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Lista de obras de Johanna Kuusisto

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.

artículo científico publicado en 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

artículo científico publicado en 2018

A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study

artículo científico publicado en 2017

A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus

artículo científico publicado en 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell

artículo científico publicado en 2014

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

artículo científico publicado en 2011

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A novel mutation, Arg71Thr, in the ?-sarcoglycan gene is associated with dilated cardiomyopathy ⬇️

artículo científico publicado el 15 de octubre de 2003

A novel mutation, Ser143Pro, in the lamin A/C gene is common in finnish patients with familial dilated cardiomyopathy

artículo científico publicado en 2004

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose

artículo científico publicado en 2009

Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes

artículo científico publicado en 2012

Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss

artículo científico publicado en 2013

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association analysis of peroxisome proliferator-activated receptor gamma polymorphisms and late onset Alzheimer's disease in the Finnish population

artículo científico publicado en 2006

Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

artículo científico publicado en 2009

Association of Common Genetic Variation in The FOXO1 Gene with β-Cell Dysfunction, Impaired Glucose Tolerance, And Type 2 Diabetes

artículo científico publicado en 2009

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes

artículo científico publicado en 2009

Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes.

artículo científico publicado en 2013

Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.

scientific article published on 04 April 2013

Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism – The Finnish Diabetes Prevention Study

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of multiple lipoprotein and apolipoprotein measures with worsening of glycemia and incident type 2 diabetes in 6607 non-diabetic Finnish men.

artículo científico publicado en 2015

Atherosclerosis and cardiovascular risk reduction with PPAR agonists

artículo científico publicado en 2007

Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 Finnish men

artículo científico publicado en 2015

CMR derived left ventricular septal convexity in carriers of the hypertrophic cardiomyopathy-causing MYBPC3-Q1061X mutation

Cardiac adrenergic activity is associated with left ventricular hypertrophy in genetically homogeneous subjects with hypertrophic cardiomyopathy

artículo científico publicado en 2003

Cardiac sympathetic activity is associated with inflammation and neurohumoral activation in patients with idiopathic dilated cardiomyopathy

artículo científico publicado en 2009

Cardiomyopathy associated with the Ala143Thr variant of the α-galactosidase A gene

scientific article published on 16 January 2020

Cardiovascular magnetic resonance of mitral valve length in hypertrophic cardiomyopathy

artículo científico publicado en 2016

Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men

scientific article published on 17 February 2009

Cine MR imaging of myocardial contractile impairment in patients with hypertrophic cardiomyopathy attributable to Asp175Asn mutation in the alpha-tropomyosin gene

artículo científico publicado en 2005

Circulating RNAs as predictive markers for the progression of type 2 diabetes

Circulating TNF-Alpha and IL-6 Concentrations and TNF-Alpha -308 G > A Polymorphism in Children with Premature Adrenarche

artículo científico publicado en 2010

Clinical disease presentation and ECG characteristics of LMNA mutation carriers

artículo científico publicado en 2017

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects

artículo científico publicado en 2009

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

artículo científico publicado en 2008

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

artículo científico publicado en 2017

Concordance and heritability of multiple sclerosis in Finland: study on a nationwide series of twins

scholarly article by H. Kuusisto et al published 25 August 2008 in European Journal of Neurology

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Current perspectives in hypertrophic cardiomyopathy with the focus on patients in the Finnish population: a review

artículo científico publicado en 2016

Decreased plasma C-reactive protein levels in 4 allele carriers

Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers

artículo científico publicado en 2017

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Description of A/C gene mutation related dilated cardiomyopathy with gadolinium- enhanced magnetic resonance imaging

artículo científico publicado en 2011

Desmosterol in human nonalcoholic steatohepatitis

artículo científico publicado en 2013

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Diabetes Secondary to Treatment with Statins

artículo científico publicado en 2017

Dietary fat in relation to erythrocyte fatty acid composition in men

artículo científico publicado en 2013

Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial

artículo científico publicado en 2015

Differential Associations of Inflammatory Markers With Insulin Sensitivity and Secretion: The Prospective METSIM Study

artículo científico publicado en 2017

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Disentangling the genetics of lean mass

article

Early familial dilated cardiomyopathy: identification with determination of disease state parameter from cine MR image data

artículo científico publicado en 2008

Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.

artículo científico publicado en 2011

Epigenome-wide association in adipose tissue from the METSIM cohort.

artículo científico publicado en 2018

Epigenome-wide association in adipose tissue from the METSIM cohort.

artículo científico publicado en 2018

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles

artículo científico publicado en 2011

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

artículo científico publicado en 2012

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

artículo científico publicado en 2012

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Fasting and OGTT-derived measures of insulin resistance as compared with the euglycemic-hyperinsulinemic clamp in nondiabetic Finnish offspring of type 2 diabetic individuals

artículo científico publicado en 2014

Fatty acid metabolism is altered in non-alcoholic steatohepatitis independent of obesity

artículo científico publicado en 2016

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Finnish Diabetes Risk Score Is Associated with Impaired Insulin Secretion and Insulin Sensitivity, Drug-Treated Hypertension and Cardiovascular Disease: A Follow-Up Study of the METSIM Cohort

artículo científico publicado en 2016

First-pass MR imaging in the assessment of perfusion impairment in patients with hypertrophic cardiomyopathy and the Asp175Asn mutation of the alpha-tropomyosin gene

artículo científico publicado en 2003

Functional Variant in the GCKR Gene Affects Lactate Levels Differentially in the Fasting State and During Hyperglycemia

artículo científico publicado en 2018

Galanin preproprotein is associated with elevated plasma triglycerides

artículo científico publicado en 2008

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits

artículo científico publicado en 2017

Genetic basis and outcome in a nationwide study of Finnish patients with hypertrophic cardiomyopathy

Genetic evidence of assortative mating in humans

article

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

artículo científico publicado en 2009

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

artículo científico publicado en 2015

Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

artículo científico publicado en 2013

Genetic risk scores in the prediction of plasma glucose, impaired insulin secretion, insulin resistance and incident type 2 diabetes in the METSIM study

artículo científico publicado en 2017

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetics of hypertrophic cardiomyopathy in eastern Finland: few founder mutations with benign or intermediary phenotypes

artículo científico publicado en 2004

Genetics of hypertrophic cardiomyopathy: what is the next step?

artículo científico publicado en 2020

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

artículo científico publicado en 2016

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

artículo científico publicado en 2022

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

artículo científico publicado en 2011

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study identifies eight loci associated with blood pressure

artículo científico publicado en 2009

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

artículo científico publicado en 2011

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

artículo científico publicado en 2015

Glycated hemoglobin levels are mostly dependent on nonglycemic parameters in 9398 Finnish men without diabetes

artículo científico publicado en 2015

Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men

artículo científico publicado en 2013

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

artículo científico publicado en 2012

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

artículo científico publicado en 2018

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics

artículo científico publicado en 2009

Identification of undiagnosed type 2 diabetic individuals by the finnish diabetes risk score and biochemical and genetic markers: a population-based study of 7232 Finnish men.

artículo científico publicado en 2010

Idiopathic dilated cardiomyopathy and chronic atrial fibrillation

artículo científico publicado en 2013

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

artículo científico publicado en 2013

Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort

artículo científico publicado en 2015

Increased ventilatory response to exercise in symptomatic and asymptomatic LMNA mutation carriers: a follow-up study

artículo científico publicado en 2015

Increased visceral adipose tissue as a potential risk factor in patients with embolic stroke of undetermined source (ESUS)

artículo científico publicado en 2015

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

artículo científico publicado en 2017

Insulin resistance and hyperglycaemia in cardiovascular disease development

artículo científico

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study

artículo científico publicado en 2010

Integrative approaches for large-scale transcriptome-wide association studies

artículo científico publicado en 2016

Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.

artículo científico publicado en 2015

Lamin A/C mutation affecting primarily the right side of the heart

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Late gadolinium enhanced cardiovascular magnetic resonance of lamin A/C gene mutation related dilated cardiomyopathy

artículo científico publicado en 2011

Left ventricular mechanical dispersion is associated with nonsustained ventricular tachycardia in hypertrophic cardiomyopathy

artículo científico publicado en 2016

Link between GIP and osteopontin in adipose tissue and insulin resistance

artículo científico publicado en 2013

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

artículo científico publicado en 2015

Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy

artículo científico publicado en 2012

Markers of tissue-specific insulin resistance predict the worsening of hyperglycemia, incident type 2 diabetes and cardiovascular disease

artículo científico publicado en 2014

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Metabolic syndrome and incident end-stage peripheral vascular disease: a 14-year follow-up study in elderly Finns

artículo científico publicado en 2007

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

artículo científico publicado en 2019

Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol

artículo científico publicado en 2015

Mutations in the cardiac myosin-binding protein C gene are the predominant cause of familial hypertrophic cardiomyopathy in eastern Finland

article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

artículo científico publicado en 2012

No variants in the cardiac actin gene in Finnish patients with dilated or hypertrophic cardiomyopathy

scientific article published on 01 June 2002

Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men

artículo científico publicado en 2013

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

artículo científico publicado en 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

artículo científico publicado en 2011

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease

artículo científico publicado en 2017

Plasma fatty acids as predictors of glycaemia and type 2 diabetes

artículo científico publicado en 2015

Pleiotropic effects of GIP on islet function involve osteopontin

artículo científico publicado en 2011

Predicting glycated hemoglobin levels in the non-diabetic general population: Development and validation of the DIRECT-DETECT prediction model - a DIRECT study

artículo científico publicado en 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

artículo científico publicado en 2018

Regulation of alternative splicing in human obesity loci

artículo científico publicado en 2016

Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

artículo científico publicado en 2017

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

artículo científico publicado en 2011

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans.

artículo científico publicado en 2011

Serum lipidomics meets cardiac magnetic resonance imaging: profiling of subjects at risk of dilated cardiomyopathy

artículo científico publicado en 2011

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Short Adult Stature Predicts Impaired β-Cell Function, Insulin Resistance, Glycemia, and Type 2 Diabetes in Finnish Men.

artículo científico publicado en 2016

Significance of plasma levels of N-terminal Pro-B-type natriuretic peptide on left ventricular remodeling in non-obstructive hypertrophic cardiomyopathy attributable to the Asp175Asn mutation in the alpha-tropomyosin gene

artículo científico publicado en 2008

Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells

artículo científico publicado en 2015

Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans

artículo científico publicado en 2007

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

artículo científico publicado en 2008

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

artículo científico publicado en 2018

Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans

article

The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels

artículo científico publicado en 2009

The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies

artículo científico publicado en 2010

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases

artículo científico publicado en 2017

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy

artículo científico publicado en 2015

The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain

artículo científico publicado en 2004

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge

artículo científico publicado en 2011

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology

artículo científico publicado en 2017

The metabolic syndrome predicts cardiovascular mortality: a 13-year follow-up study in elderly non-diabetic Finns

artículo científico publicado en 2007

The metabolic syndrome predicts incident congestive heart failure: a 20-year follow-up study of elderly Finns

artículo científico publicado en 2009

The metabolic syndrome predicts incident stroke: a 14-year follow-up study in elderly people in Finland

artículo científico publicado en 2008

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus

artículo científico publicado en 2017

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

artículo científico publicado en 2013

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Two founder mutations in the alpha-tropomyosin and the cardiac myosin-binding protein C genes are common causes of hypertrophic cardiomyopathy in the Finnish population

artículo científico publicado en 2012

Two novel mutations in the beta-myosin heavy chain gene associated with dilated cardiomyopathy

artículo científico publicado en 2004

Underlying genetic models of inheritance in established type 2 diabetes associations

artículo científico publicado en 2009

Update on type 2 diabetes as a cardiovascular disease risk equivalent

artículo científico publicado en 2013

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

artículo científico publicado en 2008

Variants in MTNR1B influence fasting glucose levels

artículo científico publicado en 2008

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion

article

WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels

artículo científico publicado en 2008

[What new about hypertrophic cardiomyopathy?]

artículo científico publicado en 2003

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