Filtros de búsqueda

Lista de obras de Harald Grallert

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

artículo científico publicado en 2015

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A meta-analysis of gene expression signatures of blood pressure and hypertension

artículo científico publicado en 2015

A novel common variant in DCST2 is associated with length in early life and height in adulthood

artículo científico publicado en 2014

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave

artículo científico publicado en 2014

ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives

artículo científico publicado en 2017

APOA5 variants and metabolic syndrome in Caucasians

artículo científico publicado en 2007

Acute-phase serum amyloid A protein and its implication in the development of type 2 diabetes in the KORA S4/F4 study

artículo científico publicado en 2012

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation

artículo científico publicado en 2017

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

artículo científico publicado en 2019

An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes ⬇️

artículo científico publicado en 2011

An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker

artículo científico publicado en 2015

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing

artículo científico publicado en 2016

Analysis with the exome array identifies multiple new independent variants in lipid loci

artículo científico publicado en 2016

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium

artículo científico publicado en 2012

Association analysis between the prostaglandin E synthase 2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort

artículo científico publicado en 2009

Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study

artículo científico publicado en 2016

Association between functional FABP2 promoter haplotypes and body mass index: analyses of 8072 participants of the KORA cohort study

artículo científico publicado en 2009

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α.

artículo científico publicado en 2018

Association of a MTNR1B gene variant with fasting glucose and HOMA-B in children and adolescents with high BMI-SDS ⬇️

artículo científico publicado el 8 de noviembre de 2010

Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations

artículo científico publicado en 2007

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

artículo científico publicado en 2013

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans

artículo científico publicado en 2012

Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study

artículo científico publicado en 2016

Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations

artículo científico publicado en 2007

Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin

artículo científico publicado en 2010

Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.

artículo científico publicado en 2009

BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1

artículo científico publicado en 2010

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Cell specific eQTL analysis without sorting cells

Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1

artículo científico publicado en 2006

Changes in the serum metabolite profile in obese children with weight loss

artículo científico publicado en 2014

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

scholarly article published 11 February 2018

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data

artículo científico publicado en 2016

Characterization of whole-genome autosomal differences of DNA methylation between men and women

artículo científico publicado en 2015

Childhood obesity is associated with changes in the serum metabolite profile

artículo científico publicado en 2012

Common eye diseases in older adults of southern Germany: results from the KORA-Age study

artículo científico publicado en 2016

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele

article

Connecting genetic risk to disease end points through the human blood plasma proteome

scientific article published on 27 February 2017

Connecting genetic risk to disease endpoints through the human blood plasma proteome

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

DNA methylation and body-mass index: a genome-wide analysis

artículo científico publicado en 2014

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Development and application of genomic control methods for genome-wide association studies using non-additive models

artículo científico publicado en 2013

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Disentangling the genetics of lean mass

article

Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness.

artículo científico publicado en 2012

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis

artículo científico publicado en 2016

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

artículo científico publicado en 2011

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues

artículo científico publicado en 2016

Epigenetic regulation of glucose metabolism

artículo científico publicado en 2017

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

artículo científico publicado en 2013

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

artículo científico publicado en 2015

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

artículo científico publicado en 2016

Ernährungsgewohnheiten schlagen sich im Erbgut nieder

Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome

artículo científico publicado en 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample

artículo científico publicado en 2008

Evaluation of the prevalence and prospective clinical impact of the JAK2 V617F mutation in coronary patients

artículo científico publicado en 2014

Evidence for the Thr79Met polymorphism of the ileal fatty acid binding protein (FABP6) to be associated with type 2 diabetes in obese individuals

artículo científico publicado en 2009

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

artículo científico publicado en 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

artículo científico publicado en 2017

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

artículo científico publicado en 2015

Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa

artículo científico publicado en 2012

Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2.

