2014

Genetic properties of chromosomally integrated 2μ plasmid DNA in yeast

artículo científico publicado en 1982

Genetic selection in Saccharomyces of mutant mammalian adenylyl cyclases with elevated basal activities

artículo científico publicado en 2001

Glucose regulates transcription in yeast through a network of signaling pathways

artículo científico publicado en 2009

High hydrostatic pressure activates gene expression that leads to ethanol production enhancement in a Saccharomyces cerevisiae distillery strain

artículo científico publicado en 2013

High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance

artículo científico publicado en 2012

Histidine regulation in Salmonella typhimurium. XVI. A sensitive radiochemical assay for histidinol dehydrogenase

artículo científico publicado en 1975

How Saccharomyces responds to nutrients

artículo científico publicado en 2008

Identification and mapping of the transcriptional and translational products of the yeast plasmid, 2mu circle

artículo científico publicado en 1979

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

artículo científico publicado en 2017

Identification of sites required for repression of a silent mating type locus in yeast

artículo científico publicado en 1984

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.

artículo científico publicado en 1998

Immunological analysis of yeast chromatin

article

In yeast, RAS proteins are controlling elements of adenylate cyclase.

artículo científico publicado en 1985

Inhibition of the Platelet-activating factor receptor for the treatment of Amyotrophic Lateral Sclerosis?

Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway

artículo científico publicado en 2010

Isolation and analysis of recombinant DNA molecules containing yeast DNA.

artículo científico publicado en 1978

Making good neighbors: The right fence for the right job

Making the right choice--long-range chromosomal interactions in development

artículo científico publicado en 2004

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly.

artículo científico publicado en 2017

Metastin and its variant forms suppress migration of pancreatic cancer cells

artículo científico publicado en 2004

Microarray data mining: a novel optimization-based approach to uncover biologically coherent structures

artículo científico publicado en 2008

Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions

artículo científico publicado en 2009

Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries

artículo científico publicado en 2003

Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast

artículo científico publicado en 2003

Mutations in the nucleosome core enhance transcriptional silencing

artículo científico publicado en 2005

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses.

artículo científico publicado en 2013

Nucleotide degradation and ribose salvage in yeast

artículo científico publicado en 2013

Nutritional Control of Growth and Development in Yeast ⬇️

artículo científico publicado el 1 de septiembre de 2012

Oncogenes and cell proliferation

artículo científico publicado en 1995

PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p

artículo científico publicado en 2004

Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants

scientific article published on 01 September 2020

Ph.D. Training in Cancer Biology

artículo científico publicado en 2008

Phosphorylation and nuclear transit modulate the balance between normal function and terminal aggregation of the yeast RNA-binding protein Ssd1.

artículo científico publicado en 2017

Predicting cellular growth from gene expression signatures

artículo científico publicado en 2009

Propagation and expression of cloned genes in yeast: 2-microns circle-based vectors

artículo científico publicado en 1990

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae

artículo científico publicado en 2007

Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6.

artículo científico publicado en 2009

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.

scientific article published on January 1991

Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression

artículo científico publicado en 2003

Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast

artículo científico publicado en 2004

Ras-regulated signaling processes in Saccharomyces cerevisiae

artículo científico publicado en 1991

Recombination within the yeast plasmid 2mu circle is site-specific

artículo científico publicado en 1982

Regulation of transcription in expressed and unexpressed mating type cassettes of yeast

scientific article published in Nature

Regulation of yeast pyruvate kinase by ultrasensitive allostery independent of phosphorylation

artículo científico publicado en 2012

SRV2, a gene required for RAS activation of adenylate cyclase in yeast

artículo científico publicado en 1990

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

artículo científico publicado en 2007

Sense and sensibility: nutritional response and signal integration in yeast

artículo científico publicado en 2004

Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements

artículo científico publicado en 2001

Single-Cell Observations Reveal Intermediate Transcriptional Silencing States

article by Eugenia Y. Xu et al published July 2006 in Molecular Cell

Site-specific recombination promotes plasmid amplification in yeast

artículo científico publicado en 1986

Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

artículo científico publicado en 1998

Systems Biology and TOR

article published in 2010

The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection

artículo científico publicado en 2004

The Saccharomyces cerevisiae recombination enhancer biases recombination during interchromosomal mating-type switching but not in interchromosomal homologous recombination

artículo científico publicado en 2004

The dynamics of homologous pairing during mating type interconversion in budding yeast

artículo científico publicado en 2006

The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication

artículo científico publicado en 2009

The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing.

artículo científico publicado en 1999

The yeast environmental stress response regulates mutagenesis induced by proteotoxic stress

artículo científico publicado en 2013

The yeast genome undergoes significant topological reorganization in quiescence

artículo científico publicado en 2015

The yeast plasmid 2μ circle encodes components required for its high copy propagation

artículo científico publicado en 1983

Theoretical and computational studies of the glucose signaling pathways in yeast using global gene expression data

artículo científico publicado en 2003

Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene

artículo científico publicado en 1979

Vaginal microbiome topic modeling of laboring Ugandan women with and without fever

artículo científico publicado en 2021

Web alert Oncogenes and cell proliferation

artículo científico publicado en 1997

Yeast cells can access distinct quiescent states

artículo científico publicado en 2011

Lista de obras de James Broach

A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

A novel clustering approach and prediction of optimal number of clusters: global optimum search with enhanced positioning

A novel clustering approach: Global optimum search with enhanced positioning

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists

A rapid technique for the visualization of live immobilized yeast cells

ATP-dependent specific binding of Tn3 transposase to Tn3 inverted repeats

Acylation and prenylation of proteins

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

Assay for adhesion and agar invasion in S. cerevisiae

Autoregulation of 2 micron circle gene expression provides a model for maintenance of stable plasmid copy levels

CAC3(MSI1) suppression of RAS2(G19V) is independent of chromatin assembly factor I and mediated by NPR1

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Cell fates in C. elegans: in medias ras.

Chromatin remodelers clear nucleosomes from intrinsically unfavorable sites to establish nucleosome-depleted regions at promoters

Chromatin-dependent transcription factor accessibility rather than nucleosome remodeling predominates during global transcriptional restructuring in Saccharomyces cerevisiae

Chromosomal boundaries in S. cerevisiae.

Clonal evolution in paired endometrial intraepithelial neoplasia/atypical hyperplasia and endometrioid adenocarcinoma.

Cloning genes by complementation in yeast

Complete Genome Sequences of the Human Pathogen Paenibacillus thiaminolyticus Mbale and Type Strain P. thiaminolyticus NRRL B-4156

Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2.

Correspondence of yeast UAA suppressors to cloned tRNASerUCA genes

Creation of GPCR-based chemical sensors by directed evolution in yeast

Cross-talk and decision making in MAP kinase pathways

Decoding complex chemical mixtures with a physical model of a sensor array

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity

Direct simulation of yeast 2-microns circle plasmid amplification

Directional bias during mating type switching in Saccharomyces is independent of chromosomal architecture

Do cells think?

Erratum: Corrigendum: Cross-talk and decision making in MAP kinase pathways

Evaluation of normalization and pre-clustering issues in a novel clustering approach: global optimum search with enhanced positioning

Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus

Expansion of C9ORF72 in amyotrophic lateral sclerosis correlates with brain-computer interface performance.

Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists

Functional homology of mammalian and yeast RAS genes.

Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins.

Genetic analysis of yeast RAS1 and RAS2 genes.

Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research

Genetic properties of chromosomally integrated 2μ plasmid DNA in yeast

Genetic selection in Saccharomyces of mutant mammalian adenylyl cyclases with elevated basal activities

Glucose regulates transcription in yeast through a network of signaling pathways

High hydrostatic pressure activates gene expression that leads to ethanol production enhancement in a Saccharomyces cerevisiae distillery strain

High hydrostatic pressure activates transcription factors involved in Saccharomyces cerevisiae stress tolerance

Histidine regulation in Salmonella typhimurium. XVI. A sensitive radiochemical assay for histidinol dehydrogenase

How Saccharomyces responds to nutrients

Identification and mapping of the transcriptional and translational products of the yeast plasmid, 2mu circle

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

Identification of sites required for repression of a silent mating type locus in yeast

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.

Immunological analysis of yeast chromatin

In yeast, RAS proteins are controlling elements of adenylate cyclase.

Inhibition of the Platelet-activating factor receptor for the treatment of Amyotrophic Lateral Sclerosis?

Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway

Isolation and analysis of recombinant DNA molecules containing yeast DNA.

Making good neighbors: The right fence for the right job

Making the right choice--long-range chromosomal interactions in development

Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly.

Metastin and its variant forms suppress migration of pancreatic cancer cells

Microarray data mining: a novel optimization-based approach to uncover biologically coherent structures

Microarray profiling of phage-display selections for rapid mapping of transcription factor-DNA interactions

Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries

Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast

Mutations in the nucleosome core enhance transcriptional silencing

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses.

Nucleotide degradation and ribose salvage in yeast

Nutritional Control of Growth and Development in Yeast ⬇️

Oncogenes and cell proliferation

PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p

Paenibacillus infection with frequent viral coinfection contributes to postinfectious hydrocephalus in Ugandan infants

Ph.D. Training in Cancer Biology

Phosphorylation and nuclear transit modulate the balance between normal function and terminal aggregation of the yeast RNA-binding protein Ssd1.

Predicting cellular growth from gene expression signatures

Propagation and expression of cloned genes in yeast: 2-microns circle-based vectors

Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae

Protein kinase A and TORC1 activate genes for ribosomal biogenesis by inactivating repressors encoded by Dot6 and its homolog Tod6.

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.

Rap1p and other transcriptional regulators can function in defining distinct domains of gene expression

Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast