Lista de obras - Alexis Nzila - Dominio Público Uruguay

2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials

artículo científico publicado en 2005

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

artículo científico publicado en 2014

A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers ⬇️

artículo científico publicado el 16 de marzo de 2011

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

artículo científico publicado en 2012

Anticancer agents against malaria: time to revisit?

artículo científico publicado en 2010

Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes

artículo científico publicado en 2012

Antimalarial chemotherapy: young guns or back to the future? ⬇️

artículo científico publicado el 1 de noviembre de 2003

Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria

artículo científico publicado en 2007

Baseline In Vitro Activities of the Antimalarials Pyronaridine and Methylene Blue against Plasmodium falciparum Isolates from Kenya ⬇️

artículo científico publicado el 28 de noviembre de 2011

Bioaugmentation: An Emerging Strategy of Industrial Wastewater Treatment for Reuse and Discharge

artículo científico publicado en 2016

Biodegradation of high-molecular-weight polycyclic aromatic hydrocarbons under anaerobic conditions: Overview of studies, proposed pathways and future perspectives

artículo científico publicado en 2018

Biogenic Synthesis and Characterization of Chitosan-CuO Nanocomposite and Evaluation of Antibacterial Activity against Gram-Positive and -Negative Bacteria

artículo científico publicado en 2022

Biotransformation and biocatalysis: roles and applications in the discovery of antimalarials

artículo científico

Characterisation and microbial community analysis of lipid utilising microorganisms for biogas formation

scientific article published on 08 November 2019

Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition

artículo científico publicado en 2010

Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987--2006

artículo científico publicado en 2008

Characterization of aerobic oil and grease-degrading bacteria in wastewater

artículo científico publicado en 2016

Chemosensitization of Plasmodium falciparum by probenecid in vitro

artículo científico publicado en 2003

Chloroquine resistance before and after its withdrawal in Kenya

artículo científico publicado en 2009

Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy ⬇️

artículo científico publicado el 9 de febrero de 2012

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

artículo científico publicado en 2005

Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium

artículo científico publicado en 2005

Current Status of and Future Perspectives in Bacterial Degradation of Benzo[a]pyrene

artículo científico publicado en 2020

Current Status of the Degradation of Aliphatic and Aromatic Petroleum Hydrocarbons by Thermophilic Microbes and Future Perspectives

artículo científico publicado en 2018

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

artículo científico publicado en 2011

Degradation of benzo[a]pyrene by halophilic bacterial strain Staphylococcus haemoliticus strain 10SBZ1A

artículo científico publicado en 2021

Drug Repositioning in the Treatment of Malaria and TB ⬇️

artículo científico publicado el 1 de septiembre de 2011

Drugs for the treatment of malaria in the Kingdom of Saudi Arabia

artículo científico publicado en 2013

Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer

artículo científico publicado en 2008

Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure

artículo científico publicado en 2012

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

artículo científico publicado en 2013

Genomic epidemiology of the current wave of artemisinin resistant malaria

scholarly article by Roberto Amato et al published 22 May 2015 in bioRxiv

Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate

artículo científico

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum

artículo científico publicado en 2004

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

artículo científico publicado en 2009

In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya

artículo científico publicado en 2010

In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation

artículo científico publicado en 2009

In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid

artículo científico publicado en 2009

In vitro selection of Plasmodium falciparum drug-resistant parasite lines

artículo científico publicado en 2009

In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa

artículo científico publicado en 2009

Inhibitors of de novo folate enzymes in Plasmodium falciparum

artículo científico publicado en 2006

Malaria in the Era of Food Fortification With Folic Acid

artículo científico publicado en 2016

Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species

artículo científico publicado en 2009

Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax ⬇️

artículo científico publicado en 2010

Mini review: Update on bioaugmentation in anaerobic processes for biogas production

artículo científico publicado en 2016

Modulators of the efficacy and toxicity of drugs in malaria treatment

artículo científico publicado en 2010

Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa

artículo científico publicado en 2003

Piperaquine and Lumefantrine resistance in Plasmodium berghei ANKA associated with increased expression of Ca2+/H+ antiporter and glutathione associated enzymes.

artículo científico publicado en 2014

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation

artículo científico publicado en 2013

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

artículo científico publicado en 2014

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay

artículo científico publicado en 2011

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

artículo científico publicado en 2010

Preparation of Silver/Chitosan Nanofluids Using Selected Plant Extracts: Characterization and Antimicrobial Studies Against Gram-Positive and Gram-Negative Bacteria

scientific article published on 01 April 2020

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.

scientific article published on 30 September 2013

Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern S

artículo científico publicado en 2003

The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya

artículo científico publicado en 2014

The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters

artículo científico publicado en 2011

The past, present and future of antifolates in the treatment of Plasmodium falciparum infection

artículo científico publicado en 2006

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

artículo científico publicado en 2004

Update on genetic markers of quinine resistance in Plasmodium falciparum

scientific article published on February 2011

Update on the cometabolism of organic pollutants by bacteria ⬇️

artículo científico publicado el 6 de abril de 2013

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates

artículo científico publicado en 2014

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?

artículo científico publicado en 2005

Lista de obras de Alexis Nzila

2,4-diaminopteridine-based compounds as precursors for de novo synthesis of antifolates: a novel class of antimalarials

A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya

A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers ⬇️

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

Anticancer agents against malaria: time to revisit?

Antimalarial activity of isoquine against Kenyan Plasmodium falciparum clinical isolates and association with polymorphisms in pfcrt and pfmdr1 genes

Antimalarial chemotherapy: young guns or back to the future? ⬇️

Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria

Baseline In Vitro Activities of the Antimalarials Pyronaridine and Methylene Blue against Plasmodium falciparum Isolates from Kenya ⬇️

Bioaugmentation: An Emerging Strategy of Industrial Wastewater Treatment for Reuse and Discharge

Biodegradation of high-molecular-weight polycyclic aromatic hydrocarbons under anaerobic conditions: Overview of studies, proposed pathways and future perspectives

Biogenic Synthesis and Characterization of Chitosan-CuO Nanocomposite and Evaluation of Antibacterial Activity against Gram-Positive and -Negative Bacteria

Biotransformation and biocatalysis: roles and applications in the discovery of antimalarials

Characterisation and microbial community analysis of lipid utilising microorganisms for biogas formation

Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition

Characteristics of Plasmodium falciparum dhfr haplotypes that confer pyrimethamine resistance, Kilifi, Kenya, 1987--2006

Characterization of aerobic oil and grease-degrading bacteria in wastewater

Chemosensitization of Plasmodium falciparum by probenecid in vitro

Chloroquine resistance before and after its withdrawal in Kenya

Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy ⬇️

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy

Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium

Current Status of and Future Perspectives in Bacterial Degradation of Benzo[a]pyrene

Current Status of the Degradation of Aliphatic and Aromatic Petroleum Hydrocarbons by Thermophilic Microbes and Future Perspectives

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast

Degradation of benzo[a]pyrene by halophilic bacterial strain Staphylococcus haemoliticus strain 10SBZ1A

Drug Repositioning in the Treatment of Malaria and TB ⬇️

Drugs for the treatment of malaria in the Kingdom of Saudi Arabia

Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer

Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure

Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya

Genomic epidemiology of the current wave of artemisinin resistant malaria

Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.

In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya

In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation

In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid

In vitro selection of Plasmodium falciparum drug-resistant parasite lines

In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa

Inhibitors of de novo folate enzymes in Plasmodium falciparum

Malaria in the Era of Food Fortification With Folic Acid

Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species

Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax ⬇️

Mini review: Update on bioaugmentation in anaerobic processes for biogas production

Modulators of the efficacy and toxicity of drugs in malaria treatment

Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa

Piperaquine and Lumefantrine resistance in Plasmodium berghei ANKA associated with increased expression of Ca2+/H+ antiporter and glutathione associated enzymes.

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay

Preclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug Candidate

Preparation of Silver/Chitosan Nanofluids Using Selected Plant Extracts: Characterization and Antimicrobial Studies Against Gram-Positive and Gram-Negative Bacteria

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.

Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern S

The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya

The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters

The past, present and future of antifolates in the treatment of Plasmodium falciparum infection

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

Update on genetic markers of quinine resistance in Plasmodium falciparum

Update on the cometabolism of organic pollutants by bacteria ⬇️

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates

Why has the dihydrofolate reductase 164 mutation not consistently been found in Africa yet?