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Lista de obras de Josée Dupuis

A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets

artículo científico publicado en 2007

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A comparison of gene region simulation methods

artículo científico publicado en 2012

A comparison of visual and quantitative methods to identify interstitial lung abnormalities

artículo científico publicado en 2015

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

artículo científico publicado en 2014

A method of moments estimator for random effect multivariate meta-analysis

artículo científico publicado en 2012

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

artículo científico publicado en 2002

A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease

A unified framework for linkage and association analysis of quantitative traits

artículo científico publicado en 2007

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

Anterior Mediastinal Masses in the Framingham Heart Study: Prevalence and CT Image Characteristics

artículo científico publicado en 2015

Association Between Interstitial Lung Abnormalities and All-Cause Mortality

artículo científico publicado en 2016

Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

artículo científico publicado en 2015

Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study.

artículo científico publicado en 2015

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

artículo científico publicado en 2014

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

artículo científico publicado en 2002

Association of the IGF1 gene with fasting insulin levels

artículo científico publicado en 2016

Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study

artículo científico publicado en 2009

Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis

artículo científico publicado en 2011

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Association testing of the mitochondrial genome using pedigree data

artículo científico publicado en 2013

Atrial fibrillation: current knowledge and future directions in epidemiology and genomics

artículo científico publicado en 2011

Bivariate linkage study of proximal hip geometry and body size indices: the Framingham study

artículo científico publicado en 2007

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

artículo científico publicado en 2013

Cellular cholesterol efflux in heterozygotes for tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particle size

artículo científico publicado en 2000

Cerebral small vessel disease genomics and its implications across the lifespan

artículo científico publicado en 2020

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

artículo científico publicado en 2009

Clinical and genetic correlates of soluble P-selectin in the community

artículo científico publicado en 2007

Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study

artículo científico publicado en 2008

Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study

scientific article published on 02 October 2008

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

artículo científico publicado en 2010

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study

artículo científico publicado en 2013

Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study

artículo científico publicado en 2008

Comparison of multiple single-nucleotide variant association tests in a meta-analysis of Genetic Analysis Workshop 19 family and unrelated data

artículo científico publicado en 2016

Comparison of statistical approaches to rare variant analysis for quantitative traits.

artículo científico publicado en 2011

Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data

artículo científico publicado en 2005

Correction for multiple testing in a gene region

artículo científico publicado en 2013

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

artículo científico publicado en 2019

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

artículo científico publicado en 2016

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Detecting differentially methylated regions with multiple distinct associations

artículo científico publicado en 2021

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study.

artículo científico publicado en 2016

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Diurnal variation of serum alanine transaminase activity in chronic liver disease

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators

artículo científico publicado en 2009

Effect of linkage disequilibrium between markers in linkage and association analyses

artículo científico publicado en 2007

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

artículo científico publicado en 2011

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study.

artículo científico publicado en 2018

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

artículo científico publicado en 2017

Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies

artículo científico publicado en 2016

Evaluation of approaches to identify associated SNPs that explain the linkage evidence in nuclear families with affected siblings

artículo científico publicado en 2009

Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysis

artículo científico publicado en 2017

Evaluation of population stratification adjustment using genome-wide or exonic variants

scientific article published on 30 June 2020

Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases

artículo científico publicado en 2015

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Exo-proofreading, a versatile SNP scoring technology

artículo científico publicado en 2003

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Expectation maximization algorithm based haplotype relative risk (EM-HRR): test of linkage disequilibrium using incomplete case-parents trios

artículo científico publicado en 2005

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

artículo científico publicado en 2018

Galectin-3 Is Associated with Restrictive Lung Disease and Interstitial Lung Abnormalities

artículo científico publicado en 2016

Gene expression markers of age-related inflammation in two human cohorts

artículo científico publicado en 2015

General Framework for Meta-Analysis of Haplotype Association Tests

artículo científico publicado en 2016

Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci

artículo científico publicado en 2007

Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

artículo científico publicado en 2021

Genetic and non-genetic correlates of vitamins K and D.

artículo científico publicado en 2007

Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States

artículo científico publicado en 2011

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

artículo científico publicado en 2017

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. ⬇️

artículo científico publicado en 2010

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

artículo científico publicado en 2010

Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men

artículo científico publicado en 2006

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetically Driven Hyperglycemia Increases Risk of Coronary Artery Disease Separately From Type 2 Diabetes.

artículo científico publicado en 2017

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome scan of systemic biomarkers of vascular inflammation in the Framingham Heart Study: Evidence for susceptibility loci on 1q

article

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

artículo científico publicado en 2016

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

artículo científico publicado en 2013

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci

artículo científico publicado en 2011

Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic

artículo científico publicado en 2009

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis

artículo científico publicado en 2008

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

artículo científico publicado en 2012

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy

artículo científico publicado en 2012

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide association study of subclinical interstitial lung disease in MESA.

artículo científico publicado en 2017

Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project

artículo científico publicado en 2007

Genome-wide association with bone mass and geometry in the Framingham Heart Study

artículo científico publicado en 2007

Genome-wide association with diabetes-related traits in the Framingham Heart Study

artículo científico publicado en 2007

Genome-wide association with select biomarker traits in the Framingham Heart Study

artículo científico publicado en 2007

Genome-wide gene-environment interactions on quantitative traits using family data

artículo científico publicado en 2015

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

artículo científico publicado en 2012

Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD.

artículo científico publicado en 2012

Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study

artículo científico publicado en 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genotype score in addition to common risk factors for prediction of type 2 diabetes

artículo científico publicado en 2008

Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms

artículo científico publicado en 2007

Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy

artículo científico publicado en 2009

Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study

artículo científico publicado en 2008

Heritability of Atrial Fibrillation

artículo científico publicado en 2017

Hormone receptor status of breast tumors in black, Hispanic, and non-Hispanic white women. An analysis of 13,239 cases

artículo científico publicado en 1996

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

artículo científico publicado en 2017

Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems

artículo científico publicado en 2012

Identification of polymorphisms explaining a linkage signal: application to the GAW14 simulated data

artículo científico publicado en 2005

Identifying SNPs predictive of phenotype using random forests

artículo científico publicado en 2005

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Impact of common variation in bone-related genes on type 2 diabetes and related traits

artículo científico publicado en 2012

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

artículo científico publicado en 2013

Incident Type 2 Diabetes Risk is Influenced by Obesity and Diabetes in Social Contacts: a Social Network Analysis

artículo científico publicado en 2016

Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies.

artículo científico publicado en 2009

Incorporating gene-environment interaction in testing for association with rare genetic variants

artículo científico publicado en 2014

Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies

artículo científico publicado en 2017

Integrative Omics Approach to Identifying Genes Associated With Atrial Fibrillation

artículo científico publicado en 2019

Integrative pathway genomics of lung function and airflow obstruction

artículo científico publicado en 2015

Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies

artículo científico publicado en 2010

Interpreting Results of Large-Scale Genetic Association Studies

artículo científico publicado en 2007

Joint association analysis of a binary and a quantitative trait in family samples

artículo científico publicado en 2016

Joint modeling of linkage and association using affected sib-pair data

artículo científico publicado en 2007

Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study

artículo científico publicado en 2013

Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans

artículo científico publicado en 2014

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

artículo científico publicado en 2009

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

artículo científico publicado en 2014

Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels

artículo científico publicado en 2010

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

artículo científico publicado en 2015

MUC5B promoter polymorphism and interstitial lung abnormalities

artículo científico publicado en 2013

Mapping complex traits using Random Forests

artículo científico publicado en 2003

Mapping quantitative traits in unselected families: algorithms and examples

artículo científico publicado en 2009

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

artículo científico publicado en 2013

Meta-Analysis for Penalized Regression Methods with Multi-Cohort Genome-Wide Association Studies

artículo científico publicado en 2016

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function

artículo científico publicado en 2018

Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts

artículo científico publicado en 2012

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels

artículo científico publicado en 2014

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Metabolic factors and genetic risk mediate familial type 2 diabetes risk in the Framingham Heart Study

artículo científico publicado en 2015

MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage.

