Lista de obras - George L. Drusano - Dominio Público Uruguay

Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

artículo científico publicado en 2014

Anidulafungin pharmacokinetics and microbial response in neutropenic mice with disseminated candidiasis

artículo científico publicado en 2006

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

scientific article published in 2007

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

artículo científico publicado en 2004

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

artículo científico publicado en 2003

Application of antimicrobial pharmacodynamic concepts into clinical practice: focus on beta-lactam antibiotics: insights from the Society of Infectious Diseases Pharmacists

artículo científico publicado en 2006

Are vancomycin trough concentrations adequate for optimal dosing?

artículo científico publicado en 2013

Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa

artículo científico publicado en 2005

Chikungunya Virus: In Vitro Response to Combination Therapy with Ribavirin and Interferon-α2a

artículo científico publicado en 2016

Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.

artículo científico publicado en 2006

Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype

artículo científico publicado en 2022

Combination treatment with meropenem plus levofloxacin is synergistic against Pseudomonas aeruginosa infection in a murine model of pneumonia

artículo científico publicado en 2014

Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

artículo científico publicado en 2019

Comparative Efficacies of Candidate Antibiotics against Yersinia pestis in an In Vitro Pharmacodynamic Model ⬇️

artículo científico publicado el 12 de abril de 2011

Comparative pharmacokinetic analysis by standard two-stage method versus nonparametric population modeling

artículo científico publicado en 2003

Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague

artículo científico publicado en 2007

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

artículo científico publicado en 2009

Competitive inhibition of renal tubular secretion of gemifloxacin by probenecid

artículo científico publicado en 2009

Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin

artículo científico publicado en 2007

Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective ⬇️

artículo científico publicado el 26 de marzo de 2011

Daptomycin exposure and the probability of elevations in the creatine phosphokinase level: data from a randomized trial of patients with bacteremia and endocarditis

artículo científico publicado en 2010

Derivation of an in vivo drug exposure breakpoint for flucytosine against Candida albicans and Impact of the MIC, growth rate, and resistance genotype on the antifungal effect

artículo científico publicado en 2006

Developing new drugs for the therapy of Mycobacterium tuberculosis: What information do we get from pre-clinical animal models?

scientific article published on 21 September 2020

Differential effects of linezolid and ciprofloxacin on toxin production by Bacillus anthracis in an in vitro pharmacodynamic system

artículo científico publicado en 2011

Dose Optimization of Moxifloxacin and Linezolid Against Tuberculosis Using Mathematical Modeling and Simulation

artículo científico publicado en 2018

Dose Range Evaluation of Mycograb C28Y Variant, a Human Recombinant Antibody Fragment to Heat Shock Protein 90, in Combination with Amphotericin B-Desoxycholate for Treatment of Murine Systemic Candidiasis ⬇️

artículo científico publicado el 18 de abril de 2011

Early endpoints for acute bacterial skin and skin structure infections

artículo científico publicado en 2012

Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay.

artículo científico publicado en 2018

Effect of Moxifloxacin plus Pretomanid against in Log-phase, Acid-phase and Non-Replicating-Persister (NRP)-phase in an i Assay

artículo científico publicado en 2018

Effect of half-life on the pharmacodynamic index of zanamivir against influenza virus delineated by a mathematical model

artículo científico publicado en 2011

Effect of neutropenia and treatment delay on the response to antifungal agents in experimental disseminated candidiasis

artículo científico publicado en 2006

Ertapenem pharmacokinetics and pharmacodynamics during continuous ambulatory peritoneal dialysis.

artículo científico publicado en 2011

Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers.

artículo científico publicado en 2005

Evaluation of imipenem for prophylaxis and therapy of Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague

artículo científico publicado en 2014

Evaluation of once-daily vancomycin against methicillin-resistant Staphylococcus aureus in a hollow-fiber infection model

artículo científico publicado en 2011

First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae

scientific article published on 25 May 2018

First penicillin-binding protein occupancy patterns for 15 β-lactams and β-lactamase inhibitors in Mycobacterium abscessus

artículo científico publicado en 2020

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

artículo científico publicado en 2019

Frequentist and Bayesian pharmacometric-based approaches to facilitate critically needed new antibiotic development: overcoming lies, damn lies, and statistics

artículo científico publicado en 2011

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens

artículo científico publicado en 2019

Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

scientific article published on 25 April 2019

Guillain‐Barre Syndrome Associated with Immune Reconstitution ⬇️

artículo científico publicado el 14 de abril de 2003

High-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections in immunocompromised patients

artículo científico publicado en 2010

Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy

artículo científico publicado en 2007

Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model

artículo científico publicado en 2011

In memoriam: William A. Craig.

artículo científico publicado en 2015

In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae

artículo científico publicado en 2007

In vitro system for modeling influenza A virus resistance under drug pressure

artículo científico publicado en 2010

In vivo activity of oritavancin in animal infection models and rationale for a new dosing regimen in humans

artículo científico publicado en 2012

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

artículo científico publicado en 2014

Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa

artículo científico publicado en 2003

Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations

artículo científico publicado en 2007

Isoniazid’s Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion ofMycobacterium tuberculosisin the Log Phase of Growth

artículo científico publicado en 2007

L-Thyroxine vs. 3,5,3'-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

artículo científico publicado en 2009

Meropenem: laboratory and clinical data.

artículo científico publicado en 1997

Methodological features of clinical pharmacokinetic-pharmacodynamic studies of antibacterials and antifungals: a systematic review

artículo científico publicado en 2020

Natural history of Acinetobacter baumannii infection in mice

scientific article published on 18 July 2019

New EMA guideline for antimicrobial development

artículo científico publicado en 2012

Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae

articulo cientifico

Once-weekly micafungin therapy is as effective as daily therapy for disseminated candidiasis in mice with persistent neutropenia

artículo científico publicado en 2006

Optimization of the dosage of flucytosine in combination with amphotericin B for disseminated candidiasis: a pharmacodynamic rationale for reduced dosing

artículo científico publicado en 2007

Optimizing antimicrobial pharmacodynamics: dosage strategies for meropenem

artículo científico publicado en 2004

Oseltamivir-zanamivir combination therapy suppresses drug-resistant H1N1 influenza A viruses in the hollow fiber infection model (HFIM) system

artículo científico publicado en 2017

Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal therapy

artículo científico publicado en 2006

Penetration of moxifloxacin into bone evaluated by Monte Carlo simulation

artículo científico publicado en 2009

Penetration of vancomycin into epithelial lining fluid in healthy volunteers

artículo científico publicado en 2011

Pharmacodynamic analysis of a serine protease inhibitor, MK-4519, against hepatitis C virus using a novel in vitro pharmacodynamic system

artículo científico publicado en 2011

Pharmacodynamic evidence that ciprofloxacin failure against tuberculosis is not due to poor microbial kill but to rapid emergence of resistance

artículo científico publicado en 2005

Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system

artículo científico publicado en 2011

Pharmacodynamic profiling of cefepime in plasma and cerebrospinal fluid of hospitalized patients with external ventriculostomies

artículo científico publicado en 2006

Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation

artículo científico publicado en 2004

Pharmacodynamics and clinical use of anti-HIV drugs

artículo científico publicado en 2003

Pharmacodynamics for antifungal drug development: an approach for acceleration, risk minimization and demonstration of causality.

artículo científico publicado en 2016

Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum Beta Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia caused by ESBL-Producing Klebsiella pneumoniae

scientific article published on 06 April 2020

Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens

artículo científico publicado en 2005

Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity

artículo científico publicado en 2005

Pharmacodynamics of cefepime in patients with Gram-negative infections

artículo científico publicado en 2002

Pharmacodynamics of cidofovir for vaccinia virus infection in an in vitro hollow-fiber infection model system

artículo científico publicado en 2008

Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model

artículo científico publicado en 2006

Pharmacokinetic-pharmacodynamic analysis for efficacy of ceftaroline fosamil in patients with acute bacterial skin and skin structure infections

artículo científico publicado en 2014

Pharmacokinetics and pharmacodynamics of cefepime in patients with various degrees of renal function

artículo científico publicado en 2003

Pharmacokinetics and pharmacodynamics of fluoroquinolones

scientific article published on 01 April 1998

Pharmacokinetics and pharmacodynamics of intravenous daptomycin during continuous ambulatory peritoneal dialysis.

artículo científico publicado en 2011

Pharmacokinetics of tedizolid, sutezolid, and sutezolid-M1 in non-human primates

artículo científico publicado en 2020

Pharmacokinetics-pharmacodynamics of quinolones against Streptococcus pneumoniae in patients with community-acquired pneumonia

scientific article published on 25 June 2008

Phenotypic drug susceptibility assay for influenza virus neuraminidase inhibitors

artículo científico publicado en 2004

Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy

artículo científico publicado en 2007

Population pharmacokinetic modeling and Monte Carlo simulation of varying doses of intravenous metronidazole

artículo científico publicado en 2006

Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial

artículo científico publicado en 2007

Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin

artículo científico publicado en 2007

Population pharmacokinetics of micafungin in adult patients

artículo científico publicado en 2007

Population pharmacokinetics of micafungin in pediatric patients and implications for antifungal dosing

artículo científico publicado en 2007

Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile

artículo científico publicado en 2012

Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

artículo científico publicado en 2015

Predicting efficacy of antiinfectives with pharmacodynamics and Monte Carlo simulation ⬇️

artículo científico publicado el 1 de noviembre de 2003

Prediction of the pharmacodynamically linked variable of oseltamivir carboxylate for influenza A virus using an in vitro hollow-fiber infection model system

artículo científico publicado en 2009

Probability of target attainment for ceftobiprole as derived from a population pharmacokinetic analysis of 150 subjects

artículo científico publicado en 2007

Quinolone efflux pumps play a central role in emergence of fluoroquinolone resistance in Streptococcus pneumoniae

artículo científico publicado en 2006

Refining vancomycin protein binding estimates: identification of clinical factors that influence protein binding.

artículo científico publicado en 2011

Relationship between initial vancomycin concentration-time profile and nephrotoxicity among hospitalized patients

artículo científico publicado en 2009

Reply to Wallis et al. and Mitchison et al

artículo científico publicado en 2007

Selection of a moxifloxacin dose that suppresses drug resistance in Mycobacterium tuberculosis, by use of an in vitro pharmacodynamic infection model and mathematical modeling

artículo científico publicado en 2004

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs

artículo científico publicado en 2002

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

artículo científico publicado en 2005

Surface response modeling to examine the combination of amphotericin B deoxycholate and 5-fluorocytosine for treatment of invasive candidiasis

artículo científico publicado en 2005

Telavancin penetration into human epithelial lining fluid determined by population pharmacokinetic modeling and Monte Carlo simulation

artículo científico publicado en 2008

The Funnel: A screening technique for identifying optimal two-drug combination chemotherapy regimens

artículo científico publicado en 2020

The pharmacokinetics and pharmacodynamics of micafungin in experimental hematogenous Candida meningoencephalitis: implications for echinocandin therapy in neonates

artículo científico publicado en 2008

The relationship between quinolone exposures and resistance amplification is characterized by an inverted U: a new paradigm for optimizing pharmacodynamics to counterselect resistance

artículo científico publicado en 2006

Use of pharmacokinetic and pharmacodynamic principles to determine optimal administration of daptomycin in patients receiving standardized thrice-weekly hemodialysis.

artículo científico publicado en 2011

Use of population pharmacokinetic modeling and Monte Carlo simulation to describe the pharmacodynamic profile of cefditoren in plasma and epithelial lining fluid

artículo científico publicado en 2007

Vancomycin exposure in patients with methicillin-resistant Staphylococcus aureus bloodstream infections: how much is enough?

artículo científico publicado en 2014

Zanamivir, at 600 Milligrams Twice Daily, Inhibits Oseltamivir-Resistant 2009 Pandemic H1N1 Influenza Virus in an In Vitro Hollow-Fiber Infection Model System ⬇️

artículo científico publicado el 24 de enero de 2011

Lista de obras de George L. Drusano

Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

Anidulafungin pharmacokinetics and microbial response in neutropenic mice with disseminated candidiasis

Antimicrobial Resistance: Pharmacokinetics‐Pharmacodynamics of Antimicrobial Therapy: It’s Not Just for Mice Anymore

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'.

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

Application of antimicrobial pharmacodynamic concepts into clinical practice: focus on beta-lactam antibiotics: insights from the Society of Infectious Diseases Pharmacists

Are vancomycin trough concentrations adequate for optimal dosing?

Bacterial-population responses to drug-selective pressure: examination of garenoxacin's effect on Pseudomonas aeruginosa

Chikungunya Virus: In Vitro Response to Combination Therapy with Ribavirin and Interferon-α2a

Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.

Combination Therapy to Kill Mycobacterium tuberculosis in Its Nonreplicating Persister Phenotype

Combination treatment with meropenem plus levofloxacin is synergistic against Pseudomonas aeruginosa infection in a murine model of pneumonia

Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

Comparative Efficacies of Candidate Antibiotics against Yersinia pestis in an In Vitro Pharmacodynamic Model ⬇️

Comparative pharmacokinetic analysis by standard two-stage method versus nonparametric population modeling

Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

Competitive inhibition of renal tubular secretion of gemifloxacin by probenecid

Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin

Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective ⬇️

Daptomycin exposure and the probability of elevations in the creatine phosphokinase level: data from a randomized trial of patients with bacteremia and endocarditis

Derivation of an in vivo drug exposure breakpoint for flucytosine against Candida albicans and Impact of the MIC, growth rate, and resistance genotype on the antifungal effect

Developing new drugs for the therapy of Mycobacterium tuberculosis: What information do we get from pre-clinical animal models?

Differential effects of linezolid and ciprofloxacin on toxin production by Bacillus anthracis in an in vitro pharmacodynamic system

Dose Optimization of Moxifloxacin and Linezolid Against Tuberculosis Using Mathematical Modeling and Simulation

Dose Range Evaluation of Mycograb C28Y Variant, a Human Recombinant Antibody Fragment to Heat Shock Protein 90, in Combination with Amphotericin B-Desoxycholate for Treatment of Murine Systemic Candidiasis ⬇️

Early endpoints for acute bacterial skin and skin structure infections

Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay.

Effect of Moxifloxacin plus Pretomanid against in Log-phase, Acid-phase and Non-Replicating-Persister (NRP)-phase in an i Assay

Effect of half-life on the pharmacodynamic index of zanamivir against influenza virus delineated by a mathematical model

Effect of neutropenia and treatment delay on the response to antifungal agents in experimental disseminated candidiasis

Ertapenem pharmacokinetics and pharmacodynamics during continuous ambulatory peritoneal dialysis.

Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers.

Evaluation of imipenem for prophylaxis and therapy of Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague

Evaluation of once-daily vancomycin against methicillin-resistant Staphylococcus aureus in a hollow-fiber infection model

First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae

First penicillin-binding protein occupancy patterns for 15 β-lactams and β-lactamase inhibitors in Mycobacterium abscessus

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

Frequentist and Bayesian pharmacometric-based approaches to facilitate critically needed new antibiotic development: overcoming lies, damn lies, and statistics

GC-072: A Novel Therapeutic Candidate for Oral Treatment of Melioidosis and Infections Caused by Select Biothreat Pathogens

Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Guillain‐Barre Syndrome Associated with Immune Reconstitution ⬇️

High-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections in immunocompromised patients

Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy

Impact of spores on the comparative efficacies of five antibiotics for treatment of Bacillus anthracis in an in vitro hollow fiber pharmacodynamic model

In memoriam: William A. Craig.

In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae

In vitro system for modeling influenza A virus resistance under drug pressure

In vivo activity of oritavancin in animal infection models and rationale for a new dosing regimen in humans

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa

Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations

Isoniazid’s Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion ofMycobacterium tuberculosisin the Log Phase of Growth

L-Thyroxine vs. 3,5,3'-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

Meropenem: laboratory and clinical data.

Methodological features of clinical pharmacokinetic-pharmacodynamic studies of antibacterials and antifungals: a systematic review

Natural history of Acinetobacter baumannii infection in mice

New EMA guideline for antimicrobial development

Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae

Once-weekly micafungin therapy is as effective as daily therapy for disseminated candidiasis in mice with persistent neutropenia

Optimization of the dosage of flucytosine in combination with amphotericin B for disseminated candidiasis: a pharmacodynamic rationale for reduced dosing

Optimizing antimicrobial pharmacodynamics: dosage strategies for meropenem

Oseltamivir-zanamivir combination therapy suppresses drug-resistant H1N1 influenza A viruses in the hollow fiber infection model (HFIM) system

Pathogenesis of Aspergillus fumigatus and the kinetics of galactomannan in an in vitro model of early invasive pulmonary aspergillosis: implications for antifungal therapy

Penetration of moxifloxacin into bone evaluated by Monte Carlo simulation

Penetration of vancomycin into epithelial lining fluid in healthy volunteers

Pharmacodynamic analysis of a serine protease inhibitor, MK-4519, against hepatitis C virus using a novel in vitro pharmacodynamic system

Pharmacodynamic evidence that ciprofloxacin failure against tuberculosis is not due to poor microbial kill but to rapid emergence of resistance

Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system

Pharmacodynamic profiling of cefepime in plasma and cerebrospinal fluid of hospitalized patients with external ventriculostomies

Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation

Pharmacodynamics and clinical use of anti-HIV drugs

Pharmacodynamics for antifungal drug development: an approach for acceleration, risk minimization and demonstration of causality.

Pharmacodynamics of Cefepime Combined with the Novel Extended-Spectrum Beta Lactamase (ESBL) Inhibitor Enmetazobactam for Murine Pneumonia caused by ESBL-Producing Klebsiella pneumoniae

Pharmacodynamics of an 800-mg dose of telithromycin in patients with community-acquired pneumonia caused by extracellular pathogens

Pharmacodynamics of caspofungin in a murine model of systemic candidiasis: importance of persistence of caspofungin in tissues to understanding drug activity

Pharmacodynamics of cefepime in patients with Gram-negative infections

Pharmacodynamics of cidofovir for vaccinia virus infection in an in vitro hollow-fiber infection model system

Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model