Lista de obras - Donatella Del Bufalo - Dominio Público Uruguay

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

scientific article published on 08 July 2014

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

artículo científico publicado en 2015

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

artículo científico publicado en 2017

Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.

artículo científico publicado en 2016

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

artículo científico publicado en 2011

BCL-XL overexpression promotes tumor progression-associated properties.

artículo científico publicado en 2017

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

artículo científico publicado en 2013

Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used.

artículo científico publicado en 2002

Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity.

artículo científico publicado en 2001

Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.

artículo científico publicado en 2005

CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.

artículo científico publicado en 2011

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.

artículo científico publicado en 2017

Detection of P-glycoprotein in the Golgi apparatus of drug-untreated human melanoma cells.

artículo científico publicado en 1998

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

artículo científico publicado en 2012

Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.

artículo científico publicado en 2014

Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer

artículo científico publicado en 2018

Endothelin-1 acts as a survival factor in ovarian carcinoma cells

artículo científico publicado en 2002

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

artículo científico publicado en 2002

Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.

artículo científico publicado en 2005

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

scientific article published on 16 September 2020

Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression.

artículo científico publicado en 2009

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

artículo científico publicado en 2009

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

artículo científico publicado en 2016

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

artículo científico publicado en 2014

Hypoxia-dependent drivers of melanoma progression

artículo científico publicado en 2021

Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.

artículo científico publicado en 2008

Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model.

artículo científico publicado en 2017

Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells.

artículo científico publicado en 2011

Involvement of RB gene family in tumor angiogenesis.

artículo científico publicado en 2006

Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma

artículo científico publicado en 2008

LMNA knock-down affects differentiation and progression of human neuroblastoma cells

artículo científico publicado en 2012

Lonidamine causes inhibition of angiogenesis-related endothelial cell functions

artículo científico publicado en 2004

Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.

artículo científico publicado en 1996

Lost in translation: bridging the gap between cancer research and effective therapies.

artículo científico publicado en 2011

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

artículo científico publicado en 2020

Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity

artículo científico publicado en 2017

Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression

artículo científico publicado en 2007

N-methylformamide affects spontaneous metastases of 3LL lines and increases natural killer activity of tumor-bearing mice

artículo científico publicado en 1990

N-methylformamide as a potential therapeutic approach in colon cancer.

artículo científico publicado en 1994

N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells.

artículo científico publicado en 1998

N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics.

artículo científico publicado en 2014

NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis

artículo científico publicado en 2016

Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain

artículo científico publicado en 2017

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression

artículo científico publicado en 2015

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

scientific article published on 21 February 2017

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

artículo científico publicado en 2018

Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin

artículo científico publicado en 1994

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma

scientific article published on 05 September 2019

Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clones

scientific article published on 01 May 2002

Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth

artículo científico publicado en 2013

Retracted: Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90

artículo científico publicado en 2010

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb

artículo científico publicado en 2018

Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization

artículo científico publicado en 2017

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

artículo científico publicado en 2017

TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.

artículo científico publicado en 2014

Targeting hypoxia in tumor: a new promising therapeutic strategy

scientific article published on 10 January 2020

Telomere dysfunction increases cisplatin and ecteinascidin-743 sensitivity of melanoma cells

artículo científico publicado en 2003

The Combination of the M2 Muscarinic Receptor Agonist and Chemotherapy Affects Drug Resistance in Neuroblastoma Cells

artículo científico publicado en 2020

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

artículo científico publicado en 2009

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

artículo científico publicado en 2012

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target

artículo científico publicado en 2016

The thiazole derivative CPTH6 impairs autophagy

artículo científico publicado en 2013

Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha

artículo científico publicado en 2010

Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

artículo científico publicado en 2004

Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

artículo científico publicado en 2003

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling

artículo científico publicado en 2014

ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells

artículo científico publicado en 2002

miR-211 and MITF modulation by Bcl-2 protein in melanoma cells.

artículo científico publicado en 2015

microRNA-378a-5p iS a novel positive regulator of melanoma progression

artículo científico publicado en 2020

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.

artículo científico publicado en 2001

tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells

artículo científico publicado en 2013

Lista de obras de Donatella Del Bufalo

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein.

Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer.

BCL-XL overexpression promotes tumor progression-associated properties.

BH4 domain of bcl-2 protein is required for its proangiogenic function under hypoxic condition.

Bcl-2 has differing effects on the sensitivity of breast cancer cells depending on the antineoplastic drug used.

Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity.

Bcl-2 overexpression in melanoma cells increases tumor progression-associated properties and in vivo tumor growth.

CPTH6, a thiazole derivative, induces histone hypoacetylation and apoptosis in human leukemia cells.

Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma.

Detection of P-glycoprotein in the Golgi apparatus of drug-untreated human melanoma cells.

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.

Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer

Endothelin-1 acts as a survival factor in ovarian carcinoma cells

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

Functional activity of CXCL8 receptors, CXCR1 and CXCR2, on human malignant melanoma progression.

Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Hypoxia-dependent drivers of melanoma progression

Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.

Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model.

Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells.

Involvement of RB gene family in tumor angiogenesis.

Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma

LMNA knock-down affects differentiation and progression of human neuroblastoma cells

Lonidamine causes inhibition of angiogenesis-related endothelial cell functions

Lonidamine induces apoptosis in drug-resistant cells independently of the p53 gene.

Lost in translation: bridging the gap between cancer research and effective therapies.

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages

Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity

Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression

N-methylformamide affects spontaneous metastases of 3LL lines and increases natural killer activity of tumor-bearing mice

N-methylformamide as a potential therapeutic approach in colon cancer.

N-methylformamide induces changes on adhesive properties and lung-colonizing potential of M14 melanoma cells.

N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics.

NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis

Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma

Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clones

Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth

Retracted: Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb

Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.

Targeting hypoxia in tumor: a new promising therapeutic strategy

Telomere dysfunction increases cisplatin and ecteinascidin-743 sensitivity of melanoma cells

The Combination of the M2 Muscarinic Receptor Agonist and Chemotherapy Affects Drug Resistance in Neuroblastoma Cells

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target

The thiazole derivative CPTH6 impairs autophagy

Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha

Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling

ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells

miR-211 and MITF modulation by Bcl-2 protein in melanoma cells.

microRNA-378a-5p iS a novel positive regulator of melanoma progression

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.

tert-Butylcarbamate-containing histone deacetylase inhibitors: apoptosis induction, cytodifferentiation, and antiproliferative activities in cancer cells