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Lista de obras de Raghu Kalluri

A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

artículo científico publicado en 2004

A map of human breast cancer: new players in stromal-immune crosstalk

scientific article published on 10 September 2020

A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development

artículo científico publicado en 2002

A peek into cancer-associated fibroblasts: origins, functions and translational impact.

artículo científico publicado en 2018

A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion

scientific journal article

Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis

artículo científico publicado el 5 de febrero de 2012

Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.

artículo científico publicado en 2007

An unusual case of pulmonary-renal syndrome associated with defects in type IV collagen composition and anti-glomerular basement membrane autoantibodies

article

Angiogenesis is controlled by miR-27b associated with endothelial tip cells

artículo científico publicado en 2012

Angiotensin II Induces alpha3(IV) Collagen Expression in Cultured Murine Proximal Tubular Cells

scientific article published on 01 July 1999

Antiglomerular basement membrane autoantibodies are nonpathogenic in Wegener's granulomatosis

artículo científico publicado en 2003

Are there endogenous molecules that protect kidneys from injury? The case for bone morphogenic protein-7 (BMP-7).

artículo científico publicado en 2004

Assembly of Type IV Collagen

scientific article published in Journal of Biological Chemistry

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

artículo científico publicado en 2003

BMP-7 functions as a novel hormone to facilitate liver regeneration

artículo científico publicado en 2006

Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth

artículo científico publicado en 2008

Basement membranes: structure, assembly and role in tumour angiogenesis

artículo científico publicado en 2003

Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis

artículo científico publicado en 2008

Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion

artículo científico publicado en 2005

Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis

artículo científico publicado en 2009

Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney

artículo científico publicado en 2004

Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease

artículo científico publicado en 2006

Cancer without disease.

artículo científico publicado en 2004

Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth

artículo científico publicado en 2000

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

artículo científico publicado en 2005

Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis.

artículo científico publicado en 2005

Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis.

artículo científico publicado en 2012

Chapter 1. Molecular mechanism of type IV collagen-derived endogenous inhibitors of angiogenesis.

scientific article published on January 2008

Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor

artículo científico publicado en 2008

Chronic Bile Duct Injury Associated with Fibrotic Matrix Microenvironment Provokes Cholangiocarcinoma in p53-Deficient Mice

artículo científico publicado en 2006

Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population.

artículo científico publicado en 2009

Circulating endoglin concentration is not elevated in chronic kidney disease

artículo científico publicado en 2011

Contribution of bone microenvironment to leukemogenesis and leukemia progression

artículo científico publicado en 2009

Contribution of epithelial plasticity to renal transplantation-associated fibrosis

artículo científico publicado en 2010

Controlling angiogenesis in heart valves

artículo científico publicado en 2006

Conversion of vascular endothelial cells into multipotent stem-like cells

artículo científico publicado en 2010

Coordinate gene expression of the alpha3, alpha4, and alpha5 chains of collagen type IV. Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation

artículo científico publicado en 1996

Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner

artículo científico publicado el 27 de mayo de 2011

De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane

artículo científico publicado en 2006

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

artículo científico publicado en 2008

Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGFβ type II receptor independent manner

artículo científico publicado en 2011

Determinants of vascular permeability in the kidney glomerulus

artículo científico publicado en 2002

Differential expression of collagen IV isoforms in experimental glomerulosclerosis

artículo científico publicado en 1998

Differential expression of collagen type IV alpha-chains in the tubulointerstitial compartment in experimental chronic serum sickness nephritis

artículo científico publicado en 1999

Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells

scientific journal article

Dinosaur peptides suggest mechanisms of protein survival

artículo científico publicado en 2011

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

artículo científico publicado en 2007

Distinct antitumor properties of a type IV collagen domain derived from basement membrane

artículo científico publicado en 2000

Distribution of type IV collagen in the cochlea in Alport syndrome.

artículo científico publicado en 2005

Drug resistance associated with antiangiogenesis therapy

artículo científico publicado en 2009

Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program

artículo científico publicado en 2018

EMT: when epithelial cells decide to become mesenchymal-like cells

artículo científico publicado en 2009

Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes

artículo científico publicado en 2002

Emerging role of bacterial extracellular vesicles in cancer

artículo científico publicado en 2020

Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application

artículo científico publicado en 2005

Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype

artículo científico publicado en 2012

Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis

artículo científico publicado en 2020

Epithelial-Mesenchymal Transition

article from 2008

Exosomes in tumor microenvironment influence cancer progression and metastasis

artículo científico

Experimental Goodpasture's syndrome in Wistar-Kyoto rats immunized with α3 chain of type IV collagen

article

Experimental strategies to reverse chronic renal disease.

artículo científico publicado en 2004

Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.

artículo científico publicado en 2011

Expression of type IV collagen α1(IV)–α6(IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas

artículo científico publicado en 1997

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition

artículo científico publicado en 2007

Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis

artículo científico publicado en 2008

Fibroblasts in cancer

artículo científico publicado en 2006

Fibrosis and angiogenesis

artículo científico publicado en 2000

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

artículo científico publicado en 2005

Generic block on angiogenesis

artículo científico publicado en 2008

Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia

artículo científico publicado en 2007

Goodpasture syndrome

High affinity of anti-GBM antibodies from Goodpasture and transplanted Alport patients to alpha3(IV)NC1 collagen.

artículo científico publicado en 2000

Human Goodpasture anti-α3(IV)NC1 autoantibodies share structural determinants Rapid Communication

artículo científico publicado en 1998

Human antiglomerular basement membrane autoantibody disease in XenoMouse II.

artículo científico publicado en 2002

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

artículo científico publicado en 2003

Identification of IgG antibody response to SARS-CoV-2 spike protein and its receptor binding domain does not predict rapid recovery from COVID-19

artículo científico publicado en 2020

Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity

artículo científico publicado en 2008

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

artículo científico publicado en 2010

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

artículo científico publicado en 2013

Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly

artículo científico publicado en 2010

Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin

artículo científico publicado en 2001

Induction of B7-1 in podocytes is associated with nephrotic syndrome

article by Jochen Reiser et al published 15 May 2004 in Journal of Clinical Investigation

Induction of matrix metalloproteinases and collagenolysis in chick embryonic membranes before hatching

artículo científico publicado en 1999

Inhibition of monocyte chemoattractant protein-1 expression in tubular epithelium attenuates tubulointerstitial alteration in rat Goodpasture syndrome

artículo científico publicado en 2000

Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure

artículo científico publicado en 2012

Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

artículo científico publicado en 2007

Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function

artículo científico publicado en 2010

Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis

artículo científico publicado en 2010

Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors

artículo científico publicado en 2003

Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma

artículo científico publicado en 2011

Loss of β1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype

artículo científico publicado en 2013

Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease

artículo científico publicado en 2008

Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis

artículo científico publicado en 2015

Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction

artículo científico publicado en 2013

Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment.

artículo científico publicado en 2007

Mechanistic connection between inflammation and fibrosis

artículo científico publicado en 2010

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma

scientific article published on 27 August 2019

Modification of kidney barrier function by the urokinase receptor

artículo científico publicado en 2007

Molecular pathways: microRNAs as cancer therapeutics.

artículo científico publicado en 2012

NF- B-induced chromatin remodeling regulates angiogenesis

artículo científico publicado en 2010

NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele

artículo científico publicado en 2002

Nasal administration of recombinant rat alpha3(IV)NC1 prevents the development of experimental autoimmune glomerulonephritis in the WKY rat.

artículo científico publicado en 2005

Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria

scientific article published in Journal of Biological Chemistry

Origins of cardiac fibroblasts

artículo científico publicado en 2010

Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis

artículo científico publicado en 2009

Penetration of endothelial cell coated multicellular tumor spheroids by iron oxide nanoparticles

artículo científico publicado en 2012

Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway

scientific article published on January 2012

Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis

artículo científico publicado en 2018

Pre-eclampsia: connecting angiogenic and metabolic pathways

artículo científico publicado en 2010

Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions

artículo científico publicado en 2010

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

artículo científico publicado en 2021

Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses

artículo científico publicado en 2020

Proteinuria with and without renal glomerular podocyte effacement

artículo científico publicado en 2006

Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury.

artículo científico publicado en 2005

Reduced DNA gap repair in aging rat neuronal extracts and its restoration by DNA polymerase beta and DNA-ligase

artículo científico publicado en 2005

Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease

artículo científico publicado en 2003

Renal Fibrosis and Glomerulosclerosis in a New Mouse Model of Diabetic Nephropathy and Its Regression by Bone Morphogenic Protein-7 and Advanced Glycation End Product Inhibitors

article

Renal fibroblast-like cells in Goodpasture syndrome rats

artículo científico publicado en 2001

Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease

artículo científico publicado en 2009

Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3.

artículo científico publicado en 2013

Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute.

artículo científico publicado en 2010

Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease

artículo científico publicado en 2008

Role for transforming growth factor-beta1 in alport renal disease progression

artículo científico publicado en 1999

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation

artículo científico publicado en 2002

Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy

artículo científico publicado en 2004

Seminiferous Tubule Basement Membrane

scientific article published in Journal of Biological Chemistry

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

artículo científico publicado en 2011

Stem Cell-Based Therapy for Glomerular Diseases: An Evolving Concept

artículo científico publicado en 2008

Stem cell therapies benefit Alport syndrome

artículo científico publicado en 2009

Structural Features of Nephritogenic Lupus Autoantibodies

artículo científico publicado en 1997

Structural basis for the functions of endogenous angiogenesis inhibitors.

artículo científico publicado en 2005

Structure and function of basement membranes

artículo científico publicado en 2007

TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis.

artículo científico publicado en 2012

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

scientific journal article

Targeted Downregulation of Extracellular Nephrin in Human IgA Nephropathy

Targeting TGF-beta and the extracellular matrix in Marfan's syndrome

artículo científico publicado en 2008

The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen.

artículo científico publicado en 1996

The Kielin/chordin-like protein checkpoint constitutes a system of checks and balances in CKD.

artículo científico publicado en 2013

The VEGF pathway in cancer and disease: responses, resistance, and the path forward.

artículo científico publicado en 2012

The alpha 3 chain of type IV collagen induces autoimmune Goodpasture syndrome.

artículo científico publicado en 1994

The basics of epithelial-mesenchymal transition

artículo científico publicado en 2009

The biology of preeclampsia

artículo científico publicado en 2009

The biology, function, and biomedical applications of exosomes

artículo científico publicado en 2020

The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis

artículo científico publicado en 2004

The immunohistochemical composition of corneal basement membrane in keratoconus

article

The importance of cell-mediated immunity in the course and severity of autoimmune anti-glomerular basement membrane disease in mice

artículo científico publicado en 2003

The origin of fibroblasts and mechanism of cardiac fibrosis

artículo científico publicado en 2010

The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis

artículo científico publicado en 2011

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression

artículo científico publicado en 2004

Transcriptional regulation of epithelial-mesenchymal transition

artículo científico publicado en 2007

Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling.

artículo científico publicado en 2011

Tumor stroma derived biomarkers in cancer

artículo científico publicado en 2009

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis

artículo científico publicado en 2002

Type I collagen deletion in αSMA<sup>+</sup> myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer

artículo científico publicado en 2021

Type IV collagen α6 chain-derived noncollagenous domain 1 (α6(IV)NC1) inhibits angiogenesis and tumor growth

scientific article published on 01 April 2008

Type IV collagen-derived angiogenesis inhibitors

artículo científico publicado en 2007

Waking up dormant tumors

artículo científico publicado en 2011

Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome

artículo científico publicado en 2005

eRNAs are required for p53-dependent enhancer activity and gene transcription

artículo científico publicado en 2012

miR-21 Promotes Fibrogenic Epithelial-to-Mesenchymal Transition of Epicardial Mesothelial Cells Involving Programmed Cell Death 4 and Sprouty-1

artículo científico publicado el 18 de febrero de 2013

miR-29b moulds the tumour microenvironment to repress metastasis

artículo científico publicado el 1 de febrero de 2013

αSMA<sup>+</sup> fibroblasts suppress Lgr5<sup>+</sup> cancer stem cells and restrain colorectal cancer progression

scientific article published on 09 June 2021