Lista de obras - Pekka Kohonen - Dominio Público Uruguay

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

artículo científico publicado en 2010

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

artículo científico publicado en 2017

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

artículo científico publicado en 2017

Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

artículo científico publicado en 2014

Androgen regulation of micro-RNAs in prostate cancer

artículo científico publicado en 2010

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

artículo científico publicado en 2011

Avian Helios and evolution of the Ikaros family

artículo científico publicado en 2004

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

artículo científico publicado en 2014

Can an InChI for Nano Address the Need for a Simplified Representation of Complex Nanomaterials across Experimental and Nanoinformatics Studies?

artículo científico publicado en 2020

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

artículo científico publicado en 2014

Chapter 11. Computational Modelling of Biological Responses to Engineered Nanomaterials

Chicken B-cell-activating factor: regulator of B-cell survival in the bursa of fabricius

artículo científico publicado en 2004

Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP.

artículo científico publicado en 2010

Development of early PCLP1-expressing haematopoietic cells within the avian dorsal aorta.

artículo científico publicado en 2005

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

artículo científico publicado en 2010

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

artículo científico publicado en 2017

ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.

artículo científico publicado en 2012

Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

scholarly article published in Breast Cancer Research and Treatment

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

artículo científico publicado en 2013

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets

artículo científico publicado en 2011

Genotoxic and epigenetic effects of silver nanoparticles

scholarly article by Hanna L. Karlsson et al published June 2012 in Toxicology Letters

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

artículo científico publicado en 2011

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

artículo científico publicado en 2016

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

artículo científico publicado en 2009

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

artículo científico publicado en 2012

Identification of a novel cytokine-like transcript differentially expressed in avian gammadelta T cells

artículo científico publicado en 2004

Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact

artículo científico publicado en 2011

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

artículo científico publicado en 2010

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

artículo científico publicado en 2013

Insight into lymphoid development by gene expression profiling of avian B cells.

artículo científico publicado en 2003

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

scholarly article by Noffisat O. Oki et al published February 2019 in Toxicology in Vitro

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer

artículo científico publicado en 2011

Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

artículo científico publicado en 2010

Loss of Pax5 promotes plasma cell differentiation

artículo científico publicado en 2006

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

artículo científico publicado en 2011

Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors

artículo científico publicado en 2018

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

artículo científico publicado en 2015

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases

artículo científico publicado en 2012

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

artículo científico publicado en 2014

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

artículo científico publicado en 2009

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

artículo científico

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

artículo científico publicado en 2017

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

artículo científico publicado en 2015

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

artículo científico publicado en 2011

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

scientific article published on 28 November 2011

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

artículo científico publicado en 2013

The eNanoMapper database for nanomaterial safety information

artículo científico publicado en 2015

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design ⬇️

artículo científico publicado en 2014

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

scientific article published on 08 January 2020

Towards FAIR nanosafety data

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome.

artículo científico publicado en 2018

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

artículo científico publicado en 2020

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

scientific article published on 08 May 2020

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

scientific article published on 08 April 2020

miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen

artículo científico publicado en 2014

toxFlow: a Web-Based Application for Read-Across Toxicity Prediction using Omics and Physicochemical Data.

artículo científico publicado en 2017

Lista de obras de Pekka Kohonen

A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

Androgen regulation of micro-RNAs in prostate cancer

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

Avian Helios and evolution of the Ikaros family

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

Can an InChI for Nano Address the Need for a Simplified Representation of Complex Nanomaterials across Experimental and Nanoinformatics Studies?

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

Chapter 11. Computational Modelling of Biological Responses to Engineered Nanomaterials

Chicken B-cell-activating factor: regulator of B-cell survival in the bursa of fabricius

Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP.

Development of early PCLP1-expressing haematopoietic cells within the avian dorsal aorta.

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.

Erratum to: Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets

Genotoxic and epigenetic effects of silver nanoparticles

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

Identification of a novel cytokine-like transcript differentially expressed in avian gammadelta T cells

Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

Insight into lymphoid development by gene expression profiling of avian B cells.

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer

Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

Loss of Pax5 promotes plasma cell differentiation

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

The eNanoMapper database for nanomaterial safety information

The eNanoMapper database for nanomaterial safety information

The first eNanoMapper prototype: A substance database to support safe-by-design ⬇️

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

Towards FAIR nanosafety data

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome.

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen

toxFlow: a Web-Based Application for Read-Across Toxicity Prediction using Omics and Physicochemical Data.