Filtros de búsqueda

Lista de obras de Sandosh Padmanabhan

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

artículo científico publicado en 2016

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC Study): design and rationale of a family based randomized controlled trial in individuals with family history of premature coronary heart disease

artículo científico publicado en 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A collaborative model for capacity building of primary care physicians in the management of Hypertension in India

scientific article published on 01 July 2019

A randomized controlled crossover trial evaluating differential responses to antihypertensive drugs (used as mono- or dual therapy) on the basis of ethnicity: The comparIsoN oF Optimal Hypertension RegiMens; part of the Ancestry Informative Markers i

article

Acetaminophen use and change in blood pressure in a hypertensive population

article by Jesse Dawson et al published July 2013 in Journal of Hypertension

Acetaminophen use and risk of myocardial infarction and stroke in a hypertensive cohort

artículo científico publicado en 2015

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

Age at Menarche and Cardiometabolic Health: A Sibling Analysis in the Scottish Family Health Study

artículo científico publicado en 2018

Allopurinol and Cardiovascular Outcomes in Adults With Hypertension.

artículo científico publicado en 2016

Allopurinol initiation and change in blood pressure in older adults with hypertension

artículo científico publicado en 2014

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

artículo científico publicado en 2016

Antihypertensive pharmacogenetics: missed opportunity

artículo científico publicado el 1 de octubre de 2010

Are isolated populations better for studying genes that predispose to hypertension?

artículo científico publicado en 2009

Artificial intelligence in healthcare-opportunities and challenges

artículo científico publicado en 2021

Artificial intelligence in healthcare—the road to precision medicine

artículo científico publicado en 2021

Association between ADRA1A gene and the metabolic syndrome: candidate genes and functional counterpart in the PAMELA population

article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association between cognition and gene polymorphisms involved in thrombosis and haemostasis

artículo científico publicado en 2015

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

artículo científico publicado en 2012

Association between serum phosphate and calcium, long-term blood pressure, and mortality in treated hypertensive adults

artículo científico publicado en 2015

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Blood pressure loci identified with a gene-centric array

artículo científico publicado en 2011

Blood pressure response to patterns of weather fluctuations and effect on mortality

artículo científico publicado en 2013

Blood pressure-lowering activity of statins: a systematic literature review and meta-analysis of placebo-randomized controlled trials

artículo científico publicado en 2020

COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records

artículo científico publicado en 2022

Cardiac Troponin T and Troponin I in the General Population

artículo científico publicado en 2019

Cardiovascular diseases and G-protein β3 subunit gene (GNB3) in the era of genomewide scans

article

Chromosome 2p Shows Significant Linkage to Antihypertensive Response in the British Genetics of Hypertension Study

article

Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study.

artículo científico publicado en 2017

Clinical Trials in Pharmacogenomics and Stratified Medicine

Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.

artículo científico publicado en 2017

Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension

article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

artículo científico publicado en 2015

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Comparison between High-Sensitivity Cardiac Troponin T and Cardiac Troponin I in a Large General Population Cohort

artículo científico publicado en 2018

Contrasting mortality risks among subgroups of treated hypertensive patients developing new-onset diabetes

artículo científico publicado en 2015

Copy-number disorders are a common cause of congenital kidney malformations

artículo científico publicado en 2012

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

artículo científico publicado en 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

Development, Evaluation, and Comparison of Land Use Regression Modeling Methods to Estimate Residential Exposure to Nitrogen Dioxide in a Cohort Study

artículo científico publicado en 2016

Diastolic Blood Pressure J-Curve Phenomenon in a Tertiary-Care Hypertension Clinic

artículo científico publicado en 2019

Dietary Influence on Systolic and Diastolic Blood Pressure in the TwinsUK Cohort

scientific article published on 17 July 2020

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discontinuation of beta-blockers in cardiovascular disease: UK primary care cohort study

artículo científico publicado en 2012

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

artículo científico

Does a history of depression actually mediate smoking-related pain? Findings from a cross-sectional general population-based study.

artículo científico publicado en 2014

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium

artículo científico publicado en 2015

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

artículo científico publicado en 2015

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Elevated heart rate and cardiovascular outcomes in patients with coronary artery disease: clinical evidence and pathophysiological mechanisms

artículo científico publicado en 2010

Emerging face of genetics, genomics and diabetes

article

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies.

artículo científico publicado en 2018

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Evaluation of how gene-job strain interaction affects blood pressure in the PAMELA study

artículo científico publicado en 2011

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

artículo científico publicado en 2016

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

artículo científico publicado en 2017

Familial and phenotypic associations of the aldosterone Renin ratio

artículo científico publicado en 2009

Family history of premature cardiovascular disease: blood pressure control and long-term mortality outcomes in hypertensive patients

artículo científico publicado en 2013

Fibroblast Growth Factor 1 Gene and Hypertension

article

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

artículo científico publicado en 2015

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Fundamentals of Complex Trait Genetics and Association Studies

article

Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals

artículo científico publicado en 2019

Gene and environmental interactions according to the components of lifestyle modifications in hypertension guidelines

article

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

artículo científico publicado en 2009

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

artículo científico publicado en 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

artículo científico publicado en 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

artículo científico publicado en 2020

Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

artículo científico publicado en 2016

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

artículo científico publicado en 2018

Genetic and molecular aspects of hypertension

artículo científico

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

artículo científico publicado en 2019

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic basis of blood pressure and hypertension

artículo científico

Genetic causation: the end of parsimony?

scientific article published on 01 August 2009

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression

artículo científico publicado en 2020

Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction

scientific article published on 23 January 2020

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

artículo científico publicado en 2011

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants

artículo científico publicado en 2010

Genetically distinct subsets within ANCA-associated vasculitis

scientific journal article

Genetics and Hypertension: Which Information for Clinical Practice

article

Genetics and hypertension: is it time to change my practice?

artículo científico

Genetics of hypertension: from experimental animals to humans

artículo científico publicado en 2009

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

artículo científico publicado en 2016

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

artículo científico publicado en 2016

Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

artículo científico publicado en 2016

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

artículo científico publicado en 2017

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association studies of hypertension: light at the end of the tunnel

artículo científico publicado en 2010

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117)

article

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).

artículo científico publicado en 2017

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

article

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension

artículo científico publicado en 2010

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

artículo científico publicado en 2011

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

artículo científico publicado en 2017

Genomic approaches to coronary artery disease

artículo científico publicado en 2010

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

artículo científico publicado en 2013

Genomic determinants of hypertension with a focus on metabolomics and the gut microbiome

artículo científico publicado en 2020

Genomics and Pharmacogenomics of Lipid-Lowering Therapies

Genomics and Precision Medicine for Clinicians and Scientists in Hypertension

artículo científico publicado en 2017

Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification

artículo científico publicado en 2020

Genomics of elite sporting performance: what little we know and necessary advances

artículo científico

Genomics of hypertension

artículo científico publicado en 2017

Genomics of hypertension: the road to precision medicine

artículo científico publicado en 2020

Glutathione S-transferase variants and hypertension

artículo científico publicado en 2008

HLA has strongest association with IgA nephropathy in genome-wide analysis

artículo científico publicado en 2010

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

artículo científico publicado en 2015

Hematocrit Predicts Long-Term Mortality in a Nonlinear and Sex-Specific Manner in Hypertensive Adults

article

Heritability analyses show visit-to-visit blood pressure variability reflects different pathological phenotypes in younger and older adults: evidence from UK twins

artículo científico publicado en 2013

Hypertension Pharmacogenomics

Hypertension and genome-wide association studies: combining high fidelity phenotyping and hypercontrols

article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Impact of comprehensive cardiovascular risk reduction programme on risk factor clustering associated with elevated blood pressure in an Indian industrial population.

artículo científico publicado en 2012

Impact of major depression on cardiovascular outcomes for individuals with hypertension: prospective survival analysis in UK Biobank

artículo científico publicado en 2019

Implications of discoveries from genome-wide association studies in current cardiovascular practice.

artículo científico publicado en 2011

Insulin resistance: Genetic associations with depression and cognition in population based cohorts

scientific article published on 06 April 2019

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

artículo científico publicado el 2 de agosto de 2016

KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern

artículo científico publicado en 2019

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

artículo científico publicado en 2012

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

artículo científico publicado en 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Loci influencing blood pressure identified using a cardiovascular gene-centric array

artículo científico publicado en 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

artículo científico publicado en 2013

Long-term and ultra long-term blood pressure variability during follow-up and mortality in 14,522 patients with hypertension

artículo científico publicado en 2013

Longitudinal Blood Pressure Control, Long-Term Mortality, and Predictive Utility of Serum Liver Enzymes and Bilirubin in Hypertensive Patients

artículo científico publicado en 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

artículo científico publicado en 2015

Machine learning integration of multimodal data identifies key features of blood pressure regulation

artículo científico publicado en 2022

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

artículo científico publicado en 2015

May Measurement Month 2017: an analysis of blood pressure screening results from the United Kingdom and the Republic of Ireland-Europe

artículo científico publicado en 2019

May Measurement Month 2018: an analysis of blood pressure screening results from the UK and the Republic of Ireland

scientific article published on 28 August 2020

Mendelian randomization of blood lipids for coronary heart disease

artículo científico publicado en 2014

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

artículo científico publicado en 2015

Metabolomic profiling identifies novel associations with Electrolyte and Acid-Base Homeostatic patterns

artículo científico publicado en 2019

Metabolomic study of carotid-femoral pulse-wave velocity in women

artículo científico publicado en 2015

Methods to Assess Genetic Risk Prediction.

artículo científico publicado en 2017

Molecular genetic contributions to socioeconomic status and intelligence.

artículo científico publicado en 2014

Molecular pathways associated with blood pressure and hexadecanedioate levels

artículo científico publicado en 2017

Monotherapy With Major Antihypertensive Drug Classes and Risk of Hospital Admissions for Mood Disorders

artículo científico publicado en 2016

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ethnic genome-wide association study for atrial fibrillation

article

NEDD4L in essential hypertension.

artículo científico publicado en 2014

Necessity of Preventing Cardiovascular Disease by Smoke-Free Policies

artículo científico publicado en 2018

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes

artículo científico publicado en 2016

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Urinary Peptidomic Classifier Predicts Incident Heart Failure

artículo científico publicado en 2017

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention

scientific article published on 17 August 2009

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

artículo científico publicado en 2016

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

artículo científico publicado en 2015

Pharmacodynamic Pharmacogenomics

Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes

artículo científico publicado en 2013

Pharmacogenomics and Stratified Medicine

Pharmacokinetic Pharmacogenomics

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting

artículo científico

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

artículo científico publicado en 2015

Prognostic Models Derived in PARADIGM-HF and Validated in ATMOSPHERE and the Swedish Heart Failure Registry to Predict Mortality and Morbidity in Chronic Heart Failure

scientific article published on 29 January 2020

Prospects for genetic risk prediction in hypertension

artículo científico publicado en 2013

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

QTc and Sudden Cardiac Death

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial.

artículo científico publicado en 2018

Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study

artículo científico publicado en 2018

Rationale and design of the Medical Research Council's Precision Medicine with Zibotentan in Microvascular Angina (PRIZE) trial

scientific article published on 17 July 2020

Recent Findings in the Genetics of Blood Pressure: How to Apply in Practice or Is a Moonshot Required?

artículo científico publicado en 2018

Response to Effect of Serum Chloride on Mortality in Hypertensive Patients

artículo científico publicado en 2014

Resting heart rate and outcomes in patients with cardiovascular disease: where do we currently stand?

artículo científico publicado en 2013

Resting heart rate pattern during follow-up and mortality in hypertensive patients

artículo científico publicado en 2009

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy

scientific journal article

Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study

scientific article published on 01 December 2018

Risks of socioeconomic deprivation on mortality in hypertensive patients

artículo científico publicado en 2009

Salt stress in the renal tubules is linked to TAL-specific expression of uromodulin and an upregulation of heat shock genes

article

Serum chloride is an independent predictor of mortality in hypertensive patients

artículo científico publicado en 2013

Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease

artículo científico publicado en 2015

Serum uric acid level, longitudinal blood pressure, renal function, and long-term mortality in treated hypertensive patients

artículo científico publicado en 2013

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression

artículo científico publicado en 2016

Should diabetes be considered a coronary heart disease risk equivalent?: results from 25 years of follow-up in the Renfrew and Paisley survey

artículo científico publicado en 2005

Simple multi-trait analysis identifies novel loci associated with growth and obesity measures

scholarly article published 8 July 2015

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

artículo científico publicado en 2015

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

artículo científico publicado en 2014

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

artículo científico publicado en 2015

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

artículo científico publicado en 2015

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

The Pharmacogenomics of Anti-Hypertensive Therapy

artículo científico publicado en 2010

The Y Chromosome Effect on Blood Pressure in Two European Populations

article

The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study

The genetic determination of left ventricular mass in healthy adults

artículo científico publicado en 2003

The genetics of cardiovascular disease

artículo científico publicado en 2008

The hidden hand of chloride in hypertension

artículo científico publicado en 2015

The relationship between antihypertensive medications and mood disorders: analysis of linked healthcare data for 1.8 million patients

scientific article published on 24 January 2020

Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.

artículo científico publicado en 2017

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Unsupervised Discovery and Comparison of Structural Families Across Multiple Samples in Untargeted Metabolomics

artículo científico publicado en 2017

Urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation

scientific article published on 05 July 2016

Urine Metabolomics in Hypertension Research

artículo científico publicado en 2017

Uromodulin, an emerging novel pathway for blood pressure regulation and hypertension

artículo científico publicado en 2014

Validation of uromodulin as a candidate gene for human essential hypertension

artículo científico publicado en 2013

Variants associated with expression have sex-differential effects on lung function

artículo científico publicado en 2020

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

artículo científico publicado en 2017

Variation at the beta-1 adrenoceptor gene locus affects left ventricular mass in renal failure.

artículo científico publicado en 2002

Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid

artículo científico publicado en 2014