Lista de obras - Vincenzo Di Marzo - Dominio Público Uruguay

"Redundancy" of endocannabinoid inactivation: new challenges and opportunities for pain control

artículo científico publicado en 2012

'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.

artículo científico publicado en 1998

1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor

artículo científico publicado en 2014

1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 or CB2 receptor ligands

2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons.

artículo científico publicado en 2015

2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents

artículo científico publicado en 2012

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

artículo científico publicado en 2017

3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators

artículo científico publicado en 2013

<i>Mgll</i> Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota

artículo científico publicado en 2020

A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists

artículo científico publicado en 2006

A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up

artículo científico publicado en 2009

A marine mollusc provides the first example of in vivo storage of prostaglandins: Prostaglandin-1,15-lactones

artículo científico publicado en 1991

A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis

artículo científico publicado en 2015

A new strategy to block tumor growth by inhibiting endocannabinoid inactivation

artículo científico publicado en 2004

A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects

artículo científico publicado en 2013

A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons

artículo científico publicado en 2012

A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease

artículo científico publicado en 2005

A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats

artículo científico publicado en 2006

A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase

artículo científico publicado en 2004

A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid

artículo científico publicado en 2002

Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels

artículo científico publicado en 2004

Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis

artículo científico publicado en 2005

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

artículo científico publicado en 2017

Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol

artículo científico publicado en 2013

Acute neuronal injury, excitotoxicity, and the endocannabinoid system

artículo científico publicado en 2002

Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats

artículo científico publicado en 2014

Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis

artículo científico publicado en 2015

Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats

artículo científico publicado en 2008

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

artículo científico publicado en 2014

Alteration of the endocannabinoid system in mouse brain during prion disease

artículo científico publicado en 2010

Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis

scientific article published on 01 July 2019

Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance

artículo científico publicado en 2011

Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain

scientific article published on 03 April 2019

Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems.

artículo científico publicado en 2009

An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?

artículo científico publicado en 2011

An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

artículo científico publicado en 2009

An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice

artículo científico publicado en 2003

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

artículo científico publicado en 2002

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

artículo científico publicado en 1998

An introduction to the endocannabinoid system: from the early to the latest concepts

scientific article published on February 2009

Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors

artículo científico publicado en 2007

Analogues of perillaketone as highly potent agonists of TRPA1 channel.

artículo científico publicado en 2013

Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines

article

Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period

artículo científico publicado en 1999

Analysis of the “endocannabinoidome” in peripheral tissues of obese Zucker rats

scientific article published on 02 July 2013

Anandamide Uptake by Human Endothelial Cells and Its Regulation by Nitric Oxide

artículo científico publicado en 2000

Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

artículo científico publicado en 2005

Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish

artículo científico publicado en 2009

Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator

artículo científico publicado en 2015

Anandamide and other cannabimimetic fatty acid derivatives-foreword

artículo científico publicado en 2000

Anandamide as an intracellular messenger regulating ion channel activity

artículo científico publicado en 2005

Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration.

artículo científico publicado en 2015

Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB.

artículo científico publicado en 2010

Anandamide inhibits adhesion and migration of breast cancer cells

artículo científico publicado en 2005

Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.

artículo científico publicado en 2003

Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release

artículo científico publicado en 2016

Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons

artículo científico publicado en 2013

Anandamide receptors

artículo científico publicado en 2002

Anandamide – the other side of the coin

scientific article published on 01 February 2000

Anandamide, an endogenous cannabinomimetic eicosanoid: ‘Killing two birds with one stone’ ⬇️

artículo científico publicado el 1 de julio de 1995

Anandamide-derived prostamide F2α negatively regulates adipogenesis

artículo científico publicado en 2013

Anandamide-loaded nanoparticles: Preparation and characterization

artículo científico publicado en 2011

Anti-inflammatory effect of palmitoylethanolamide on human adipocytes

artículo científico publicado en 2009

Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults

artículo científico publicado en 2015

Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy

artículo científico publicado en 2013

Antithrombin Chicago, amino acid substitution of arginine 393 to histidine

artículo científico publicado en 1989

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

artículo científico publicado en 2006

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

artículo científico publicado en 2016

Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels.

artículo científico publicado en 2008

Aquatic invertebrates open up new perspectives in eicosanoid research: biosynthesis and bioactivity

artículo científico publicado en 1994

Arachidonic Acid and Eicosanoids in Hydra: Possible Endogenous Signals Involved in Chemoreception and Modulation of the Feeding Behaviour ⬇️

artículo científico publicado el 1 de enero de 1997

Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions

artículo científico publicado en 1995

Arachidonic acid, protein kinase C activators and bud formation in Hydra vulgaris

article published in 1993

Arachidonoylserotonin and Other Novel Inhibitors of Fatty Acid Amide Hydrolase ⬇️

artículo científico publicado el 30 de julio de 1998

Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

artículo científico publicado en 2015

Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis

artículo científico publicado en 2005

Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease

artículo científico publicado en 2005

Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret

artículo científico publicado en 2007

Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors

artículo científico publicado en 2002

Arylboronic acids as dual-action FAAH and TRPV1 ligands

scientific article published on 25 January 2016

At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring

artículo científico publicado en 2015

At the heart of the matter: the endocannabinoid system in cardiovascular function and dysfunction ⬇️

artículo científico publicado el 13 de abril de 2012

Attenuation of allergic contact dermatitis through the endocannabinoid system

artículo científico publicado en 2007

Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-alpha ligands in Zucker rats.

artículo científico publicado en 2009

Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence

artículo científico publicado en 2004

Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease

artículo científico publicado en 2013

Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring

artículo científico publicado en 2013

Bioactive Prenylogous Cannabinoid from Fiber Hemp (Cannabis sativa)

artículo científico publicado en 2011

Biochemistry and pharmacology of endovanilloids

artículo científico publicado en 2007

Biochemistry of the endogenous ligands of cannabinoid receptors

artículo científico publicado en 1998

Biosynthesis and Inactivation of N-Arachidonoylethanolamine (Anandamide) and N-Docosahexaenoylethanolamine in Bovine Retina

artículo científico publicado en 1999

Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation

artículo científico publicado en 1998

Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages

artículo científico publicado en 1999

Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes

artículo científico publicado en 1997

Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop.

artículo científico publicado en 2016

Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa

artículo científico publicado en 2005

Brain TRPV1: a depressing TR(i)P down memory lane?

artículo científico publicado en 2008

Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function

artículo científico publicado en 1999

CB(1) receptor antagonism: biological basis for metabolic effects

artículo científico publicado en 2008

CB1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal

artículo científico publicado en 2016

CB1 antagonists for obesity--what lessons have we learned from rimonabant?

artículo científico publicado en 2009

CB1 cannabinoid receptors and on-demand defense against excitotoxicity

artículo científico publicado en 2003

CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release

artículo científico publicado en 2013

CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides

artículo científico publicado en 2014

Cannabidiol improves vocal learning-dependent recovery from, and reduces magnitude of deficits following, damage to a cortical-like brain region in a songbird pre-clinical animal model

artículo científico publicado en 2019

Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis

artículo científico publicado en 2009

Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

artículo científico publicado en 2014

Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice

scientific article published on 14 May 2019

Cannabimovone, a Cannabinoid with a Rearranged Terpenoid Skeleton from Hemp

Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine

artículo científico publicado en 2010

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors

artículo científico publicado en 2009

Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans

artículo científico publicado en 2009

Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes.

artículo científico publicado en 2006

Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro

scientific journal article

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation

scientific journal article

Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis

artículo científico publicado en 2012

Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes

artículo científico publicado en 2011

Cannabinoids and schizophrenia: therapeutic prospects

artículo científico

Cannabinoids and the expanded endocannabinoid system in neurological disorders

scientific article published on 12 December 2019

Cannabinoids in the Treatment of Neurological Disorders

artículo científico publicado en 2015

Cannabinomimetic lipid from a marine cyanobacterium ⬇️

artículo científico publicado en 2011

Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder

artículo científico publicado en 2003

Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation

artículo científico publicado en 2007

Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system

artículo científico publicado en 2014

Cell signalling: why fasting worms age slowly

artículo científico publicado en 2011

Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration

artículo científico publicado en 2006

Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse

artículo científico publicado en 2004

Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine

artículo científico publicado en 2002

Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine

artículo científico publicado en 2004

Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors

artículo científico publicado en 2009

Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats

artículo científico publicado en 2006

Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders

artículo científico

Chemical characterisation of oxidative degradation products of Δ9-THC

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

artículo científico publicado en 2012

Chronic blockade of CB(1) receptors reverses startle gating deficits and associated neurochemical alterations in rats reared in isolation

artículo científico publicado en 2012

Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice

artículo científico publicado en 2016

Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men

artículo científico publicado en 2013

Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture

artículo científico publicado en 2015

Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis.

artículo científico publicado en 2009

Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men.

artículo científico publicado en 2007

Circulating endocannabinoids in insulin sensitive vs. insulin resistant obese postmenopausal women. A MONET group study

artículo científico publicado en 2013

Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew

artículo científico publicado en 2005

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

artículo científico publicado en 2003

Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

artículo científico publicado en 2017

Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria ⬇️

artículo científico publicado en 2015

Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease

artículo científico publicado en 2003

Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes

artículo científico publicado en 2009

Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors

artículo científico publicado en 2013

Coronary vasomotor control in obesity and morbid obesity: contrasting flow responses with endocannabinoids, leptin, and inflammation.

artículo científico publicado en 2012

Correction to Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo

scientific article published on 28 September 2020

Corrigendum to Halogenation of a capsaicin analogue leads to novel vanilloid TRPVI receptor antagonists.

artículo científico publicado en 2003

Critical role of the endogenous cannabinoid system in mouse pup suckling and growth

artículo científico publicado en 2001

DAG Lipase Involvement in Depolarization-Induced Suppression of Inhibition: Does Endocannabinoid Biosynthesis Always Meet the Demand? ⬇️

artículo científico publicado el 13 de septiembre de 2010

Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

artículo científico publicado en 2005

Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice

artículo científico publicado en 2014

Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol.

artículo científico publicado en 2006

Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa

artículo científico publicado en 2014

Desensitization of transient receptor potential vanilloid type-1 (TRPV1) channel as promising therapy of irritable bowel syndrome: characterization of the action of palvanil in the mouse gastrointestinal tract

scientific article published on 30 January 2020

Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide,

artículo científico publicado en 2016

Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists

artículo científico publicado en 2012

Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors

scientific article published on 31 May 2007

Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand

artículo científico publicado en 2011

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain

artículo científico publicado en 2016

Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo

artículo científico publicado en 2008

Development of the first potent and specific inhibitors of endocannabinoid biosynthesis

artículo científico publicado en 2006

Development of the first potential covalent inhibitors of anandamide cellular uptake

artículo científico publicado en 2006

Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential

artículo científico publicado en 2004

Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

artículo científico publicado en 2014

Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus.

artículo científico publicado en 2010

Dietary krill oil increases docosahexaenoic acid and reduces 2-arachidonoylglycerol but not N-acylethanolamine levels in the brain of obese Zucker rats

Different targets of anti-glucocorticoid treatment have been proposed, acting at supra-hypothalamic, HPA axis, glucocorticoid receptor and post-receptor levels.

artículo científico publicado en 2013

Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients

artículo científico publicado en 2010

Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain.

artículo científico publicado en 2004

Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6.

artículo científico publicado en 2014

Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands

artículo científico publicado en 2015

Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality

artículo científico publicado en 2016

Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment

artículo científico publicado en 2019

Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability

artículo científico publicado en 2012

Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors

artículo científico publicado en 2015

Dopamides, vanillylamides, ethanolamides, and arachidonic acid amides of anti-inflammatory and analgesic drug substances as TRPV1 ligands

artículo científico publicado en 2008

Dose-Specific Effects of Di-Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish

artículo científico publicado en 2017

Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response

artículo científico publicado en 2003

Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy

artículo científico publicado en 2017

Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets

artículo científico publicado en 2008

Early Low-Fat Diet Enriched With Linolenic Acid Reduces Liver Endocannabinoid Tone and Improves Late Glycemic Control After a High-Fat Diet Challenge in Mice

artículo científico publicado en 2016

Editorial [Hot Topic: New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels (Executive Editors: V. Di Marzo and K. Starowicz)]

scientific article published on 01 January 2008

Effect of acyclic monoterpene alcohols and their derivatives on TRP channels

artículo científico publicado en 2014

Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels

artículo científico publicado en 2014

Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood

artículo científico publicado en 2010

Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice.

artículo científico publicado en 2011

Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels

artículo científico publicado en 2003

Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis

scientific article published on 17 July 2014

Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes.

artículo científico publicado en 2007

Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels

artículo científico publicado en 2005

Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation

artículo científico publicado en 2011

Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems

artículo científico publicado en 2002

Effects of Dietary Bisphenol A on the Reproductive Function of Gilthead Sea Bream (Sparus aurata) Testes

scientific article published on 10 October 2019

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes ⬇️

artículo científico publicado en 2011

Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity

scientific article published on 15 February 2016

Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity

artículo científico publicado en 2011

Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice.

artículo científico publicado en 2014

Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice

artículo científico publicado en 2018

Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women With Endometriosis

artículo científico publicado en 2016

Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity.

artículo científico publicado en 2011

Elevation of Plasma 2-Arachidonoylglycerol Levels in Alzheimer's Disease Patients as a Potential Protective Mechanism against Neurodegenerative Decline

artículo científico publicado en 2015

Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid typ

artículo científico publicado en 2005

Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists

artículo científico publicado en 2018

Enantioselective synthesis and vanilloid activity evaluation of 1-beta-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks

artículo científico publicado en 2007

Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9α epimer, 1-(R)-hydroxyisotadeonal

Enantioselective synthesis of 3(S)-hydroxy polygodial derivatives and evaluation of their vanilloid activity

Enantiospecific synthesis of bioactive hydroxyeicosatetraenoic acids (HETEs) in Hydra magnipapillata

artículo científico publicado en 1994

Endocannabinoid chemical biology: a tool for the development of novel therapies

artículo científico publicado en 2009

Endocannabinoid control of food intake and energy balance

artículo científico publicado en 2005

Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet

artículo científico publicado en 2008

Endocannabinoid modulation in the olfactory epithelium

scientific article published on January 2010

Endocannabinoid overactivity and intestinal inflammation

artículo científico publicado en 2006

Endocannabinoid pathways and their role in multiple sclerosis-related muscular dysfunction ⬇️

artículo científico publicado el 1 de abril de 2011

Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation

artículo científico

Endocannabinoid signaling at the periphery: 50 years after THC.

artículo científico publicado en 2015

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning

artículo científico publicado en 2008

Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight ⬇️

artículo científico publicado el 1 de enero de 2011

Endocannabinoid signalling and the deteriorating brain

artículo científico publicado en 2015

Endocannabinoid system and mood disorders: priming a target for new therapies

artículo científico publicado en 2012

Endocannabinoid-dependent disinhibition of orexinergic neurons: Electrophysiological evidence in leptin-knockout obese mice

artículo científico publicado en 2017

Endocannabinoids

artículo científico publicado en 1998

Endocannabinoids Part II: pathological CNS conditions involving the endocannabinoid system and their possible treatment with endocannabinoid-based drugs

artículo científico publicado en 2001

Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications

artículo científico publicado en 2005

Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels

artículo científico publicado en 2006

Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders

artículo científico publicado en 2016

Endocannabinoids and energy homeostasis: an update

artículo científico publicado en 2014

Endocannabinoids and neuropathic pain: focus on neuron-glia and endocannabinoid-neurotrophin interactions

artículo científico

Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology

artículo científico publicado en 2007

Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick

artículo científico publicado en 2003

Endocannabinoids and the control of energy balance

artículo científico publicado en 2006

Endocannabinoids and the regulation of their levels in health and disease

artículo científico publicado en 2007

Endocannabinoids as physiological regulators of colonic propulsion in mice

artículo científico publicado en 2002

Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs

artículo científico publicado en 2010

Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase

artículo científico publicado en 2011

Endocannabinoids in Energy Homeostasis and Metabolic Disorders

Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats.

artículo científico publicado en 2012

Endocannabinoids in nervous system health and disease: the big picture in a nutshell

artículo científico publicado en 2012

Endocannabinoids in the new millennium

artículo científico publicado en 2002

Endocannabinoids link feeding state and auditory perception-related gene expression.

artículo científico publicado en 2004

Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats.

artículo científico publicado en 2009

Endocannabinoids: An appetite for fat ⬇️

artículo científico publicado el 21 de julio de 2011

Endocannabinoids: a unique opportunity to develop multitarget analgesics

artículo científico publicado en 2013

Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action

artículo científico publicado en 1998

Endocannabinoids: some like it fat (and sweet too).

artículo científico publicado en 2008

Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake.

artículo científico publicado en 2006

Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy

artículo científico publicado en 2016

Endovanilloid signaling in pain

artículo científico publicado en 2002

Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels

artículo científico publicado en 2004

Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems.

artículo científico publicado en 2010

Enhancement of Anandamide Formation in the Limbic Forebrain and Reduction of Endocannabinoid Contents in the Striatum of Δ9-Tetrahydrocannabinol-Tolerant Rats

artículo científico publicado en 2000

Erratum to: Cannabinoids in the Treatment of Neurological Disorders

artículo científico publicado en 2015

Erratum to: Responses of peripheral endocannabinoids and endocannabinoid‑related compounds to hedonic eating in obesity

article

Evaluation of the endogenous cannabinoid system in mediating the behavioral effects of dipyrone (metamizol) in mice ⬇️

artículo científico publicado el 1 de octubre de 2012

Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis

artículo científico publicado en 2001

Evolutionary origins of the endocannabinoid system

article

Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter

artículo científico publicado en 2010

Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS.

artículo científico publicado en 2015

FAAH and anandamide: is 2-AG really the odd one out?

artículo científico publicado en 2008

FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug

artículo científico publicado en 2018

Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents

artículo científico publicado en 2016

Fatty acid amide hydrolase controls mouse intestinal motility in vivo

artículo científico publicado en 2005

Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications

artículo científico publicado en 2002

Fetal cannabinoid receptors and the "dis-joint-ed" brain

artículo científico publicado en 2014

Fifty years of ‘cannabinoid research’ and the need for a new nomenclature

Finding of endocannabinoids in human eye tissues: implications for glaucoma

artículo científico publicado en 2005

Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response

artículo científico publicado en 1999

First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands

artículo científico publicado en 2005

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest

Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation

artículo científico publicado en 2006

Foreword

From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology

artículo científico publicado en 2016

From endocannabinoid profiling to 'endocannabinoid therapeutics'.

artículo científico publicado en 2009

Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism

artículo científico publicado en 2013

Functional interaction between TRPV1 and mu-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia

artículo científico publicado en 2009

Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin

artículo científico publicado en 2008

Further evidence for the existence of a specific process for the membrane transport of anandamide

artículo científico publicado en 2004

Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system

artículo científico publicado en 2008

Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy

artículo científico publicado en 2018

Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB₁R signaling and anxiety-like behavior.

artículo científico publicado en 2015

Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta

artículo científico publicado en 2013

Gut feelings about the endocannabinoid system ⬇️

artículo científico publicado el 1 de mayo de 2011

Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists

artículo científico publicado en 2003

Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: definition of the structural determinants for enzyme inhibition

scholarly article in RSC Advances, vol. 6 no. 69, 2016

Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study

artículo científico publicado en 2012

Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism

scientific article published on 18 May 2020

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

artículo científico publicado en 2015

Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors

artículo científico publicado en 2003

Homology modeling in tandem with 3D-QSAR analyses: A computational approach to depict the agonist binding site of the human CB2 receptor

artículo científico publicado en 2011

Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

artículo científico publicado en 2015

Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.

artículo científico publicado en 2001

Identification and functional characterization of brainstem cannabinoid CB2 receptors

artículo científico publicado en 2005

Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.

artículo científico publicado en 2001

Identification of endocannabinoids and related compounds in human fat cells

artículo científico publicado en 2007

Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain

artículo científico publicado en 2007

Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain

artículo científico publicado en 2006

Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system.

artículo científico publicado en 2013

Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines

artículo científico publicado en 2013

In Silico Identification and Experimental Validation of (-)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator

artículo científico publicado en 2019

In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB(2) receptor inverse agonists

artículo científico publicado en 2009

In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.

artículo científico publicado en 2006

In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake

artículo científico publicado en 2004

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon

artículo científico publicado en 2007

Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis

artículo científico publicado en 2014

Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice

artículo científico publicado en 2006

Indole-2-carboxamides as allosteric modulators of the cannabinoid CB₁ receptor.

artículo científico publicado en 2012

Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation.

artículo científico publicado en 2015

Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB(1) receptors: a keratinocyte-dependent effect

artículo científico publicado en 2011

Inhibitors of endocannabinoid breakdown for pain: Not so FA(AH)cile, after all ⬇️

artículo científico publicado el 10 de julio de 2012

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice

artículo científico publicado en 2012

Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel.

artículo científico publicado en 2015

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.

artículo científico publicado en 2008

Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice

artículo científico publicado en 2008

Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression

artículo científico publicado en 2011

Interactions between synthetic vanilloids and the endogenous cannabinoid system

artículo científico publicado en 1998

Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP).

artículo científico publicado en 1986

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueou

artículo científico publicado en 2016

Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo

artículo científico publicado en 2008

Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands

artículo científico publicado en 2010

Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice

artículo científico publicado en 2011

Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors

artículo científico publicado en 2012

Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells

artículo científico publicado en 1999

Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinical data, and first human studies

artículo científico publicado en 2005

Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia

artículo científico publicado en 2008

Iodinated N-acylvanillamines: potential "multiple-target" anti-inflammatory agents acting via the inhibition of t-cell activation and antagonism at vanilloid TRPV1 channels.

artículo científico publicado en 2006

Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels

artículo científico publicado en 2014

Kavalactones and the endocannabinoid system: the plant-derived yangonin is a novel CB₁ receptor ligand

artículo científico publicado en 2012

Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects

artículo científico publicado en 2011

Leptin-regulated endocannabinoids are involved in maintaining food intake

artículo científico publicado en 2001

Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels

artículo científico publicado en 2012

Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome

artículo científico publicado en 2019

Lipidomic methodologies applicable to the study of endocannabinoids and related compounds: Endocannabinoidomics

Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels

artículo científico publicado en 2005

Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes

artículo científico publicado en 2001

Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase

artículo científico publicado en 2004

Manipulation of the endocannabinoid system by a general anaesthetic

artículo científico publicado en 2003

Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring

artículo científico publicado en 2010

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells

artículo científico publicado en 2007

Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats

artículo científico publicado en 2011

Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs

artículo científico publicado en 2007

Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects

artículo científico publicado en 2012

Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds

artículo científico publicado en 2012

Mooreamide A: a cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii

artículo científico publicado en 2014

N-Acyldopamines and N-Acylserotonins: From Synthetic Pharmacological Tools to Endogenous Multitarget Mediators

scholarly article published 2015

N-Acylvanillamides: development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor

artículo científico publicado en 2002

N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.

artículo científico publicado en 2018

N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors

artículo científico publicado en 2007

N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia

artículo científico publicado en 2003

N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities

artículo científico publicado en 2010

N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity

artículo científico publicado en 2011

Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligands

Native opioid-like peptides in Squilla mantis ganglia

artículo científico publicado en 1985

Negative Regulation of Leptin-induced Reactive Oxygen Species (ROS) Formation by Cannabinoid CB1 Receptor Activation in Hypothalamic Neurons.

artículo científico publicado en 2015

Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P

artículo científico publicado en 2006

Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

artículo científico publicado en 2012

Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide

scientific article published on 01 October 2000

Neuronal and glial alterations in the cerebellar cortex of maternally deprived rats: gender differences and modulatory effects of two inhibitors of endocannabinoid inactivation

artículo científico publicado en 2008

Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system

artículo científico publicado en 2006

Neuropeptides and inflammatory mediators: bidirectional regulatory mechanisms

artículo científico publicado en 1989

Neuropeptides and leukotriene biosynthesis: The effect of calcitonin, peptide histidine valine-42, helodermin, neuropeptide Y and galanin

artículo científico publicado en 1988

Neuropeptides and leukotriene release: effect of peptide histidine isoleucine and secretin in platelet activating factor-stimulated rat lung

artículo científico publicado en 1987

New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists

artículo científico publicado en 2007

New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain

artículo científico publicado en 2007

New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide

artículo científico publicado en 2008

New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies

artículo científico publicado en 2005

New perspectives on enigmatic vanilloid receptors.

artículo científico publicado en 2000

New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis

artículo científico publicado en 2006

New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity

artículo científico publicado en 2015

New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo

artículo científico publicado en 2009

New tetrazole-based selective anandamide uptake inhibitors

artículo científico publicado en 2008

Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues

artículo científico publicado en 2002

Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels

artículo científico publicado en 2009

Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms

artículo científico publicado en 2013

Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action

artículo científico publicado en 2011

Non-psychotropic analgesic drugs from the endocannabinoid system: “Magic bullet” or “multiple-target” strategies? ⬇️

artículo científico publicado el 13 de marzo de 2013

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

artículo científico publicado en 2009

Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability

artículo científico publicado en 2014

Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level.

artículo científico publicado en 2001

Novel Inhibitors of Brain, Neuronal, and Basophilic Anandamide Amidohydrolase

artículo científico publicado en 1997

Novel bioactive metabolites of dipyrone (metamizol)

artículo científico publicado en 2012

Novel mechanisms in obesity, type 2 diabetes and accompanying inflammation: focus on lipid signaling

scholarly article by Vincenzo Di Marzo published December 2010 in Drug discovery today. Disease mechanisms

Novel selective and metabolically stable inhibitors of anandamide cellular uptake

artículo científico publicado en 2003

Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus.

artículo científico publicado en 1997

Occurrence and possible biological role of the endocannabinoid system in the sea squirt Ciona intestinalis

artículo científico publicado en 2005

Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats

scientific article published on 16 April 2019

Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence

artículo científico publicado en 2007

Orexin-A and Endocannabinoid Activation of the Descending Antinociceptive Pathway Underlies Altered Pain Perception in Leptin Signaling Deficiency

artículo científico publicado en 2015

Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling

artículo científico publicado en 2016

Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats

artículo científico publicado en 2007

Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity

artículo científico publicado en 2006

Oxytoxins, bioactive molecules produced by the marine opisthobranch mollusc Oxynoe olivacea from a diet-derived precursor

artículo científico publicado en 1990

PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines.

artículo científico publicado en 2013

Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse

artículo científico publicado en 2017

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide

artículo científico publicado en 2011

Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors

artículo científico publicado en 2001

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells

artículo científico publicado en 2001

Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB₁ receptors and TRPV1 channels

artículo científico publicado en 2014

Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis

artículo científico publicado en 2016

Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

artículo científico publicado en 2015

Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent

artículo científico publicado en 2014

Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals.

artículo científico publicado en 2005

Palmitoylethanolamide: biochemistry, pharmacology and therapeutic use of a pleiotropic anti-inflammatory lipid mediator

artículo científico publicado en 2013

Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature

artículo científico publicado en 2012

Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception

artículo científico publicado en 2007

Peripheral Endocannabinoid Responses to Hedonic Eating in Binge-Eating Disorder

artículo científico publicado en 2017

Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle

scientific article published on September 2011

Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding

artículo científico publicado en 2009

Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia

scientific article published on 26 November 2018

Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus

artículo científico publicado en 2007

Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis

artículo científico publicado en 2017

Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis.

artículo científico publicado en 2005

Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin

artículo científico publicado en 1999

Phytocannabinoids beyond the Cannabis plant - do they exist?

artículo científico publicado en 2010

Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics

artículo científico publicado en 2013

Placebo effects in a multiple sclerosis spasticity enriched clinical trial with the oromucosal cannabinoid spray (THC/CBD): dimension and possible causes

artículo científico publicado en 2014

Plant, synthetic, and endogenous cannabinoids in medicine

artículo científico publicado en 2006

Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.

artículo científico publicado en 2008

Platelet activating factor-mediated leukotriene biosynthesis in rat lungs: effect of prostaglandins E1 and F1a

artículo científico publicado en 1987

Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism

artículo científico publicado en 2013

Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?

artículo científico publicado en 2008

Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: development, characterization and in vitro evaluation of their antitumoral efficacy

artículo científico publicado en 2012

Polymorphism rs1761667 in the CD36 Gene Is Associated to Changes in Fatty Acid Metabolism and Circulating Endocannabinoid Levels Distinctively in Normal Weight and Obese Subjects

artículo científico publicado en 2017

Polypharmacology Shakes Hands with Complex Aetiopathology

artículo científico publicado en 2015

Possible Anandamide and Palmitoylethanolamide involvement in human stroke

artículo científico publicado en 2010

Possible endocannabinoid control of colorectal cancer growth

artículo científico publicado en 2003

Possible involvement of endocannabinoids in the increase of morphine consumption in maternally deprived rat.

artículo científico publicado en 2012

Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells

artículo científico publicado en 1996

Preface

artículo científico publicado en 2015

Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons.

artículo científico publicado en 2004

Preparation and characterization of Δ(9)-tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines

artículo científico publicado en 2013

Presence and regulation of the endocannabinoid system in human dendritic cells

artículo científico publicado en 2002

Prostaglandin F-1,15-lactone fatty acyl esters: a prostaglandin lactone pathway branch developed during the reproduction and early larval stages of a marine mollusc

artículo científico publicado en 1992

Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism

artículo científico publicado en 2004

Prostamide F(2) α receptor antagonism combined with inhibition of FAAH may block the pro-inflammatory mediators formed following selective FAAH inhibition

artículo científico publicado en 2014

Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury

artículo científico publicado en 2020

Protective activation of the endocannabinoid system during ischemia in dopamine neurons

artículo científico publicado en 2006

Protective effect of palmitoylethanolamide in a rat model of cystitis

artículo científico publicado en 2014

Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy

artículo científico publicado en 2011

Protective role of palmitoylethanolamide in contact allergic dermatitis

artículo científico publicado en 2009

Questions & Answers

artículo científico publicado en 2011

RIA/chromatographic evidence for novel opioid peptide(s) in Squilla mantis ganglia

artículo científico publicado en 1986

Rapid Combinatorial Access to a Library of 1,5-Disubstituted-3-indole-N-alkylacetamides as CB2 Receptor Ligands

artículo científico publicado en 2009

Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

artículo científico publicado en 2012

Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists

artículo científico publicado en 2009

Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis

artículo científico publicado en 2009

Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins

artículo científico publicado en 2007

Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids

artículo científico publicado en 2007

Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia

artículo científico publicado en 2006

Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor

artículo científico publicado en 2011

Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity

article

Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy

artículo científico publicado en 2018

Rimonabant in rats with a metabolic syndrome: good news after the depression.

artículo científico publicado en 2008

Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala

artículo científico publicado en 2013

Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex

artículo científico publicado en 2007

Role of 2-Arachidonoyl-Glycerol and CB1 Receptors in Orexin-A-Mediated Prevention of Oxygen-Glucose Deprivation-Induced Neuronal Injury

artículo científico publicado en 2020

Role of N-Arachidonoyl-Serotonin (AA-5-HT) in Sleep-Wake Cycle Architecture, Sleep Homeostasis, and Neurotransmitters Regulation

artículo científico publicado en 2017

Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation

artículo científico publicado en 2013

Role of endocannabinoids and endovanilloids in Ca2+ signalling

artículo científico publicado en 2009

Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.

artículo científico publicado en 2009

Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons.

artículo científico publicado en 2015

Role of the endocannabinoid system in the control of mouse myometrium contractility during the menstrual cycle

artículo científico publicado en 2016

Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat.

artículo científico publicado en 2000

Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders ⬇️

artículo científico publicado el 11 de julio de 2012

Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle

artículo científico publicado en 2004

Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena

artículo científico publicado en 2003

Sesquiterpenoids from Common Ragweed (Ambrosia artemisiifolia L.), an Invasive Biological Polluter

Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders

artículo científico publicado en 2007

Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice

artículo científico publicado en 2016

Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida

artículo científico publicado en 2013

Spinal anandamide produces analgesia in neuropathic rats: Possible CB1- and TRPV1-mediated mechanisms

artículo científico publicado en 2011

Structure-Based Virtual Screening: Identification of Novel CB2 Receptor Ligands

Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties

scientific article published on 02 July 2019

Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist

artículo científico publicado en 2014

Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide

artículo científico publicado en 2008

Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease

artículo científico publicado en 2007

Synthesis and Biological Evaluation of Phorbol-Resiniferatoxin (RTX) Hybrids

Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes

artículo científico publicado en 2012

Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators

artículo científico publicado en 2011

Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands

artículo científico publicado en 2010

Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands

artículo científico publicado en 2009

Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol

artículo científico publicado en 2009

Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease

artículo científico publicado en 2018

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

artículo científico publicado en 2016

Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands ⬇️

artículo científico publicado el 27 de octubre de 2010

Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands

scientific article published on 02 December 2014

Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides

artículo científico publicado en 2008

Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics

artículo científico publicado en 2006

TRPA1 channels as targets for resveratrol and related stilbenoids

artículo científico publicado en 2015

TRPV1 channels control synaptic plasticity in the developing superior colliculus.

artículo científico publicado en 2009

TRPV1 in Neuropathic Pain and Neurological and Neuropsychiatric Disorders

TRPV1 modulators: Synthesis and in vitro evaluation of 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives

artículo científico publicado en 2015

TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications

artículo científico publicado en 2008

TRPV1-dependent and -independent alterations in the limbic cortex of neuropathic mice: impact on glial caspases and pain perception

artículo científico publicado en 2011

Targeted lipidomics: endocannabinoids and other endolipid modulators

Targeting the endocannabinoid system in cancer therapy: a call for further research

artículo científico publicado en 2002

Targeting the endocannabinoid system: to enhance or reduce?

artículo científico publicado en 2008

Taste sensitivity to 6-n-propylthiouracil is associated with endocannabinoid plasma levels in normal-weight individuals.

artículo científico publicado en 2013

Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism

artículo científico publicado en 2008

The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system

artículo científico publicado en 2011

The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids

artículo científico publicado en 2007

The A1 adenosine receptor as a new player in microglia physiology.

artículo científico publicado en 2014

The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus

artículo científico publicado en 2008

The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway

artículo científico publicado en 2003

The Endocannabinoid System and its Modulation by Phytocannabinoids

artículo científico

The First Dual ChE/FAAH Inhibitors: New Perspectives for Alzheimer's Disease?

artículo científico publicado en 2012

The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.

artículo científico publicado en 2011

The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism

artículo científico publicado en 2001

The administration of endocannabinoid uptake inhibitors OMDM-2 or VDM-11 promotes sleep and decreases extracellular levels of dopamine in rats

artículo científico publicado en 2012

The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats

artículo científico publicado en 2008

The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain.

artículo científico publicado en 2008

The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region

artículo científico publicado en 2004

The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels

artículo científico publicado en 2015

The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine

scientific article published on 30 June 2009

The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats

artículo científico publicado en 2011

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling

artículo científico publicado en 2007

The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

artículo científico publicado en 2013

The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties

artículo científico publicado en 2013

The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis

artículo científico publicado en 2014

The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice

artículo científico publicado en 2010

The effect of a cAMP analogue on Ca2+ ionophore-, antigen- and agonist-induced inositol phosphate release in rat basophilic leukaemia (RBL-1) cells

artículo científico publicado en 1992

The effect of cannabichromene on adult neural stem/progenitor cells

artículo científico publicado en 2013

The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels

artículo científico publicado en 2014

The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis.

artículo científico publicado en 2010

The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneurons

artículo científico publicado en 2008

The endocannabinoid and endovanilloid systems and their interactions in neuropathic pain

The endocannabinoid signalling system: biochemical aspects

artículo científico publicado en 2005

The endocannabinoid system and its therapeutic exploitation

artículo científico publicado en 2004

The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis

scholarly article

The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation

scientific article published on June 2009

The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders

artículo científico publicado en 2013

The endocannabinoid system in metabolic control: a preface

artículo científico publicado en 2009

The endocannabinoid system in obesity and type 2 diabetes.

artículo científico publicado en 2008

The endocannabinoid system in renal cells: regulation of Na(+) transport by CB1 receptors through distinct cell signalling pathways.

artículo científico publicado en 2014

The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders

artículo científico publicado en 2003

The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake

artículo científico publicado en 2005

The endocannabinoid system is modulated in response to spinal cord injury in rats

artículo científico publicado en 2008

The endocannabinoid system mediates aerobic exercise-induced antinociception in rats.

artículo científico publicado en 2013

The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity. Mechanism and regulation

artículo científico publicado en 2002

The endocannabinoid system--back to the scene of cardiometabolic risk factors control?

artículo científico publicado en 2014

The endocannabinoid system: a general view and latest additions

artículo científico publicado en 2004

The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation

scientific article published on 04 March 2009

The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation.

artículo científico publicado en 1998

The endogenous cannabinoid system controls extinction of aversive memories

artículo científico publicado en 2002

The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption.

artículo científico publicado en 2008

The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy.

artículo científico publicado en 2011

The ever-expanding world of the endocannabinoids: A concise introduction

The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats

artículo científico publicado en 2002

The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG.

scientific article published on 17 October 2013

The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma

artículo científico publicado en 2010

The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain

artículo científico publicado en 2016

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

artículo científico publicado en 2010

The role of cyclic AMP in the inhibition of leukotriene biosynthesis by neuropeptides

artículo científico publicado en 1989

The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet

artículo científico publicado en 2008

The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization

artículo científico publicado en 2007

The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses

artículo científico publicado en 2008

The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity

artículo científico

The sleep inducing factor oleamide is produced by mouse neuroblastoma cells

artículo científico publicado en 1997

The synthesis, release and action of leukotrienes in the isolated, unstimulated, buffer-perfused rat heart

artículo científico publicado en 1989

The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination

artículo científico publicado en 2005

The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase

artículo científico publicado en 2001

Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy

article by Carlamaria Zoja et al published 9 December 2015 in Nephron

Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2.

artículo científico publicado en 2010

Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis.

artículo científico publicado en 2015

Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’

artículo científico publicado en 1995

Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway

scientific article published on 25 September 2018

Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors

artículo científico publicado en 1999

Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation

artículo científico publicado en 2006

Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility

artículo científico publicado en 2004

Why do cannabinoid receptors have more than one endogenous ligand? ⬇️

artículo científico publicado el 5 de diciembre de 2012

Why endocannabinoids are not all alike

artículo científico publicado en 2008

beta-Endorphin in neuroblastoma x glioma hybrid cells

artículo científico publicado en 1985

α-and γ-Pyrone-poly·propionates from the mediterranean ascoglossan mollusc ercolania funerea

article published in 1992

“De-liver-ance” From CB1: A Way to Counteract Insulin Resistance? ⬇️

artículo científico publicado el 27 de marzo de 2012

Lista de obras de Vincenzo Di Marzo

"Redundancy" of endocannabinoid inactivation: new challenges and opportunities for pain control

'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.

1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor

1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB1 or CB2 receptor ligands

2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons.

2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators

<i>Mgll</i> Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota

A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists

A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up

A marine mollusc provides the first example of in vivo storage of prostaglandins: Prostaglandin-1,15-lactones

A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis

A new strategy to block tumor growth by inhibiting endocannabinoid inactivation

A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects

A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons

A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease

A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats

A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase

A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid

Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels

Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol

Acute neuronal injury, excitotoxicity, and the endocannabinoid system

Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats

Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis

Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Alteration of the endocannabinoid system in mouse brain during prion disease

Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis

Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance

Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain

Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems.

An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?

An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice

An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors

An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

An introduction to the endocannabinoid system: from the early to the latest concepts

Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors

Analogues of perillaketone as highly potent agonists of TRPA1 channel.

Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines

Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period

Analysis of the “endocannabinoidome” in peripheral tissues of obese Zucker rats

Anandamide Uptake by Human Endothelial Cells and Its Regulation by Nitric Oxide

Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish

Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator

Anandamide and other cannabimimetic fatty acid derivatives-foreword

Anandamide as an intracellular messenger regulating ion channel activity

Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration.

Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB.

Anandamide inhibits adhesion and migration of breast cancer cells

Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.

Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release

Anandamide produced by Ca(2+)-insensitive enzymes induces excitation in primary sensory neurons

Anandamide receptors

Anandamide – the other side of the coin

Anandamide, an endogenous cannabinomimetic eicosanoid: ‘Killing two birds with one stone’ ⬇️

Anandamide-derived prostamide F2α negatively regulates adipogenesis

Anandamide-loaded nanoparticles: Preparation and characterization

Anti-inflammatory effect of palmitoylethanolamide on human adipocytes

Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults

Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy

Antithrombin Chicago, amino acid substitution of arginine 393 to histidine

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells

Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels.

Aquatic invertebrates open up new perspectives in eicosanoid research: biosynthesis and bioactivity

Arachidonic Acid and Eicosanoids in Hydra: Possible Endogenous Signals Involved in Chemoreception and Modulation of the Feeding Behaviour ⬇️

Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions

Arachidonic acid, protein kinase C activators and bud formation in Hydra vulgaris

Arachidonoylserotonin and Other Novel Inhibitors of Fatty Acid Amide Hydrolase ⬇️

Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis

Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease

Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret

Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors