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Lista de obras de Soumya Raychaudhuri

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping

artículo científico publicado en 2016

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases

artículo científico publicado en 2016

A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity

artículo científico publicado en 2014

A positively selected FBN1 missense variant reduces height in Peruvian individuals

scientific article published on 13 May 2020

A rare coding allele in IFIH1 is protective for psoriatic arthritis

artículo científico publicado en 2017

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.

artículo científico publicado en 2011

A role for noncoding variation in schizophrenia

artículo científico publicado en 2014

A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.

artículo científico publicado en 2013

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

artículo científico publicado en 2015

Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis

scientific article published on 28 November 2019

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

artículo científico publicado en 2020

An argument for early genomic sequencing in atypical cases: a WISP3 variant leads to diagnosis of progressive pseudorheumatoid arthropathy of childhood.

artículo científico publicado en 2015

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery

artículo científico publicado en 2018

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

artículo científico publicado en 2014

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

artículo científico publicado en 2016

Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells

artículo científico publicado en 2013

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response

artículo científico publicado en 2015

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for and CD39

article

Association of valine and leucine at HLA-DRB1 position 11 with radiographic progression in rheumatoid arthritis, independent of the shared epitope alleles but not independent of anti-citrullinated protein antibodies.

artículo científico publicado en 2015

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

artículo científico publicado en 2016

Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes

artículo científico publicado en 2022

Author Correction: Perspectives on ENCODE

artículo científico publicado en 2022

Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

scientific article published on 01 November 2019

Autoimmune diseases - connecting risk alleles with molecular traits of the immune system

artículo científico publicado en 2016

Autoimmunity: insights from human genomics

artículo científico publicado en 2012

Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

article

Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.

artículo científico publicado en 2016

Common genetic variants modulate pathogen-sensing responses in human dendritic cells

artículo científico publicado en 2014

Common risk alleles for inflammatory diseases are targets of recent positive selection

artículo científico publicado en 2013

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

scientific article published on 14 September 2008

Complex Diseases, Complex Genes

artículo científico publicado en 2009

Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

scientific article published on August 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

artículo científico publicado en 2019

Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial

artículo científico publicado en 2018

Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.

artículo científico publicado en 2015

Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease.

artículo científico publicado en 2015

Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress

scientific article published on 05 March 2020

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype

artículo científico publicado en 2019

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype

artículo científico publicado en 2019

Distinct fibroblast subsets drive inflammation and damage in arthritis

scientific article published on 29 May 2019

Do Genetic Susceptibility Variants Associate with Disease Severity in Early Active Rheumatoid Arthritis?

artículo científico publicado en 2015

Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

scientific article published on 21 August 2019

Efficient and precise single-cell reference atlas mapping with Symphony

artículo científico

Familial aggregation of arthritis-related diseases in seropositive and seronegative rheumatoid arthritis: a register-based case-control study in Sweden

artículo científico publicado en 2014

Fast, sensitive and accurate integration of single-cell data with Harmony

artículo científico publicado en 2019

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease

artículo científico publicado en 2015

Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.

artículo científico publicado en 2014

Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes

artículo científico publicado en 2018

Fine-mapping identifies causal variants for RA and T1D in DNASE1L3, SIRPG, MEG3, TNFAIP3 and CD28/CTLA4 loci

Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases

artículo científico publicado en 2016

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

artículo científico publicado en 2012

Functional genomics of stromal cells in chronic inflammatory diseases.

artículo científico publicado en 2017

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

artículo científico publicado en 2018

Genes with High Network Connectivity Are Enriched for Disease Heritability

scientific article published on 01 May 2019

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

artículo científico publicado en 2017

Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population.

artículo científico publicado en 2017

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

artículo científico publicado en 2013

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.

artículo científico publicado en 2016

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

artículo científico publicado en 2009

Genetic variants in the complement system predisposing to age-related macular degeneration: a review

artículo científico publicado en 2014

Genetics and epigenetics of rheumatoid arthritis

artículo científico publicado en 2013

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Genome-Wide Association Studies Suggest Limited Immune Gene Enrichment in Schizophrenia Compared to 5 Autoimmune Diseases

scientific article published on 30 May 2016

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

artículo científico publicado en 2013

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

artículo científico publicado en 2010

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)

artículo científico publicado en 2010

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

artículo científico publicado en 2010

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

HBEGF macrophages in rheumatoid arthritis induce fibroblast invasiveness

artículo científico publicado en 2019

HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues.

artículo científico publicado en 2014

Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes

scientific journal article

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

artículo científico publicado en 2018

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

artículo científico publicado en 2012

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.

artículo científico publicado en 2014

Higher native Peruvian genetic ancestry proportion is associated with tuberculosis progression risk

artículo científico publicado en 2022

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

artículo científico publicado en 2012

How COVID-19 is changing rheumatology clinical practice

artículo científico publicado en 2020

Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway

artículo científico publicado en 2013

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation

scientific article published on 05 August 2020

IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

artículo científico publicado en 2021

IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors

artículo científico publicado en 2019

Immune cell profiling to guide therapeutic decisions in rheumatic diseases

artículo científico publicado en 2015

Immunoprofiling comes of age

artículo científico publicado en 2019

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements

artículo científico publicado en 2020

Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitis

artículo científico publicado en 2018

Imputing amino acid polymorphisms in human leukocyte antigens

artículo científico publicado en 2013

Integrating Autoimmune Risk Loci with Gene-Expression Data Identifies Specific Pathogenic Immune Cell Subsets

article published in 2011

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

artículo científico publicado en 2014

Interactions Between Genome-Wide Genetic Factors and Smoking Influencing Risk of Systemic Lupus Erythematosus

scientific article published on 23 September 2020

Interactions between amino acid-defined major histocompatibility complex class II variants and smoking in seropositive rheumatoid arthritis

artículo científico publicado en 2015

Interrogating the major histocompatibility complex with high-throughput genomics

artículo científico publicado en 2012

Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study

artículo científico publicado en 2017

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

artículo científico publicado en 2016

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

artículo científico publicado en 2020

Leveraging blood and tissue CD4+ T cell heterogeneity at the single cell level to identify mechanisms of disease in rheumatoid arthritis.

artículo científico publicado en 2017

Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis

artículo científico publicado en 2010

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study

artículo científico publicado en 2015

Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions

artículo científico publicado en 2019

Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture

scientific journal article

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

artículo científico publicado en 2009

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

scientific journal article

Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue

artículo científico publicado en 2018

Mixed-effects association of single cells identifies an expanded effector CD4 T cell subset in rheumatoid arthritis

artículo científico publicado en 2018

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

artículo científico publicado en 2017

Multimodal single-cell approaches shed light on T cell heterogeneity

artículo científico publicado en 2019

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

artículo científico publicado en 2015

Notch signalling drives synovial fibroblast identity and arthritis pathology

artículo científico publicado en 2020

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

scientific article published on 10 June 2022

Partitioning heritability by functional annotation using genome-wide association summary statistics

artículo científico publicado en 2015

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

artículo científico publicado en 2014

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

artículo científico publicado en 2017

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.

artículo científico publicado en 2017

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

artículo científico publicado en 2014

Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data

artículo científico publicado en 2022

Practical aspects of imputation-driven meta-analysis of genome-wide association studies

artículo científico publicado en 2008

Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations

artículo científico publicado en 2014

Proceedings of the 2021 GRAPPA-Collaborative Research Network (CRN) Meeting

artículo científico publicado en 2022

Publisher Correction: The immune cell landscape in kidneys of patients with lupus nephritis

artículo científico publicado en 2019

Quantifying missing heritability at known GWAS loci

artículo científico publicado en 2013

Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration

artículo científico publicado en 2015

Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders

artículo científico publicado en 2013

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis

artículo científico publicado en 2012

Recent Advances in Defining the Genetic Basis of Rheumatoid Arthritis.

artículo científico publicado en 2016

Recent advances in the genetics of rheumatoid arthritis

artículo científico publicado en 2010

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells

artículo científico publicado en 2014

Review: Genetics and the Classification of Arthritis in Adults and Children

artículo científico publicado en 2017

Rheumatoid Factor Is Associated With the Distribution of Hand Joint Destruction in Rheumatoid Arthritis

artículo científico publicado en 2015

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

artículo científico publicado en 2010

Rheumatoid arthritis. Evidence for a genetic component to disease severity in RA

artículo científico publicado en 2012

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

artículo científico publicado en 2014

Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08

scientific journal article

SNPsea: an algorithm to identify cell types, tissues and pathways affected by risk loci

artículo científico publicado en 2014

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal

artículo científico publicado en 2020

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

artículo científico publicado en 2015

The PRL -1149 G/T polymorphism and rheumatoid arthritis susceptibility

artículo científico publicado en 2009

The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype

scientific article published on 08 October 2018

The immune cell landscape in kidneys of patients with lupus nephritis

artículo científico publicado en 2019

The landscape of somatic copy-number alteration across human cancers

artículo científico publicado en 2010

The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)

artículo científico publicado en 2011

Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9

artículo científico publicado en 2011

Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis.

artículo científico publicado en 2017

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

artículo científico publicado en 2019

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12

artículo científico publicado en 2012

Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases.

artículo científico publicado en 2013

Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis

artículo científico publicado en 2020

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

artículo científico publicado en 2015

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