Lista de obras - Martina Müller-Nurasyid

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

artículo científico publicado en 2011

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

artículo científico publicado en 2012

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A regulatory variant in CCR6 is associated with susceptibility to antitopoisomerase-positive systemic sclerosis

artículo científico publicado en 2013

Analysis with the exome array identifies multiple new independent variants in lipid loci

artículo científico publicado en 2016

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

artículos científicos

Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases

artículo científico publicado en 2016

Association of early repolarization pattern on ECG with risk of cardiac and all-cause mortality: a population-based prospective cohort study (MONICA/KORA).

artículo científico publicado en 2010

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

scientific article published in Nature Communications

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Candidate Brocadiales dominates C, N and S cycling in anoxic groundwater of a pristine limestone-fracture aquifer

artículo científico publicado en 2016

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Common Genetic Polymorphisms and Haplotypes of Fibrinogen Alpha, Beta, and Gamma Chains Affect Fibrinogen Levels and the Response to Proinflammatory Stimulation in Myocardial Infarction Survivors

article

Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries

scientific article published on 10 December 2021

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common coding variant in SERPINA1 increases the risk for large artery stroke

artículo científico publicado en 2017

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 12q15 and 12q24 are associated with infant head circumference

artículo científico publicado en 2012

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

artículo científico publicado en 2014

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R

artículo científico publicado en 2014

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

artículo científico publicado en 2021

DNA variants, plasma levels and variability of C-reactive protein in myocardial infarction survivors: results from the AIRGENE study

DNA variants, plasma levels and variability of Interleukin-6 in myocardial infarction survivors: Results from the AIRGENE study

Deciphering the 8q24.21 association for glioma

artículo científico publicado en 2013

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests

artículo científico publicado en 2018

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

artículo científico publicado en 2013

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

scientific article published on 07 February 2020

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

artículo científico publicado en 2017

Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample

artículo científico publicado en 2008

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

artículo científico publicado en 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave

artículo científico publicado en 2017

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

artículo científico publicado en 2017

Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation

artículo científico publicado en 2020

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

artículo científico publicado en 2016

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in RBFOX3 are associated with sleep latency

artículo científico publicado en 2016

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes

artículo científico publicado en 2017

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

artículo científico publicado en 2017

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

artículo científico publicado en 2018

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2

artículo científico publicado en 2016

Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals

scientific article published on 01 July 2019

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

artículo científico publicado en 2013

Genome-wide association analysis identifies multiple loci related to resting heart rate

artículo científico publicado en 2010

Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions

artículo científico publicado en 2008

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

artículo científico publicado en 2019

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association studies of the PR interval in African Americans

artículo científico publicado en 2011

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus

artículo científico publicado en 2015

Genome-wide association study of PR interval

artículo científico publicado en 2010

Genome-wide association study of kidney function decline in individuals of European descent

artículo científico publicado en 2014

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Harmonization of study and reference data by PhaseLift: saving time when imputing study data

artículo científico publicado en 2014

Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease

artículo científico publicado en 2014

Heritability of young- and old-onset ischaemic stroke.

artículo científico publicado en 2015

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity

artículo científico publicado en 2016

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Incidence of complications related to catheter ablation of atrial fibrillation and atrial flutter: a nationwide in-hospital analysis of administrative data for Germany in 2014

scientific article published on 01 December 2018

Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

artículo científico publicado en 2010

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

artículo científico publicado en 2014

Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma

artículo científico publicado en 2019

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project

artículo científico publicado en 2011

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

artículo científico publicado en 2017

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

artículo científico publicado en 2014

Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach

artículo científico publicado en 2012

Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.

artículo científico publicado en 2013

META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies

artículo científico publicado en 2015

Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: Results from the MONICA/KORA Augsburg case-cohort study, 1984–2002

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

artículo científico publicado en 2019

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

artículo científico publicado en 2019

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

artículo científico publicado en 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

artículo científico publicado en 2012

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ethnic genome-wide association study for atrial fibrillation

article

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

artículo científico

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

No association of two functional polymorphisms in human ALOX15 with myocardial infarction

artículo científico publicado en 2008

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

artículo científico publicado en 2014

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

artículo científico publicado en 2014

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

artículo científico publicado en 2016

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

scientific article published on 09 November 2019

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Proteome data on the microbial microbiome of grasshopper feces

artículo científico publicado en 2016

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quantifying the contribution of genetic variants for survival phenotypes

article

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

artículo científico publicado en 2011

RANTES/CCL5 gene polymorphisms, serum concentrations, and incident type 2 diabetes: results from the MONICA/KORA Augsburg case–cohort study, 1984–2002

article

RL-SKAT: An Exact and Efficient Score Test for Heritability and Set Tests.

artículo científico publicado en 2017

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

artículo científico publicado en 2015

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

artículo científico publicado en 2021

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Repolarization Heterogeneity Measured With T-Wave Area Dispersion in Standard 12-Lead ECG Predicts Sudden Cardiac Death in General Population

artículo científico publicado en 2018

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients

article

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

scholarly article

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

artículo científico publicado en 2017

Lista de obras de Martina Müller-Nurasyid

52 Genetic Loci Influencing Myocardial Mass

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

A regulatory variant in CCR6 is associated with susceptibility to antitopoisomerase-positive systemic sclerosis

Analysis with the exome array identifies multiple new independent variants in lipid loci

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases

Association of early repolarization pattern on ECG with risk of cardiac and all-cause mortality: a population-based prospective cohort study (MONICA/KORA).

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Candidate Brocadiales dominates C, N and S cycling in anoxic groundwater of a pristine limestone-fracture aquifer

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Common Genetic Polymorphisms and Haplotypes of Fibrinogen Alpha, Beta, and Gamma Chains Affect Fibrinogen Levels and the Response to Proinflammatory Stimulation in Myocardial Infarction Survivors

Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common coding variant in SERPINA1 increases the risk for large artery stroke

Common variants associated with plasma triglycerides and risk for coronary artery disease

Common variants at 12q15 and 12q24 are associated with infant head circumference

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

DNA variants, plasma levels and variability of C-reactive protein in myocardial infarction survivors: results from the AIRGENE study

DNA variants, plasma levels and variability of Interleukin-6 in myocardial infarction survivors: Results from the AIRGENE study

Deciphering the 8q24.21 association for glioma

Defining the role of common variation in the genomic and biological architecture of adult human height

Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

Discovery and refinement of loci associated with lipid levels

Discovery of novel heart rate-associated loci using the Exome Chip

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Fifteen Genetic Loci Associated With the Electrocardiographic P Wave

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants in RBFOX3 are associated with sleep latency

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2

Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

Genome-wide association analysis identifies multiple loci related to resting heart rate

Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

Genome-wide association studies of the PR interval in African Americans

Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus

Genome-wide association study of PR interval

Genome-wide association study of kidney function decline in individuals of European descent

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Harmonization of study and reference data by PhaseLift: saving time when imputing study data

Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with progressive atherosclerosis and incident cardiovascular disease

Heritability of young- and old-onset ischaemic stroke.

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity