Lista de obras - Terho Lehtimäki - Dominio Público Uruguay

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

artículo científico publicado en 2017

5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

artículo científico publicado en 2009

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

artículo científico publicado en 2015

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A Longitudinal Multilevel Study of the "Social" Genotype and Diversity of the Phenotype

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects

artículo científico publicado en 2005

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study

artículo científico publicado en 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A diagnosis of the metabolic syndrome in youth that resolves by adult life is associated with a normalization of high carotid intima-media thickness and type 2 diabetes mellitus risk: the Bogalusa heart and cardiovascular risk in young Finns studies

artículo científico publicado en 2012

A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.

artículo científico publicado en 2011

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

artículo científico publicado en 2015

A genome-wide association meta-analysis identifies new childhood obesity loci

artículo científico publicado en 2012

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

artículo científico publicado en 2012

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

scientific article published on 12 July 2016

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

artículo científico publicado en 2017

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2012

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

artículo científico publicado en 2015

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2011

A meta-analysis of genome-wide association studies identifies multiple longevity genes

scientific article published on 14 August 2019

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

artículo científico publicado en 2012

A metabolic view on menopause and ageing

artículo científico publicado en 2014

A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserve

artículo científico publicado en 2007

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

artículo científico publicado en 2014

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A randomized trial of early detection of clinically significant prostate cancer (ProScreen): study design and rationale

artículo científico publicado en 2017

A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle

artículo científico publicado en 2006

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

ACE polymorphism and response to electroconvulsive therapy in major depression

artículo científico publicado en 2009

ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study

artículo científico publicado en 2009

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study

artículo científico publicado en 2009

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

scientific article published on 01 November 2019

Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions

artículo científico publicado en 2014

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients

artículo científico publicado en 2003

Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study

artículo científico publicado en 2015

Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study

artículo científico publicado en 2010

Adhesion Molecules in Multiple Sclerosis

artículo científico publicado en 2000

Adhesion molecules in multiple sclerosis: relation to subtypes of disease and methylprednisolone therapy

artículo científico publicado en 2000

Adolescence Risk Factors Are Predictive of Coronary Artery Calcification at Middle Age

scholarly article by Olli Hartiala et al published October 2012 in Journal of the American College of Cardiology

Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2008

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

artículo científico publicado en 2021

Adverse childhood environment and self-reported sleep in adulthood: The Young Finns Study

scientific article published on 20 June 2019

Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting

artículo científico publicado en 2007

Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

artículo científico publicado en 2006

Age-dependent association of gut bacteria with coronary atherosclerosis: Tampere Sudden Death Study

scientific article published on 22 August 2019

Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction--Helsinki Sudden Death Study

artículo científico publicado en 2012

Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing

artículo científico publicado en 2011

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

artículo científico publicado en 2014

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

artículo científico publicado en 2017

Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis

article

Analysis of free, mono- and diacetylated polyamines from human urine by LC-MS/MS.

artículo científico publicado en 2013

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis

artículo científico publicado en 2005

Aortic sinus diameter in middle age is associated with body size in young adulthood

artículo científico publicado en 2017

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study

artículo científico publicado en 2020

Apolipoprotein A-I/C-III/A-IV SstI and Apolipoprotein B XbaI Polymorphisms Do not Affect Early Functional and Structural Changes in Atherosclerosis

artículo científico publicado en 2007

Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2005

Apolipoprotein B is related to arterial pulse wave velocity in young adults: The Cardiovascular Risk in Young Finns Study

scholarly article by Teemu Koivistoinen et al published January 2011 in Atherosclerosis

Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2011

Apolipoprotein E gene polymorphism, hypercholesterolemia and glomerular filtration rate in type 2 diabetic subjects: a 9-year follow-up study.

artículo científico publicado en 2003

Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians

artículo científico publicado en 2006

Apolipoprotein E polymorphism is associated with age of onset in schizophrenia

artículo científico publicado en 2004

Apoptosis-related molecules in blood in multiple sclerosis

artículo científico publicado en 2008

Arterial pulse wave velocity in relation to carotid intima-media thickness, brachial flow-mediated dilation and carotid artery distensibility: The Cardiovascular Risk in Young Finns Study and the Health 2000 Survey

article

Arterial tension time reflects subclinical atherosclerosis, arterial stiffness and stroke volume

artículo científico publicado en 2011

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

artículo científico publicado en 2014

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

artículo científico

Association analysis of allelic variants of USF1 in coronary atherosclerosis

artículo científico publicado en 2008

Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach

artículo científico publicado en 2007

Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia

scientific article published on 14 September 2006

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

artículo científico publicado en 2019

Association of EGF polymorphism with schizophrenia in Finnish men.

artículo científico publicado en 2004

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

artículo científico publicado en 2020

Association of Known Loci With Lipid Levels Among Children and Prediction of Dyslipidemia in Adults

Association of Neuropeptide Y Polymorphism With the Occurrence of Type 1 and Type 2 Alcoholism ⬇️

artículo científico publicado el 1 de octubre de 2001

Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake — The Cardiovascular Risk in Young Finns Study

scholarly article by Sanna Tolonen et al published May 2011 in Bone

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

artículo científico publicado en 2018

Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.

artículo científico publicado en 2018

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

scientific article published on 01 August 2019

Association of high sensitive C-reactive protein with apolipoprotein E polymorphism in children and young adults: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2008

Association of lifetime blood pressure with adulthood exercise blood pressure response: the cardiovascular risk in young Finns study

scientific article published on 05 January 2021

Association of mannan-binding lectin deficiency with venous bypass graft occlusions in patients with coronary heart disease

artículo científico publicado en 2002

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Association of neuroimmune guidance cue netrin-1 and its chemorepulsive receptor UNC5B with atherosclerotic plaque expression signatures and stability in human(s): Tampere Vascular Study (TVS).

artículo científico publicado en 2013

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study

artículo científico publicado en 2004

Association of physical activity in childhood and early adulthood with carotid artery elasticity 21 years later: the cardiovascular risk in Young Finns Study

artículo científico publicado en 2014

Association of resting heart rate with cardiovascular function: a cross-sectional study in 522 Finnish subjects

artículo científico publicado en 2013

Association of serum MMP-9 with autoantibodies against oxidized LDL ⬇️

artículo científico publicado el 1 de enero de 2002

Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men.

artículo científico publicado en 2006

Association of the apolipoprotein E gene, its promoter polymorphisms and haplotypes with depressive symptoms. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2008

Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events

Association of thyrotropin with arterial pulse wave velocity in young adults: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2014

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study

scholarly article by Mervi Oikonen et al published August 2012 in Atherosclerosis

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

artículo científico publicado en 2016

Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study

artículo científico publicado en 2008

Asymmetric dimethylarginine and hemodynamic regulation in middle-aged men

Asymmetrical dimethylarginine (ADMA) and risk of acute coronary events. Does statin treatment influence plasma ADMA levels?

artículo científico publicado en 2003

Atrioventricular conduction and cardiovascular mortality: Assessment of recovery PR interval is superior to pre-exercise measurement

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2009

BDNF and NRG1 polymorphisms and temperament in selective serotonin reuptake inhibitor-treated patients with major depression

artículo científico publicado en 2018

BDNF polymorphism rs11030101 is associated with the efficacy of electroconvulsive therapy in treatment-resistant depression

artículo científico publicado en 2013

BMI Trajectories Associated With Resolution of Elevated Youth BMI and Incident Adult Obesity

artículo científico publicado en 2017

Bacterial DNA findings in ruptured and unruptured intracranial aneurysms

artículo científico publicado en 2016

Bacterial DNA signatures in carotid atherosclerosis represent both commensals and pathogens of skin origin

artículo científico publicado en 2013

Bacterial signatures in thrombus aspirates of patients with lower limb arterial and venous thrombosis

artículo científico

Bacterial signatures in thrombus aspirates of patients with myocardial infarction

artículo científico publicado en 2013

Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies

artículo científico publicado en 2017

Beyond LDL-C lowering: distinct molecular sphingolipids are good indicators of proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency

artículo científico publicado en 2013

Bidirectional pathways between psychosocial risk factors and paranoid ideation in a general nonclinical population

artículo científico publicado en 2020

Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients

scientific article published on 01 November 2018

Birth weight and adult income: An examination of mediation through adult height and body mass

article by Jaakko Pehkonen et al published 11 July 2021 in Health Economics

Birth weight, adult weight, and cardiovascular biomarkers: Evidence from the Cardiovascular Young Finns Study

artículo científico publicado en 2022

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study

artículo científico publicado en 2016

Blood leukocyte count is a risk factor for intima-media thickening and subclinical carotid atherosclerosis in middle-aged men.

artículo científico publicado en 2005

Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study

artículo científico publicado en 2014

Blood pathway analyses reveal differences between prediabetic subjects with or without dyslipidaemia. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2017

Both youth and long-term vitamin D status is associated with risk of type 2 diabetes mellitus in adulthood: a cohort study

artículo científico publicado en 2017

Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder

artículo científico publicado en 2007

Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults

artículo científico publicado en 2012

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

artículo científico publicado en 2022

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

CVD risk factors and surrogate markers - Urban-rural differences

scientific article published on 29 August 2019

CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine

artículo científico publicado en 2014

Carbonic anhydrases II and XII are up-regulated in osteoclast-like cells in advanced human atherosclerotic plaques-Tampere Vascular Study

artículo científico publicado en 2010

Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2018

Cardiometabolic and Inflammatory Biomarkers as Mediators Between Educational Attainment and Functioning at the Age of 90 Years

artículo científico publicado en 2015

Cardiorespiratory Fitness and Risk of Fatty Liver: The Young Finns Study

artículo científico publicado en 2017

Cardiorespiratory fitness and heart rate recovery predict sudden cardiac death independent of ejection fraction

artículo científico publicado en 2019

Cardiovascular Health Trajectories From Childhood Through Middle Age and Their Association With Subclinical Atherosclerosis

scientific article published on 11 March 2020

Cardiovascular Risk Factors From Childhood and Midlife Cognitive Performance: The Young Finns Study

artículo científico publicado en 2017

Cardiovascular risk factors in 2011 and secular trends since 2007: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2014

Cardiovascular risk scores in the prediction of subclinical atherosclerosis in young adults: evidence from the cardiovascular risk in a young Finns study

artículo científico publicado en 2010

Carotid artery intima-media thickness in children with type 1 diabetes

artículo científico publicado en 2002

Carotid atherosclerosis in chronic renal failure-the central role of increased plaque burden

scientific article published on 01 December 2003

Catechol-O-methyltransferase (COMT) polymorphisms predict treatment response in electroconvulsive therapy

artículo científico publicado en 2007

Catechol-O-methyltransferase and monoamine oxidase A genotypes and drug response to conventional neuroleptics in schizophrenia

artículo científico publicado en 2003

Catechol-O-methyltransferase val108/158met genotype and response to antipsychotic medication in schizophrenia

scientific article published on 01 June 2007

Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder

artículo científico publicado en 2010

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

artículo científico publicado en 2013

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis

Childbearing, child-rearing, cardiovascular risk factors, and progression of carotid intima-media thickness: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2010

Childhood Exposure to Passive Smoking and Bone Health in Adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 01 June 2019

Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic Risk

artículo científico publicado en 2016

Childhood Serum Fatty Acid Quality Is Associated with Adult Carotid Artery Intima Media Thickness in Women but Not in Men

Childhood Socioeconomic Disadvantage and Risk of Fatty Liver in Adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 20 December 2019

Childhood Socioeconomic Status and Arterial Stiffness in Adulthood: The Cardiovascular Risk in Young Finns Study

artículo científico

Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthood

artículo científico publicado en 2018

Childhood and long-term dietary calcium intake and adult cardiovascular risk in a population with high calcium intake

artículo científico publicado en 2020

Childhood environmental and genetic predictors of adulthood obesity: the cardiovascular risk in young Finns study

artículo científico publicado en 2011

Childhood exposure to parental smoking and life-course overweight and central obesity

artículo científico publicado en 2020

Childhood nutrition in predicting metabolic syndrome in adults: the cardiovascular risk in Young Finns Study

artículo científico publicado en 2012

Childhood physical, environmental, and genetic predictors of adult hypertension: the cardiovascular risk in young Finns study

artículo científico publicado en 2012

Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

Childhood risk factors and carotid atherosclerotic plaque in adulthood: The Cardiovascular Risk in Young Finns Study

scientific article published on 30 November 2019

Childhood serum cholesterol ester fatty acids are associated with blood pressure 27 y later in the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2012

Cholesterol absorption and synthesis in pediatric kidney, liver, and heart transplant recipients

artículo científico publicado en 2006

Cholesterol-lowering properties and safety of chitosan

artículo científico publicado en 2002

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation

artículo científico publicado en 2014

Circulating cell-free DNA in health and disease — the relationship to health behaviours, ageing phenotypes and metabolomics

artículo científico publicado en 2022

Circulating cell-free DNA is associated with cardiometabolic risk factors: The Health 2000 Survey

article

Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ Study

artículo científico publicado en 2012

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

artículo científico publicado en 2018

Circulating metabolite predictors of glycemia in middle-aged men and women

artículo científico publicado en 2012

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

scientific article published on 04 October 2019

Circulating microRNAs as biomarkers in progressive multiple sclerosis

artículo científico publicado en 2016

Circulating oxidized low-density lipoprotein and common carotid artery intima-media thickness in a random sample of middle-aged men.

artículo científico publicado en 2004

Cognitive performance in young adulthood and midlife: Relations with age, sex, and education-The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Cohort Profile: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2008

Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk

artículo científico publicado en 2019

Combined assessment of heart rate recovery and T-wave alternans during routine exercise testing improves prediction of total and cardiovascular mortality: the Finnish Cardiovascular Study

artículo científico publicado en 2009

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation

scientific article published on 01 February 2019

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published 16 May 2018 in Neuron

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published September 2018 in Neuron

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills

scientific article published on 23 December 2013

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants in Mendelian kidney disease genes and their association with renal function

artículo científico publicado en 2013

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2009

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

artículo científico publicado en 2014

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts

artículo científico publicado en 2011

Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study

artículo científico publicado en 2008

Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study

artículo científico publicado en 2012

Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk

artículo científico publicado en 2012

Consortium genome-wide meta-analysis for childhood dental caries traits

Consortium-based genome-wide meta-analysis for childhood dental caries traits

scholarly article by Simon Haworth published in September 2018

Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study

artículo científico publicado en 2010

Conventional cardiovascular risk factors and metabolic syndrome in predicting carotid intima-media thickness progression in young adults: the cardiovascular risk in young Finns study.

artículo científico publicado en 2009

Coronary Artery Disease-Associated Locus on Chromosome 9p21 and Early Markers of Atherosclerosis

artículo científico publicado en 2008

Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: the Helsinki Sudden Death Study

scientific article published on 01 October 2002

Coronary artery wall atherosclerosis in relation to the estrogen receptor 1 gene polymorphism: an autopsy study

scientific article published on 17 January 2002

Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study

scientific article published on 15 November 2018

Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study

artículo científico publicado en 2015

Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy

artículo científico publicado en 2007

Correction: Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

artículo científico publicado en 2013

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

artículo científico publicado en 2020

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

artículo científico publicado en 2019

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

artículo científico publicado en 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Cross-sectional associations between physical activity and selected coronary heart disease risk factors in young adults. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2011

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

artículo científico publicado en 2021

DRD2 C32806T modifies the effect of child-rearing environment on adulthood novelty seeking

artículo científico publicado en 2009

Decreased endothelin-1 levels after acute consumption of red wine and de-alcoholized red wine

artículo científico publicado en 2010

Deficiency in Melanocortin 1 Receptor Signaling Predisposes to Vascular Endothelial Dysfunction and Increased Arterial Stiffness in Mice and Humans

artículo científico publicado en 2015

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

scientific article published on 04 August 2013

Delta-6-desaturase gene polymorphism is associated with lipoprotein oxidation in vitro

artículo científico publicado en 2013

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

artículo científico publicado en 2011

Detection of smell print differences between nonmalignant and malignant prostate cells with an electronic nose

artículo científico publicado en 2012

Determinants of arterial nitrate-mediated dilatation in children: role of oxidized low-density lipoprotein, endothelial function, and carotid intima-media thickness

artículo científico publicado en 2004

Determinants of bone strength and fracture incidence in adult Finns: Cardiovascular Risk in Young Finns Study (the GENDI pQCT study)

article published in 2010

Determinants of exercise peak arterial blood pressure, circulatory power, and exercise cardiac power in a population based sample of Finnish male and female aged 30 to 47 years: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2014

Determinants of left ventricular diastolic function-The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2019

Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Determinants of short-term variation in arterial flow-mediated dilatation in healthy young men.

artículo científico publicado en 2006

Diagnostic accuracies of plasma creatinine, cystatin C, and glomerular filtration rate calculated by the Cockcroft-Gault and Levey (MDRD) formulas

artículo científico publicado en 2003

Diagnostic performance of plasma high sensitive C-reactive protein in detecting three-vessel coronary artery disease: modification by apolipoprotein E genotype

scientific article published on 01 January 2008

Diet does not explain the high prevalence of dyslipidaemia in paediatric renal transplant recipients

artículo científico publicado en 2007

Dietary composition as a determinant of plasma asymmetric dimethylarginine in subjects with mild hypercholesterolemia

artículo científico publicado en 2004

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study

artículo científico publicado en 2017

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study

artículo científico publicado en 2017

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study

scientific article published on 01 April 2019

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Distinct child-to-adult body mass index trajectories are associated with different levels of adult cardiometabolic risk

artículo científico publicado en 2018

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

artículo científico publicado en 2013

Distinct variants at LIN28B influence growth in height from birth to adulthood

artículo científico publicado en 2010

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Do childhood infections affect labour market outcomes in adulthood and, if so, how?

artículo científico publicado en 2020

Does Compassion Predict Blood Pressure and Hypertension? The Modifying Role of Familial Risk for Hypertension

artículo científico publicado en 2020

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

artículo científico publicado en 2014

Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization

artículo científico publicado en 2018

Does high optimism protect against the inter-generational transmission of high BMI? The Cardiovascular Risk in Young Finns Study.

artículo científico publicado en 2017

Does higher education protect against obesity? Evidence using Mendelian randomization

artículo científico publicado en 2017

Does neuregulin-1 play a role in Type A behavior? The cardiovascular risk in young Finns study

artículo científico publicado en 2008

Dopamine 2 receptor C957T and catechol-o-methyltransferase Val158Met polymorphisms are associated with treatment response in electroconvulsive therapy

artículo científico publicado en 2008

Dopamine receptor D2 -141C Insertion/Deletion polymorphism in a Finnish population with schizophrenia

artículo científico publicado en 2003

Dopamine receptor D2 gene Taq1A (C32806T) polymorphism modifies the relationship between birth weight and educational attainment in adulthood: 21-year follow-up of the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2007

Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

East-west differences and migration in Finland: Association with cardiometabolic risk markers and IMT. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

Education leads to a more physically active lifestyle: Evidence based on Mendelian randomization

scientific article published on 16 March 2020

Effect of age, gender and cardiovascular risk factors on carotid distensibility during 6-year follow-up. The cardiovascular risk in Young Finns study

scholarly article by Juha Koskinen et al published October 2012 in Atherosclerosis

Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients

artículo científico publicado en 2013

Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Effect of common KCNE1 and SCN5A ion channel gene variants on T-wave alternans, a marker of cardiac repolarization, during clinical exercise stress test: the Finnish Cardiovascular Study

article

Effect of heart rate correction on pre- and post-exercise heart rate variability to predict risk of mortality-an experimental study on the FINCAVAS cohort

artículo científico publicado en 2014

Effect of high-dose statin treatment on plasma concentrations of endogenous nitric oxide synthase inhibitors

artículo científico publicado en 2003

Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to functional apolipoprotein e genotype

artículo científico publicado en 2002

Effect of long-term hormone replacement therapy on atherosclerosis progression in postmenopausal women relates to myeloperoxidase promoter polymorphism

artículo científico publicado en 2003

Effect of pravastatin on plasma sterols and oxysterols in men.

artículo científico publicado en 2005

Effect of the cessation of long-term hormone replacement therapy on plasma plasminogen activator inhibitor-1 and fibrinogen

artículo científico publicado en 2005

Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance

artículo científico publicado en 2008

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

artículo científico publicado en 2015

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men.

artículo científico publicado en 2008

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

artículo científico publicado en 2016

Effects of long-term estrogen replacement therapy versus combined hormone replacement therapy on nitric oxide-dependent vasomotor function

artículo científico publicado en 2003

Effects of polymorphisms in β1-adrenoceptor and α-subunit of G protein on heart rate and blood pressure during exercise test. The Finnish Cardiovascular Study

scholarly article by Tuomo Nieminen et al published February 2006 in Journal of Applied Physiology

Effects of weight loss on visceral and abdominal subcutaneous adipose tissue blood-flow and insulin-mediated glucose uptake in healthy obese subjects

artículo científico publicado en 2009

Elevated serum C-reactive protein levels and early arterial changes in healthy children

scientific article published on 01 August 2002

Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes

artículo científico publicado en 2004

Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study

artículo científico publicado en 2002

Enhanced predictive power of quantitative TWA during routine exercise testing in the Finnish Cardiovascular Study

artículo científico publicado en 2008

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics

scientific article published on 16 January 2020

Epidermal growth factor A61G polymorphism and cardiac autonomic control in adults

artículo científico publicado en 2005

Epidermal growth factor a61g polymorphism is associated with the age of onset of schizophrenia in male patients

artículo científico publicado en 2005

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

scientific article published on 07 February 2020

Epigenome-450K-wide methylation signatures of active cigarette smoking: the Young Finns Study

artículo científico publicado en 2020

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

article

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Estrogen Receptor 2 Polymorphism and Carotid Intima-Media Thickness

Estrogen receptor genotype modulates myocardial perfusion in young men.

artículo científico publicado en 2004

European lactase persistence genotype shows evidence of association with increase in body mass index

artículo científico publicado en 2009

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis

artículo científico publicado en 2021

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

artículo científico publicado en 2013

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Evidence of inbreeding depression on human height

artículo científico publicado en 2012

Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts

artículo científico publicado en 2021

Exercise electrocardiography detection of coronary artery disease by ST-segment depression/heart rate hysteresis in women: the Finnish Cardiovascular Study

artículo científico publicado en 2008

Exercise-test-related heart rate variability and mortality

article published in 2010

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

artículo científico publicado en 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

artículo científico publicado en 2017

Exploring causality between TV viewing and weight change in young and middle-aged adults. The Cardiovascular Risk in Young Finns study

artículo científico publicado en 2014

Exposure to heavy physical work from early to later adulthood and primary healthcare visits due to musculoskeletal diseases in midlife: a register linked study

scientific article published on 27 August 2019

Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

artículo científico publicado en 2008

Extended Serum Lipid Profile Predicting Long-Term Survival in Patients Treated for Abdominal Aortic Aneurysms

artículo científico publicado en 2017

Extensive phenotype data and machine learning in prediction of mortality in acute coronary syndrome - the MADDEC study

artículo científico publicado en 2019

FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity

artículo científico publicado en 2009

Factors associated with six-year weight change in young and middle-aged adults in the Young Finns Study

artículo científico publicado en 2015

Fast 5-hour determination of angiotensin-converting enzyme genotypes from blood by SDS–PAGE using PhastSystem ⬇️

artículo científico publicado el 8 de agosto de 1997

Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study.

artículo científico

Fatty acid and cholesterol composition of the uterine artery intima in relation to menopausal status, age, and serum cholesterol

artículo científico publicado en 2004

Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study.

artículo científico publicado en 2018

Fetal Growth and Preterm Birth Influence Cardiovascular Risk Factors and Arterial Health in Young Adults

article

Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2012

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

artículo científico publicado en 2015

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

artículo científico publicado en 2018

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

artículo científico publicado en 2013

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations

Gene expression profiles in Finnish twins with multiple sclerosis

artículo científico publicado en 2006

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

artículo científico publicado en 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study

article

Gene-environment interactions between education and body mass: Evidence from the UK and Finland

artículo científico publicado en 2017

Genes involved in systemic and arterial bed dependent atherosclerosis--Tampere Vascular study

artículo científico publicado en 2012

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease

scientific article published on 01 May 2019

Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns

artículo científico publicado en 2018

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

artículo científico publicado en 2017

Genetic Polymorphisms Associated With Constipation and Anticholinergic Symptoms in Patients Receiving Clozapine

artículo científico publicado en 2018

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic Variants in the DRD2 Gene Moderate the Relationship Between Stressful Life Events and Depressive Symptoms in Adults: Cardiovascular Risk in Young Finns Study

article

Genetic analysis for a shared biological basis between migraine and coronary artery disease

artículo científico publicado en 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental perturbations lead to regulatory decoherence

artículo científico publicado en 2019

Genetic association study of childhood aggression across raters, instruments, and age

artículo científico publicado en 2021

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

artículo científico publicado en 2014

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

artículo científico publicado en 2014

Genetic determinants of serum testosterone concentrations in men.

artículo científico publicado en 2011

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

artículo científico publicado en 2013

Genetic endowments, parental resources and adult health: Evidence from the Young Finns Study.

artículo científico publicado en 2017

Genetic evidence of assortative mating in humans

scholarly article

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

artículo científico publicado en 2022

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort

artículo científico publicado en 2013

Genetic polymorphism of sterol transporters in children with future gallstones

artículo científico publicado en 2018

Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

artículo científico publicado en 2019

Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--

artículo científico publicado en 2012

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic study of circulating cytokines offers insight into the determinants, cascades and effects of systemic inflammation

artículo científico publicado en 2020

Genetic variant of the SREBF-1 gene is significantly related to cholesterol synthesis in man.

artículo científico publicado en 2005

Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2011

Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study

artículo científico publicado en 2010

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variants of TSLP and asthma in an admixed urban population

artículo científico publicado en 2011

Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults

artículo científico publicado en 2014

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study

artículo científico publicado en 2022

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population

artículo científico publicado en 2017

Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events

scholarly article by Kari-Matti Mäkelä et al published February 2013 in Circulation: Cardiovascular Genetics

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

artículo científico publicado en 2017

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

artículo científico publicado en 2016

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

artículo científico publicado en 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

artículo científico publicado en 2016

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

artículo científico publicado en 2017

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

artículo científico publicado en 2022

Genome-wide association analysis identifies susceptibility loci for migraine without aura

artículo científico publicado en 2012

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

artículo científico publicado en 2015

Genome-wide association and functional follow-up reveals new loci for kidney function

artículo científico publicado en 2012

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity

artículo científico publicado en 2013

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

artículo científico publicado en 2019

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

artículo científico publicado en 2018

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of childhood and adolescent internalising symptoms

artículo científico publicado en 2020

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.

artículo científico publicado en 2017

Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent

artículo científico publicado en 2020

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

artículo científico publicado en 2021

Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.

artículo científico publicado en 2012

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

artículo científico publicado en 2014

Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.

artículo científico publicado en 2013

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

artículo científico publicado en 2012

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns

artículo científico publicado en 2019

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns:

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

artículo científico publicado en 2016

Genome-wide association study of kidney function decline in individuals of European descent

artículo científico publicado en 2014

Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

scientific article published on 04 July 2018

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

artículo científico publicado en 2014

Genome-wide association study of sleep duration in the Finnish population

artículo científico publicado en 2014

Genome-wide association study of white-coat effect in hypertensive patients

scientific article published on 02 May 2019

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality

artículo científico publicado en 2013

Genome-wide associations for birth weight and correlations with adult disease

artículo científico publicado en 2016

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

artículo científico publicado en 2013

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

artículo científico publicado en 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis identifies new susceptibility loci for migraine

artículo científico publicado en 2013

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

artículo científico publicado en 2014

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

artículo científico publicado en 2018

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

artículo científico publicado en 2016

Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study

artículo científico publicado en 2020

HDL enhances oxidation of LDL in vitro in both men and women

artículo científico publicado en 2005

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

artículo científico publicado en 2018

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

artículo científico publicado en 2014

Health endowment and later-life outcomes in the labour market: Evidence using genetic risk scores and reduced-form models

article

Heart rate variability derived from exercise ECG in the detection of coronary artery disease

scholarly article by Matti Virtanen et al published 18 September 2007 in Physiological Measurement

Heart rate variability is independently associated with C-reactive protein but not with Serum amyloid A. The Cardiovascular Risk in Young Finns Study

scholarly article by Atte Haarala et al published 17 February 2011 in European Journal of Clinical Investigation

Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women

artículo científico publicado en 2005

High birth weight is associated with obesity and increased carotid wall thickness in young adults: the cardiovascular risk in young Finns study

artículo científico publicado en 2014

High dose of red wine elicits enhanced inhibition of fibrinolysis

artículo científico publicado en 2009

High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis

artículo científico publicado en 2013

High perceived social support protects against the intergenerational transmission of obesity: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms

artículo científico publicado en 2014

High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels

artículo científico publicado en 2006

High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial

artículo científico publicado en 2005

High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis

artículo científico publicado en 2012

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

artículo científico publicado en 2009

Higher maternal body mass index is associated with an increased risk for later type 2 diabetes in offspring

artículo científico publicado en 2012

Higher step count is associated with greater bone mass and strength in women but not in men

Histaminergic gene polymorphisms associated with sedation in clozapine-treated patients

artículo científico publicado en 2017

Homocysteine and carotid atherosclerosis in chronic renal failure--the confounding effect of renal function

artículo científico publicado en 2004

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease

article

INSIG2 polymorphism and weight gain, dyslipidemia and serum adiponectin in Finnish patients with schizophrenia treated with clozapine

artículo científico publicado en 2016

Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2012

Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion

artículo científico publicado en 2017

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure

artículo científico publicado en 2020

IgA levels are predictors of mortality in Finnish nonagenarians

artículo científico publicado en 2005

Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study ⬇️

artículo científico publicado en 2018

Impact of blood pressure on retinal microvasculature architecture across the lifespan: the Young Finns Study

artículo científico publicado en 2015

Impact of fetal growth and preterm birth on the retinal microvasculature in mid-adulthood

artículo científico publicado en 2015

Impact of long-term hormone replacement therapy on in vivo and in vitro markers of lipid oxidation

artículo científico publicado en 2004

Impaired exercise capacity predicts sudden cardiac death in a low-risk population: Enhanced specificity with heightened T-wave alternans

Importance of regional specificity of T-wave alternans in assessing risk for cardiovascular mortality and sudden cardiac death during routine exercise testing

scientific article published on 05 November 2010

Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria

artículo científico publicado en 2015

Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration

article published in 2019

Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery

artículo científico publicado en 2017

Increased calcium intake reduces plasma cholesterol and improves vasorelaxation in experimental renal failure

artículo científico publicado en 2003

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

artículo científico publicado en 2012

Increased serum matrix metalloproteinase 9 levels in systemic lupus erythematosus patients with neuropsychiatric manifestations and brain magnetic resonance imaging abnormalities

artículo científico publicado en 2004

Increased tooth brushing frequency is associated with reduced gingival pocket bacterial diversity in patients with intracranial aneurysms

scientific article published in 2019

Indoleamine 2,3-dioxygenase activation and depressive symptoms: results from the Young Finns Study

artículo científico publicado en 2012

Infection-Related Hospitalization in Childhood and Adult Metabolic Outcomes

artículo científico publicado en 2015

Inflammation, adiposity, and mortality in the oldest old.

artículo científico publicado en 2012

Influence of Child and Adult Elevated Blood Pressure on Adult Arterial Stiffness: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2017

Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke

artículo científico publicado en 2019

Influence of apolipoprotein E polymorphism on serum lipid and lipoprotein changes: a 21-year follow-up study from childhood to adulthood. The Cardiovascular Risk in Young Finns Study

scholarly article by Paula Grönroos et al published 1 January 2007 in Clinical Chemistry and Laboratory Medicine

Influence of early-lifebody mass index and systolic blood pressure on left ventricle in adulthood - The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2020

Insulin and BMI as predictors of adult type 2 diabetes mellitus

artículo científico publicado en 2014

Insulin resistance, LDL particle size, and LDL susceptibility to oxidation in pediatric kidney and liver recipients

artículo científico publicado en 2005

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

artículo científico publicado en 2012

Integrative approaches for large-scale transcriptome-wide association studies

artículo científico publicado en 2016

Interaction between NOTCH4 and catechol-O-methyltransferase genotypes in schizophrenia patients with poor response to typical neuroleptics

artículo científico publicado en 2004

Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neuroleptics

artículo científico publicado en 2003

Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns

artículo científico publicado en 2004

Interaction between two HTR2A polymorphisms and gender is associated with treatment response in MDD.

artículo científico publicado en 2011

Interaction of tumor necrosis alpha - G308A and epidermal growth factor gene polymorphisms in early-onset schizophrenia

artículo científico publicado en 2004

Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children

artículo científico publicado en 2014

Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis

artículo científico publicado en 2008

Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

article

Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals.

artículo científico publicado en 2003

Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ study

artículo científico publicado en 2007

Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study

article

Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study

artículo científico publicado en 2007

Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men.

artículo científico publicado en 2003

Interleukin-6 and microRNA profiles induced by oral bacteria in human atheroma derived and healthy smooth muscle cells

artículo científico publicado en 2015

Interleukin-6 gene polymorphism, chronic stress and atherosclerosis

article

Interleukin-6 modulates plasma cholesterol and C-reactive protein concentrations in nonagenarians

artículo científico publicado en 2005

Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey.

artículo científico publicado en 2009

International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents

artículo científico publicado en 2016

Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure

artículo científico publicado en 2012

Intraneuronal Abeta immunoreactivity is not a predictor of brain amyloidosis-beta or neurofibrillary degeneration

artículo científico publicado en 2007

Is 5-HTTLPR linked to the response of selective serotonin reuptake inhibitors in MDD?

artículo científico publicado en 2010

Is It Good To Be Good? Dispositional Compassion and Health Behaviors

scientific article published on 01 June 2019

Is dispositional optimism or dispositional pessimism predictive of ideal cardiovascular health? The Young Finns Study

artículo científico publicado en 2015

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds

artículo científico publicado en 2015

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

artículo científico publicado en 2012

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

artículo científico publicado en 2017

Left ventricular ejection fraction adds value over the GRACE score in prediction of 6-month mortality after ACS: the MADDEC study

scientific article published on 27 June 2019

Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene and changes in serum lipids during a family-based counselling intervention among school-aged children with a family history of CVD.

artículo científico publicado en 2008

Leukocyte telomere length is inversely associated with arterial wave reflection in 566 normotensive and never-treated hypertensive subjects

artículo científico publicado en 2020

Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2010

Life-course risk factor levels and coronary artery calcification. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

Life-time risk factors and progression of carotid atherosclerosis in young adults: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2010

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2008

Lifetime fruit and vegetable consumption and arterial pulse wave velocity in adulthood: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2010

Lifetime risk factors and arterial pulse wave velocity in adulthood: the cardiovascular risk in young Finns study

artículo científico publicado en 2010

Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23

artículo científico publicado en 1998

Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study

scientific article published on 21 November 2019

Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease

artículo científico publicado en 2013

Lipoprotein docosapentaenoic acid is associated with serum matrix metalloproteinase-9 concentration

artículo científico publicado en 2005

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

artículo científico publicado en 2019

Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity

artículo científico publicado en 2010

Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes

artículo científico publicado en 2006

Long-term leisure-time physical activity and serum metabolome

artículo científico publicado en 2012

Long-term outcome of intraventricular conduction delays in the general population

scientific article published on 17 August 2020

Long-term prognostic significance of the ST level and ST slope in the 12‑lead ECG in the general population

artículo científico publicado en 2019

Longitudinal Associations of Explosive and Adventurous Temperament Profiles With Character Development: The Modifying Effects of Social Support and Attachment

artículo científico publicado en 2018

Longitudinal association of a body mass index (BMI) genetic risk score with growth and BMI changes across the life course: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2020

Longitudinal associations of temperament and character with paranoid ideation: A population-based study

artículo científico publicado en 2017

Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study

scientific journal article

Longitudinal study of circulating oxidized LDL and HDL and fatty liver: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease

artículo científico publicado en 2007

Low serum adiponectin levels in childhood and adolescence predict increased intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs

artículo científico publicado en 2009

Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding

artículo científico publicado en 2012

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

artículo científico publicado en 2019

Maternal and infant characteristics connected to shared pleasure in dyadic interaction

scientific article published on 13 May 2019

Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques

artículo científico publicado en 2004

Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages

artículo científico publicado en 2017

Melatonin pathway genes are associated with progressive subtypes and disability status in multiple sclerosis among Finnish patients

artículo científico publicado en 2012

Mendelian Randomization Suggests No Causal Association Between C-reactive Protein and Carotid Intima-media Thickness in the Young Finns Study

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

artículo científico publicado en 2020

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

artículo científico publicado en 2015

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

artículo científico publicado en 2015

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

artículo científico publicado en 2011

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

artículo científico publicado en 2020

Metabolic Effects Of Risk Alleles In PNPLA3, TM6SF2, GCKR, And LYPLAL1 Inform About Heterogeneity Of Non-Alcoholic Fatty Liver Disease

artículo científico publicado en 2017

Metabolic profiles of socio-economic position: a multi-cohort analysis

artículo científico publicado en 2020

Metabolic profiling of alcohol consumption in 9778 young adults

artículo científico publicado en 2016

Metabolic profiling of alcohol consumption in 9778 young adults

artículo científico publicado en 2016

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis

artículo científico publicado en 2020

Metabolic profiling of fatty liver in young and middle-aged adults: Cross-sectional and prospective analyses of the Young Finns Study

artículo científico publicado en 2016

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence

artículo científico publicado en 2016

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change

artículo científico publicado en 2014

Metabolic signatures of birth weight in 18288 adolescents and adults

artículo científico publicado en 2016

Metabolic signatures of birthweight in 18 288 adolescents and adults.

artículo científico publicado en 2016

Metabolic signatures of insulin resistance in 7,098 young adults

artículo científico publicado en 2012

Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey

artículo científico publicado en 2008

Metabolic syndrome in childhood and increased arterial stiffness in adulthood: the Cardiovascular Risk In Young Finns Study

artículo científico publicado en 2011

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

artículo científico publicado en 2015

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

artículo científico publicado en 2016

Methylation status of VTRNA2-1 / nc886 is stable across populations, monozygotic twin pairs and in majority of tissues

artículo científico publicado en 2022

Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs

artículo científico publicado en 2021

MicroRNAs in the atherosclerotic plaque

artículo científico

Microcrystalline chitosan is ineffective to decrease plasma lipids in both apolipoprotein E epsilon 4 carriers and non-carriers: a long-term placebo-controlled trial in hypercholesterolaemic volunteers

artículo científico publicado en 2005

Microduplications of 16p11.2 are associated with schizophrenia

artículo científico publicado en 2009

Migraine without aura: genome-wide association analysis identifies several novel susceptibility.

artículo científico publicado en 2013

Mitochondrial diabetes is associated with insulin resistance in subcutaneous adipose tissue but not with increased liver fat content

artículo científico publicado en 2011

Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci

artículo científico publicado en 2021

Model selection for metabolomics: predicting diagnosis of coronary artery disease using automated machine learning

scientific article published on 01 March 2020

Moderating effect of indoleamine 2,3-dioxygenase (IDO) activation in the association between depressive symptoms and carotid atherosclerosis: evidence from the Young Finns study

artículo científico publicado en 2011

Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism

article

Modular genome-wide gene expression architecture shared by early traits of osteoporosis and atherosclerosis in the Young Finns Study

artículo científico publicado en 2021

Motherhood and oxytocin receptor genetic variation are associated with selective changes in electrocortical responses to infant facial expressions.

artículo científico publicado en 2014

Moving on: How depressive symptoms, social support, and health behaviors predict residential mobility

artículo científico publicado en 2015

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

artículo científico publicado en 2021

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

artículo científico publicado en 2021

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

artículo científico publicado en 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

artículo científico publicado en 2019

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

artículo científico publicado en 2017

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

artículo científico publicado en 2016

Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy

scientific article published on 31 October 2019

Myeloperoxidase Gene Variation and Coronary Flow Reserve in Young Healthy Men

article

Myeloperoxidase gene variation and coronary flow reserve in young healthy men.

artículo científico publicado en 2004

Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.

artículo científico publicado en 2003

Myocardial infarction induces early increased remote ADAM8 expression of rat hearts after cardiac arrest

scientific article published on 06 July 2011

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR, and LYPLAL1 show divergent metabolic effects

artículo científico publicado en 2018

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

artículo científico

NOTCH4 gene promoter polymorphism is associated with the age of onset in schizophrenia

artículo científico publicado en 2003

Neighborhood effects in depressive symptoms, social support, and mistrust: Longitudinal analysis with repeated measurements

artículo científico publicado en 2015

Neighbourhood effects in health behaviours: a test of social causation with repeat-measurement longitudinal data

artículo científico publicado en 2015

Neuregulin genotype and medication response in Finnish patients with schizophrenia

scientific article published on 01 November 2004

Neuregulin-1 genotype moderates the association between job strain and early atherosclerosis in young men

artículo científico publicado en 2007

Neuropeptide Y signal peptide Pro7 substitution protects against coronary artery atherosclerosis: the Helsinki Sudden Death Study

artículo científico publicado en 2007

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

scientific article published on 29 July 2019

New biomarker evidence of oxidative DNA damage in patients with non‐insulin‐dependent diabetes mellitus ⬇️

artículo científico publicado el 3 de noviembre de 1997

New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults

scientific article published on 03 July 2019

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

artículo científico publicado en 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

artículo científico publicado en 2012

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.

artículo científico publicado en 2003

Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components

artículo científico publicado en 2010

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

artículo científico publicado en 2013

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

No association of nineteen COX-2 gene variants to preclinical markers of atherosclerosis The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2012

No support for a role for BDNF gene polymorphisms rs11030101 and rs61888800 in major depressive disorder or antidepressant response in patients of Finnish origin

artículo científico publicado en 2013

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis

artículo científico publicado en 2012

Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling

artículo científico publicado en 2011

Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk

article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

artículo científico publicado en 2020

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals

scientific article published on 14 February 2017

Ophthalmic epidemiology in Europe: the "European Eye Epidemiology" (E3) consortium

artículo científico publicado en 2015

Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy

scientific article published on 01 June 2019

Oxidized LDL autoantibodies are related to apolipoprotein E phenotype, independently of postprandial change in plasma triglycerides and LDL size, among patients with angiographically verified coronary artery disease and healthy controls

artículo científico publicado en 2003

Oxytocin receptor gene (OXTR) variant rs1042778 moderates the influence of family environment on changes in perceived social support over time

article

P2RX7 polymorphisms Gln460Arg and His155Tyr are not associated with major depressive disorder or remission after SSRI or ECT.

artículo científico publicado en 2011

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation

artículo científico publicado en 2018

Paraoxonase-1 and oxidized lipoprotein lipids. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Parental Smoking in Childhood and Brachial Artery Flow-Mediated Dilatation in Young Adults

article

Pattern of crescendo TWA may disclose the underlying cardiac pathology

artículo científico publicado en 2010

Personality traits and perceptions of organisational justice.

artículo científico publicado en 2018

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease

artículo científico publicado en 2008

Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery

scientific article published on 01 February 2019

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

artículo científico publicado en 2017

Plasma asymmetric dimethylarginine and retinal vessel diameters in middle-aged men.

artículo científico publicado en 2007

Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults

artículo científico publicado en 2003

Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy

artículo científico publicado en 2003

Plasma-soluble CD40 is related to cholesterol metabolism in patients with moderate hypercholesterolemia

artículo científico publicado en 2006

Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study

scholarly article by Juho R.H. Raiko et al published September 2012 in Atherosclerosis

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Polymorphism in alpha 2A adrenergic receptor gene is associated with sialorrhea in schizophrenia patients on clozapine treatment

artículo científico publicado en 2014

Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey

Polymorphism in the IL10 promoter region and early markers of atherosclerosis: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2009

Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2008

Polymorphism of the angiotensin-converting enzyme (ACE) and angiotesinogen (AGT) genes and their associations with blood pressure and carotid artery intima media thickness among healthy Finnish young adults—the Cardiovascular Risk in Young Finns St

article

Polymorphism of the cytokine genes and IgA nephropathy

artículo científico publicado en 2002

Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study

article

Positive Psychosocial Factors in Childhood Predicting Lower Risk for Adult Type 2 Diabetes: The Cardiovascular Risk in Young Finns Study, 1980-2012.

artículo científico publicado en 2017

Post-Exercise Assessment of Cardiac Repolarization Alternans in Patients With Coronary Artery Disease Using the Modified Moving Average Method

scientific article published on 01 March 2009

Postexercise recovery of the spatial QRS/T angle as a predictor of sudden cardiac death

article by Tuomas Kenttä et al published July 2012 in Heart Rhythm

Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals

scientific article published on 12 September 2019

Predicting sudden cardiac death using common genetic risk variants for coronary artery disease

artículo científico publicado en 2015

Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2017

Prediction of Adulthood Obesity Using Genetic and Childhood Clinical Risk Factors in the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2017

Prediction of coronary artery disease by transesophageal echocardiographic detection of thoracic aortic plaque in patients with chronic kidney disease

scientific article published on 24 April 2006

Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma

artículo científico publicado en 2013

Prevalence and determinants of fatty liver in normal-weight and overweight young adults. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2014

Prevalence and prognostic value of poor R-wave progression in standard resting electrocardiogram in a general adult population. The Health 2000 Survey

scientific article published on 01 March 2010

Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis - Tampere Vascular Study

artículo científico publicado en 2018

Prognostic capacity of a clinically indicated exercise test for cardiovascular mortality is enhanced by combined analysis of exercise capacity, heart rate recovery and T-wave alternans

artículo científico publicado en 2014

Prognostic implications of intraventricular conduction delays in a general population: the Health 2000 Survey

artículo científico publicado en 2015

Prognostic implications of quantitative ST-segment characteristics and T-wave amplitude for cardiovascular mortality in a general population from the Health 2000 Survey

artículo científico publicado en 2010

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

artículo científico publicado en 2016

Promoter polymorphism of IL-10 and severity of multiple sclerosis ⬇️

artículo científico publicado el 1 de diciembre de 2003

Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.

artículo científico publicado en 2011

Prospective relationship of change in ideal cardiovascular health status and arterial stiffness: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2014

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Psychosocial environment in childhood and body mass index growth over 32years

artículo científico publicado en 2016

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults

artículo científico publicado en 2018

Pulse wave velocity is related to exercise blood pressure response in young adults. The Cardiovascular Risk in Young Finns Study

scientific article published on 15 April 2020

QRS-T morphology measured from exercise electrocardiogram as a predictor of cardiac mortality

scientific article published on 24 December 2010

RGS4 polymorphism and response to electroconvulsive therapy in major depressive disorder

artículo científico publicado en 2008

RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease

scientific article published on 10 December 2019

Rapid and accurate detection of urinary pathogens by mobile IMS-based electronic nose: a proof-of-principle study

artículo científico publicado en 2014

Rapid apolipoprotein E genotyping from mailed buccal swabs ⬇️

artículo científico publicado el 31 de enero de 1998

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Reciprocal relationships between psychosocial work characteristics and sleep problems: A two-wave study

Reference Values for Echocardiography in Middle-Aged Population: The Cardiovascular Risk in Young Finns Study

Regional Differences in Apolipoprotein E Polymorphism in Finland

artículo científico publicado en 1991

Regulatory variant of the TPH2 gene and early life stress are associated with heightened attention to social signals of fear in infants

artículo científico publicado en 2013

Relation of Apolipoprotein E Polymorphism to Markers of Early Atherosclerotic Changes in Young Adults

scientific article published on 01 January 2008

Relation of intraventricular conduction delay to risk of new-onset heart failure and structural heart disease in the general population

scientific article published on 25 September 2020

Relation of positive T wave in lead aVR to risk of cardiovascular mortality

artículo científico publicado en 2011

Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults

artículo científico publicado en 2006

Relationship between leptin and C-reactive protein in young Finnish adults

artículo científico publicado en 2007

Reply

Response to Letters Regarding Article, “Bacterial Signatures in Thrombus Aspirates of Patients With Myocardial Infarction”

Risk factors for aortic atherosclerosis determined by transesophageal echocardiography in patients with CRF.

artículo científico publicado en 2003

Risk of obesity and metabolic syndrome associated with FTO gene variants discloses clinically relevant gender difference among Turks

artículo científico publicado en 2016

Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

SERT and NET polymorphisms, temperament and antidepressant response

artículo científico publicado en 2015

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

artículo científico publicado en 2016

Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study

artículo científico publicado en 2013

Sequentially combined estradiol valerate plus levonorgestrel therapy decreases 18:1 trans-fatty acid content of plasma lipids in healthy postmenopausal women

artículo científico publicado en 2005

Seropositivity for Helicobacter pylori antibodies is associated with lower occurrence of venous bypass graft occlusion

artículo científico publicado en 2004

Serotonin Receptor 2A Gene and the Influence of Childhood Maternal Nurturance on Adulthood Depressive Symptoms

article

Serotonin and early cognitive development: variation in the tryptophan hydroxylase 2 gene is associated with visual attention in 7-month-old infants

artículo científico publicado en 2011

Serotonin receptor 1B genotype and hostility, anger and aggressive behavior through the lifespan: the Young Finns study

artículo científico publicado en 2012

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression

artículo científico publicado en 2015

Serum TRACP 5b is a useful marker for monitoring alendronate treatment: comparison with other markers of bone turnover

artículo científico publicado en 2005

Serum apolipoprotein A-I concentration differs in coronary and peripheral artery disease

scientific article published on 03 June 2020

Serum fatty acid profile in celiac disease patients before and after a gluten-free diet.

artículo científico publicado en 2009

Serum fatty acid profile in subjects with irritable bowel syndrome

artículo científico publicado en 2010

Serum lipids in children 3 to 5 years after kidney, liver, and heart transplantation

artículo científico publicado en 2004

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates

artículo científico publicado en 2015

Sex-specific associations of TCF7L2 variants with fasting glucose, type 2 diabetes and coronary heart disease among Turkish adults

artículo científico publicado en 2020

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Similarity of salivary microbiome in parents and adult children

artículo científico publicado en 2020

Simplified definitions of elevated pediatric blood pressure and high adult arterial stiffness

artículo científico publicado en 2013

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study

artículo científico publicado en 2003

Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease

artículo científico publicado en 2012

Socioeconomic Status, Cardiovascular Risk Factors, and Subclinical Atherosclerosis in Young Adults

scholarly article by Paula Kestilä et al published March 2012 in Arteriosclerosis, Thrombosis, and Vascular Biology

Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis

article published in 2019

Somatic complaints in early adulthood predict the developmental course of compassion into middle age

artículo científico publicado en 2020

Statin Pharmacogenomics: Lipid Response and Cardiovascular Outcomes

article

Stature and long-term labor market outcomes: Evidence using Mendelian randomization.

artículo científico publicado en 2016

Strong association of de novo copy number mutations with autism

artículo científico publicado en 2007

Studies of LDL particle size and susceptibility to oxidation and association with glucose metabolism in children after heart transplantation

artículo científico publicado en 2004

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

artículo científico publicado en 2018

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

artículo científico publicado en 2019

Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis

artículo científico publicado en 2017

Suppression of immune system genes by methylprednisolone in exacerbations of multiple sclerosis. Preliminary results

artículo científico publicado en 2004

Survival related to plasma C-reactive-protein in nonagenarians is modified by apolipoprotein E genotype

artículo científico publicado en 2007

Sympathetic activity-associated periodic repolarization dynamics predict mortality following myocardial infarction

artículo científico publicado en 2014

Sympathetic activity–associated periodic repolarization dynamicspredict mortality following myocardial infarction.

artículo científico publicado en 2014

Synaptic, transcriptional and chromatin genes disrupted in autism

artículo científico publicado en 2014

Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols: the cardiovascular risk in Young Finns Study

artículo científico publicado en 2008

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia

artículo científico publicado en 2021

Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population

article by Matthias M. Mauschitz et al published October 2018 in Ophthalmology

Systemic hemodynamics in relation to glucose tolerance: the Health 2000 Survey

artículo científico publicado en 2010

Systemic hemodynamics in young adults with the metabolic syndrome: The Cardiovascular Risk in Young Finns Study

article published in 2010

Systemic vascular resistance predicts the development of hypertension: the cardiovascular risk in young Finns study

artículo científico publicado en 2020

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

artículo científico publicado en 2015

TPH1 218A/C polymorphism is associated with major depressive disorder and its treatment response

artículo científico publicado en 2009

TPH1 A218C polymorphism and temperament in major depression

artículo científico publicado en 2013

TPH2 polymorphisms may modify clinical picture in treatment-resistant depression

artículo científico publicado en 2009

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study

artículo científico publicado en 2016

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

Television viewing and fatty liver in early midlife. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2015

Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression

artículo científico publicado en 2010

Temperamental Activity and Epidermal Growth Factor A61G Polymorphism in Finnish Adults

scientific article published on 01 January 2007

The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks

artículo científico publicado en 2010

The Association Between Social Support, Body Mass Index and Increased Risk of Prediabetes: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

artículo científico publicado en 2015

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2016

The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans

article published in 2018

The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality

article

The Effect of Weight on Labor Market Outcomes: an Application of Genetic Instrumental Variables ⬇️

artículo científico publicado en 2016

The Finnish Cardiovascular Study (FINCAVAS): characterising patients with high risk of cardiovascular morbidity and mortality

artículo científico publicado en 2006

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Polygenic and Monogenic Basis of Blood Traits and Diseases

artículo científico publicado en 2020

The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients

artículo científico publicado en 2019

The Young Finns Study

artículo científico publicado en 2020

The apolipoprotein E polymorphism is not associated with response to electroconvulsive therapy in major depressive disorder

artículo científico publicado en 2005

The association between charlson comorbidity index and mortality in acute coronary syndrome - the MADDEC study

scientific article published on 28 November 2019

The association of myeloperoxidase promoter polymorphism with carotid atherosclerosis is abolished in patients with type 2 diabetes

artículo científico publicado en 2008

The association of the apolipoprotein E gene promoter polymorphisms and haplotypes with serum lipid and lipoprotein concentrations

artículo científico publicado en 2004

The associations of oxidized high-density lipoprotein lipids with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2013

The associations of oxidized lipoprotein lipids with lipoprotein subclass particle concentrations and their lipid compositions. The Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2020

The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis

artículo científico publicado en 2017

The challenges of GxE research: A rejoinder

artículo científico publicado en 2017

The co-occurrence between depressive symptoms and paranoid ideation: A population-based longitudinal study.

artículo científico publicado en 2017

The combined effects of apolipoprotein E polymorphism and low-density lipoprotein cholesterol on cognitive performance in young adults

artículo científico publicado en 2003

The contribution of neighborhood socioeconomic disadvantage on depressive symptoms over the adult lifetime: a 32-year prospective cohort study

artículo científico publicado en 2020

The effect of apolipoprotein E polymorphism on serum metabolome - a population-based 10-year follow-up study

artículo científico publicado en 2019

The effect of hormone replacement therapy on atherosclerotic severity in relation to ESR1 genotype in postmenopausal women

artículo científico publicado en 2003

The effect of long-term microcrystalline chitosan therapy on plasma lipids and glucose concentrations in subjects with increased plasma total cholesterol: a randomised placebo-controlled double-blind crossover trial in healthy men and women

artículo científico publicado en 2003

The effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men

The effect of weight on labor market outcomes: An application of genetic instrumental variables

The effects of adult-type hypolactasia on body height growth and dietary calcium intake from childhood into young adulthood: a 21-year follow-up study--the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2006

The effects of apoA-I/C-III/A-IV, apoE and apoB polymorphisms on carotid artery intima-media thickness

scientific article published on March 2006

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The influence of hepatic lipase C-480T polymorphism on coronary flow reserve in young men is independent of the plasma cholesterol level

artículo científico publicado en 2005

The influence of urban/rural residency on depressive symptoms is moderated by the serotonin receptor 2A gene

artículo científico publicado en 2007

The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness

artículo científico publicado en 2010

The molecular genetic architecture of self-employment

artículo científico publicado en 2013

The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study

article

The prevalence and prognostic significance of interatrial block in the general population

artículo científico publicado en 2020

The prevalence of peripheral arterial disease and medial arterial calcification in patients with chronic renal failure: requirements for diagnostics

artículo científico publicado en 2002

The prognostic significance of T-wave inversion according to ECG lead group during long-term follow-up in the general population

scientific article published on 25 September 2020

The relationship of dispositional compassion for others with depressive symptoms over a 15-year prospective follow-up

scientific article published on 06 March 2019

The relationship of sterol regulatory element-binding protein cleavage-activation protein and apolipoprotein E gene polymorphisms with metabolic changes during weight reduction

artículo científico publicado en 2007

The role of oxytocin receptor gene (OXTR) and mother's emotional warmth in predicting adulthood sociability

article

The role of oxytocinergic genes in the intergenerational transmission of parent-child relationship qualities

scientific article published on 20 July 2019

The serotonin receptor 2A gene moderates the influence of parental socioeconomic status on adulthood harm avoidance

artículo científico publicado en 2007

The serum copper/zinc ratio in childhood and educational attainment: a population-based study

artículo científico publicado en 2016

Three genetic-environmental networks for human personality

artículo científico publicado en 2019

Tissue inhibitor of matrix metalloproteinases 4 (TIMP4) in a population of young adults: Relations to cardiovascular risk markers and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study

Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage Activation

artículo científico publicado en 2012

Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study

artículo científico publicado en 2007

Tracking of serum lipid levels, blood pressure, and body mass index from childhood to adulthood: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2011

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

artículo científico publicado en 2020

Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adults

artículo científico publicado en 2006

Tryptophan hydroxylase 1 gene haplotypes modify the effect of a hostile childhood environment on adulthood harm avoidance

artículo científico publicado en 2006

Tumor necrosis factor-alpha --G308A polymorphism in schizophrenia in a Finnish population

artículo científico publicado en 2005

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

artículo científico publicado en 2016

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

artículo científico publicado en 2016

Uncovering the complex genetics of human character

article

Uncovering the complex genetics of human personality: response from authors on the PGMRA Model

artículo científico publicado en 2019

Uncovering the complex genetics of human temperament

article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

artículo científico publicado en 2014

Upstream transcription factor 1 (USF1) polymorphisms associate with Alzheimer's disease-related neuropathological lesions: Tampere Autopsy Study

artículo científico publicado en 2012

Urine headspace analysis with field asymmetric ion mobility spectrometry for detection of chronic kidney disease

artículo científico publicado en 2020

Use of combined oral contraceptives alters metabolic determinants and genetic regulation of C-reactive protein. The Cardiovascular Risk in Young Finns Study

scientific article published on 01 January 2009

Val/Met polymorphism of the COMT gene moderates the association between job strain and early atherosclerosis in young men.

artículo científico publicado en 2008

Value of leads V4R and CM5 in the detection of coronary artery disease during exercise electrocardiographic test

scholarly article by Merja Puurtinen et al published 24 May 2010 in Clinical Physiology and Functional Imaging

Valvular calcification and its relationship to atherosclerosis in chronic kidney disease

scientific article published on 01 July 2009

Variants associated with expression have sex-differential effects on lung function

artículo científico publicado en 2020

Variation of the transcription factor 7-like 2 (TCF7L2) gene predicts impaired fasting glucose in healthy young adults: the Cardiovascular Risk in Young Finns Study

artículo científico publicado en 2007

Vascular cell adhesion molecule 1, soluble Fas and hepatocyte growth factor as predictors of mortality in nonagenarians: the Vitality 90+ study

artículo científico publicado en 2013

Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depression

artículo científico publicado en 2010

Vitamin D and cognitive function: A Mendelian randomisation study

artículo científico publicado en 2017

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

artículo científico publicado en 2012

WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels

artículo científico publicado en 2008

Weight reduction with very-low-caloric diet and endothelial function in overweight adults: role of plasma glucose

artículo científico publicado en 2003

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.

artículo científico publicado en 2019

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

scholarly article

Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood

artículo científico publicado en 2019

Youth overweight and metabolic disturbances in predicting carotid intima-media thickness, type 2 diabetes, and metabolic syndrome in adulthood: the Cardiovascular Risk in Young Finns study

artículo científico publicado en 2014

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

artículo científico publicado en 2016

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

article published in 2011

Lista de obras de Terho Lehtimäki

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.

52 Genetic Loci Influencing Myocardial Mass

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

A Longitudinal Multilevel Study of the "Social" Genotype and Diversity of the Phenotype

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

A catalog of genetic loci associated with kidney function from analyses of a million individuals

A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

A diagnosis of the metabolic syndrome in youth that resolves by adult life is associated with a normalization of high carotid intima-media thickness and type 2 diabetes mellitus risk: the Bogalusa heart and cardiovascular risk in young Finns studies

A disintegrin and metalloprotease -8 and -15 and susceptibility for ascending aortic dissection.

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

A genome-wide association meta-analysis identifies new childhood obesity loci

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study

A meta-analysis of genome-wide association studies identifies multiple longevity genes

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

A metabolic view on menopause and ageing

A moderate dose of red wine, but not de-alcoholized red wine increases coronary flow reserve

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

A randomized trial of early detection of clinically significant prostate cancer (ProScreen): study design and rationale

A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

ACE polymorphism and response to electroconvulsive therapy in major depression

ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries--Tampere vascular study

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients

Activated immune-inflammatory pathways are associated with long-standing depressive symptoms: Evidence from gene-set enrichment analyses in the Young Finns Study

Activation of indoleamine 2,3-dioxygenase-induced tryptophan degradation in advanced atherosclerotic plaques: Tampere vascular study

Adhesion Molecules in Multiple Sclerosis

Adhesion molecules in multiple sclerosis: relation to subtypes of disease and methylprednisolone therapy

Adolescence Risk Factors Are Predictive of Coronary Artery Calcification at Middle Age

Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

Adverse childhood environment and self-reported sleep in adulthood: The Young Finns Study

Age and gender biases in secondary prevention of coronary heart disease in a Finnish university hospital setting

Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

Age-dependent association of gut bacteria with coronary atherosclerosis: Tampere Sudden Death Study

Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction--Helsinki Sudden Death Study

Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

Analysis of apoptosis-related genes in patients with clinically isolated syndrome and their association with conversion to multiple sclerosis

Analysis of free, mono- and diacetylated polyamines from human urine by LC-MS/MS.

Analysis of shared heritability in common disorders of the brain

Antibody titer against malondialdehyde-modified LDL compares with HDL cholesterol concentration in identifying angiographically verified coronary artery disease. Comparison of tests by ROC analysis

Aortic sinus diameter in middle age is associated with body size in young adulthood

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study

Apolipoprotein A-I/C-III/A-IV SstI and Apolipoprotein B XbaI Polymorphisms Do not Affect Early Functional and Structural Changes in Atherosclerosis

Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study

Apolipoprotein B is related to arterial pulse wave velocity in young adults: The Cardiovascular Risk in Young Finns Study

Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study

Apolipoprotein E gene polymorphism, hypercholesterolemia and glomerular filtration rate in type 2 diabetic subjects: a 9-year follow-up study.

Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenarians

Apolipoprotein E polymorphism is associated with age of onset in schizophrenia

Apoptosis-related molecules in blood in multiple sclerosis

Arterial pulse wave velocity in relation to carotid intima-media thickness, brachial flow-mediated dilation and carotid artery distensibility: The Cardiovascular Risk in Young Finns Study and the Health 2000 Survey

Arterial tension time reflects subclinical atherosclerosis, arterial stiffness and stroke volume

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

Association analysis of allelic variants of USF1 in coronary atherosclerosis

Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach

Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

Association of EGF polymorphism with schizophrenia in Finnish men.

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Association of Known Loci With Lipid Levels Among Children and Prediction of Dyslipidemia in Adults