Filtros de búsqueda

Lista de obras de Stella Trompet

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A critical appraisal of pharmacogenetic inference

artículo científico publicado en 2017

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention

artículo científico publicado en 2011

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

artículo científico publicado en 2013

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

artículo científico publicado en 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

artículo científico publicado en 2013

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application?

artículo científico publicado en 2011

ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment

artículo científico publicado en 2014

Activation of hemostasis and decline in cognitive function in older people

artículo científico publicado en 2009

An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

artículo científico publicado en 2020

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

artículo científico publicado en 2014

Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study

artículo científico publicado en 2009

Assessment of causality between serum gamma-glutamyltransferase and type 2 diabetes mellitus using publicly available data: a Mendelian randomization study

artículo científico publicado en 2016

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study

article published in 2019

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

artículo científico publicado en 2019

Association of High-Density Lipoprotein Cholesterol With Cognitive Function: Findings From the PROspective Study of Pravastatin in the Elderly at Risk

artículo científico publicado en 2020

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

artículo científico publicado en 2018

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of cardiovascular structure and function with cerebrovascular changes and cognitive function in older patients with end-stage renal disease

scientific article published on 07 January 2020

Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts

scientific article published on 02 December 2020

Association of common genetic variants with brain microbleeds: A Genome-wide Association Study

scientific article published on 10 September 2020

Association of complement receptor 1 gene polymorphisms with cognitive function

artículo científico publicado en 2017

Association of fasting triglyceride concentration and postprandial triglyceride response with the carotid intima-media thickness in the middle aged: The Netherlands Epidemiology of Obesity study

artículo científico publicado en 2017

Association of metabolic syndrome and electrocardiographic markers of subclinical cardiovascular disease

artículo científico publicado en 2017

Association of the fat mass and obesity-associated gene risk allele, rs9939609A, and reward-related brain structures

artículo científico publicado en 2015

Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults

scientific article published on 10 September 2020

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Blood Pressure Lowering Medication, Visit-to-Visit Blood Pressure Variability, and Cognitive Function in Old Age.

artículo científico publicado en 2015

Body fat distribution, in particular visceral fat, is associated with cardiometabolic risk factors in obese women

artículo científico publicado en 2017

Borderline Q-waves in individuals without overt cardiovascular disease: Relations with adiposity, subclinical atherosclerosis and vascular stiffness

artículo científico publicado en 2018

C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study

artículo científico publicado en 2011

CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease

artículo científico publicado en 2018

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

artículo científico publicado en 2017

Cerebral microbleeds are predictive of mortality in the elderly

artículo científico publicado en 2011

Cerebral small vessel disease genomics and its implications across the lifespan

artículo científico publicado en 2020

Circulating Interleukin-10 and Risk of Cardiovascular Events

scholarly article by Paul Welsh et al published October 2011 in Arteriosclerosis, Thrombosis, and Vascular Biology

Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study

artículo científico publicado en 2013

Clinical determinants of low handgrip strength and its decline in the oldest old: the Leiden 85-plus Study

artículo científico publicado en 2020

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

artículo científico publicado en 2020

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common variants in Mendelian kidney disease genes and their association with renal function

artículo científico publicado en 2013

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

artículo científico publicado en 2017

Complement receptor 1 gene polymorphisms are associated with cardiovascular risk.

artículo científico publicado en 2016

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Design and rationale of a routine clinical care pathway and prospective cohort study in older patients needing intensive treatment

artículo científico publicado en 2021

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

artículo científico publicado en 2016

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Does low to moderate alcohol intake protect against cognitive decline in older people?

artículo científico publicado en 2008

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

artículo científico publicado en 2015

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

artículo científico publicado en 2013

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

artículo científico publicado en 2019

Electrocardiographic Detection of Left Ventricular Hypertrophy; Adding Body Mass Index and Spatial QRS-T Angle: A Cross-Sectional Study

scientific article published on 16 October 2019

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity

artículo científico publicado en 2016

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Evidence-based medicine in older patients: how can we do better?

artículo científico

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality

artículo científico publicado en 2011

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

artículo científico publicado en 2015

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

artículo científico publicado en 2018

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

artículo científico publicado en 2018

GWAS for executive function and processing speed suggests involvement of the CADM2 gene.

artículo científico publicado en 2015

Gene-gene Interaction Analyses for Atrial Fibrillation

artículo científico publicado en 2016

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

artículo científico publicado en 2017

Genetic Risk Prediction of Atrial Fibrillation

artículo científico publicado en 2016

Genetic Variation in the Interleukin-10 Gene Promoter and Risk of Coronary and Cerebrovascular Events: The PROSPER Study

article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in Human Cardiovascular Disease

artículo científico publicado en 2019

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

artículo científico publicado en 2015

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

artículo científico publicado en 2016

Genetic predictors of fibrin D-dimer levels in healthy adults

artículo científico publicado en 2011

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population

artículo científico publicado en 2008

Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly

artículo científico publicado en 2011

Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies

article

Genetic variation in galectin-3 gene associates with cognitive function at old age.

artículo científico publicado en 2012

Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study

artículo científico publicado en 2008

Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study

artículo científico publicado en 2017

Genetics: Genetic risk scores--new promises for drug evaluation

artículo científico publicado en 2015

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

artículo científico publicado en 2015

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

artículo científico publicado en 2016

Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group

artículo científico publicado en 2019

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in Hepatic Lipase (LIPC)

artículo científico publicado en 2020

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

artículo científico publicado en 2016

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and functional follow-up reveals new loci for kidney function

artículo científico publicado en 2012

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

artículo científico publicado en 2014

Genome-wide association studies identify genetic loci for low von Willebrand factor levels

artículo científico publicado en 2015

Genome-wide association studies identify genetic loci for low von Willebrand factor levels

artículo científico publicado en 2016

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

artículo científico publicado en 2014

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

artículo científico publicado en 2018

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

artículo científico publicado en 2012

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

artículo científico publicado en 2017

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry

scientific article published on 06 December 2019

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy

artículo científico publicado en 2012

Health care expenditure in the last five years of life is driven by morbidity, not age: A national study of spending trajectories in Danish decedents over age 65

artículo científico publicado en 2020

Hematopoietic capacity and exceptional survival: the Leiden Longevity Study

artículo científico publicado en 2008

High Innate Production Capacity of Proinflammatory Cytokines Increases Risk for Death from Cancer: Results of the PROSPER Study

artículo científico publicado en 2009

High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants

artículo científico publicado en 2017

High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk

artículo científico publicado en 2016

Higher Visit-to-Visit Low-Density Lipoprotein Cholesterol Variability Is Associated With Lower Cognitive Performance, Lower Cerebral Blood Flow, and Greater White Matter Hyperintensity Load in Older Subjects

artículo científico publicado en 2016

Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction

artículo científico publicado en 2011

IL7R gene expression network associates with human healthy ageing

artículo científico publicado en 2015

In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study.

artículo científico publicado en 2014

Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease ⬇️

artículo científico publicado el 30 de marzo de 2011

Increasing HDL-C levels with medication: current perspectives

artículo científico publicado en 2017

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

artículo científico publicado en 2014

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

artículo científico publicado en 2012

Interplay of Circulating Leptin and Obesity in Cognition and Cerebral Volumes in Older Adults

artículo científico publicado en 2020

Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis

artículo científico publicado en 2019

Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

artículo científico publicado en 2015

KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly

artículo científico publicado en 2012

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

artículo científico publicado en 2016

LDL cholesterol still a problem in old age? A Mendelian randomization study

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group.

artículo científico publicado en 2016

Lessons from Mendelian randomization studies on liver biomarkers: response to Abbasi

scientific article published on 01 October 2017

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

artículo científico publicado en 2014

Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)

artículo científico publicado en 2013

Low thyroid function is not associated with an accelerated deterioration in renal function.

artículo científico publicado en 2018

Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study

artículo científico publicado en 2008

Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of reste

artículo científico publicado el 1 de enero de 2010

Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.

artículo científico publicado en 2017

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

artículo científico publicado en 2019

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

artículo científico publicado en 2016

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

artículo científico publicado en 2020

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

artículo científico publicado en 2018

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2018

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

artículo científico publicado en 2016

Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

artículo científico publicado en 2015

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

artículo científico publicado en 2013

N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk

artículo científico publicado en 2014

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis

artículo científico publicado en 2016

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

artículo científico publicado en 2014

Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data

artículo científico publicado en 2013

Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies

artículo científico publicado en 2015

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

artículo científico publicado en 2016

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

artículo científico publicado en 2014

Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997.

artículo científico publicado en 2017

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites

artículo científico publicado en 2017

PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population

artículo científico publicado en 2013

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

Pathway analysis using genome-wide association study data for coronary restenosis--a potential role for the PARVB gene

artículo científico publicado en 2013

Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients

artículo científico publicado en 2016

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

artículo científico publicado en 2014

Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives

artículo científico

Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology

artículo científico publicado en 2017

Plasma apolipoprotein-B is an important risk factor for cardiovascular disease, and its assessment should be routine clinical practice

artículo científico publicado en 2018

Pravastatin and cognitive function in the elderly. Results of the PROSPER study

artículo científico publicado en 2009

Prevalence of Carriers of Intermediate and Pathological Polyglutamine Disease-Associated Alleles Among Large Population-Based Cohorts

scientific article published on 01 June 2019

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype

artículo científico publicado en 2013

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials

artículo científico publicado en 2018

Relation of Overall and Abdominal Adiposity With Electrocardiogram Parameters of Subclinical Cardiovascular Disease in Individuals Aged 45 to 65 Years (from the Netherlands Epidemiology of Obesity Study).

artículo científico publicado en 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

artículo científico publicado en 2017

Renal Impairment, Cardiovascular Disease, and the Short-Term Efficacy and Safety of PCSK9 Targeted by Inclisiran

artículo científico publicado en 2020

Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer's disease

artículo científico publicado en 2018

Repeat length variations in polyglutamine disease-associated genes affect body mass index

scientific article published on 17 August 2018

Repeat variations in polyglutamine disease-associated genes and cognitive function in old age

scientific article published on 09 August 2019

Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses

artículo científico publicado en 2011

Response to Ciuculete et al.

artículo científico publicado en 2017

Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

artículo científico publicado en 2016

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Serum calcium and cognitive function in old age.

artículo científico publicado en 2007

Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin

scientific article published on 01 August 2018

Spatial QRS-T Angle and Cognitive Decline in Older Subjects

artículo científico publicado en 2019

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

scientific article published on 05 December 2019

Statins and blood pressure

artículo científico publicado en 2008

Statins reduce the risk of cancer-related mortality in cancer-diagnosed patients. A true phenomenon?

artículo científico publicado en 2013

Statins work around the world

artículo científico publicado en 2013

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

artículo científico publicado en 2018

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

artículo científico publicado en 2016

Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk

scholarly article by David Nanchen et al published March 2012 in The Journal of Clinical Endocrinology and Metabolism

Subclinical thyroid dysfunction and cognitive decline in old age

artículo científico publicado en 2013

Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies

artículo científico publicado en 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

artículo científico publicado en 2019

Survival Bias in Mendelian Randomization Studies: A Threat to Causal Inference

artículo científico publicado en 2019

Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study

artículo científico publicado en 2012

TAC-TIC use of tacrolimus-based regimens in lupus nephritis

scientific article published on 29 December 2016

THE BIDIRECTIONAL RELATIONSHIP BETWEEN VISION AND COGNITION: A SYSTEMATIC REVIEW AND META-ANALYSIS

artículo científico publicado en 2020

TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies

artículo científico publicado en 2010

Ten-year mortality risk of patients undergoing elective PCI: long-term follow-up of the GENetic Determinants of Restenosis (GENDER) study : No increased mortality risk by restenosis, only by coronary artery disease itself

artículo científico publicado en 2013

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis

artículo científico publicado en 2020

The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study

scientific article published on 04 June 2020

The controversies of statin therapy: weighing the evidence

artículo científico publicado en 2012

The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients

artículo científico publicado en 2020

The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies

artículo científico publicado en 2020

The role of inflammation in the association between overall and visceral adiposity and subclinical atherosclerosis

artículo científico publicado en 2019

Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study

artículo científico publicado en 2017

Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts

artículo científico publicado en 2015

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study

artículo científico publicado en 2006

Using genetic variation for establishing causality of cardiovascular risk factors: overcoming confounding and reverse causality

artículo científico publicado en 2014

Value of platelet pharmacogenetics in common clinical practice of patients with ST-segment elevation myocardial infarction

artículo científico publicado en 2012

Variation in the CBP gene involved in epigenetic control associates with cognitive function

artículo científico publicado en 2010

Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults

artículo científico publicado en 2020

Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco)genetics

artículo científico publicado en 2018

White Matter Lesion Progression: Genome-Wide Search for Genetic Influences

artículo científico publicado en 2015

White blood cell count and C-reactive protein are independent predictors of mortality in the oldest old.

artículo científico publicado en 2010

Will the interplay between genetic markers for risk factors for a disease and the disease itself bring genetics closer to clinical practice? Great expectations

artículo científico publicado en 2011

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda