Lista de obras - Bo Isomaa - Dominio Público Uruguay

35th Annual Meeting of the European Association for the Study of Diabetes

artículo científico

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A central role for GRB10 in regulation of islet function in man.

artículo científico publicado en 2014

A common variant upstream of the PAX6 gene influences islet function in man.

artículo científico publicado en 2011

A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study

artículo científico publicado en 2010

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

artículo científico publicado en 2009

Adolescents at Risk for MODY3 Diabetes Prefer Genetic Testing Before Adulthood

article published in 2007

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

article

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

artículo científico publicado en 2009

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study

artículo científico publicado en 2011

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

artículo científico publicado en 2011

Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect

scientific article published on February 1997

Chronic complications in patients with slowly progressing autoimmune type 1 diabetes (LADA).

artículo científico publicado en 1999

Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies

artículo científico publicado en 1999

Clinical risk factors, DNA variants, and the development of type 2 diabetes

artículo científico publicado en 2008

Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time

artículo científico publicado en 2011

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

artículo científico publicado en 2008

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

artículo científico publicado en 2008

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

artículo científico publicado en 2008

Complex Relationship Between Blood Pressure and Mortality in Type 2 Diabetic Patients

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

artículo científico publicado en 2006

Consequences of a family history of type 1 and type 2 diabetes on the phenotype of patients with type 2 diabetes

artículo científico publicado en 2000

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study

artículo científico publicado en 2011

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Effect of a common variant of the PCSK2 gene on reduced insulin secretion

artículo científico publicado en 2012

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

artículo científico publicado en 2013

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband

artículo científico publicado en 2003

Family history of Type 1 diabetes affects insulin secretion in patients with 'Type 2' diabetes

artículo científico publicado en 2013

GAD antibody positivity predicts type 2 diabetes in an adult population

artículo científico publicado en 2009

Genetic evidence of assortative mating in humans

article

Genetic testing for maturity onset diabetes of the young: uptake, attitudes and comparison with hereditary non-polyposis colorectal cancer.

artículo científico publicado en 2005

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins

artículo científico publicado en 2009

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts

artículo científico publicado en 2009

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

artículo científico publicado en 2014

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

artículo científico publicado en 2017

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

artículo científico publicado en 2007

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

HAPT2D: High accuracy of prediction of T2D with a model combining basic and advanced data depending on availability

artículo científico publicado en 2018

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

article by Peter Almgren et al published 9 August 2011 in Diabetologia

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of ten loci associated with height highlights new biological pathways in human growth

artículo científico publicado en 2008

Improved prandial glucose control with lower risk of hypoglycemia with nateglinide than with glibenclamide in patients with maturity-onset diabetes of the young type 3.

artículo científico publicado en 2006

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

artículo científico publicado en 2016

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study

artículo científico publicado en 2000

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

artículo científico publicado en 2010

Link between GIP and osteopontin in adipose tissue and insulin resistance

artículo científico publicado en 2013

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

artículo científico publicado en 2014

MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

artículo científico publicado en 1998

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects

artículo científico publicado en 1996

Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts

artículo científico publicado en 2014

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

artículo científico publicado en 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Pleiotropic effects of GIP on islet function involve osteopontin

artículo científico publicado en 2011

Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion

artículo científico publicado en 2007

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes

artículo científico publicado en 2005

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study

artículo científico publicado en 2014

Stressful life events and the metabolic syndrome: the prevalence, prediction and prevention of diabetes (PPP)-Botnia Study

artículo científico publicado en 2009

Subjective sleep complaints are associated with insulin resistance in individuals without diabetes: the PPP-Botnia Study

artículo científico publicado en 2012

Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia

artículo científico publicado en 2012

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts

artículo científico publicado en 2007

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes

artículo científico publicado en 2012

The metabolic syndrome influences the risk of chronic complications in patients with type II diabetes

artículo científico publicado en 2001

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo

artículo científico publicado en 2011

Update on Current Care Guideline. Diabetes

artículo científico publicado en 2016

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality

artículo científico publicado en 2007

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

artículo

Lista de obras de Bo Isomaa

35th Annual Meeting of the European Association for the Study of Diabetes

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

A central role for GRB10 in regulation of islet function in man.

A common variant upstream of the PAX6 gene influences islet function in man.

A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study

A genome-wide association search for type 2 diabetes genes in African Americans

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

Adolescents at Risk for MODY3 Diabetes Prefer Genetic Testing Before Adulthood

Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies

Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study

Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect

Chronic complications in patients with slowly progressing autoimmune type 1 diabetes (LADA).

Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies

Clinical risk factors, DNA variants, and the development of type 2 diabetes

Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

Complex Relationship Between Blood Pressure and Mortality in Type 2 Diabetic Patients

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

Consequences of a family history of type 1 and type 2 diabetes on the phenotype of patients with type 2 diabetes

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

Effect of a common variant of the PCSK2 gene on reduced insulin secretion

Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband

Family history of Type 1 diabetes affects insulin secretion in patients with 'Type 2' diabetes

GAD antibody positivity predicts type 2 diabetes in an adult population

Genetic evidence of assortative mating in humans

Genetic testing for maturity onset diabetes of the young: uptake, attitudes and comparison with hereditary non-polyposis colorectal cancer.

Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

HAPT2D: High accuracy of prediction of T2D with a model combining basic and advanced data depending on availability

Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Identification of ten loci associated with height highlights new biological pathways in human growth

Improved prandial glucose control with lower risk of hypoglycemia with nateglinide than with glibenclamide in patients with maturity-onset diabetes of the young type 3.

Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

Link between GIP and osteopontin in adipose tissue and insulin resistance

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects

Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

Pleiotropic effects of GIP on islet function involve osteopontin

Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study