artículo científico publicado en 2015

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

artículo científico publicado en 2018

First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study

artículo científico publicado en 2010

Gender-specific pathway differences in the human serum metabolome

artículo científico publicado en 2015

Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity

artículo científico publicado en 2013

Gene variants of monocyte chemoattractant protein 1 and components of metabolic syndrome in KORA S4, Augsburg

artículo científico publicado en 2007

Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome

artículo científico publicado en 2009

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

artículo científico publicado en 2014

Genetic evidence of assortative mating in humans

article

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

artículo científico publicado en 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations ov

artículo científico publicado en 2010

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes

artículo científico publicado en 2017

Genetic variants of lipase activity in chronic pancreatitis

artículo científico publicado en 2015

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

artículo científico publicado en 2015

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

artículo científico publicado en 2007

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

artículo científico publicado en 2014

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

artículo científico publicado en 2017

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.

artículo científico publicado en 2018

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study (GWAS) for molar-incisor hypomineralization (MIH).

artículo científico publicado en 2013

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy

artículo científico publicado en 2012

Genome-wide association study identifies five loci associated with lung function

artículo científico publicado en 2010

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

artículo científico publicado en 2017

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.

artículo científico publicado en 2015

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

artículo científico publicado en 2010

Genome-wide association study of kidney function decline in individuals of European descent

artículo científico publicado en 2014

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide methylation data mirror ancestry information

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Harmonization of study and reference data by PhaseLift: saving time when imputing study data

artículo científico publicado en 2014

IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4.

artículo científico publicado en 2006

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

artículo científico publicado en 2006

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

artículo científico publicado en 2018

IgG glycosylation and DNA methylation are interconnected with smoking

artículo científico publicado en 2017

Immediate reduction of serum citrulline but no change of steroid profile after initiation of metformin in individuals with type 2 diabetes

artículo científico publicado en 2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver

artículo científico publicado en 2016

Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

artículo científico publicado en 2017

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

artículo científico publicado en 2009

Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes

artículo científico publicado en 2012

Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS).

artículo científico publicado en 2010

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

artículo científico publicado en 2014

MTTP variants and body mass index, waist circumference and serum cholesterol level: Association analyses in 7582 participants of the KORA study cohort

artículo científico publicado en 2008

Mapping the genetic architecture of gene regulation in whole blood

artículo científico publicado en 2014

Maternal and fetal genetic contribution to gestational weight gain

article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Metabolomics reveals determinants of weight loss during lifestyle intervention in obese children

Mitochondrial DNA variants in obesity

artículo científico publicado en 2014

Mitochondrial GWA Analysis of Lipid Profile Identifies Genetic Variants to Be Associated with HDL Cholesterol and Triglyceride Levels

artículo científico publicado en 2015

Mitochondrial genetic variants identified to be associated with BMI in adults

artículo científico publicado en 2014

Modulation of insulin degrading enzyme activity and liver cell proliferation

artículo científico publicado en 2015

Multi-omic signature of body weight change: results from a population-based cohort study

artículo científico publicado en 2015

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity

artículo científico publicado en 2010

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants

artículo científico publicado en 2012

Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway

artículo científico publicado en 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No association between the ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German population.

artículo científico publicado en 2015

No impact of obesity susceptibility loci on weight regain after a lifestyle intervention in overweight children

artículo científico publicado en 2013

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry

artículo científico publicado en 2009

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

artículo científico publicado en 2014

Novel biomarkers for pre-diabetes identified by metabolomics

artículo científico publicado en 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Numerous Genes in Loci Associated With Body Fat Distribution Are Linked to Adipose Function

artículo científico publicado en 2016

Omics: Potential Role in Early-Phase Drug Development

article

On the potential of models for location and scale for genome-wide DNA methylation data

artículo científico publicado en 2014

PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort

artículo científico publicado en 2014

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146

artículo científico publicado en 2013

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway

artículo científico publicado en 2018

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

artículo científico publicado en 2012

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

artículo científico publicado en 2018

SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents

artículo científico publicado en 2011

SLC23A1polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women

artículo científico publicado en 2016

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

Targeted metabolomics identifies reliable and stable metabolites in human serum and plasma samples

artículo científico publicado en 2014

The Diabetes Risk Phenotype of Young Women With Recent Gestational Diabetes

artículo científico publicado en 2015

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

artículo científico publicado en 2018

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The stool microbiota of insulin resistant women with recent gestational diabetes, a high risk group for type 2 diabetes

artículo científico publicado en 2015

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article

Underlying genetic models of inheritance in established type 2 diabetes associations

artículo científico publicado en 2009

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

artículo científico publicado en 2017

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda