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Lista de obras de Samuli Ripatti

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

artículo científico publicado en 2015

A P3G generic access agreement for population genomic studies

artículo científico publicado en 2013

A common variant near the KCNJ2 gene is associated with T-peak to T-end interval

artículo científico publicado en 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A genome-wide analysis of populations from European Russia reveals a new pole of genetic diversity in northern Europe

artículo científico publicado en 2013

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

artículo científico publicado en 2012

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

artículo científico publicado en 2010

A random change point model for assessing variability in repeated measures of cognitive function

artículo científico publicado en 2008

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

artículo científico publicado en 2012

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

artículo científico publicado en 2015

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Allele-specific regulation of DISC1 expression by miR-135b-5p

artículo científico publicado en 2013

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

artículo científico publicado en 2020

An immune response network associated with blood lipid levels

artículo científico publicado en 2010

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits

artículo científico publicado en 2012

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

artículo científico publicado en 2014

Association of variants in DISC1 with psychosis-related traits in a large population cohort

artículo científico publicado en 2009

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Associations of nicotine intake measures with CHRN genes in Finnish smokers

artículo científico publicado en 2011

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

artículo científico publicado en 2014

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls

artículo científico publicado en 2010

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation

artículo científico publicado en 2014

Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus

artículo científico publicado en 2002

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Conditional models accounting for regression to the mean in observational multi-wave panel studies on alcohol consumption

artículo científico publicado en 2007

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

scientific article published on 04 August 2013

Determinants of the progression in lumbar degeneration: a 5-year follow-up study of adult male monozygotic twins

artículo científico publicado en 2006

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Distinct variants at LIN28B influence growth in height from birth to adulthood

artículo científico publicado en 2010

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Does expecting more pain make it more intense? Factors associated with the first week pain trajectories after breast cancer surgery

artículo científico publicado en 2017

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

artículo científico publicado en 2016

Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer

artículo científico publicado en 2013

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

artículo científico publicado en 2011

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Estimation of multivariate frailty models using penalized partial likelihood

artículo científico publicado en 2000

European lactase persistence genotype shows evidence of association with increase in body mass index

artículo científico publicado en 2009

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

artículo científico publicado en 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

FINEMAP: efficient variable selection using summary data from genome-wide association studies

artículo científico publicado en 2016

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Fitting exponential family mixed models

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis

artículo científico publicado en 2009

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

artículo científico publicado en 2010

From genetic discovery to future personalized health research

artículo científico publicado en 2012

Further Evidence For the Role ofENPP1in Obesity: Association With Morbid Obesity in Finns

article

GENESTAT: an information portal for design and analysis of genetic association studies

artículo científico publicado en 2009

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

artículo científico publicado en 2013

Gender differences in genetic risk profiles for cardiovascular disease

artículo científico publicado en 2008

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population

artículo científico publicado en 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of circulating lipid levels

artículo científico publicado en 2011

Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis

artículo científico publicado en 2009

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

artículo científico publicado en 2017

Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--

artículo científico publicado en 2012

Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease

artículo científico publicado en 2013

Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2011

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

artículo científico publicado en 2010

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genome-Wide Analysis of Evolutionary Markers of Human Influenza A(H1N1)pdm09 and A(H3N2) Viruses May Guide Selection of Vaccine Strain Candidates

artículo científico publicado en 2015

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-Wide Meta-Analysis of Sciatica in Finnish Population

artículo científico publicado en 2016

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

artículo científico publicado en 2016

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

artículo científico publicado en 2009

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

artículo científico publicado en 2013

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

artículo científico publicado en 2022

Genome-wide association study identifies 48 common genetic variants associated with handedness

artículo científico publicado en 2020

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

artículo científico publicado en 2019

Genome-wide association study identifies five loci associated with lung function

artículo científico publicado en 2010

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

artículo científico publicado en 2014

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

artículo científico publicado en 2016

Genome-wide time-to-event analysis on smoking progression stages in a family-based study

artículo científico publicado en 2016

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

artículo científico publicado en 2013

Genomic prediction of coronary heart disease

artículo científico publicado en 2016

Geographical structure and differential natural selection among North European populations

scientific article published on 05 March 2009

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

artículo científico publicado en 2016

Hierarchical Bayesian model for rare variant association analysis integrating genotype uncertainty in human sequence data

artículo científico publicado en 2014

High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms

artículo científico publicado en 2014

High-resolution population-specific recombination rates and their effect on phasing and genotype imputation

artículo científico publicado en 2020

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of seven loci affecting mean telomere length and their association with disease

artículo científico publicado en 2013

Impact of common variation in bone-related genes on type 2 diabetes and related traits

artículo científico publicado en 2012

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

artículo científico publicado en 2012

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Lipidome‐ and Genome‐Wide Study to Understand Sex Differences in Circulatory Lipids

artículo científico publicado en 2022

Maximum likelihood inference for multivariate frailty models using an automated Monte Carlo EM algorithm.

artículo científico publicado en 2002

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

artículo científico publicado en 2016

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

artículo científico publicado en 2017

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

artículo científico publicado en 2016

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Metabolic signatures of insulin resistance in 7,098 young adults

artículo científico publicado en 2012

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

artículo científico publicado en 2015

Metabonomic, transcriptomic, and genomic variation of a population cohort

artículo científico publicado en 2010

Missing value imputation in longitudinal measures of alcohol consumption

artículo científico publicado en 2011

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

NordicDB: a Nordic pool and portal for genome-wide control data

artículo científico publicado en 2010

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis

artículo científico publicado en 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans

artículo científico publicado en 2013

Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs

artículo científico publicado en 2015

Phenotype mining in CNV carriers from a population cohort

artículo científico publicado en 2011

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

scientific article published on 07 April 2020

Postprandial metabolism of apolipoproteins B48, B100, C-III and E in humans with APOC3 loss-of-function mutations

artículo científico publicado en 2022

Psychiatric comorbidity in couples: a longitudinal study of 202,959 married and cohabiting individuals.

artículo científico publicado en 2010

Pubertal timing and growth influences cardiometabolic risk factors in adult males and females

artículo científico publicado en 2012

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

artículo científico publicado en 2016

Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci

scientific article published on 30 January 2014

Regularized Machine Learning in the Genetic Prediction of Complex Traits

artículo científico publicado en 2014

SNPs and coronary heart disease – Authors' reply

artículo científico publicado en 2011

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

artículo científico publicado en 2010

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

Targeted resequencing of the pericentromere of chromosome 2 linked to constitutional delay of growth and puberty

artículo científico publicado en 2015

The Contribution of GWAS Loci in Familial Dyslipidemias

artículo científico publicado en 2016

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

artículo científico publicado en 2014

The genetic structure of the Swedish population

artículo científico publicado en 2011

The genome-wide patterns of variation expose significant substructure in a founder population

artículo científico publicado en 2008

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The influence of mortality on twin models of change: addressing missingness through multiple imputation

artículo científico publicado en 2003

The molecular genetic architecture of self-employment

artículo científico publicado en 2013

The power of genetic diversity in genome-wide association studies of lipids

The rocky road to personalized medicine: computational and statistical challenges

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The transcriptional landscape of age in human peripheral blood

artículo científico publicado en 2015

Three-state frailty model for age at onset of dementia and death in Swedish twins

artículo científico publicado en 2003

Towards a molecular systems model of coronary artery disease

artículo científico publicado en 2014

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

artículo científico publicado en 2016

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes

artículo científico publicado en 2010

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

artículo científico publicado en 2016

Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

artículo científico publicado en 2017

Work-related exhaustion and telomere length: a population-based study

artículo científico publicado en 2012

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

artículo científico publicado en 2016

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