Filtros de búsqueda

Lista de obras de Thomas Quertermous

A TNF variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation

artículo científico publicado en 2013

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A long noncoding RNA protects the heart from pathological hypertrophy

artículo científico publicado en 2014

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

artículo científico publicado en 2007

Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure

artículo científico publicado en 2008

Admixture mapping of quantitative trait loci for blood lipids in African-Americans

artículo científico publicado en 2009

Advances in Transcriptomics: Investigating Cardiovascular Disease at Unprecedented Resolution

artículo científico publicado en 2018

Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts

artículo científico publicado en 2017

An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies

artículo científico publicado en 2010

An autosomal genome-wide scan for loci linked to pre-diabetic phenotypes in nondiabetic Chinese subjects from the Stanford Asia-Pacific Program of Hypertension and Insulin Resistance Family Study

artículo científico publicado en 2005

An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program

artículo científico publicado en 2005

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity

artículo científico publicado en 2016

Apelin decreases lipolysis via G(q), G(i), and AMPK-Dependent Mechanisms

artículo científico publicado en 2010

Apelin enhances directed cardiac differentiation of mouse and human embryonic stem cells

artículo científico publicado en 2012

Apelin is necessary for the maintenance of insulin sensitivity

artículo científico publicado en 2009

Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

artículo científico publicado en 2009

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

artículo científico publicado en 2008

Apelin-APJ signaling in retinal angiogenesis

artículo científico publicado en 2008

Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development

artículo científico publicado en 2013

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

artículo científico publicado en 2017

Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarction

artículo científico publicado en 2007

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study

artículo científico publicado en 2007

CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study

artículo científico

Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes

artículo científico publicado en 2011

Characterizing the admixed African ancestry of African Americans

artículo científico publicado en 2009

Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.

artículo científico publicado en 2010

Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease

artículo científico publicado en 2007

Circulating peptide prevents preeclampsia

artículo científico publicado en 2017

Clinical Utility of a Novel Coronary Heart Disease Risk‐Assessment Test to Further Classify Intermediate‐Risk Patients ⬇️

artículo científico publicado el 8 de agosto de 2013

Clinical interpretation and implications of whole-genome sequencing

artículo científico publicado en 2014

Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption

artículo científico publicado en 2012

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

artículo científico publicado en 2008

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Comparison of developmental endothelial locus-1 angiogenic factor with vascular endothelial growth factor in a porcine model of cardiac ischemia

artículo científico publicado en 2003

Coronary Artery Disease and Its Risk Factors: Leveraging Shared Genetics to Discover Novel Biology

artículo científico publicado en 2016

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation

artículo científico publicado en 2014

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment

artículo científico publicado en 2008

Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3).

artículo científico publicado en 2002

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

artículo científico publicado en 2010

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia

artículo científico publicado en 2004

Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli

artículo científico

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus

artículo científico publicado en 2013

Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension

artículo científico publicado en 2011

Dissecting the causal genetic mechanisms of coronary heart disease

artículo científico

Distribution of the number of false discoveries in large-scale family-based association testing with application to the association between PTPN1 and hypertension and obesity

artículo científico publicado en 2010

Effect of Common Genetic Variants of Growth Arrest-Specific 6 Gene on Insulin Resistance, Obesity and Type 2 Diabetes in an Asian Population

artículo científico publicado en 2015

Endogenous regulation of cardiovascular function by apelin-APJ.

artículo científico publicado en 2009

Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interaction

artículo científico publicado en 2010

Endothelial lipase is a major determinant of HDL level

artículo científico publicado en 2003

Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages

artículo científico publicado en 2007

Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice

artículo científico publicado en 2004

Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation

artículo científico publicado en 2004

Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice

artículo científico publicado en 2004

Endothelial lipase: a new lipase on the block

artículo científico publicado en 2002

Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development

artículo científico publicado en 2013

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

artículo científico publicado en 2016

Erratum to: Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

FGD5 mediates proangiogenic action of vascular endothelial growth factor in human vascular endothelial cells

artículo científico publicado en 2012

FGF-1 enhanced cardiogenesis in differentiating embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2.

artículo científico publicado en 2003

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

artículo científico publicado en 2008

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

artículo científico publicado en 2017

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details

artículo científico publicado en 2015

Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis

artículo científico publicado en 2007

Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci

scholarly article by Boxiang Liu et al published 18 August 2018 in American Journal of Human Genetics

Genetic epistasis of adiponectin and PPARgamma2 genotypes in modulation of insulin sensitivity: a family-based association study

artículo científico publicado en 2003

Genetic evidence of assortative mating in humans

scholarly article

Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population

artículo científico publicado en 2015

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology

artículo científico publicado en 2007

Genetic targeting of sprouting angiogenesis using Apln-CreER.

artículo científico publicado en 2015

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

artículo científico publicado en 2013

Genetic variation in the carbonyl reductase 3 gene confers risk of type 2 diabetes and insulin resistance: a potential regulator of adipogenesis

artículo científico publicado en 2012

Genetics and Genomics of Coronary Artery Disease

artículo científico publicado en 2016

Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium

artículo científico publicado en 2016

Genome-wide copy number variation analysis identified deletions in SFMBT1 associated with fasting plasma glucose in a Han Chinese population

artículo científico publicado en 2017

Genome-wide expression dynamics during mouse embryonic development reveal similarities to Drosophila development

artículo científico publicado en 2005

Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses

artículo científico

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis

artículo científico publicado en 2005

Glia maturation factor-gamma is preferentially expressed in microvascular endothelial and inflammatory cells and modulates actin cytoskeleton reorganization

artículo científico publicado en 2006

HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

artículo científico publicado en 2007

Hepatic proprotein convertases modulate HDL metabolism

scientific journal article

Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study

artículo científico publicado en 2007

High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults

artículo científico publicado en 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

IGF1 Gene Is Associated With Triglyceride Levels In Subjects With Family History Of Hypertension From The SAPPHIRe And TWB Projects.

artículo científico publicado en 2018

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2016

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

artículo científico publicado en 2011

Identification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2

artículo científico publicado en 2009

Identification of endothelial cell genes by combined database mining and microarray analysis

artículo científico publicado en 2003

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries

artículo científico publicado en 2003

Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins

artículo científico publicado en 2010

In vivo bioluminescence imaging of inducible nitric oxide synthase gene expression in vascular inflammation

artículo científico publicado en 2011

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure

artículo científico publicado en 2007

In vivo molecular MRI of cell survival and teratoma formation following embryonic stem cell transplantation into the injured murine myocardium

artículo científico publicado en 2011

Increased Bone Mass in Mice Lacking the Adipokine Apelin ⬇️

artículo científico publicado el 12 de abril de 2013

Increased expression of endothelial lipase in rat models of hypertension

artículo científico publicado en 2005

Increased rate of hair regrowth in mice with constitutive overexpression of Del1.

artículo científico publicado en 2007

Inducible and selective transgene expression in murine vascular endothelium

artículo científico publicado en 2002

Insulin resistance independently predicts the progression of coronary artery calcification

artículo científico publicado en 2009

Insulin resistance: regression and clustering

artículo científico publicado en 2014

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

artículo científico publicado en 2014

Interpreting whole-genome sequencing--reply

artículo científico publicado en 2014

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

artículo científico publicado en 2011

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program

artículo científico publicado en 2014

Load-dependent effects of apelin on murine cardiomyocytes

artículo científico publicado en 2017

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation

artículo científico publicado en 2012

Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp

artículo científico publicado en 2012

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

artículo científico publicado en 2013

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Metabolic syndrome and early-onset coronary artery disease: is the whole greater than its parts?

artículo científico publicado en 2006

MicroRNA-26a is a novel regulator of vascular smooth muscle cell function

artículo científico publicado en 2011

Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms

artículo científico publicado en 2004

Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function

artículo científico publicado en 2004

Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli

artículo científico publicado en 2006

Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.

artículo científico publicado en 2004

Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice

artículo científico publicado en 2016

Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1

article

Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del-1.

artículo científico publicado en 2003

Network analysis of human in-stent restenosis

artículo científico

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction

artículo científico publicado en 2003

Ontogeny of apelin and its receptor in the rodent gastrointestinal tract

artículo científico publicado en 2009

Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery

artículo científico publicado en 2005

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

artículo científico publicado en 2014

Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice

artículo científico publicado en 2015

Pancreatitis activates pancreatic apelin-APJ axis in mice ⬇️

artículo científico publicado el 16 de mayo de 2013

Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex

scientific article published on 06 September 2016

Pathway analysis of coronary atherosclerosis

artículo científico

Peroxisome proliferator-activated receptor gamma polymorphisms and coronary heart disease

artículo científico publicado en 2009

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells

artículo científico publicado en 2010

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

artículo científico publicado en 2016

Physical inactivity is an important lifestyle determinant of insulin resistance in hypertensive patients

artículo científico publicado en 2004

Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation

artículo científico publicado en 2005

Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease

article

Proteomic profiles of serum inflammatory markers accurately predict atherosclerosis in mice

artículo científico publicado en 2006

Racial variation in lipoprotein-associated phospholipase A₂ in older adults

artículo científico publicado en 2011

Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort

artículo científico publicado en 2012

Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis

artículo científico publicado en 2010

Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia

artículo científico publicado en 2009

Sagittal abdominal diameter is associated with insulin sensitivity in Chinese hypertensive patients and their siblings

artículo científico publicado en 2003

Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data

artículo científico publicado en 2015

Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease

artículo científico

Statin and beta-blocker therapy and the initial presentation of coronary heart disease

artículo científico publicado en 2006

Study of exonic variation identifies incremental information regarding lipid-related and coronary heart disease genes

artículo científico publicado en 2014

Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course

artículo científico publicado en 2015

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

scientific article published on 28 April 2008

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

artículo científico publicado en 2015

Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure

artículo científico publicado en 2015

TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression

article

Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivo

artículo científico publicado en 2003

Targeted inactivation of endothelial lipase attenuates lung allergic inflammation through raising plasma HDL level and inhibiting eosinophil infiltration

artículo científico publicado en 2009

Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment

artículo científico publicado en 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The adhesion molecule esam1 is a novel hematopoietic stem cell marker

artículo científico publicado en 2009

The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model

artículo científico publicado en 2013

The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation

artículo científico publicado en 2002

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

artículo científico publicado en 2005

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of data quality on the identification of complex disease genes: experience from the Family Blood Pressure Program

artículo científico publicado en 2006

The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe

artículo científico publicado en 2008

Therapeutic lymphangiogenesis with human recombinant VEGF-C.

artículo científico publicado en 2002

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population

artículo científico publicado en 2013

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

artículo científico publicado en 2013

Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation

artículo científico

Transcriptional profiling of the heart reveals chamber-specific gene expression patterns

artículo científico publicado en 2003

Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality

artículo científico publicado en 2008

Transcriptome-wide association studies: opportunities and challenges

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

artículo científico publicado en 2016

Tree-structured supervised learning and the genetics of hypertension

artículo científico publicado en 2004

Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program

artículo científico publicado en 2005

Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse

artículo científico publicado en 2010

Use of high throughput genomic tools for the study of endothelial cell biology

artículo científico publicado en 2003

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda