Lista de obras - Ivelin Georgiev - Dominio Público Uruguay

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2015

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

artículo científico publicado en 2018

A critical analysis of computational protein design with sparse residue interaction graphs

artículo científico publicado en 2017

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

artículo científico publicado en 2012

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

artículo científico publicado en 2012

Activation and lysis of human CD4 cells latently infected with HIV-1

artículo científico publicado en 2015

Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons

artículo científico publicado en 2017

Algorithm for backrub motions in protein design

artículo científico publicado en 2008

Antibacterial photosensitization through activation of coproporphyrinogen oxidase.

artículo científico publicado en 2017

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

artículo científico publicado en 2014

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

artículo científico publicado en 2017

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

scientific article published on 01 June 2019

BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design

artículo científico publicado en 2016

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

artículo científico publicado en 2015

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

artículo científico publicado en 2019

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

artículo científico publicado en 2014

Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection

artículo científico publicado en 2011

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

artículo científico publicado en 2017

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

artículo científico publicado en 2014

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

article

Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

artículo científico publicado en 2018

Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial

artículo científico publicado en 2015

Computational prediction of N-linked glycosylation incorporating structural properties and patterns ⬇️

artículo científico publicado el 10 de julio de 2012

Computational structure-based redesign of enzyme activity

artículo científico publicado en 2009

Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

article

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

artículo científico publicado en 2020

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

artículo científico publicado en 2011

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

Dead-end elimination with backbone flexibility

artículo científico publicado en 2007

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

artículo científico publicado en 2013

Design of epitope-specific probes for sera analysis and antibody isolation

artículo científico publicado en 2012

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

artículo científico publicado en 2014

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

artículo científico publicado en 2012

Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.

artículo científico publicado en 2013

Eliminating antibody polyreactivity through addition of N-linked glycosylation

artículo científico publicado en 2015

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

artículo científico publicado en 2014

Enhancing the Solubility of HIV-1-neutralizing Antibody 10E8.

artículo científico publicado en 2014

Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection

scientific article published on 25 March 2020

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

artículo científico publicado en 2012

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

artículo científico publicado en 2018

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

artículo científico publicado en 2011

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

artículo científico publicado en 2016

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

article

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

artículo científico publicado en 2013

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

scientific article published on 28 November 2019

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

artículo científico publicado en 2020

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

artículo científico publicado en 2016

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

artículo científico publicado en 2014

Improved Pruning algorithms and Divide-and-Conquer strategies for Dead-End Elimination, with application to protein design

artículo científico publicado en 2006

Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

artículo científico publicado en 2012

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

artículo científico publicado en 2016

Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity.

artículo científico publicado en 2014

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Kernel-based logistic regression model for protein sequence without vectorialization

artículo científico publicado en 2014

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

scientific article published on 01 February 2020

Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.

artículo científico publicado en 2011

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

artículo científico publicado en 2017

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

artículo científico publicado en 2016

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

artículo científico publicado en 2015

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

artículo científico publicado en 2017

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

artículo científico publicado en 2019

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

artículo científico publicado en 2018

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

artículo científico publicado en 2013

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

artículo científico publicado en 2016

NEP: web server for epitope prediction based on antibody neutralization of viral strains with diverse sequences

artículo científico publicado en 2014

NFPws: a web server for delineating broadly neutralizing antibody specificities from serum HIV-1 neutralization data

artículo científico publicado en 2019

OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design

artículo científico publicado en 2017

OSPREY: protein design with ensembles, flexibility, and provable algorithms

artículo científico publicado en 2013

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

artículo científico publicado en 2016

Partial germline reversions can increase VRC07 potency and breadth.

artículo científico publicado en 2012

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

artículo científico publicado en 2020

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

artículo científico publicado en 2017

Predicting resistance mutations using protein design algorithms

artículo científico publicado en 2010

Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features

article

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

artículo científico publicado en 2015

Protein design algorithms predict viable resistance to an experimental antifolate

artículo científico publicado en 2014

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

RV144 HIV-1 vaccination impacts post-infection antibody responses

artículo científico publicado en 2020

Redesigning the PheA domain of gramicidin synthetase leads to a new understanding of the enzyme's mechanism and selectivity

artículo científico publicado en 2006

Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains

artículo científico publicado en 2013

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

artículo científico publicado en 2015

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

artículo científico publicado en 2017

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

artículo científico publicado en 2013

Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine Antigens

scientific article published on 24 January 2020

Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle

artículo científico publicado en 2012

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

artículo científico publicado en 2010

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

artículo científico publicado en 2014

Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

artículo científico publicado en 2012

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

artículo científico publicado en 2012

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

artículo científico publicado en 2017

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

artículo científico publicado en 2016

Structure-guided modification and optimization of antibody VRC07.

artículo científico publicado en 2012

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody

artículo científico publicado en 2018

Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection

artículo científico publicado en 2015

The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection

artículo científico publicado en 2015

The minimized dead-end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles

artículo científico publicado en 2008

The role of local backrub motions in evolved and designed mutations

artículo científico publicado en 2012

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

artículo científico publicado en 2016

Transforming epitope-specific gp120 monomer-based probes into immunogens with N-linked glycan masking

artículo científico publicado en 2012

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

artículo científico publicado en 2018

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

artículo científico publicado en 2014

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

artículo científico publicado en 2017

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site

artículo científico publicado en 2015

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

artículo científico publicado en 2016

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

artículo científico publicado en 2017

Lista de obras de Ivelin Georgiev

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.

A critical analysis of computational protein design with sparse residue interaction graphs

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.

A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies

Activation and lysis of human CD4 cells latently infected with HIV-1

Adipose Tissue is Enriched for Activated and Late-Differentiated CD8+ T Cells and Shows Distinct CD8+ Receptor Usage, Compared With Blood in HIV-Infected Persons

Algorithm for backrub motions in protein design

Antibacterial photosensitization through activation of coproporphyrinogen oxidase.

Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design

Bispecific Antibodies Targeting Different Epitopes on the HIV-1 Envelope Exhibit Broad and Potent Neutralization.

Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial

Computational prediction of N-linked glycosylation incorporating structural properties and patterns ⬇️

Computational structure-based redesign of enzyme activity

Correction for Acharya et al., Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Dead-end elimination with backbone flexibility

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

Design of epitope-specific probes for sera analysis and antibody isolation

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape

Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.

Eliminating antibody polyreactivity through addition of N-linked glycosylation

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

Enhancing the Solubility of HIV-1-neutralizing Antibody 10E8.

Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

Improved Pruning algorithms and Divide-and-Conquer strategies for Dead-End Elimination, with application to protein design

Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity.

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Kernel-based logistic regression model for protein sequence without vectorialization

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Longitudinal Antibody Responses in People Who Inject Drugs Infected With Similar Human Immunodeficiency Virus Strains

Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy.

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding

NEP: web server for epitope prediction based on antibody neutralization of viral strains with diverse sequences

NFPws: a web server for delineating broadly neutralizing antibody specificities from serum HIV-1 neutralization data

OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design

OSPREY: protein design with ensembles, flexibility, and provable algorithms

Optimization of a Clade A Env Outer Domain for Enhanced Binding to Germlines of Diverse VRC01 Class Antibodies

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

Partial germline reversions can increase VRC07 potency and breadth.

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

Predicting resistance mutations using protein design algorithms

Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features