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Lista de obras de Steve Humphries

A Common Mutation in the Lipoprotein Lipase Gene Promoter, −93T/G, Is Associated With Lower Plasma Triglyceride Levels and Increased Promoter Activity In Vitro ⬇️

artículo científico publicado el 1 de octubre de 1997

A double heterozygote for familial hypercholesterolaemia and familial defective apolipoprotein B-100.

artículo científico publicado en 2010

A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium

artículo científico publicado en 2011

A gene-centric study of common carotid artery remodelling

artículo científico publicado en 2012

A genetic instrument for Mendelian randomization of fibrinogen.

artículo científico publicado en 2012

A genome-wide association study identifies multiple loci for variation in human ear morphology

artículo científico publicado en 2015

A priori-defined Mediterranean-like dietary pattern predicts cardiovascular events better in north Europe than in Mediterranean countries

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

artículo científico publicado en 2014

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima–media thickness)

article

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

artículo científico publicado en 2014

A variant in LDLR is associated with abdominal aortic aneurysm

scientific journal article

ANGPTL4 E40K and T266M: effects on plasma triglyceride and HDL levels, postprandial responses, and CHD risk

artículo científico publicado en 2008

APOE, CETP and LPL genes show strong association with lipid levels in Greek children

artículo científico publicado en 2009

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men

artículo científico publicado en 2010

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

artículo científico publicado en 2011

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

An analysis of drug modulation of abdominal aortic aneurysm growth through 25 years of surveillance

article

An association between arterial pulse pressure and variation in the fibrillin-1 gene ⬇️

artículo científico publicado el 1 de octubre de 1997

Analysis of the Association of A Heat Shock Protein70‐1 Gene Promoter Polymorphism With Myocardial Infarction and Coronary Risk Traits ⬇️

artículo científico publicado el 1 de febrero de 1998

Analysis of the frequency and spectrum of mutations recognised to cause familial hypercholesterolaemia in routine clinical practice in a UK specialist hospital lipid clinic

artículo científico publicado en 2013

Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease

artículo científico publicado en 2015

Angiotensin-converting enzyme D allele does not influence susceptibility to acute hypoxic respiratory failure in children

scientific article published on 12 September 2008

Angiotensin-converting enzyme genotype and late respiratory complications of mustard gas exposure

artículo científico publicado en 2008

Antibodies to citrullinated peptides and risk of coronary heart disease

artículo científico publicado en 2013

Apal polymorphism in insulin-like growth factor II (IGF2) gene and weight in middle-aged males ⬇️

artículo científico publicado el 1 de septiembre de 1997

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study

artículo científico publicado en 2006

Apolipoprotein B signal peptide and apolipoprotein E genotypes as determinants of the hepatic secretion of VLDL apoB in obese men ⬇️

artículo científico publicado el 1 de septiembre de 1998

Apolipoprotein C-lll gene variation and dyslipidaemia ⬇️

artículo científico publicado el 1 de junio de 1997

Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals

artículo científico publicado en 2013

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

artículo científico publicado en 2012

Applicability of LDLR flanking microsatellite polymorphisms for prenatal diagnosis of homozygous state for familial hypercholesterolemia ⬇️

artículo científico publicado el 1 de mayo de 1998

Application of recombinant DNA technology to prenatal detection of inherited defects ⬇️

artículo científico publicado el 1 de octubre de 1983

Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.

artículo científico publicado en 2010

Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm

article

Association between IL6 gene variants -174G>C and -572G>C and serum IL-6 levels: interactions with social position in the Whitehall II cohort

artículo científico publicado en 2008

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association between periodontitis and common variants in the promoter of the interleukin-6 gene

article

Association between short leukocyte telomere length, endotoxemia, and severe periodontitis in people with diabetes: a cross-sectional survey

artículo científico publicado en 2014

Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus

artículo científico publicado en 2009

Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus

article

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease

scientific article published on 12 December 2013

Association of TLL1 gene polymorphism (rs1503298, T > C) with coronary heart disease in PREDICT, UDACS and ED cohorts

artículo científico publicado en 2014

Association of a sequence variant in DAB2IP with coronary heart disease

artículo científico publicado en 2011

Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies.

artículo científico publicado en 2018

Association of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques

Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation

artículo científico publicado en 2009

Association of the PGC-1α rs8192678 variant with microalbuminuria in subjects with type 2 diabetes mellitus

artículo científico publicado en 2012

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Associations between lipoprotein lipase gene polymorphisms and plasma correlations of lipids, lipoproteins and lipase activities in young myocardial infarction survivors and age-matched healthy individuals from Sweden

artículo científico publicado el 1 de diciembre de 1992

Awareness of lifestyle risk factors for cancer and heart disease among adults in the UK.

artículo científico publicado en 2008

Bayesian meta-analysis of genetic association studies with different sets of markers

scientific article published on April 2008

Blood pressure loci identified with a gene-centric array

artículo científico publicado en 2011

Body fat distribution in relation to smoking and exogenous hormones in British women

artículo científico publicado en 2012

Bone structure and geometry in young men: the influence of smoking, alcohol intake and physical activity

artículo científico publicado en 2012

C-reactive protein and coronary heart disease: predictive test or therapeutic target?

artículo científico publicado en 2008

C-reactive protein gene variant and the human left ventricular growth response to exercise: data from The LARGE Heart Study

artículo científico publicado en 2010

Candidate-Gene Studies of the Atherogenic Lipoprotein Phenotype: A Sib-Pair Linkage Analysis of DZ Women Twins ⬇️

artículo científico publicado el 1 de febrero de 1998

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

artículo científico publicado en 2017

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

artículo científico publicado en 2012

Characterization of DNA-binding proteins using multiplexed competitor EMSA

artículo científico publicado en 2009

Characterization of a new apolipoprotein E5 variant detected in two French-Canadian subjects ⬇️

artículo científico publicado el 1 de abril de 1991

Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk

artículo científico publicado en 2012

Chromatin structure of the 5S ribonucleic acid genes of Xenopus laevis ⬇️

artículo científico publicado el 24 de julio de 1979

ClinVar database of global familial hypercholesterolemia-associated DNA variants

artículo científico publicado en 2018

Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

artículo científico publicado en 2015

Clinical signs of familial hypercholesterolemia in patients with familial defective apolipoprotein B-100 and normal low density lipoprotein receptor function ⬇️

artículo científico publicado el 1 de mayo de 1991

Clinical utility gene card for: hyperlipoproteinemia, TYPE II.

artículo científico publicado en 2013

Commentary PCSK9 variants: A new database

artículo científico publicado en 2009

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease

artículo científico publicado en 2014

Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study

scholarly article by Alexander P. Reiner et al published July 2005 in Atherosclerosis

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

artículo científico publicado en 2011

Comparison of coronary heart disease genetic assessment with conventional cardiovascular risk assessment in primary care: reflections on a feasibility study

artículo científico publicado en 2015

Coronary heart disease risk prediction in the era of genome-wide association studies: current status and what the future holds

scientific article published on May 2010

Correction: Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

artículo científico publicado en 2015

Correction: Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.

artículo científico publicado en 2013

Corrigendum to “Interleukin 18 and coronary heart disease: Prospective study and systematic review” [Atherosclerosis 217 (2011) 227–233].

artículo científico publicado en 2011

CpG-PCR combined with sample pooling and mutant enrichment for CpG mutation screening in population studies ⬇️

artículo científico publicado el 1 de enero de 1998

Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts

artículo científico publicado en 2008

Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study

artículo científico publicado en 2009

Cytokine and cytokine receptor gene polymorphisms and their functionality.

artículo científico publicado en 2008

DNA polymorphisms of the apolipoprotein B gene in Chinese coronary artery disease patients

artículo científico publicado el 1 de octubre de 1992

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Demonstration of the presence of the "deleted" MIR122 gene in HepG2 cells

artículo científico publicado en 2015

Denaturing Gradient Gel Electrophoretic Analysis of Codons 3456–3553 of the Apolipoprotein-B Gene in 106 Type 11a Hyperlipoproteinaemic Individuals ⬇️

artículo científico publicado el 1 de enero de 1998

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study

artículo científico publicado en 2008

Duration of preceding hypertension is associated with prolonged length of ICU stay

artículo científico publicado en 2010

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Editor in Chief's Report for Atherosclerosis for 2011 ⬇️

artículo científico publicado el 16 de noviembre de 2011

Editor in Chief's report for Atherosclerosis for 2013.

artículo científico publicado en 2013

Editor's annual report

artículo científico publicado en 2009

Editor's report

Editor-in-Chief's report 2014

Editor-in-Chief's report 2015

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials

artículo científico publicado en 2011

Effect of six type II diabetes susceptibility loci and an FTO variant on obesity in Pakistani subjects.

artículo científico publicado en 2015

Effect of the PPARG2 Pro12Ala Polymorphism on Associations of Physical Activity and Sedentary Time with Markers of Insulin Sensitivity in Those with an Elevated Risk of Type 2 Diabetes

artículo científico publicado en 2015

Effectiveness of a self-management intervention with personalised genetic and lifestyle-related risk information on coronary heart disease and diabetes-related risk in type 2 diabetes (CoRDia): study protocol for a randomised controlled trial

artículo científico publicado en 2015

Effects of genetic variation on chromatin structure and the transcriptional machinery: analysis of the IL6 gene locus ⬇️

artículo científico publicado el 16 de agosto de 2012

Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding

artículo científico publicado en 2008

Electrophoresis for genoptyping:temporal thermal gradient gel electrophoreisis for profiling of oiligonucleotide dissociation ⬇️

artículo científico publicado el 11 de julio de 1995

Erratum: A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

artículo científico publicado en 2015

European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice ...

artículo científico publicado en 2007

European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by rep

artículo científico publicado en 2007

Expression of Matrix Metalloproteinases and Their Inhibitor TIMP-1 in the Rat Carotid Artery After Balloon Injury ⬇️

artículo científico publicado el 1 de septiembre de 1997

FH‐Pyrgos: a novel mutation in the promoter (−45delT) of the low‐density lipoprotein receptor gene associated with familial hypercholesterolemia ⬇️

artículo científico publicado el 1 de noviembre de 2003

FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

artículo científico publicado en 2009

Familial defective apolipoprotein B-100: a single mutation that causes hypercholesterolemia and premature coronary artery disease

artículo científico publicado el 1 de octubre de 1992

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

artículo científico publicado en 2015

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society

artículo científico publicado en 2013

Familial hypercholesterolaemia: a pressing issue for European health care

artículo científico

Familial hypercholesterolaemia: summary of NICE guidance

scientific article published in the British Medical Journal

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

artículo científico publicado en 2011

Free protein S level as a risk factor for coronary heart disease and stroke in a prospective cohort study of healthy United Kingdom men.

artículo científico publicado en 2011

Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant

artículo científico publicado en 2015

Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.

artículo científico publicado en 2017

Functional analysis of TCF7L2 genetic variants associated with type 2 diabetes ⬇️

artículo científico publicado el 7 de marzo de 2012

Functional analysis of four LDLR 5'UTR and promoter variants in patients with familial hypercholesterolaemia

artículo científico publicado en 2014

Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels

artículo científico publicado en 2012

GPs have key role in detecting familial hypercholesterolaemia

artículo científico publicado en 2011

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

artículo científico publicado en 2018

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb

artículo científico publicado en 2015

Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers

article

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

artículo científico publicado en 2013

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

artículo científico publicado en 2009

Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.

artículo científico publicado en 2012

Genetic analysis of NR0B1 in congenital adrenal hypoplasia patients: identification of a rare regulatory variant resulting in congenital adrenal hypoplasia and hypogonadal hypogonadism without testicular carcinoma in situ.

artículo científico publicado en 2012

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease

artículo científico publicado en 2016

Genetic relationship between the 3'-VNTR and diallelic apolipoprotein B gene polymorphisms: haplotype analysis in individuals of European and south Asian origin

artículo científico publicado el 1 de enero de 1992

Genetic risk factors and Mendelian randomization in cardiovascular disease

artículo científico

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

artículo científico publicado en 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals

artículo científico publicado en 2010

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts

artículo científico publicado en 2009

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genome wide association studies of abdominal aortic aneurysms-biological insights and potential translation applications

artículo científico publicado en 2011

Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort

artículo científico publicado en 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic research to identify novel pathways in the development of abdominal aortic aneurysm

artículo científico publicado en 2012

Guidelines for the identification and management of patients with familial hypercholesterolaemia (FH): Are we coming to a consensus? ⬇️

artículo científico publicado el 1 de octubre de 2011

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

artículo científico publicado en 2014

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

artículo científico publicado en 2010

High-throughput method for determination of apolipoprotein E genotypes with use of restriction digestion analysis by microplate array diagonal gel electrophoresis ⬇️

artículo científico publicado el 1 de noviembre de 1995

Higher IL-6 levels but not IL6 -174G>C or -572G>C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery

artículo científico publicado en 2008

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

artículo científico publicado en 2014

Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo

artículo científico publicado en 2013

Human genetic evidence for involvement of CD137 in atherosclerosis

artículo científico publicado en 2014

Hyperlipidaemia associated with genetic variation in the apolipoprotein B gene ⬇️

artículo científico publicado el 1 de agosto de 1995

IL-6 polymorphisms: a useful genetic tool for inflammation research?

artículo científico publicado en 2013

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

artículo científico publicado en 2006

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.

artículo científico publicado en 2011

Identification and management of familial hypercholesterolaemia: what does it mean to primary care?

artículo científico publicado en 2009

Identification of a common low density lipoprotein receptor mutation (C163Y) in the west of Scotland ⬇️

artículo científico publicado el 1 de julio de 1998

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

artículo científico publicado en 2017

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

artículo científico publicado en 2012

Identifying functional noncoding variants from genome-wide association studies for cardiovascular disease and related traits.

artículo científico publicado en 2015

Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach

artículo científico publicado en 2014

Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene

artículo científico publicado en 2017

Identifying patients with familial hypercholesterolaemia in primary care

artículo científico publicado en 2008

Improving detection of familial hypercholesterolaemia in primary care using electronic audit and nurse-led clinics

artículo científico publicado en 2015

Improving identification of familial hypercholesterolaemia in primary care: derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT).

artículo científico publicado en 2014

Improving the cost-effectiveness equation of cascade testing for familial hypercholesterolaemia

artículo científico publicado en 2015

Increased C-reactive protein levels in overweight and obese women taking exogenous hormones: the United Kingdom Women's Heart Study (UKWHS).

artículo científico publicado en 2009

Increased levels of circulating fatty acids are associated with protective effects against future cardiovascular events in non-diabetics

artículo científico publicado en 2017

Indices of obesity and cardiovascular risk factors in British women.

artículo científico publicado en 2008

Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents.

artículo científico publicado en 2012

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

artículo científico publicado en 2008

Influence of apolipoproteins on the anatomical distribution of arterial disease ⬇️

artículo científico publicado el 1 de agosto de 1991

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

artículo científico publicado en 2012

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

artículo científico publicado en 2009

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

artículo científico publicado en 2012

Interleukin 18 and coronary heart disease: prospective study and systematic review.

artículo científico publicado en 2011

Interleukin-6 receptor pathways in abdominal aortic aneurysm

scientific article published on 30 October 2012

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

artículo científico publicado en 2009

LDL oxidative modification and carotid atherosclerosis: Results of a multicenter study

artículo científico publicado en 2012

LPL promoter -93T/G transition influences fasting and postprandial plasma triglycerides response in African-Americans and Hispanics ⬇️

artículo científico publicado el 1 de junio de 1998

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Left ventricular wall thickness and the presence of asymmetric hypertrophy in healthy young army recruits: data from the LARGE heart study

artículo científico publicado en 2013

Lipoprotein association studies: taking stock and moving forward

artículo científico publicado en 2011

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men

Low-density lipoprotein receptor gene familial hypercholesterolemia variant database: update and pathological assessment

artículo científico publicado en 2012

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

artículo científico publicado en 2017

Marginal role for 53 common genetic variants in cardiovascular disease prediction

artículo científico publicado en 2016

Measurements of Carotid Intima-Media Thickness and of Interadventitia Common Carotid Diameter Improve Prediction of Cardiovascular Events

scholarly article by Damiano Baldassarre et al published October 2012 in Journal of the American College of Cardiology

Mendelian randomisation, lipids, and cardiovascular disease ⬇️

artículo científico publicado el 17 de mayo de 2012

Mendelian randomization of blood lipids for coronary heart disease

artículo científico publicado en 2014

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

artículo científico publicado en 2011

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

artículo científico publicado en 2016

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

artículo científico publicado en 2009

Multiplex MassARRAY spectrometry (iPLEX) produces a fast and economical test for 56 familial hypercholesterolaemia-causing mutations

artículo científico publicado en 2008

Multiplex ligation-dependent probe amplification analysis to screen for deletions and duplications of theLDLRgene in patients with familial hypercholesterolaemia

article

Mutation detection in Croatian patients with familial hypercholesterolemia

artículo científico publicado en 2012

Mutation detection rate and spectrum in familial hypercholesterolaemia patients in the UK pilot cascade project

artículo científico publicado en 2010

Mutation scanning by meltMADGE: validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population

artículo científico publicado en 2005

Mutation screening in patients for familial hypercholesterolaemia (ADH)

artículo científico publicado en 2009

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

Normal levels of inflammatory markers in treated patients with familial hypercholesterolaemia: a cross-sectional study

scientific article published on 30 June 2012

Novel and recurrent LDLR gene mutations in Pakistani hypercholesterolemia patients

artículo científico publicado en 2012

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels

artículo científico publicado en 2014

Out with print in with e publication: Editor in Chief's Report for Atherosclerosis for 2012 ⬇️

artículo científico publicado el 1 de enero de 2013

Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis.

artículo científico publicado en 2010

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

artículo científico publicado en 2016

PLA2G10 Gene Variants, sPLA2 Activity, and Coronary Heart Disease Risk

artículo científico publicado en 2015

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry

artículo científico publicado en 2010

Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the PREDICT study

artículo científico publicado en 2012

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

artículo científico publicado en 2016

Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

artículo científico publicado en 2017

Plasma IL-5 concentration and subclinical carotid atherosclerosis

artículo científico publicado en 2014

Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis

artículo científico publicado en 2013

Plasma fibrinogen concentration predicts the risk of myocardial infarction differently in various parts of Europe: effects of beta-fibrinogen genotype and environmental factors. The HIFMECH Study.

artículo científico publicado en 2004

Plasma lecithin:cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk

artículo científico publicado en 2011

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

artículo científico publicado en 2016

Polymorphisms in the apolipoprotein (apo) AI-CIII-AIV gene cluster: detection of genetic variation determining plasma apo AI, apo CIII and apo AIV concentrations ⬇️

artículo científico publicado el 1 de febrero de 1992

Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age

article

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

artículo científico publicado en 2013

Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.

artículo científico publicado en 2015

Progression of carotid intima-media thickness as predictor of vascular events: results from the IMPROVE study

artículo científico publicado en 2013

Psychological and behavioural impact of genetic testing smokers for lung cancer risk: a phase II exploratory trial

artículo científico publicado en 2008

Public awareness of genetic influence on chronic disease risk: are genetic and lifestyle causal beliefs compatible?

artículo científico publicado en 2010

Public health genomics and genetic test evaluation: the challenge of conducting behavioural research on the utility of lifestyle-genetic tests

artículo científico publicado en 2008

Realising the potential of the family history in risk assessment and primary prevention of coronary heart disease in primary care: ADDFAM study protocol

artículo científico publicado en 2009

Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study

artículo científico publicado en 2008

Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries

artículo científico publicado en 2014

Regarding “Analysis of risk factors for abdominal aortic aneurysm in a cohort of more than 3 million individuals”

Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men

artículo científico publicado en 2012

Response to Letter About Article, “Left Ventricular Wall Thickness and the Presence of Asymmetric Hypertrophy in Healthy Young Army Recruits: Data From the LARGE Heart Study”

scientific article published on 01 September 2013

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Segregation analysis of collagen genes in two families with joint hypermobility syndrome

artículo científico publicado el 1 de marzo de 1992

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms

artículo científico publicado en 2009

Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have an impact on aneurysmal expansion

artículo científico publicado en 2008

Serum 25-Hydroxyvitamin D Concentration in Subclinical Carotid Atherosclerosis

article

Sex hormone receptor gene variation associated with phenotype in male hypertrophic cardiomyopathy patients

article

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

artículo científico publicado en 2015

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Simplified Detection of a Mutation Causing Familial Hypercholesterolaemia Throughout Britain: Evidence for an Origin in a Common Distant Ancestor ⬇️

artículo científico publicado el 1 de marzo de 1998

Sixty-five common genetic variants and prediction of type 2 diabetes

artículo científico publicado en 2014

Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness

artículo científico publicado en 2016

Statin treatment of children with familial hypercholesterolemia--trying to balance incomplete evidence of long-term safety and clinical accountability: are we approaching a consensus?

artículo científico publicado en 2012

Statins and familial hypercholesterolaemia

artículo científico publicado en 2009

Statins for children with familial hypercholesterolemia

artículo científico publicado en 2014

Statins for children with familial hypercholesterolemia

artículo científico publicado en 2010

Statins for children with familial hypercholesterolemia

artículo científico publicado en 2007

Statins for children with familial hypercholesterolemia

artículo científico publicado en 2017

Statins for children with familial hypercholesterolemia

scientific article published on 07 November 2019

Substantial variation in qPCR measured mean blood telomere lengths in young men from eleven European countries

artículo científico publicado en 2011

Telomere length in atherosclerosis and diabetes

artículo científico publicado en 2009

Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population.

artículo científico publicado en 2014

Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors

artículo científico publicado en 2010

The Lichfield bone study: the skeletal response to exercise in healthy young men

artículo científico publicado en 2011

The UK10K project identifies rare variants in health and disease

artículo científico publicado en 2015

The Use of Recombinant DNA Technology to Study Polygenic Hyperlipidaemia ⬇️

artículo científico publicado el 1 de enero de 1984

The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects.

artículo científico publicado en 2008

The effect of pro-inflammatory conditioning and/or high glucose on telomere shortening of aging fibroblasts

artículo científico publicado en 2013

The effect of renin angiotensin system genetic variants in acute pancreatitis

artículo científico publicado en 2015

The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin

artículo científico publicado en 2012

The effects of genotype and infant weight on adult plasma levels of fibrinogen, factor VII, and LDL cholesterol are additive ⬇️

artículo científico publicado el 1 de julio de 1997

The frequency of an IL-18-associated haplotype in Africans

artículo científico publicado en 2012

The genetic architecture of the familial hyperlipidaemia syndromes: rare mutations and common variants in multiple genes

artículo científico

The genetic contribution to the risk of thrombosis and cardiovascular disease ⬇️

artículo científico publicado el 1 de enero de 1994

The genetic spectrum of familial hypercholesterolemia in Pakistan

artículo científico publicado en 2013

The genetic spectrum of familial hypercholesterolemia in south-eastern Poland

artículo científico publicado en 2015

The genetics of coronary heart disease

artículo científico

The isolation of a genomic clone containing the apolipoprotein CII gene and the detection of linkage disequilibrium between two common DNA polymorphisms around the gene ⬇️

artículo científico publicado el 1 de enero de 1984

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

artículo científico publicado en 2013

The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk

artículo científico publicado en 2010

The use of haplotypes in the identification of interaction between SNPs

artículo científico publicado en 2013

There are approximately 20 actin genes in the human genome ⬇️

artículo científico publicado el 10 de octubre de 1981

Upregulation of gingival tissue miR-200b in obese periodontitis subjects

artículo científico publicado en 2015

Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays

artículo científico publicado en 2012

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

artículo científico publicado en 2013

Use of targeted exome sequencing as a diagnostic tool for Familial Hypercholesterolaemia

artículo científico publicado en 2012

Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study

artículo científico publicado en 2010

Utility of genetic determinants of lipids and cardiovascular events in assessing risk

artículo científico publicado en 2011

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

artículo científico publicado en 2016

Variants Within TSC2 Exons 25 and 31 Are Very Unlikely to Cause Clinically Diagnosable Tuberous Sclerosis

artículo científico publicado en 2015

Variation in the uncoupling protein 2 and 3 genes and human performance

artículo científico publicado en 2012

Variation of apolipoprotein B gene is associated with myocardial infarction and lipoprotein levels in Danes ⬇️

artículo científico publicado el 1 de julio de 1991

W64R Mutation in β-3-adrenergic receptor gene and weight in a large population sample ⬇️

artículo científico publicado el 1 de abril de 1998

What is the clinical utility of DNA testing in patients with familial hypercholesterolaemia?

artículo científico publicado en 2008

Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations

artículo científico publicado en 2014

Within-individual variation in serum cholesterol levels: association with DNA polymorphisms at the apolipoprotein B and AI-CIII-AIV loci in patients with peripheral arterial disease ⬇️

artículo científico publicado el 1 de abril de 1991

Would raising the total cholesterol diagnostic cut-off from 7.5 mmol/L to 9.3 mmol/L improve detection rate of patients with monogenic familial hypercholesterolaemia?

artículo científico publicado en 2015

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