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Lista de obras de Clive Page

A Non Anti-coagulant Fraction of Heparin Inhibits Leukocyte Diapedesis into the Lung by an Effect on Platelets

scientific article published on 15 May 2016

A biochemical and functional assessment of monocyte phosphodiesterase activity in healthy and asthmatic subjects

scientific article published on 01 January 2000

A new model for the continuous monitoring of polymorphonuclear leukocyte trapping in the pulmonary vasculature of the rabbit

artículo científico publicado en 2002

A response to: ‘A manifesto for clinical pharmacology from principles to practice’ by Jeff Aronson

artículo científico publicado el 1 de diciembre de 2010

A role for mitogen kinase kinase 3 in pulmonary inflammation validated from a proteomic approach.

artículo científico publicado en 2014

Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice

artículo científico publicado en 2006

Adenosine monophosphate is elevated in the bronchoalveolar lavage fluid of mice with acute respiratory toxicity induced by nanoparticles with high surface hydrophobicity

artículo científico publicado en 2014

Adenosine receptors and asthma.

artículo científico publicado en 2008

Airway irritability--a burning issue?

scientific article published on 20 July 2009

Allergen challenge alters lymphocyte phosphodiesterase activity in horses with heaves.

artículo científico publicado en 2004

Allergen induces the migration of platelets to lung tissue in allergic asthma

scientific article published on 20 December 2007

Alternative and/or integrative therapies for pneumonia under development.

artículo científico publicado en 2004

Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology

artículo científico publicado en 2020

Anti-adhesive glycoproteins in echinoderm mucus secretions.

artículo científico publicado en 2004

Antigen-induced bronchial hyperresponsiveness in the rabbit is not dependent on M(2)-receptor dysfunction

scientific article published on 01 January 1999

Antitussive drugs--past, present, and future

artículo científico publicado en 2014

Antitussive effect of carcainium chloride in patients with chronic cough and idiopathic interstitial pneumonias: A pilot study.

artículo científico publicado en 2016

Are phosphodiesterase 4 inhibitors just more theophylline?

artículo científico publicado en 2006

Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes

scientific article published on 27 May 2016

Bifunctional drugs for the treatment of asthma and chronic obstructive pulmonary disease.

artículo científico

Biochemical and functional assessment of equine lymphocyte phosphodiesterases and protein kinase C.

artículo científico publicado en 2004

Biochemical and functional characterization of glycosaminoglycans released from degranulating rat peritoneal mast cells: Insights into the physiological role of endogenous heparin

scientific article published on 03 November 2016

Bleomycin-induced lung injury assessed noninvasively and in spontaneously breathing rats by proton MRI

scientific article published on 01 October 2007

Bleomycin-induced lung injury in mice investigated by MRI: model assessment for target analysis

artículo científico publicado en 2011

Bradykinin and capsaicin induced airways obstruction in the guinea pig are platelet dependent

artículo científico publicado en 2015

Brain natriuretic peptide protects against hyperresponsiveness of human asthmatic airway smooth muscle via an epithelial cell-dependent mechanism

artículo científico publicado en 2014

Bronchial hyperresponsiveness induced by chronic treatment with albuterol: Role of sensory nerves.

artículo científico publicado en 2002

Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging.

artículo científico publicado en 2007

Celebrating the role of the British Pharmacological Society

artículo científico publicado en 2006

Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration

artículo científico publicado en 2010

Differential inhibition of equine neutrophil function by phosphodiesterase inhibitors.

artículo científico publicado en 2001

Doxofylline, a novofylline inhibits lung inflammation induced by lipopolysacharide in the mouse.

artículo científico publicado en 2014

Doxofylline: a "novofylline".

artículo científico publicado en 2010

Dual PDE3/4 and PDE4 inhibitors: novel treatments for COPD and other inflammatory airway diseases.

artículo científico publicado en 2014

Editorial overview: Respiratory: Cough: a burning issue.

artículo científico publicado en 2015

Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation

scientific article published on 02 December 2019

Effect of Mycobacterium tuberculosis chaperonins on bronchial eosinophilia and hyper-responsiveness in a murine model of allergic inflammation.

artículo científico publicado en 2004

Effect of antagonists for NK(2)and B(2) receptors on antigen-induced airway responses in allergic rabbits

scientific article published on 01 January 2000

Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study

artículo científico publicado en 2017

Effect of heparin on antigen-induced airway responses and pulmonary leukocyte accumulation in neonatally immunized rabbits.

artículo científico publicado en 2000

Effect of lipopolysaccharide on the responsiveness of equine bronchial tissue

artículo científico publicado en 2018

Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses

artículo científico publicado en 2007

Effect of the K+(ATP) channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits.

artículo científico publicado en 2004

Effect of the Mixed Phosphodiesterase 3/4 Inhibitor RPL554 on Human Isolated Bronchial Smooth Muscle Tone

artículo científico publicado en 2013

Effects of heparin and related drugs on neutrophil function

artículo científico publicado en 2012

Effects of heparin and related molecules upon neutrophil aggregation and elastase release in vitro.

artículo científico publicado en 2003

Effects of neuraminidase on equine isolated bronchi.

artículo científico publicado en 2008

Effects of tetrandrine on growth factor-induced DNA synthesis and proliferative response of rat pulmonary artery smooth muscle cells.

artículo científico publicado en 2000

Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials

artículo científico publicado en 2013

Elevated expression of adenosine A1 receptor in bronchial biopsy specimens from asthmatic subjects.

artículo científico publicado en 2007

Emerging anti-inflammatory strategies for COPD

artículo científico publicado el 10 de abril de 2012

Evaluation of the effects of the R- and S-enantiomers of salbutamol on equine isolated bronchi

artículo científico publicado en 2010

Evidence to suggest that the phosphodiesterase 4 isoenzyme is present and involved in the proliferation of umbilical cord blood mononuclear cells

article

Extracellular matrix composition influences the resistance of airway remodelling events towards glucocorticoid treatment

artículo científico publicado el 1 de abril de 2003

Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity

artículo científico publicado en 2014

Getting to the heart of asthma: can "beta blockers" be useful to treat asthma?

artículo científico publicado en 2007

Gustav Born: pioneer in imaging platelet and leukocyte biology

artículo científico publicado en 2018

Heparanase induces inflammatory cell recruitment in vivo by promoting adhesion to vascular endothelium

artículo científico publicado en 2014

Heparin and related drugs: beyond anticoagulant activity.

artículo científico publicado en 2013

Heparin and structurally related polymers attenuate eotaxin-1 (CCL11) release from human airway smooth muscle.

artículo científico publicado en 2008

Heparin inhibits allergen-induced eosinophil infiltration into guinea-pig lung via a mechanism unrelated to its anticoagulant activity.

artículo científico publicado en 2001

High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.

artículo científico publicado en 2012

Human embryonic stem cells and lung regeneration

scientific article published on 25 August 2008

Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects

artículo científico publicado en 2001

Identification with MRI of the pleura as a major site of the acute inflammatory effects induced by ovalbumin and endotoxin challenge in the airways of the rat

artículo científico publicado en 2006

Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV)1 and sensory neuropeptides in the guinea-pig respiratory system

artículo científico publicado en 2006

Immunohistochemical localization of transient receptor potential vanilloid subtype 1 in the trachea of ovalbumin-sensitized Guinea pigs

scientific article published on 27 May 2008

Immunohistochemical localization of vanilloid receptor subtype 1 (TRPV1) in the guinea pig respiratory system.

artículo científico publicado en 2005

Impact of erdosteine on chronic bronchitis and COPD: A meta-analysis

artículo científico publicado en 2017

In Vitro Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines.

artículo científico publicado en 2015

Inhaled nebulised unfractionated heparin improves lung function in moderate to very severe COPD: A pilot study

artículo científico publicado en 2017

Insights on animal models to investigate inhalation therapy: Relevance for biotherapeutics.

artículo científico publicado en 2017

Interaction of Formulation and Device Factors Determine the In Vitro Performance of Salbutamol Sulphate Dry Powders for Inhalation.

artículo científico publicado en 2015

LPS-induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-Selectin

scientific article published on 01 August 2019

Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y1 and P2Y14 receptors in mice.

artículo científico publicado en 2017

Locally available heparin modulates inflammatory cell recruitment in a manner independent of anticoagulant activity.

artículo científico publicado en 2009

Lung inflammation does not affect the clearance kinetics of lipid nanocapsules following pulmonary administration.

artículo científico publicado en 2016

Markers of disease severity in chronic obstructive pulmonary disease.

artículo científico publicado en 2005

Markers of exacerbation severity in chronic obstructive pulmonary disease

artículo científico publicado en 2006

Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.

artículo científico publicado en 2006

Mycobacterium tuberculosis chaperonin 60.1 inhibits leukocyte diapedesis in a murine model of allergic lung inflammation

artículo científico publicado en 2012

Neutrophil and platelet activation in equine recurrent airway obstruction is associated with increased neutrophil CD13 expression, but not platelet CD41/61 and CD62P or neutrophil-platelet aggregate formation.

artículo científico publicado en 2009

Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI

artículo científico publicado en 2011

Novel approaches to the treatment of pneumonia.

artículo científico publicado en 2003

Novel bronchodilators for the treatment of chronic obstructive pulmonary disease

artículo científico publicado el 16 de junio de 2011

Novel pharmacological approaches to airway and pulmonary vascular disease

artículo científico publicado en 2009

Outcomes for COPD pharmacological trials: from lung function to biomarkers.

artículo científico publicado en 2008

Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs.

artículo científico publicado en 2016

PDE inhibitors currently in early clinical trials for the treatment of asthma

artículo científico

Paradoxical pharmacology: turning our pharmacological models upside down

artículo científico publicado el 31 de marzo de 2011

Peripheral mechanisms II: the pharmacology of peripherally active antitussive drugs.

artículo científico publicado en 2009

Pharmacokinetic considerations concerning the use of bronchodilators in the treatment of chronic obstructive pulmonary disease

artículo científico publicado en 2018

Pharmacological Modulation of the Inflammatory Actions of Platelets

artículo científico publicado el 1 de enero de 2012

Pharmacological characterization of adenosine receptors on isolated human bronchi

artículo científico publicado en 2011

Pharmacology and Therapeutics of Bronchodilators

artículo científico publicado el 18 de mayo de 2012

Pharmacology of Heparin and Related Drugs

artículo científico

Phosphodiesterase activity in neutrophils from horses with chronic obstructive pulmonary disease

scientific article published on 01 October 2000

Phosphodiesterase inhibitors in the treatment of inflammatory diseases.

artículo científico publicado en 2011

Phosphodiesterase inhibitors.

artículo científico publicado en 2006

Phosphodiesterase isoenzymes in equine platelets and their influence on platelet adhesion

artículo científico publicado en 2007

Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation

artículo científico publicado en 2004

Platelet activation in asthma: integral to the inflammatory response

scientific article published on 01 April 2006

Platelet activation in ponies with airway inflammation

artículo científico publicado en 2007

Platelets Play a Central Role in Sensitization to Allergen.

artículo científico publicado en 2018

Platelets and allergic inflammation.

artículo científico publicado en 2014

Platelets are essential for leukocyte recruitment in allergic inflammation.

artículo científico publicado en 2003

Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation

artículo científico publicado en 2003

Platelets coming of age: implications for our understanding of allergic inflammation.

artículo científico publicado en 2013

Polyvalent mechanical bacterial lysate for the prevention of recurrent respiratory infections: a meta-analysis.

artículo científico publicado en 2011

Preclinical evaluation of an inhibitor of cytosolic phospholipase A2α for the treatment of asthma

artículo científico publicado en 2011

Predicting the Fine Particle Fraction of Dry Powder Inhalers Using Artificial Neural Networks.

artículo científico publicado en 2016

Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin

scientific article published on 01 May 2000

Protective effect of a PAR2-activating peptide on histamine-induced bronchoconstriction in guinea-pig

artículo científico publicado en 2001

Pulmonary biomarkers in chronic obstructive pulmonary disease.

artículo científico publicado en 2006

Quantitative assessment of nanoparticle surface hydrophobicity and its influence on pulmonary biocompatibility

artículo científico publicado en 2014

RSD931, a novel anti-tussive agent acting on airway sensory nerves

artículo científico publicado en 2003

Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse

artículo científico publicado en 2008

Relationship of airway responsiveness with airway morphometry in normal and immunized rabbits.

artículo científico publicado en 2001

Role of sex hormones in allergic inflammation in mice

artículo científico publicado en 2007

Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent

artículo científico publicado en 2006

Selective PDE inhibitors as novel treatments for respiratory diseases.

artículo científico publicado en 2012

Sex differences in the influence of obesity on a murine model of allergic lung inflammation

scientific article published on 06 December 2019

Some structural determinants of the antiproliferative effect of heparin-like molecules on human airway smooth muscle

artículo científico publicado en 2005

Steroid sparing effects of doxofylline

artículo científico publicado en 2017

Stimulation of airway sensory nerves by cyclosporin A and FK506 in guinea-pig isolated bronchus.

artículo científico publicado en 1998

Structural characterization and anti-inflammatory activity of two novel polysaccharides from the sea squirt, Ascidiella aspersa

artículo científico publicado en 2016

TNF‐α‐induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways

artículo científico publicado el 1 de marzo de 2012

Targeting Mechanisms Linking COPD to Type 2 Diabetes Mellitus

artículo científico publicado en 2017

The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections

artículo científico publicado en 2016

The effect of anti-integrin monoclonal antibodies on antigen-induced pulmonary inflammation in allergic rabbits.

artículo científico publicado en 2003

The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough.

artículo científico publicado en 2015

The effects of heparin and related molecules on vascular permeability and neutrophil accumulation in rabbit skin.

artículo científico publicado en 2002

The effects of heparin and related molecules upon the adhesion of human polymorphonuclear leucocytes to vascular endothelium in vitro.

artículo científico publicado en 2000

The effects of heparin on the adhesion of human peripheral blood mononuclear cells to human stimulated umbilical vein endothelial cells.

artículo científico publicado en 2001

The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways

artículo científico publicado en 2001

The future challenges facing the development of new antimicrobial drugs.

artículo científico publicado en 2002

The mechanism of action of doxofylline is unrelated to HDAC inhibition, PDE inhibition or adenosine receptor antagonism

artículo científico publicado el 25 de noviembre de 2011

The pharmacology of two novel long-acting phosphodiesterase 3/4 inhibitors, RPL554 [9,10-dimethoxy-2(2,4,6-trimethylphenylimino)-3-(n-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one] and RPL565 [6,7-dihydro-2-(2,6-diis

artículo científico publicado en 2006

The rabbit as a model to study asthma and other lung diseases

artículo científico publicado en 2008

The role of CD23 on allergen-induced IgE levels, pulmonary eosinophilia and bronchial hyperresponsiveness in mice

artículo científico publicado en 2000

The role of adenosine receptors in the action of theophylline on human peripheral blood mononuclear cells from healthy and asthmatic subjects.

artículo científico publicado en 2000

The role of biomarkers in respiratory disease

artículo científico publicado el 1 de diciembre de 2010

The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus

artículo científico publicado en 2015

The role of platelets in the pathophysiology of asthma.

artículo científico publicado en 2007

The role of proteoglycans in the regulation of airways inflammation and airways remodelling.

artículo científico publicado en 2000

The role of sensory nerves in propranolol-induced bronchial hyperresponsiveness in the guinea-pig

artículo científico publicado en 1999

The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study

artículo científico publicado en 2007

The scientific legacy of Sir James W. Black.

artículo científico publicado en 2011

Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France

artículo científico publicado en 2016

Uncharged nucleoside inhibitors of β-1,4-galactosyltransferase with activity in cells

artículo científico publicado en 2016

Use of indacaterol for the treatment of COPD: a pharmacokinetic evaluation.

artículo científico

Use of within-group designs to test anti-tussive drugs in conscious guinea-pigs.

artículo científico publicado en 2010

Using Salt Counterions to Modify β2-Agonist Behavior in Vivo.

artículo científico publicado en 2016

Validating 123I-metaiodobenzylguanidine as a platelet marker for non-invasive imaging in rabbits

artículo científico publicado en 2010