Lista de obras - Ueli Suter - Dominio Público Uruguay

A new missense GDAP1 mutation disturbing targeting to the mitochondrial membrane causes a severe form of AR-CMT2C disease

artículo científico publicado en 2011

AFM combines functional and morphological analysis of peripheral myelinated and demyelinated nerve fibers.

artículo científico publicado en 2007

An animal model for Charcot-Marie-Tooth disease type 4B1.

artículo científico publicado en 2005

Analysis of neural crest-derived clones reveals novel aspects of facial development

artículo científico publicado en 2016

Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells.

artículo científico publicado en 2009

Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.

artículo científico publicado en 2014

Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

artículo científico publicado en 2004

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

artículo científico publicado en 2006

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.

artículo científico publicado en 2008

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

artículo científico publicado en 2019

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

artículo científico publicado en 2010

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

scientific article published on 01 October 2006

Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation.

artículo científico publicado en 2006

Cell-intrinsic and cell-extrinsic cues regulating lineage decisions in multipotent neural crest-derived progenitor cells.

artículo científico publicado en 2002

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.

artículo científico publicado en 2013

Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells

artículo científico publicado en 2005

Conduction block in PMP22 deficiency.

artículo científico publicado en 2010

De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination.

artículo científico publicado en 2018

Dicer in Schwann cells is required for myelination and axonal integrity

scientific journal article

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain

scientific journal article

Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point mutation

artículo científico publicado en 2005

Distinct elements of the peripheral myelin protein 22 (PMP22) promoter regulate expression in Schwann cells and sensory neurons

artículo científico publicado en 2003

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

scientific journal article

Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

artículo científico publicado en 2017

Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination

artículo científico publicado en 2012

E-cadherin Is Required for the Correct Formation of Autotypic Adherens Junctions of the Outer Mesaxon but Not for the Integrity of Myelinated Fibers of Peripheral Nerves

artículo científico publicado en 2002

E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles

artículo científico publicado en 2003

Early neuronal and glial fate restriction of embryonic neural stem cells

scientific article published on 01 March 2008

Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells.

artículo científico publicado en 2004

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

artículo científico publicado en 2010

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

artículo científico publicado en 2006

Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

artículo científico publicado en 2007

Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom

artículo científico publicado en 2004

Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle

artículo científico publicado en 2008

FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.

artículo científico publicado en 2005

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance.

artículo científico publicado en 2009

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

artículo científico publicado en 2005

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system

artículo científico publicado en 2010

Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.

artículo científico publicado en 2011

Glial origin of mesenchymal stem cells in a tooth model system

artículo científico publicado en 2014

Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

artículo científico publicado en 2016

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

artículo científico publicado en 2012

HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.

scientific article published on April 2014

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

artículo científico publicado en 2011

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

artículo científico publicado en 2015

How Histone Deacetylases Control Myelination ⬇️

artículo científico publicado el 23 de agosto de 2011

Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves.

artículo científico publicado en 2002

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

artículo científico publicado en 2009

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

article

Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

artículo científico publicado en 2005

Injury-activated glial cells promote wound healing of the adult skin in mice

artículo científico publicado en 2018

Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells

artículo científico publicado en 2004

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

scientific journal article

Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia

artículo científico publicado en 2006

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.

artículo científico publicado en 2005

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

artículo científico publicado en 2004

LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: implications for Charcot-Marie-Tooth disease

artículo científico publicado en 2012

Lineage-specific requirements of beta-catenin in neural crest development

artículo científico publicado en 2002

Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1.

artículo científico publicado en 2002

MRI signature in a novel mouse model of genetically induced adult oligodendrocyte cell death.

artículo científico publicado en 2011

Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module ⬇️

artículo científico publicado el 6 de octubre de 2003

Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.

artículo científico publicado en 2002

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

artículo científico publicado en 2012

Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy

scientific article published on 04 March 2020

Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush

scientific journal article

Molecular Biology of Axon–Glia Interactions in the Peripheral Nervous System1

scholarly article by Verdon Taylor published in January 1997

Molecular cell biology of Charcot-Marie-Tooth disease.

artículo científico publicado en 2002

Molecular mechanisms regulating myelination in the peripheral nervous system

artículo científico

Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2

scientific article published on 12 September 2007

Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

scientific journal article

Murine numb regulates granule cell maturation in the cerebellum

artículo científico publicado en 2004

Muscle-specific function of the centronuclear myopathy and Charcot-Marie-Tooth neuropathy-associated dynamin 2 is required for proper lipid metabolism, mitochondria, muscle fibers, neuromuscular junctions and peripheral nerves

artículo científico publicado en 2013

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

artículo científico publicado en 2012

Myelination and mTOR.

artículo científico publicado en 2017

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling

artículo científico publicado en 2005

Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

artículo científico publicado en 2006

Neural membrane protein 35/Lifeguard is localized at postsynaptic sites and in dendrites

artículo científico publicado en 2002

Neuropathy in a human without the PMP22 gene.

artículo científico publicado en 2011

Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury

artículo científico publicado en 2002

Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

artículo científico publicado en 2004

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain

artículo científico publicado en 2002

Notch1 control of oligodendrocyte differentiation in the spinal cord

scientific journal article

Notch1 is required for neuronal and glial differentiation in the cerebellum.

artículo científico publicado en 2002

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway.

artículo científico publicado en 2016

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

scientific journal article

Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease

artículo científico publicado en 2006

Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

artículo científico publicado en 2007

Postnatal Schwann cell proliferation but not myelination is strictly and uniquely dependent on cyclin-dependent kinase 4 (cdk4).

artículo científico publicado en 2007

Profilin 1 is required for peripheral nervous system myelination.

artículo científico publicado en 2014

Proliferation of Schwann cells and regulation of cyclin D1 expression in an animal model of Charcot-Marie-Tooth disease type 1A

artículo científico publicado en 2002

Quantifying the early stages of remyelination following cuprizone-induced demyelination.

artículo científico publicado en 2003

Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system

scientific article published on 14 June 2019

Regulation of neural progenitor proliferation and survival by beta1 integrins

artículo científico publicado en 2005

SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling

artículo científico publicado en 2010

SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system

artículo científico publicado en 2009

Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin.

artículo científico publicado en 2009

Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease).

artículo científico publicado en 2006

Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function

scientific article published on 16 January 2019

Small Rho GTPases are key regulators of peripheral nerve biology in health and disease.

artículo científico publicado en 2008

Sox10 haploinsufficiency affects maintenance of progenitor cells in a mouse model of Hirschsprung disease

artículo científico publicado en 2002

Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve

artículo científico publicado en 2011

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest.

artículo científico publicado en 2012

Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.

artículo científico publicado en 2009

Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis.

artículo científico publicado en 2013

Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells

artículo científico publicado en 2003

Targeting and function of the mitochondrial fission factor GDAP1 are dependent on its tail-anchor

artículo científico publicado en 2009

Temporal control of neural crest lineage generation by Wnt/β-catenin signaling

artículo científico publicado en 2012

The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling

artículo científico publicado en 2011

The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

artículo científico publicado en 2014

The Lin28/let-7 axis is critical for myelination in the peripheral nervous system

artículo científico publicado en 2015

The early life of a Schwann cell

artículo científico publicado en 2002

The function of RhoGTPases in axon ensheathment and myelination

artículo científico publicado en 2008

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells

artículo científico publicado en 2018

The protooncogene Ski controls Schwann cell proliferation and myelination

artículo científico publicado en 2004

The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system

artículo científico publicado en 2004

The role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cells

scientific journal article

The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool.

artículo científico publicado en 2011

Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A).

artículo científico publicado en 2003

Understanding Schwann cell-neurone interactions: the key to Charcot-Marie-Tooth disease?

artículo científico publicado en 2002

Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord

artículo científico publicado en 2006

Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

artículo científico publicado en 2016

mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.

artículo científico publicado en 2014

mTORC1 is transiently reactivated in injured nerves to promote c-Jun elevation and Schwann cell dedifferentiation.

artículo científico publicado en 2018

Lista de obras de Ueli Suter

A new missense GDAP1 mutation disturbing targeting to the mitochondrial membrane causes a severe form of AR-CMT2C disease

AFM combines functional and morphological analysis of peripheral myelinated and demyelinated nerve fibers.

An animal model for Charcot-Marie-Tooth disease type 4B1.

Analysis of neural crest-derived clones reveals novel aspects of facial development

Antigens expressed by myelinating glia cells induce peripheral cross-tolerance of endogenous CD8+ T cells.

Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.

Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance

Beta1-integrin signaling mediates premyelinating oligodendrocyte survival but is not required for CNS myelination and remyelination.

Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion.

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

Cdc42 and Rac1 Signaling Are Both Required for and Act Synergistically in the Correct Formation of Myelin Sheaths in the CNS

Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation.

Cell-intrinsic and cell-extrinsic cues regulating lineage decisions in multipotent neural crest-derived progenitor cells.

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission.

Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells

Conduction block in PMP22 deficiency.

De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination.

Dicer in Schwann cells is required for myelination and axonal integrity

Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain

Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point mutation

Distinct elements of the peripheral myelin protein 22 (PMP22) promoter regulate expression in Schwann cells and sensory neurons

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination

E-cadherin Is Required for the Correct Formation of Autotypic Adherens Junctions of the Outer Mesaxon but Not for the Integrity of Myelinated Fibers of Peripheral Nerves

E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles

Early neuronal and glial fate restriction of embryonic neural stem cells

Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells.

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development

Expression analysis of the N-Myc downstream-regulated gene 1 indicates that myelinating Schwann cells are the primary disease target in hereditary motor and sensory neuropathy-Lom

Expression and localization of Ski determine cell type-specific TGFbeta signaling effects on the cell cycle

FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35.

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance.

Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease

Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system

Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.

Glial origin of mesenchymal stem cells in a tooth model system

Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins

How Histone Deacetylases Control Myelination ⬇️

Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves.

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

Injury-activated glial cells promote wound healing of the adult skin in mice

Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia

Jagged1 signals in the postnatal subventricular zone are required for neural stem cell self-renewal.

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: implications for Charcot-Marie-Tooth disease

Lineage-specific requirements of beta-catenin in neural crest development

Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1.

MRI signature in a novel mouse model of genetically induced adult oligodendrocyte cell death.

Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module ⬇️

Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy

Mice lacking protease nexin-1 show delayed structural and functional recovery after sciatic nerve crush

Molecular Biology of Axon–Glia Interactions in the Peripheral Nervous System1

Molecular cell biology of Charcot-Marie-Tooth disease.

Molecular mechanisms regulating myelination in the peripheral nervous system

Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2

Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

Murine numb regulates granule cell maturation in the cerebellum

Muscle-specific function of the centronuclear myopathy and Charcot-Marie-Tooth neuropathy-associated dynamin 2 is required for proper lipid metabolism, mitochondria, muscle fibers, neuromuscular junctions and peripheral nerves

Myelin is dependent on the Charcot-Marie-Tooth Type 4H disease culprit protein FRABIN/FGD4 in Schwann cells

Myelination and mTOR.

Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling

Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin

Neural membrane protein 35/Lifeguard is localized at postsynaptic sites and in dendrites

Neuropathy in a human without the PMP22 gene.

Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury