Lista de obras - Sebastiano Pasqualato - Dominio Público Uruguay

Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae

artículo científico publicado en 2006

Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication

artículo científico publicado en 2002

Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein

artículo científico publicado en 2005

Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions

artículo científico publicado en 2021

Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation

artículo científico publicado en 2014

Fast native-SAD phasing for routine macromolecular structure determination

artículo científico publicado en 2015

Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

scientific article published on 17 May 2019

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex

artículo científico publicado en 2008

Mechanism of domain closure of Sec7 domains and role in BFA sensitivity

artículo científico publicado en 2002

Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization

artículo científico publicado en 2014

Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

artículo científico publicado en 2010

Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers

scientific article published on 01 October 2020

Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex

artículo científico publicado en 2015

Recombinant and Truncated Tetanus Neurotoxin Light Chain: Cloning, Expression, Purification, and Proteolytic Activity

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

artículo científico publicado en 2020

Structural and functional framework for the autoinhibition of Nedd4-family ubiquitin ligases

artículo científico publicado en 2014

Structure of Arf6-GDP suggests a basis for guanine nucleotide exchange factors specificity

artículo científico publicado en 2000

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming

artículo científico publicado en 2013

Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry

artículo científico publicado en 2001

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

artículo científico publicado en 2011

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

artículo científico publicado en 2010

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

artículo científico publicado en 2010

The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus end.

artículo científico publicado en 2011

The pseudo GTPase CENP-M drives human kinetochore assembly

artículo científico publicado en 2014

The structural GDP/GTP cycle of Rab11 reveals a novel interface involved in the dynamics of recycling endosomes

artículo científico publicado en 2004

The structural GDP/GTP cycle of human Arf6

artículo científico publicado en 2001

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.

artículo científico publicado en 2017

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.

artículo científico publicado en 2017

Lista de obras de Sebastiano Pasqualato

Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae

Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication

Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein

Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions

Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation

Fast native-SAD phasing for routine macromolecular structure determination

Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex

Mechanism of domain closure of Sec7 domains and role in BFA sensitivity

Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization

Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping

Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers

Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex

Recombinant and Truncated Tetanus Neurotoxin Light Chain: Cloning, Expression, Purification, and Proteolytic Activity

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

Structural and functional framework for the autoinhibition of Nedd4-family ubiquitin ligases

Structure of Arf6-GDP suggests a basis for guanine nucleotide exchange factors specificity

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming

Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

The MIS12 complex is a protein interaction hub for outer kinetochore assembly

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

The Ndc80 loop region facilitates formation of kinetochore attachment to the dynamic microtubule plus end.

The pseudo GTPase CENP-M drives human kinetochore assembly

The structural GDP/GTP cycle of Rab11 reveals a novel interface involved in the dynamics of recycling endosomes

The structural GDP/GTP cycle of human Arf6

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.