artículo científico publicado en 2017

Modeling gene-covariate interactions in sparse regression with group structure for genome-wide association studies

artículo científico publicado en 2015

Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels

artículo científico publicado en 2015

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

Multipoint linkage analysis of the pseudoautosomal regions, using affected sibling pairs

artículo científico publicado en 2000

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

artículo científico publicado en 2009

Network-guided sparse regression modeling for detection of gene-by-gene interactions

scientific article published on 18 April 2013

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

artículo científico publicado en 2012

Normal thymus in adults: appearance on CT and associations with age, sex, BMI and smoking

artículo científico publicado en 2015

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds

artículo científico

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

artículo científico publicado en 2019

Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits

artículo científico publicado en 2008

Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis

scientific article published on 01 December 2019

PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample

artículo científico publicado en 2006

Paraseptal emphysema: Prevalence and distribution on CT and association with interstitial lung abnormalities

artículo científico publicado en 2015

Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults

artículo científico publicado en 2015

Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21

article

Performance of statistical methods on CHARGE targeted sequencing data

artículo científico publicado en 2014

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

artículo científico publicado en 2016

Phenocopies for deafness and goiter development in a large inbred Brazilian kindred with Pendred's syndrome associated with a novel mutation in the PDS gene.

artículo científico publicado en 1999

Pleiotropic genes for metabolic syndrome and inflammation

artículo científico publicado en 2014

Pleural abnormalities in the Framingham Heart Study: prevalence and CT image features.

artículo científico publicado en 2017

Polygenic type 2 diabetes prediction at the limit of common variant detection

artículo científico publicado en 2014

Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans

artículo científico publicado en 2007

Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus

artículo científico publicado en 2006

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls

article

Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study

artículo científico publicado en 2006

Pulmonary cysts identified on chest CT: are they part of aging change or of clinical significance?

artículo científico publicado en 2015

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

artículo científico publicado en 2019

Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III).

artículo científico publicado en 2012

Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population

artículo científico publicado en 2010

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rare genetic variant analysis on blood pressure in related samples

artículo científico publicado en 2014

Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project

artículo científico publicado en 2016

Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe

artículo científico publicado en 2010

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection

artículo científico publicado en 2008

Revisiting heritability accounting for shared environmental effects and maternal inheritance

artículo científico publicado en 2014

Robust analysis of secondary phenotypes in case-control genetic association studies

artículo científico publicado en 2016

Selection of the most informative individuals from families with multiple siblings for association studies

artículo científico publicado en 2009

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sequence kernel association test for quantitative traits in family samples

artículo científico publicado en 2012

Sequence kernel association test for survival traits.

artículo científico publicado en 2014

Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women.

artículo científico publicado en 2017

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke

artículo científico publicado en 2015

Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

artículo científico publicado en 2020

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

Structured mating: Patterns and implications

artículo científico publicado en 2017

Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

artículo científico publicado en 2017

TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study

artículo científico publicado en 2009

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

artículo científico publicado en 2007

The Insulin Gene Variable Number Tandem Repeat and Risk of Type 2 Diabetes in a Population-Based Sample of Families and Unrelated Men and Women

article

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations

artículo científico publicado en 2009

The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study

artículo científico publicado en 2007

Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis

artículo científico publicado en 2011

Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations.

artículo científico publicado en 2018

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

artículo científico publicado en 2016

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

artículo científico publicado en 2016

Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study

artículo científico publicado en 2012

Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource

artículo científico publicado en 2012

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis

artículo científico publicado en 2016

United States Research Published in Major Surgical Journals Is Decreasing

artículo científico publicado en 1995

Using linkage analysis of large pedigrees to guide association analyses

artículo científico publicado en 2011

Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4

article

Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease

artículo científico publicado en 2011

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variants in the CNR1 and the FAAH genes and adiposity traits in the community

artículo científico publicado en 2009

Whole blood gene expression and atrial fibrillation: the Framingham Heart Study

artículo científico publicado en 2014

Whole blood gene expression and interleukin-6 levels

artículo científico publicado en 2014

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole genome sequence analyses of brain imaging measures in the Framingham Study

artículo científico publicado en 2017

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

scientific article published on 14 October 2020

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