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Lista de obras de Tõnu Esko

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

artículo científico publicado en 2017

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A common 16p11.2 inversion underlies the joint susceptibility to asthma and obesity

scientific article published on 20 February 2014

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis

artículo científico publicado en 2015

A genome-wide analysis of populations from European Russia reveals a new pole of genetic diversity in northern Europe

artículo científico publicado en 2013

A genome-wide association study of early menopause and the combined impact of identified variants

artículo científico publicado en 2013

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

artículo científico publicado en 2021

A meta-analysis of gene expression signatures of blood pressure and hypertension

artículo científico publicado en 2015

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

artículo científico publicado en 2014

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A parallel SNP array study of genomic aberrations associated with mental retardation in patients and general population in Estonia

artículo científico publicado en 2010

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A variant in MCF2L is associated with osteoarthritis

artículo científico publicado en 2011

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

artículo científico publicado en 2015

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

artículo científico publicado en 2020

Altered Gene Expression Associated with microRNA Binding Site Polymorphisms

artículo científico publicado en 2015

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

artículo científico publicado en 2016

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

An epigenome-wide association study meta-analysis of educational attainment.

artículo científico publicado en 2017

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

artículo científico publicado en 2019

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

artículo científico publicado en 2016

Analytical strategies to include the X-chromosome in variance heterogeneity analyses: Evidence for trait-specific polygenic variance structure

artículo científico publicado en 2019

Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence

artículo científico publicado en 2016

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

artículo científico publicado en 2014

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

artículo científico publicado en 2013

Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts

scientific article published on 02 December 2020

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

artículo científico publicado en 2019

Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

artículo científico publicado en 2018

Autosomal genetic control of human gene expression does not differ across the sexes

artículo científico publicado en 2016

Biological interpretation of genome-wide association studies using predicted gene functions

artículo científico publicado en 2015

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

artículo científico publicado en 2014

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Cell specific eQTL analysis without sorting cells

Circulating glucuronic acid predicts healthspan and longevity in humans and mice

artículo científico publicado en 2019

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

artículo científico publicado en 2014

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

scientific journal article

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published September 2018 in Neuron

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

artículo científico publicado en 2014

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants in KCNN3 are associated with lone atrial fibrillation

artículo científico publicado en 2010

Common variants in Mendelian kidney disease genes and their association with renal function

artículo científico publicado en 2013

Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations

artículo científico publicado en 2019

Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation

artículo científico publicado en 2019

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

artículo científico publicado en 2022

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

artículo científico publicado en 2016

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression

artículo científico publicado en 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

artículo científico publicado en 2016

Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer

artículo científico publicado en 2014

Correction: Genetic Structure of Europeans: A View from the North–East.

artículo científico publicado en 2010

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

artículo científico publicado en 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

artículo científico publicado en 2017

Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

artículo científico publicado en 2015

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

artículo científico publicado en 2021

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

article published in 2017

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

artículo científico publicado en 2018

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

artículo científico publicado en 2018

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Development and validation of two SCORE-based cardiovascular risk prediction models for Eastern Europe: a multicohort study

scientific article published on 01 September 2020

Differences in local population history at the finest level: the case of the Estonian population

artículo científico publicado en 2020

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

artículo científico publicado en 2022

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Dominance genetic variation contributes little to the missing heritability for human complex traits

artículo científico publicado en 2015

Educational Attainment and Personality Are Genetically Intertwined

artículo científico publicado en 2017

Educational attainment and personality are genetically intertwined

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

artículo científico publicado en 2015

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

artículo científico publicado en 2016

Evidence of inbreeding depression on human height

artículo científico publicado en 2012

Evolutionary and functional impact of common polymorphic inversions in the human genome

artículo científico publicado en 2019

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

artículo científico publicado en 2016

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

artículo científico publicado en 2017

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Food neophobia associates with poorer dietary quality, metabolic risk factors, and increased disease outcome risk in population-based cohorts in a metabolomics study

artículo científico publicado en 2019

Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript

artículo científico publicado en 2015

GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

artículo científico publicado en 2017

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

artículo científico publicado en 2013

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

artículo científico publicado en 2015

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations

article

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

artículo científico publicado en 2020

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis

scientific article published on 01 July 2020

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity

artículo científico publicado en 2012

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

artículo científico publicado en 2017

Genetic evidence of assortative mating in humans

scholarly article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic influence on social outcomes during and after the Soviet era in Estonia

scholarly article by Kaili Rimfeld et al published April 2018 in Nature Human Behaviour

Genetic insights into biological mechanisms governing human ovarian ageing

artículo científico publicado en 2021

Genetic structure of Europeans: a view from the North-East

artículo científico publicado en 2009

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

artículo científico publicado en 2015

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

artículo científico publicado en 2016

Genetic variants in RBFOX3 are associated with sleep latency

artículo científico publicado en 2016

Genetic variants linked to education predict longevity

artículo científico publicado en 2016

Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

artículo científico publicado en 2014

Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records

scientific article published on 12 November 2018

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

artículo científico publicado en 2015

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

artículo científico publicado en 2015

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy

artículo científico publicado en 2020

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

artículo científico publicado en 2016

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

artículo científico publicado en 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

artículo científico publicado en 2018

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

artículo científico publicado en 2022

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

artículo científico publicado en 2019

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

artículo científico publicado en 2017

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.

artículo científico publicado en 2016

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and functional follow-up reveals new loci for kidney function

artículo científico publicado en 2012

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss

artículo científico publicado en 2022

Genome-wide association study identifies 30 loci associated with bipolar disorder.

artículo científico publicado en 2019

Genome-wide association study identifies 48 common genetic variants associated with handedness

artículo científico publicado en 2020

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

artículo científico publicado en 2019

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

artículo científico publicado en 2015

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

artículo científico publicado en 2021

Genome-wide association study of serum coenzyme Q10 levels identifies susceptibility loci linked to neuronal diseases

artículo científico publicado en 2016

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

artículo científico publicado en 2015

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

artículo científico publicado en 2014

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL

scientific journal article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

artículo científico publicado en 2016

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

artículo científico publicado en 2017

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

article

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

artículo científico publicado en 2020

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

artículo científico publicado en 2021

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

artículo científico publicado en 2017

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

Genotype-covariate interaction effects and the heritability of adult body mass index

artículo científico publicado en 2017

Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants

artículo científico publicado en 2020

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

artículo científico publicado en 2020

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

scholarly article by Alicia R Martin et al published 3 May 2018 in American Journal of Human Genetics

Haplotype phasing and inheritance of copy number variants in nuclear families

artículo científico publicado en 2015

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

artículo científico publicado en 2016

Hemani et al. reply

artículo científico publicado en 2014

Hidden heritability due to heterogeneity across seven populations

artículo científico publicado en 2017

History of the Diagnosis of a Sexually Transmitted Disease is Linked to Normal Variation in Personality Traits

Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

artículo científico publicado en 2013

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

artículo científico publicado en 2019

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

artículo científico publicado en 2012

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

artículo científico publicado el 3 de julio de 2012

Identification of seven loci affecting mean telomere length and their association with disease

artículo científico publicado en 2013

Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel

artículo científico publicado en 2017

Improved polygenic prediction by Bayesian multiple regression on summary statistics

scientific article published on 08 November 2019

Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome

artículo científico publicado en 2020

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

artículo científico publicado en 2012

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

artículo científico publicado en 2022

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

artículo científico publicado en 2012

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

artículo científico publicado en 2017

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Longevity candidate genes and their association with personality traits in the elderly

artículo científico publicado en 2011

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

artículo científico publicado en 2022

Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians

artículo científico publicado en 2014

Mendelian randomization study of height and risk of colorectal cancer

artículo científico publicado en 2015

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

artículo científico publicado en 2012

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance

artículo científico publicado en 2014

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

artículo científico publicado en 2015

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

artículo científico publicado en 2015

Metabolomic profiles as reliable biomarkers of dietary composition

artículo científico publicado en 2017

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

artículo científico publicado en 2011

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

artículo científico publicado en 2017

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

Molecular genetic overlap between migraine and major depressive disorder

scholarly article by Yuanhao Yang et al published 11 July 2018 in European Journal of Human Genetics

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

artículo científico publicado en 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

artículo científico publicado en 2019

Multi-ethnic genome-wide association study for atrial fibrillation

article

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New gene functions in megakaryopoiesis and platelet formation

artículo científico publicado en 2011

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

artículo científico publicado en 2014

PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data

artículo científico publicado en 2019

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

artículo científico publicado en 2014

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

artículo científico publicado en 2017

Personality traits and eating habits in a large sample of Estonians

artículo científico publicado en 2012

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

scientific article published on 10 June 2019

Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases

artículo científico publicado en 2020

Population genetic differentiation of height and body mass index across Europe

artículo científico publicado en 2015

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

artículo científico publicado en 2018

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

artículo científico publicado en 2020

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quality control and conduct of genome-wide association meta-analyses

artículo científico publicado en 2014

RETRACTED ARTICLE: Detection and replication of epistasis influencing transcription in humans

retracted scholarly article

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

Rare coding variants in ten genes confer substantial risk for schizophrenia

artículo científico publicado en 2022

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity

artículo científico publicado en 2013

Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia

artículo científico publicado en 2018

Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions

artículo científico publicado en 2012

RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations

artículo científico publicado en 2013

Replicability and robustness of genome-wide-association studies for behavioral traits

artículo científico publicado en 2014

Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'.

artículo científico publicado en 2018

Retraction Note: Detection and replication of epistasis influencing transcription in humans

artículo científico publicado en 2021

Roadmap for a precision-medicine initiative in the Nordic region

artículo científico publicado en 2019

SNP-Based Heritability Estimates of Common and Specific Variance in Self- and Informant-Reported Neuroticism Scales

artículo científico publicado en 2016

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

artículo científico publicado en 2016

Self-Other Agreement in Happiness and Life-Satisfaction: The Role of Personality Traits

scholarly article by Henrik Dobewall et al published 27 September 2012 in Social Indicators Research

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

artículo científico publicado en 2010

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Sex- and age-interacting eQTLs in human complex diseases

artículo científico publicado en 2013

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

artículo científico publicado en 2022

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

artículo científico publicado en 2020

Signatures of negative selection in the genetic architecture of human complex traits

artículo científico publicado en 2018

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity

artículo científico publicado en 2015

Structural genomic variation as risk factor for idiopathic recurrent miscarriage

artículo científico publicado en 2014

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells

artículo científico publicado en 2015

Testing the role of predicted gene knockouts in human anthropometric trait variation

artículo científico publicado en 2016

The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males

artículo científico publicado en 2013

The Genetic Architecture of Gene Expression in Peripheral Blood

artículo científico publicado en 2017

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Polygenic and Monogenic Basis of Blood Traits and Diseases

artículo científico publicado en 2020

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects

artículo científico publicado en 2015

The effect of LRRK2 loss-of-function variants in humans

artículo científico publicado en 2020

The effect of X-linked dosage compensation on complex trait variation

scientific article published on 08 July 2019

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The individual and global impact of copy-number variants on complex human traits

artículo científico publicado en 2022

The relationship between the Five-Factor Model personality traits and peptic ulcer disease in a large population-based adult sample

artículo científico publicado en 2015

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The transcriptional landscape of age in human peripheral blood

artículo científico publicado en 2015

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

artículo científico publicado en 2010

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

artículo científico publicado en 2020

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

artículo científico publicado en 2016

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Variance determines self-observer agreement on the Big Five personality traits

article published in 2010

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

artículo científico publicado en 2016

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression.

artículo científico publicado en 2013

Widespread signatures of negative selection in the genetic architecture of human complex traits

scholarly article published 3 June 2017

Within-trait heterogeneity in age group differences in personality domains and facets: implications for the development and coherence of personality traits

artículo científico publicado en 2015

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