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Lista de obras de Jeffrey Weitz

'Realworld' use of non-vitamin K antagonist oral anticoagulants (NOACs): Lessons from the Dresden NOAC Registry

artículo científico publicado en 2015

2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants

artículo científico publicado en 2017

A PoTENtial Antidote: A Prohemostatic Factor Xa Variant for Reversal of Direct Oral Anticoagulants

artículo científico publicado en 2016

A Replacement for Warfarin

A Risk Assessment Tool Incorporating New Biomarkers for Cardiovascular Events in Acute Coronary Syndromes: The Organization to Assess Strategies in Ischemic Syndromes (OASIS) Risk Score

artículo científico publicado en 2016

A Test in Context: D-Dimer

artículo científico publicado en 2017

A diagnostic strategy involving a quantitative latex D-dimer assay reliably excludes deep venous thrombosis

artículo científico publicado en 2003

A dose-finding study with TAK-442, an oral factor Xa inhibitor, in patients undergoing elective total knee replacement surgery ⬇️

artículo científico publicado el 30 de septiembre de 2010

A high affinity interaction of plasminogen with fibrin is not essential for efficient activation by tissue-type plasminogen activator

artículo científico publicado en 2011

A non-anticoagulant synthetic pentasaccharide reduces inflammation in a murine model of kidney ischemia-reperfusion injury

artículo científico publicado en 2006

A novel approach to thrombin inhibition

artículo científico publicado en 2003

A randomised, double blind comparison of tecarfarin, a novel vitamin K antagonist, with warfarin. The EmbraceAC Trial.

artículo científico publicado en 2016

AB023, A Novel Antibody That Binds Factor XI and Blocks Its Activation by Factor XIIa

artículo científico publicado en 2019

Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets

artículo científico publicado en 2020

Acute coronary syndromes: a focus on thrombin

artículo científico publicado en 2002

Advances in Antithrombotic Therapy

artículo científico publicado en 2019

Advances in Therapy and the Management of Antithrombotic Drugs for Venous Thromboembolism

artículo científico publicado en 2000

Advances in Thrombosis and Hemostasis: An Introduction to the Compendium

artículo científico publicado en 2016

An omniphobic lubricant-infused coating produced by chemical vapor deposition of hydrophobic organosilanes attenuates clotting on catheter surfaces

artículo científico publicado en 2017

An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery

artículo científico publicado en 2016

An update on new anticoagulants

artículo científico publicado en 2003

Another oral thrombin inhibitor for stroke prevention in atrial fibrillation?

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers

scientific article published on 17 March 2019

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers. Reply

scientific article published on 01 August 2019

Anticoagulant-Associated Intracranial Hemorrhage in the Era of Reversal Agents

artículo científico publicado en 2017

Anticoagulants in heart disease: current status and perspectives

artículo científico publicado en 2007

Anticoagulation for Mechanical Heart Valves: Will Oral Factor Xa Inhibitors Be Effective?

artículo científico publicado en 2017

Anticoagulation for ST-Segment Elevation Myocardial Infarction

Anticoagulation therapy in 2015: where we are and where we are going

artículo científico publicado en 2015

Anticoagulation therapy patterns for acute treatment of venous thromboembolism in GARFIELD-VTE patients

artículo científico publicado en 2019

Anticoagulation therapy. Dabigatran and risk of myocardial infarction

artículo científico publicado en 2012

Antiphospholipid Antibodies and Recurrent Thrombosis after a First Unprovoked Venous Thromboembolism.

artículo científico publicado en 2018

Antiplatelet drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

artículo científico publicado en 2012

Antiplatelet therapy in the management of atherothrombosis: recent clinical advances

scientific article published on 01 July 2018

Antithrombin-heparin covalent complex: a possible alternative to heparin for arterial thrombosis prevention

scientific article published on 01 July 2002

Antithrombin-independent anticoagulation by hypersulfated low-molecular-weight heparin

artículo científico publicado en 2002

Antithrombotic Activity of the Novel Oral Anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in Animal Models ⬇️

artículo científico publicado el 1 de noviembre de 2010

Antithrombotic Agents

scientific article published on 01 February 2019

Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

artículo científico publicado en 2004

Apixaban for extended treatment of venous thromboembolism

artículo científico publicado en 2012

Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients

artículo científico publicado en 2011

Appropriate Apixaban Dosing: Prescribers Take Note.

artículo científico publicado en 2016

Are Ticks the Answer to Medical Device-Associated Clotting?

artículo científico publicado en 2019

Arterial thrombosis is accelerated in mice deficient in histidine-rich glycoprotein

artículo científico publicado en 2015

Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events

artículo científico publicado en 2002

Assays for Measuring Rivaroxaban: Their Suitability and Limitations ⬇️

artículo científico publicado el 1 de diciembre de 2010

Assessment of Outcomes Among Patients With Venous Thromboembolism With and Without Chronic Kidney Disease

artículo científico publicado en 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in patients with non-valvular atrial fibrillation

artículo científico publicado en 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the prevention of venous thromboembolism

artículo científico publicado en 2020

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism

artículo científico publicado en 2020

Batroxobin binds fibrin with higher affinity and promotes clot expansion to a greater extent than thrombin

artículo científico publicado en 2013

Benefits and risks of extended treatment of venous thromboembolism with rivaroxaban or with aspirin

artículo científico publicado en 2018

Beyond heparin and warfarin: the new generation of anticoagulants

artículo científico publicado en 2007

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores

artículo científico publicado en 2010

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores

artículo científico publicado en 2015

Bivalent binding to gammaA/gamma'-fibrin engages both exosites of thrombin and protects it from inhibition by the antithrombin-heparin complex

artículo científico publicado en 2007

Bivalirudin, thrombin and platelets: clinical implications and future directions

artículo científico publicado en 2003

By increasing the affinity of heparin for fibrin, Zn(2+) promotes the formation of a ternary heparin-thrombin-fibrin complex that protects thrombin from inhibition by antithrombin

artículo científico publicado en 2012

COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up

scientific article published on 15 April 2020

COVID-19 coagulopathy, thrombosis, and bleeding

scientific article published on 01 July 2020

Cancer associated thrombosis in everyday practice: perspectives from GARFIELD-VTE

artículo científico publicado en 2020

Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs

artículo científico publicado en 2009

Cell-Free DNA Modulates Clot Structure and Impairs Fibrinolysis in Sepsis

artículo científico publicado en 2015

Changing paradigms in the management of venous thromboembolism

artículo científico publicado en 2006

Characteristics and Management of Patients with Venous Thromboembolism: The GARFIELD-VTE Registry

scientific article published on 28 December 2018

Characteristics and Outcomes in Patients with Venous Thromboembolism Taking Concomitant Anti-Platelet Agents and Anticoagulants in the AMPLIFY Trial

scientific article published on 16 January 2019

Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial.

artículo científico publicado en 2018

Choosing wisely: The impact of patient selection on efficacy and safety outcomes in the EINSTEIN-DVT/PE and AMPLIFY trials

artículo científico publicado en 2016

Ciraparantag for enoxaparin reversal: Adding to the evidence.

artículo científico publicado en 2016

Clinical Impact of Bleeding in Cancer-Associated Venous Thromboembolism: Results from the Hokusai VTE Cancer Study

scientific article published on 30 July 2018

Clinical implications of incidental venous thromboembolism in cancer patients

artículo científico publicado en 2020

Clinical presentation and course of bleeding events in patients with venous thromboembolism, treated with apixaban or enoxaparin and warfarin. Results from the AMPLIFY trial

artículo científico publicado en 2016

Coagulation assays

artículo científico publicado en 2005

Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease

scientific article published on 01 April 2019

Comment on model-based meta-analysis to evaluate optimal doses of direct oral factor Xa inhibitors in atrial fibrillation patients

scholarly article published 27 November 2018

Comparative effectiveness of oral anticoagulants in venous thromboembolism: GARFIELD-VTE

scientific article published on 28 April 2020

Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development

artículo científico publicado en 2009

Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism

artículo científico publicado en 2003

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

artículo científico publicado en 2013

Contribution of host-derived tissue factor to tumor neovascularization

artículo científico publicado en 2008

Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo

artículo científico publicado en 2012

Dabigatran Reversal With Idarucizumab in Patients Requiring Urgent Surgery: A Subanalysis of the RE-VERSE AD Study

artículo científico publicado en 2019

Dabigatran Reversal With Idarucizumab in Patients With Renal Impairment

artículo científico publicado en 2019

Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function

artículo científico publicado en 2016

Dabigatran attenuates thrombin generation to a lesser extent than warfarin: could this explain their differential effects on intracranial hemorrhage and myocardial infarction?

artículo científico publicado en 2013

Dabigatran etexilate for prevention of venous thromboembolism

artículo científico publicado en 2009

Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve-Induced Thrombin Generation

artículo científico publicado en 2015

Dabigatran-related coagulopathy: when can we assume the effect has "worn off"?

artículo científico publicado en 2014

Delayed but not Early Treatment with DNase Reduces Organ Damage and Improves Outcome in a Murine Model of Sepsis

artículo científico publicado en 2015

Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran

artículo científico publicado en 2015

Direct Oral Anticoagulants for Pulmonary Embolism: Importance of Anatomical Extent

scientific article published on 08 January 2018

Direct oral anticoagulants for cancer-associated venous thromboembolism: a systematic review and meta-analysis

scientific article published on 12 May 2020

Direct thrombin inhibitors

artículo científico publicado en 2002

Direct thrombin inhibitors in acute coronary syndromes: present and future

artículo científico publicado en 2002

Direct thrombin inhibitors in cardiac disease

artículo científico publicado en 2003

Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism. An analysis of the randomised, double-blind HOKUSAI VTE trial

artículo científico publicado en 2016

Dual surface modification with PEG and corn trypsin inhibitor: effect of PEG:CTI ratio on protein resistance and anticoagulant properties

scientific article published on 12 January 2012

Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease

artículo científico publicado en 2020

Early time courses of recurrent thromboembolism and bleeding during apixaban or enoxaparin/warfarin therapy. A sub-analysis of the AMPLIFY trial

artículo científico publicado en 2015

Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism

artículo científico publicado en 2017

Edoxaban for treatment of venous thromboembolism in patients with cancer. Rationale and design of the Hokusai VTE-cancer study.

artículo científico publicado en 2015

Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial.

artículo científico publicado en 2016

Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model

artículo científico publicado en 2018

Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: The FOXTROT Randomized Clinical Trial

scientific article published on 01 January 2020

Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers

artículo científico publicado en 2004

Emerging anticoagulant drugs

artículo científico publicado en 2003

Emerging anticoagulant strategies

artículo científico publicado en 2016

Emerging anticoagulants for the treatment of venous thromboembolism

artículo científico publicado en 2006

Emerging themes in the treatment of venous thromboembolism

artículo científico publicado en 2006

Emerging therapies for stroke prevention in atrial fibrillation

artículo científico publicado en 2005

Establishing Therapeutic Equivalence of Complex Pharmaceuticals: The Case of Dabigatran

scientific article published on 05 June 2018

Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents

artículo científico publicado en 2003

Evaluation of direct oral anticoagulants in superficial-vein thrombosis - Authors' reply.

artículo científico publicado en 2017

Evidence that both exosites on thrombin participate in its high affinity interaction with fibrin

artículo científico publicado en 2003

Evolving Treatments for Arterial and Venous Thrombosis: Role of the Direct Oral Anticoagulants

artículo científico publicado en 2016

Evolving use of new oral anticoagulants for treatment of venous thromboembolism

artículo científico publicado en 2014

Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin-Thrombomodulin Complex.

artículo científico publicado en 2017

Expanding use of new oral anticoagulants

artículo científico publicado en 2014

Expert Consensus Guidelines for Stocking of Antidotes in Hospitals That Provide Emergency Care.

artículo científico publicado en 2017

Extended anticoagulant therapy in venous thromboembolism: a balanced, fractional factorial, clinical vignette-based study

artículo científico publicado en 2019

Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study

artículo científico publicado en 2016

Extended treatment of venous thromboembolism

artículo científico publicado en 2013

Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post-hoc analysis of the Hokusai-VTE Cancer study

scientific article published on 25 July 2019

Factor XI and factor XII as targets for new anticoagulants

artículo científico publicado en 2016

Factor XI antisense oligonucleotide for prevention of venous thrombosis

artículo científico publicado en 2014

Factor XI antisense oligonucleotide for venous thrombosis

scientific article published on 01 April 2015

Factor XIII Prevents Pulmonary Emboli in Mice by Stabilizing Deep Vein Thrombi

artículo científico publicado en 2019

Factor Xa and thrombin as targets for new oral anticoagulants

scientific article published on 01 January 2011

Factors XI and XII as Targets for New Anticoagulants

scientific article published on 24 February 2017

Four-factor prothrombin complex concentrate for urgent reversal of vitamin K antagonists in patients with major bleeding

artículo científico publicado en 2013

G-protein-coupled receptors as signaling targets for antiplatelet therapy

artículo científico publicado en 2008

Gastrointestinal Bleeding With Edoxaban Versus Warfarin: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis In Myocardial Infarction)

scientific article published on 01 May 2018

Gastrointestinal bleeding with the new oral anticoagulants--defining the issues and the management strategies

artículo científico publicado en 2013

General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease.

artículo científico publicado en 2013

Genetics of coagulation: what the cardiologist needs to know

artículo científico

Global Anticoagulant Registry in the Field - Venous Thromboembolism (GARFIELD-VTE). Rationale and design

artículo científico publicado en 2016

Global public awareness about atrial fibrillation

artículo científico publicado en 2017

Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity ⬇️

artículo científico publicado el 11 de noviembre de 2003

Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group

artículo científico publicado en 2012

HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions

scientific article published on 15 September 2009

HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase

artículo científico

HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase

artículo científico publicado en 2015

Healthcare resource utilization in patients receiving idarucizumab for reversal of dabigatran anticoagulation due to major bleeding, urgent surgery, or procedural interventions: interim results from the RE-VERSE AD™ study

artículo científico publicado en 2016

Heparan sulfate: antithrombotic or not?

artículo científico publicado en 2003

Heparin and angiogenesis: size matters!

artículo científico publicado en 2003

Heparin synergistically enhances interleukin-11 signaling through up-regulation of the MAPK pathway

scientific article published on 23 May 2006

Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway

artículo científico publicado en 2015

Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation ⬇️

artículo científico publicado el 8 de febrero de 2011

Histidine-rich glycoprotein binds fibrin(ogen) with high affinity and competes with thrombin for binding to the gamma'-chain

artículo científico

Hospitalized COVID-19 Patients and Venous Thromboembolism: A Perfect Storm

artículo científico publicado en 2020

Hypercoagulability and COVID-19 associated hypoxemic respiratory failure: Mechanisms and emerging management paradigms

artículo científico publicado en 2020

Hypercoagulable states

artículo científico publicado en 2010

Hypercoagulable states

artículo científico publicado en 2011

Idarucizumab for Dabigatran Reversal

artículo científico publicado en 2015

Idarucizumab for Dabigatran Reversal - Full Cohort Analysis

artículo científico publicado en 2017

Idarucizumab for dabigatran overdose.

artículo científico publicado en 2016

Idarucizumab: The Antidote for Reversal of Dabigatran

artículo científico publicado en 2015

Identification and characterization of a factor Va-binding site on human prothrombin fragment 2

scientific article published on 21 February 2019

Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion

scientific journal article

Idrabiotaparinux treatment for venous thromboembolism

artículo científico publicado en 2011

Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial

artículo científico publicado en 2017

Impact of concomitant antiplatelet therapy on the efficacy and safety of DOACs for acute venous thromboembolism: systematic review and meta-analysis

artículo científico publicado en 2020

Importance of family history as a risk factor for venous thromboembolism.

artículo científico publicado en 2011

In high-risk patients with arthritis and previous upper GI bleeding, celecoxib vs naproxen reduced recurrent bleeding.

artículo científico publicado en 2017

In the presence of phospholipids, glycosaminoglycans potentiate factor Xa-mediated protein C activation by modulating factor Xa activity

artículo científico publicado en 2007

In vitro comparison of the effect of heparin, enoxaparin and fondaparinux on tests of coagulation

artículo científico publicado en 2002

Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: A Population-Based Cohort Study

artículo científico publicado en 2019

Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation

artículo científico publicado en 2015

Incorporation of fragment X into fibrin clots renders them more susceptible to lysis by plasmin

scientific article published on 01 April 2006

Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen.

artículo científico publicado en 2001

Inferior vena cava ligation rapidly induces tissue factor expression and venous thrombosis in rats

artículo científico publicado en 2009

Influence of model-predicted rivaroxaban exposure and patient characteristics on efficacy and safety outcomes in patients with acute coronary syndrome

artículo científico publicado en 2019

Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial

artículo científico publicado en 2008

Inhibition of osteolytic bone metastasis by unfractionated heparin

artículo científico publicado en 2008

Initial treatment of venous thromboembolism

scientific article published on 01 September 2006

Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome

scientific article published on 17 July 2014

Isolated Distal Deep Vein Thrombosis: Perspectives from the GARFIELD-VTE Registry

artículo científico publicado en 2019

Laboratory Monitoring of Non-Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation: A Review

artículo científico publicado en 2017

Letter to the Editor: Managing Dabigatran-Related Bleeding

artículo científico publicado en 2016

Leukocyte urokinase plasminogen activator receptor and PSGL1 play a role in endogenous arterial fibrinolysis

artículo científico publicado en 2009

Life-threatening thrombosis in mice with targeted Arg48-to-Cys mutation of the heparin-binding domain of antithrombin.

artículo científico publicado en 2003

Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial

artículo científico publicado en 2018

Localization of heparin and low-molecular-weight heparin in the rat kidney

artículo científico publicado en 2004

Long range communication between exosites 1 and 2 modulates thrombin function

artículo científico publicado en 2009

Long range communication between exosites 1 and 2 modulates thrombin function.

artículo científico publicado en 2015

Long term risk of symptomatic recurrent venous thromboembolism after discontinuation of anticoagulant treatment for first unprovoked venous thromboembolism event: systematic review and meta-analysis

artículo científico publicado en 2019

Long-Term Management of Venous Thromboembolism: Lessons from EINSTEIN CHOICE and Other Extension Trials

scientific article published on 26 February 2019

Low-dose warfarin in rehabilitating stroke survivors

artículo científico publicado en 2002

Lubricant-Infused PET Grafts with Built-In Biofunctional Nanoprobes Attenuate Thrombin Generation and Promote Targeted Binding of Cells

scientific article published on 27 November 2019

Lubricant-Infused Surfaces with Built-In Functional Biomolecules Exhibit Simultaneous Repellency and Tunable Cell Adhesion

artículo científico publicado en 2018

Lys 42/43/44 and Arg 12 of thrombin-activable fibrinolysis inhibitor comprise a thrombomodulin exosite essential for its antifibrinolytic potential.

artículo científico publicado en 2017

MAA868 locks factor XIa in a zymogen-like state

scientific article published on 01 March 2019

Management of venous thromboembolism: present and future

artículo científico publicado en 2004

Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease

artículo científico publicado en 2014

Measuring Dabigatran Levels: What Tests Are Available and What Still Needs to Be Done?

artículo científico publicado en 2017

Mechanism of catalysis of inhibition of factor IXa by antithrombin in the presence of heparin or pentasaccharide

artículo científico publicado en 2003

Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo

artículo científico publicado en 2011

Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex ⬇️

artículo científico publicado el 14 de abril de 2003

Mechanistic Basis for the Differential Effects of Rivaroxaban and Apixaban on Global Tests of Coagulation

artículo científico publicado en 2018

Meeting the unmet needs in anticoagulant therapy

artículo científico publicado en 2010

Modes and consequences of thrombin's interaction with fibrin

artículo científico publicado en 2004

Modification of polyurethane with polyethylene glycol-corn trypsin inhibitor for inhibition of factor Xlla in blood contact

scientific article published on 08 May 2012

More on Acutely Injured Patients Receiving Dabigatran

artículo científico publicado en 2012

Mortality Risk Profiles for Sepsis: A Novel Longitudinal and Multivariable Approach

scientific article published on 01 August 2019

Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation

artículo científico publicado en 2008

NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank

artículo científico publicado en 2016

Neutrophil extracellular traps promote thrombin generation through platelet-dependent and platelet-independent mechanisms

artículo científico publicado en 2014

New Anticoagulants

artículo científico publicado en 2010

New Anticoagulants: Moving Beyond the Direct Oral Anticoagulants

artículo científico publicado en 2020

New and Emerging Anticoagulant Therapies for Venous Thromboembolism ⬇️

artículo científico publicado el 1 de abril de 2010

New anticoagulant drugs: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

artículo científico publicado en 2004

New anticoagulant therapy

artículo científico publicado en 2005

New anticoagulants

artículo científico publicado en 2004

New anticoagulants

scientific article published on 01 December 2003

New anticoagulants for treatment of venous thromboembolism

artículo científico publicado en 2008

New anticoagulants for treatment of venous thromboembolism.

artículo científico publicado en 2004

New anticoagulants: an update.

artículo científico publicado en 2004

New anticoagulants: beyond heparin, low-molecular-weight heparin and warfarin

artículo científico publicado en 2005

New anticoagulants: current status and future potential

artículo científico publicado en 2003

New antithrombotic drugs: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)

scientific article published on 01 June 2008

New antithrombotic drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

artículo científico publicado en 2012

New developments in anticoagulants: Past, present and future

artículo científico publicado en 2017

New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper

artículo científico publicado en 2012

New oral anticoagulants in development

artículo científico publicado en 2009

New oral anticoagulants: a view from the laboratory

artículo científico

New oral anticoagulants: which one should my patient use?

artículo científico publicado en 2012

Non-vitamin K antagonist oral anticoagulants (NOACs): No longer new or novel

artículo científico publicado en 2014

Non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients with bioprosthetic valves

scientific article published on 23 May 2018

Non-vitamin K antagonist oral anticoagulants: an appeal for consensus on terminology

artículo científico publicado en 2014

North American Thrombosis Forum, AF Action Initiative Consensus Document

artículo científico publicado en 2016

Novel antithrombotic strategies for treatment of venous thromboembolism

artículo científico publicado en 2020

Novel antithrombotic therapies for the prevention of stroke in patients with atrial fibrillation

artículo científico publicado en 2004

Novel oral anticoagulants and reversal agents: Considerations for clinical development

artículo científico

Novel oral anticoagulants in gastroenterology practice

artículo científico publicado en 2013

OASIS-6: should patients with acute ST-segment elevation myocardial infarction be treated with fondaparinux?

artículo científico publicado en 2006

Obituary for Dr. Clive Kearon

artículo científico publicado en 2020

Oncogenes as regulators of tissue factor expression in cancer: implications for tumor angiogenesis and anti-cancer therapy

artículo científico publicado en 2004

Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis

artículo científico publicado en 2004

Optimizing the safety of treatment for venous thromboembolism in the era of direct oral anticoagulants.

artículo científico publicado en 2016

Oral anticoagulants in coronary heart disease (Section IV). Position paper of the ESC Working Group on Thrombosis - Task Force on Anticoagulants in Heart Disease

artículo científico publicado en 2016

Oral apixaban for the treatment of acute venous thromboembolism

artículo científico publicado en 2013

Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement. A randomised double-blind dose-response study

artículo científico publicado en 2010

Oral direct factor Xa inhibitors

artículo científico

Orally active direct thrombin inhibitors

artículo científico publicado en 2003

Otamixaban in acute coronary syndromes

artículo científico publicado en 2009

Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study.

artículo científico publicado en 2017

Overview of Therapeutic Approaches for Cholesterol Lowering and Attenuation of Thrombosis for Prevention of Atherothrombosis

scientific article published on 01 February 2019

Overview of the new oral anticoagulants: opportunities and challenges

artículo científico

Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

artículo científico publicado en 2008

Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

artículo científico publicado en 2012

Patients with severe sepsis vary markedly in their ability to generate activated protein C

scientific article published on 19 August 2004

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial

scientific article published on 03 May 2018

Periprocedural Management and Approach to Bleeding in Patients Taking Dabigatran

article

Periprocedural management of new oral anticoagulants in patients undergoing atrial fibrillation ablation

artículo científico

Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research

artículo científico publicado en 2020

Pharmacology and clinical potential of direct thrombin inhibitors

artículo científico publicado en 2005

Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome.

artículo científico publicado en 2014

Plasma fibronectin supports hemostasis and regulates thrombosis

artículo científico publicado en 2014

Platelet polyphosphate: the long and the short of it.

artículo científico publicado en 2017

Post-Discharge Prophylaxis With Rivaroxaban Reduces Fatal and Major Thromboembolic Events in Medically Ill Patients

artículo científico publicado en 2020

Potential of new anticoagulants in patients with cancer

artículo científico publicado en 2010

Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants

artículo científico publicado en 2015

Prevention and treatment of venous thromboembolism during pregnancy

artículo científico publicado en 2009

Prevention of thromboembolic complications in patients with superficial-vein thrombosis given rivaroxaban or fondaparinux: the open-label, randomised, non-inferiority SURPRISE phase 3b trial

artículo científico publicado en 2017

Procoagulants for management of bleeding with the new oral anticoagulants

artículo científico publicado en 2013

Prognostic utility and characterization of cell-free DNA in patients with severe sepsis

artículo científico publicado en 2012

Prosthetic Heart Valve Thrombosis

artículo científico publicado en 2016

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation ⬇️

artículo científico publicado el 5 de agosto de 2010

Randomized phase 2 trial comparing JNJ-9375, a thrombin-directed antibody, with apixaban for prevention of venous thrombosis

artículo científico publicado en 2019

Randomized, blinded trial comparing fondaparinux with unfractionated heparin in patients undergoing contemporary percutaneous coronary intervention: Arixtra Study in Percutaneous Coronary Intervention: a Randomized Evaluation (ASPIRE) Pilot Trial

artículo científico publicado en 2005

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants

artículo científico publicado en 2017

Recent advances in understanding, diagnosing and treating venous thrombosis

artículo científico publicado en 2020

Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study

artículo científico publicado en 2016

Reduced plasminogen binding and delayed activation render γ'-fibrin more resistant to lysis than γA-fibrin

artículo científico publicado en 2014

Research and Practice in Thrombosis and Haemostasis - a new ISTH publishing platform for the global thrombosis and hemostasis community.

artículo científico publicado en 2017

Response by Chan and Weitz to Letter Regarding Article, "Antithrombotic Agents: New Directions in Antithrombotic Therapy"

artículo científico publicado en 2019

Response by Weitz and Eikelboom to Letter Regarding Article, "Urgent Need to Measure Effects of Direct Oral Anticoagulants".

artículo científico publicado en 2016

Reversal agents for non-vitamin K antagonist oral anticoagulants

artículo científico publicado en 2018

Reversal of Direct Oral Anticoagulants: Current Status and Future Directions

artículo científico publicado en 2017

Risk of recurrent venous thromboembolism according to baseline risk factor profiles

artículo científico publicado en 2018

Rivaroxaban and Dabigatran for Suppression of Mechanical Heart Valve-Induced Thrombin Generation

artículo científico publicado en 2019

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source

article published in 2018

Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness

artículo científico publicado en 2018

Rivaroxaban for prevention and treatment of venous thromboembolism

scientific article published on 19 February 2019

Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: Design of the NAVIGATE ESUS randomized trial

article

Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism

artículo científico publicado en 2017

Rivaroxaban plus aspirin for cardiovascular protection: Rationale for the vascular dose and dual pathway inhibition

scientific article published on 23 October 2019

Role of phenotypic and genetic testing in managing clopidogrel therapy

artículo científico publicado en 2014

Role of the tissue factor pathway in the biology of tumor initiating cells.

artículo científico publicado en 2010

Screening and Diagnostic Clinical Algorithm for Paroxysmal Nocturnal Hemoglobinuria: Expert Consensus.

artículo científico publicado en 2018

Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa.

artículo científico publicado en 2017

Selective D-dimer testing for diagnosis of a first suspected episode of deep venous thrombosis: a randomized trial.

artículo científico publicado en 2013

Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits.

artículo científico publicado en 2014

Selective factor Xa inhibition for thromboprophylaxis

artículo científico publicado en 2008

Should Warfarin Be Restarted After Warfarin-Associated Intracranial Hemorrhage?

article published in 2012

Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants

artículo científico publicado en 2020

Spotlight on unmet needs in stroke prevention: The PIONEER AF-PCI, NAVIGATE ESUS and GALILEO trials

artículo científico publicado en 2016

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

artículo científico publicado en 2013

Subtle differences in commercial heparins can have serious consequences for cardiopulmonary bypass patients: A randomized controlled trial

artículo científico publicado en 2012

Surface modification with polyethylene glycol-corn trypsin inhibitor conjugate to inhibit the contact factor pathway on blood-contacting surfaces.

artículo científico publicado en 2011

Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease

scientific article published on 01 February 2019

Targeted gene sequencing identifies variants in the protein C and endothelial protein C receptor genes in patients with unprovoked venous thromboembolism

artículo científico publicado en 2013

The MARINER trial of rivaroxaban after hospital discharge for medical patients at high risk of VTE

article

The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V-Special Situations

scientific article published on 31 December 2018

The Postthrombotic Syndrome: Evidence-Based Prevention, Diagnosis, and Treatment Strategies

article

The blood compatibility challenge. Part 1: Blood-contacting medical devices: The scope of the problem

scientific article published on 18 June 2019

The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand

artículo científico publicado en 2013

The contact activation system as a potential therapeutic target in patients with COVID‐19

artículo científico publicado en 2020

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways

artículo científico publicado en 2002

The mTORC pathway in the antiphospholipid syndrome.

artículo científico publicado en 2014

The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients

artículo científico publicado en 2018

The real decoy: an antidote for factor Xa-directed anticoagulants

artículo científico publicado en 2013

The status of new anticoagulants

artículo científico publicado en 2006

Theme 3: Non-invasive management of (recurrent) venous thromboembolism (VTE) and post thrombotic syndrome (PTS).

artículo científico publicado en 2015

Therapeutic strategies for thrombosis: new targets and approaches

scientific article published on 04 March 2020

Thrombophilia and new anticoagulant drugs

artículo científico publicado en 2004

Thromboprophylaxis in surgical patients.

artículo científico publicado en 2003

Thromboprophylaxis with Rivaroxaban in Acutely Ill Medical Patients with Renal Impairment: Insights from the MAGELLAN and MARINER Trials

artículo científico publicado en 2020

Thrombosis: a major contributor to global disease burden

artículo científico publicado en 2014

Timing the First Postoperative Dose of Anticoagulants: Lessons Learned From Clinical Trials

artículo científico

Transition from apixaban to warfarin--addressing excess stroke, systemic embolism, and major bleeding

artículo científico publicado en 2014

Translational success stories: development of direct thrombin inhibitors

artículo científico publicado en 2012

Treatment Challenges in Venous Thromboembolism: An Appraisal of Rivaroxaban Studies

scientific article published on 22 March 2018

Trends in Prescribing Oral Anticoagulants in Canada, 2008-2014.

artículo científico publicado en 2015

Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism. Rationale for and design of the EINSTEIN CHOICE study

artículo científico publicado en 2015

Unanswered questions in venous thromboembolism

artículo científico publicado en 2009

Update on heparin: what do we need to know?

artículo científico publicado en 2010

Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry

artículo científico publicado en 2019

Urgent Need to Measure Effects of Direct Oral Anticoagulants.

artículo científico publicado en 2016

Variation in the Association between Antineoplastic Therapies and Venous Thromboembolism in Patients with Active Cancer

scientific article published on 05 May 2020

Venous thrombosis

artículo científico publicado en 2015

Vimentin exposed on activated platelets and platelet microparticles localizes vitronectin and plasminogen activator inhibitor complexes on their surface

artículo científico publicado en 2001

Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease

scientific article published on 14 November 2013

Vorapaxar, combination antiplatelet therapy, and stroke

artículo científico publicado en 2014

Warfarin after bioprosthetic aortic valve implantation

artículo científico publicado en 2012

Ximelagatran: the first oral direct thrombin inhibitor

artículo científico publicado en 2004

Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation

artículo científico publicado en 2015

Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure

artículo científico publicado en 2015

Zinc: an important cofactor in haemostasis and thrombosis

scientific article published on 10 January 2013

Zn2+ mediates high affinity binding of heparin to the αC domain of fibrinogen

artículo científico publicado en 2013

An evaluation of D-dimer in the diagnosis of pulmonary embolism: a randomized trial

artículo científico publicado en 2006

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