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Lista de obras de Jos Kleinjans

"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.

artículo científico publicado en 2016

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans

artículo científico publicado en 2012

A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure

artículo científico publicado en 2016

A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases

artículo científico publicado en 2018

A dictionary to identify small molecules and drugs in free text

artículo científico

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

artículo científico publicado en 2017

A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms

artículo científico publicado en 2001

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

artículo científico publicado en 2009

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

artículo científico publicado en 2019

Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma

artículo científico publicado en 2016

Altered vegetable intake affects pivotal carcinogenesis pathways in colon mucosa from adenoma patients and controls

scientific article published on 22 July 2004

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

artículo científico publicado en 2011

An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2011

Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid

artículo científico publicado en 2003

Assessing compound carcinogenicity in vitro using connectivity mapping

artículo científico publicado en 2013

Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.

artículo científico publicado en 2009

Associations Between Genome-wide Gene Expression and Ambient Nitrogen Oxides

artículo científico publicado en 2017

Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining

artículo científico publicado en 2010

Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining

artículo científico publicado en 2010

B[a]P-DNA adduct formation and induction of human epithelial lung cell transformation ⬇️

artículo científico publicado el 1 de enero de 1997

Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans

artículo científico publicado en 2015

Bioavailability of soil-adsorbed cadmium in orally exposed male rats

artículo científico publicado en 1997

Bioinformatics Methods for Interpreting Toxicogenomics Data

Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome

artículo científico publicado en 2016

Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes

artículo científico publicado en 2010

Birth weight, head circumference, and prenatal exposure to acrylamide from maternal diet: the European prospective mother-child study (NewGeneris).

artículo científico publicado en 2012

Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases ⬇️

artículo científico publicado en 2017

Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling

scientific article published on 24 May 2018

Bulky dna adducts in cord blood, maternal fruit-and-vegetable consumption, and birth weight in a European mother-child study (NewGeneris).

artículo científico publicado en 2013

Butylated hydroxyanisole, butylated hydroxytoluene and tert.-butylhydroquinone are not mutagenic in the Salmonella/microsome assay using new tester strains

artículo científico publicado en 1988

CYP1A2 and NAT2 genotype/phenotype relations and urinary excretion of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a human dietary intervention study

artículo científico publicado en 2004

Can transcriptomics provide insight into the chemopreventive mechanisms of complex mixtures of phytochemicals in humans?

artículo científico publicado en 2014

Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks

artículo científico publicado en 2013

Characterization of the peripheral blood transcriptome in a repeated measures design using a panel of healthy individuals

artículo científico publicado en 2013

Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs

artículo científico publicado en 2006

Cigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring

artículo científico publicado en 2012

Circulating Serum MicroRNAs as Potential Diagnostic Biomarkers of Posttraumatic Stress Disorder: A Pilot Study

scientific article published on 22 November 2019

Classification of Hepatotoxicants Using HepG2 Cells: A Proof of Principle Study

artículo científico publicado en 2014

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

artículo científico publicado en 2008

Comparing in vitro human liver models to in vivo human liver using RNA-Seq

artículo científico publicado en 2020

Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

artículo científico publicado en 2010

Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach

scientific article published on 08 September 2006

Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data

artículo científico publicado en 2012

Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver

artículo científico publicado en 2012

Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data

scientific article published on 30 August 2018

Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling

artículo científico publicado en 2005

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures ⬇️

artículo científico publicado el 28 de diciembre de 2010

Cytogenetic effects in children and mothers exposed to air pollution assessed by the frequency of micronuclei and fluorescence in situ hybridization (FISH): a family pilot study in the Czech Republic

artículo científico

DNA methylation and exposure to ambient air pollution in two prospective cohorts.

artículo científico

DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia

scientific article published on 15 February 2019

DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds

artículo científico publicado en 2016

DTW4Omics: comparing patterns in biological time series

artículo científico publicado en 2013

Decreased human semen quality and organochlorine compounds in blood

artículo científico publicado en 2002

Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene

artículo científico publicado en 2011

Differences in HPRT mutant frequency among middle-aged Flemish women in association with area of residence and blood lead levels

artículo científico publicado en 2004

Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents.

artículo científico publicado en 2005

Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs

artículo científico publicado en 2010

Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test ⬇️

artículo científico publicado el 30 de diciembre de 2010

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time

artículo científico publicado en 2009

Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling

artículo científico publicado en 2004

Discriminative protection against hydroxyl and superoxide anion radicals by quercetin in human leucocytes in vitro

artículo científico publicado en 2007

Distinct genotype-dependent differences in transcriptome responses in humans exposed to environmental carcinogens

artículo científico publicado en 2015

Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?

artículo científico publicado en 2000

Dose and Time Dependencies in Stress Pathway Responses during Chemical Exposure: Novel Insights from Gene Regulatory Networks

artículo científico publicado en 2017

Drug-induced gene expression profile changes in relation to intestinal toxicity: State-of-the-art and new approaches

scientific article published on 27 June 2019

Dynamic Interplay between the Transcriptome and Methylome in Response to Oxidative and Alkylating Stress.

artículo científico publicado en 2016

ELIXIR and Toxicology: a community in development

ELIXIR and Toxicology: a community in development

artículo científico publicado en 2023

Effect of ascorbic acid and green tea on endogenous formation of N-nitrosodimethylamine and N-nitrosopiperidine in humans.

artículo científico publicado en 1999

Effects of polyunsaturated fatty acids on prostaglandin synthesis and cyclooxygenase-mediated DNA adduct formation by heterocyclic aromatic amines in human adenocarcinoma colon cells

artículo científico publicado en 2004

Electron spin resonance spectroscopy of oxygen radicals generated by synthetic fecapentaene-12 and reduction of fecapentaene mutagenicity to Salmonella typhimurium by hydroxyl radical scavenging

artículo científico publicado el 1 de julio de 1992

Elimination of heparin interference during microarray processing of fresh and biobank-archived blood samples.

artículo científico

Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury

article

Environmental exposure to N-nitroso compounds and their precursors

artículo científico publicado en 1996

Environmental genotoxins in children and adults: Introduction and overview

artículo científico publicado en 2006

Environmental, dietary, maternal, and fetal predictors of bulky DNA adducts in cord blood: a European mother-child study (NewGeneris) ⬇️

artículo científico publicado en 2015

Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis

artículo científico publicado en 2014

Epigenome-wide association study of adiposity and future risk of obesity-related diseases

article by Gianluca Campanella et al published 1 May 2018 in International Journal of Obesity

Erratum: "Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)".

artículo científico publicado en 2016

Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes

artículo científico publicado en 2015

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures ⬇️

artículo científico publicado el 8 de octubre de 2010

Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity

artículo científico publicado en 2014

Evaluation of exposure reducing measures on parameters of genetic risk in a population occupationally exposed to coal fly ash.

artículo científico publicado en 1993

Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

artículo científico publicado en 2017

Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity

artículo científico publicado en 2016

Exposure-route-dependent DNA adduct formation by polycyclic aromatic hydrocarbons.

artículo científico publicado en 2000

Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells.

artículo científico publicado en 2015

Fecapentaene excretion and fecal mutagenicity in relation to nutrient intake and fecal parameters in humans on omnivorous and vegetarian diets

artículo científico publicado en 1992

Fetal exposure to dietary carcinogens and risk of childhood cancer: what the NewGeneris project tells us.

artículo científico publicado en 2015

Formation of nitrosamines during consumption of nitrate- and amine-rich foods, and the influence of the use of mouthwashes.

artículo científico publicado en 1998

Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells

artículo científico publicado en 2014

From the exposome to mechanistic understanding of chemical-induced adverse effects

artículo científico publicado en 2016

FuSe: A tool to move RNA-Seq analyses from chromosomal/gene loci to functional grouping of mRNA transcripts

artículo científico publicado en 2020

GSTM1 and GSTT1 polymorphism influences protection against induced oxidative DNA damage by quercetin and ascorbic acid in human lymphocytes in vitro.

artículo científico publicado en 2007

Gender-specific transcriptomic response to environmental exposure in Flemish adults

artículo científico publicado en 2013

Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

artículo científico publicado en 2021

Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro.

artículo científico publicado en 2002

Genes associated with Parkinson's disease respond to increasing polychlorinated biphenyl levels in the blood of healthy females

article

Genomic analysis suggests higher susceptibility of children to air pollution

artículo científico publicado en 2008

Genotoxicity of coal fly ash, assessed in vitro in Salmonella typhimurium and human lymphocytes, and in vivo in an occupationally exposed population

artículo científico publicado en 1989

Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero

artículo científico publicado en 2012

Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells

artículo científico publicado en 2009

Helicobacter pylori does not mediate the formation of carcinogenic N-nitrosamines

artículo científico publicado en 2002

High-throughput data integration of RNA-miRNA-circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicity

artículo científico publicado en 2015

Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity

artículo científico publicado en 2011

Human health risk assessment in relation to environmental pollution of two artificial freshwater lakes in The Netherlands

artículo científico publicado en 1999

Human health risk assessment: A case study involving heavy metal soil contamination after the flooding of the river Meuse during the winter of 1993-1994.

artículo científico publicado en 1999

Human respiratory disease: environmental carcinogens and lung cancer risk.

artículo científico publicado en 1993

Identification and quantitative distribution of eight analogues of naturally occurring fecapentaenes in human feces by high-performance liquid chromatography

artículo científico publicado en 1991

Identification of Sex-Specific Transcriptome Responses to Polychlorinated Biphenyls (PCBs)

artículo científico publicado en 2019

Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics

artículo científico publicado en 2017

In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism.

artículo científico publicado en 2004

In vitro investigations into the interaction of beta-carotene with DNA: evidence for the role of carbon-centered free radicals.

artículo científico publicado en 2004

Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain

artículo científico publicado en 2015

Indoor radon exposure and cytogenetic damage

artículo científico publicado en 1992

Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes

artículo científico publicado en 2018

Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro

artículo científico publicado en 2015

Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

artículo científico publicado en 2011

Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis.

artículo científico publicado en 2016

Integrative cross-omics analysis in primary mouse hepatocytes unravels mechanisms of cyclosporin A-induced hepatotoxicity

artículo científico publicado en 2014

Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction

artículo científico publicado en 2017

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective

artículo científico publicado en 2015

Interaction between cadmium and aromatic DNA adducts in hprt mutagenesis during foetal development

artículo científico publicado en 2005

Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes

artículo científico publicado en 2015

Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices.

artículo científico publicado en 2014

Interindividual variations in DNA adduct levels assessed by analysis of multiple genetic polymorphisms in smokers.

artículo científico publicado en 2006

Intragastric volatile N-nitrosamines, nitrite, pH, and Helicobacter pylori during long-term treatment with omeprazole

artículo científico publicado en 2001

Maternal and gestational factors and micronucleus frequencies in umbilical blood: the NewGeneris Rhea cohort in Crete

artículo científico publicado en 2011

Maternal diet during pregnancy and micronuclei frequency in peripheral blood T lymphocytes in mothers and newborns (Rhea cohort, Crete).

artículo científico publicado en 2016

Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake.

artículo científico publicado en 2009

Modulation of DNA and protein adducts in smokers by genetic polymorphisms in GSTM1,GSTT1, NAT1 and NAT2.

artículo científico publicado en 2001

Modulation of nucleotide excision repair in human lymphocytes by genetic and dietary factors

artículo científico publicado en 2009

Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis

artículo científico

Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop

artículo científico publicado en 2017

Multiplex genotyping as a biomarker for susceptibility to carcinogenic exposure in the FLEHS biomonitoring study

artículo científico publicado en 2008

N-nitroso compound exposure-associated transcriptomic profiles are indicative of an increased risk for colorectal cancer

scientific article published on 12 June 2011

Negative ion fast atom bombardment and collision-induced dissociation mass spectrometry of the 2-, 3-, 4- and 6-deoxy derivatives from methyl beta-D-galactopyranoside and related compounds.

artículo científico publicado en 1994

Network integration and modelling of dynamic drug responses at multi-omics levels

scientific article published on 15 October 2020

Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation

artículo científico publicado en 2004

New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis

artículo científico publicado en 2016

New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids

artículo científico publicado en 2021

NewGeneris: a European study on maternal diet during pregnancy and child health

scientific article published on 01 January 2009

Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort

artículo científico publicado en 2017

Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines

artículo científico publicado en 1996

Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes

artículo científico publicado en 2017

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking ⬇️

artículo científico publicado en 2016

Outdoor air pollution exposures and micronuclei frequencies in lymphocytes from pregnant women and newborns in Crete, Greece (Rhea cohort).

artículo científico publicado en 2015

Oxidative Stress Mechanisms Do Not Discriminate between Genotoxic and Nongenotoxic Liver Carcinogens.

artículo científico publicado en 2015

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

artículo científico publicado en 2008

Pattern recognition methods to relate time profiles of gene expression with phenotypic data: a comparative study

artículo científico publicado en 2015

Performance in omics analyses of blood samples in long-term storage: opportunities for the exploitation of existing biobanks in environmental health research

artículo científico publicado en 2013

Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity

artículo científico publicado en 2012

Peroxidation of linoleic, arachidonic and oleic acid in relation to the induction of oxidative DNA damage and cytogenetic effects.

artículo científico publicado en 1994

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

artículo científico publicado en 2018

Persistent transcriptional responses show the involvement of feed-forward control in a repeated dose toxicity study

artículo científico publicado en 2016

Phosphorylation of eIF2α promotes cell survival in response to benzo[a]pyrene exposure

artículo científico publicado en 2018

Possible relevance of pigeons as an indicator species for monitoring air pollution

artículo científico publicado en 1997

Potential protein markers for nutritional health effects on colorectal cancer in the mouse as revealed by proteomics analysis

artículo científico publicado en 2006

Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans

artículo científico publicado en 2009

Pre-diagnostic blood immune markers, incidence and progression of B-cell lymphoma and multiple myeloma: Univariate and functionally informed multivariate analyses.

artículo científico publicado en 2018

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

artículo científico publicado en 2011

Protection by quercetin and quercetin-rich fruit juice against induction of oxidative DNA damage and formation of BPDE-DNA adducts in human lymphocytes

artículo científico publicado en 2005

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells ⬇️

artículo científico publicado el 16 de diciembre de 2010

Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity

artículo científico

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene

artículo científico publicado en 2012

Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells

artículo científico publicado en 2010

Rationale for Environmental Hygiene towards global protection of fetuses and young children from adverse lifestyle factors.

artículo científico publicado en 2018

Red meat intake-induced increases in fecal water genotoxicity correlate with pro-carcinogenic gene expression changes in the human colon.

artículo científico publicado en 2011

Relationship between radical generation by urban ambient particulate matter and pulmonary function of school children.

artículo científico publicado en 2006

Response to cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity.

artículo científico publicado en 2015

Risk assessment of endogenous formation of carcinogenic N-nitroso compounds in response to intake of NO-aspirin

artículo científico publicado en 2004

Role of oxidative DNA damage in the mechanism of fecapentaene-12 genotoxicity.

artículo científico publicado en 1994

Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach

artículo científico publicado en 2013

Sex-Specific Associations between Particulate Matter Exposure and Gene Expression in Independent Discovery and Validation Cohorts of Middle-Aged Men and Women.

artículo científico publicado en 2016

Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies

artículo científico publicado en 2018

Simultaneous genotyping of nine polymorphisms in xenobiotic-metabolizing enzymes by multiplex PCR amplification and single base extension

artículo científico publicado en 2004

Stimulation of renal adrenergic mechanisms as a model for the development of hypertension

Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

artículo científico publicado en 2014

The CYP1A2-164A-->C polymorphism (CYP1A2*1F) is associated with the risk for colorectal adenomas in humans

artículo científico publicado en 2005

The MicroRNA-based Liquid Biopsy Improves Early Assessment of Lethal Acetaminophen Poisoning: A Case Report

scientific article published on 22 February 2020

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

artículo científico publicado en 2008

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

artículo científico publicado en 2014

The effect of dietary estimates calculated using food frequency questionnaires on micronuclei formation in European pregnant women: a NewGeneris study

artículo científico publicado en 2014

The exposome concept in a human nutrigenomics study: evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signatures

artículo científico publicado en 2015

The presence of the cag pathogenicity island is associated with increased superoxide anion radical scavenging activity by Helicobacter pylori.

artículo científico publicado en 2005

The use of 4-aminobiphenyl hemoglobin adducts and aromatic DNA adducts in lymphocytes of smokers as biomarkers of exposure.

artículo científico publicado en 1998

Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets

artículo científico publicado en 2010

Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells

artículo científico

Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells.

artículo científico publicado en 2011

Toward interoperable bioscience data

artículo científico publicado en 2012

ToxDB: pathway-level interpretation of drug-treatment data

artículo científico publicado en 2016

Toxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns

artículo científico publicado en 2012

Toxicogenomics directory of chemically exposed human hepatocytes

artículo científico publicado en 2014

Toxicogenomics in genetic toxicology and hazard determination--concluding remarks

artículo científico publicado en 2005

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Transcriptome analysis in peripheral blood of humans exposed to environmental carcinogens: a promising new biomarker in environmental health studies.

artículo científico publicado en 2008

Transcriptome responses in blood reveal distinct biological pathways associated with arsenic exposure through drinking water in rural settings of Punjab, Pakistan

scientific article published on 18 December 2019

Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure

artículo científico

Transcriptomic and metabolomic data integration

artículo científico publicado en 2015

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

artículo científico publicado en 2013

Translational Proteomics Analysis of Anthracycline-Induced Cardiotoxicity From Cardiac Microtissues to Human Heart Biopsies

artículo científico publicado en 2021

Translational regulation is a key determinant of the cellular response to benzo[a]pyrene

artículo científico publicado en 2018

Use of crayfish in biomonitoring studies of environmental pollution of the river Meuse

artículo científico publicado en 1999

Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.

artículo científico

Vegetables Affect the Expression of Genes Involved in Anticarcinogenic Processes in the Colonic Mucosa of C57Bl/6 Female Mice

article

Vitamin D insufficient levels during pregnancy and micronuclei frequency in peripheral blood T lymphocytes mothers and newborns (Rhea cohort, Crete).

artículo científico publicado en 2016

Volatile N-nitrosamine formation after intake of nitrate at the ADI level in combination with an amine-rich diet

artículo científico publicado en 1998

Volatile N-nitrosamines in gastric juice of patients with various conditions of the gastrointestinal tract determined by gas chromatography-mass spectrometry and related to intragastric pH and nitrate and nitrite levels

artículo científico publicado en 1998

Whole-genome gene expression modifications associated with nitrosamine exposure and micronucleus frequency in human blood cells.

artículo científico publicado en 2011

Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26-27 June 2013, Research Triangle Park, NC, USA.

artículo científico publicado en 2014

diXa: a data infrastructure for chemical safety assessment

artículo científico publicado en 2014

microRNA expression profiles and personal monitoring of exposure to particulate matter

scientific article published on 18 March 2020

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