Lista de obras - Marc Graille - Dominio Público Uruguay

A B-cell superantigen that targets B-1 lymphocytes.

artículo científico publicado en 2000

A highly conserved region essential for NMD in the Upf2 N-terminal domain

artículo científico publicado en 2014

A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III.

artículo científico publicado en 2004

A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast

artículo científico publicado en 2017

Activation mode of the eukaryotic m2G10 tRNA methyltransferase Trm11 by its partner protein Trm112

artículo científico publicado en 2016

Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes

artículo científico publicado en 2005

An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro

artículo científico publicado en 2007

Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.

artículo científico publicado en 2006

Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins

artículo científico publicado en 2001

Crystal Structure of PAV1-137: A Protein from the Virus PAV1 That InfectsPyrococcus abyssi

artículo científico publicado en 2013

Crystal structure and functional characterization of yeast YLR011wp, an enzyme with NAD(P)H-FMN and ferric iron reductase activities

artículo científico publicado en 2004

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity

artículo científico publicado en 2000

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

artículo científico publicado en 2008

Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archaeal and bacterial enzymes

artículo científico publicado en 2005

Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family

artículo científico publicado en 2004

Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase

artículo científico publicado en 2004

Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold

artículo científico publicado en 2005

Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae

artículo científico publicado en 2004

Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response

scientific article published on 30 September 2005

Crystal structure of the effector AvrLm4-7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins.

artículo científico publicado en 2015

Crystal structure of the yeast His6 enzyme suggests a reaction mechanism

artículo científico publicado en 2006

Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate

artículo científico publicado en 2003

Crystal structure of yeast YER010Cp, a knotable member of the RraA protein family

artículo científico publicado en 2005

Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family

artículo científico publicado en 2005

Crystal structure of yeast allantoicase reveals a repeated jelly roll motif

artículo científico publicado en 2004

Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins (αRep) based on thermostable HEAT-like repeats

artículo científico publicado en 2010

Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways

artículo científico publicado en 2010

Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface

artículo científico publicado en 2002

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes

scientific article published on 01 September 2018

Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering

artículo científico publicado en 2005

Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa

artículo científico publicado en 2012

HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories

artículo científico publicado en 2005

High-throughput crystal-optimization strategies in the South Paris Yeast Structural Genomics Project: one size fits all?

artículo científico publicado en 2005

Identification of the Rps28 binding motif from yeast Edc3 involved in the autoregulatory feedback loop controlling RPS28B mRNA decay

artículo científico publicado en 2013

Immunoglobulin-binding domains: Protein L from Peptostreptococcus magnus

artículo científico publicado en 2003

Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure

artículo científico publicado en 2015

Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein

artículo científico publicado en 2011

Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein

artículo científico publicado en 2015

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX

artículo científico publicado en 2012

Methylation of class I translation termination factors: structural and functional aspects.

artículo científico

Molecular basis for bacterial class I release factor methylation by PrmC.

artículo científico publicado en 2005

Observation and characterization of the interaction between a single immunoglobulin binding domain of protein L and two equivalents of human kappa light chains

artículo científico publicado en 2003

Protein L mutants for the crystallization of antibody fragments

artículo científico publicado en 2002

Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

artículo científico publicado en 2013

Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project

artículo científico publicado en 2011

Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe

artículo científico publicado en 2011

Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi

artículo científico publicado en 2014

Structural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription ⬇️

artículo científico publicado en 2010

Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes

artículo científico publicado en 2014

Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein

artículo científico publicado en 2004

Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae

artículo científico publicado en 2014

Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity

artículo científico publicado en 2004

Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m7GDP and its Edc3 activator

artículo científico publicado en 2016

Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex

artículo científico publicado en 2008

Structure of yeast Dom34: a protein related to translation termination factor Erf1 and involved in No-Go decay

artículo científico publicado en 2008

Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase

artículo científico publicado en 2006

Structure-function analysis of Knr4/Smi1, a newly member of intrinsically disordered proteins family, indispensable in the absence of a functional PKC1-SLT2 pathway in Saccharomyces cerevisiae

artículo científico publicado en 2008

Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways

artículo científico publicado en 2006

Surveillance pathways rescuing eukaryotic ribosomes lost in translation

The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

scientific article published on 29 April 2020

The C-Terminal Domain from S. cerevisiae Pat1 Displays Two Conserved Regions Involved in Decapping Factor Recruitment

artículo científico publicado en 2014

The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis

artículo científico publicado en 2019

The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase.

artículo científico publicado en 2006

The Paris-Sud yeast structural genomics pilot-project: from structure to function

artículo científico publicado en 2004

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

scientific article published on 01 September 2019

The structure of an archaeal homodimeric ligase which has RNA circularization activity

artículo científico publicado en 2008

The structure of the NasR transcription antiterminator reveals a one-component system with a NIT nitrate receptor coupled to an ANTAR RNA-binding effector

artículo científico publicado en 2012

The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya

artículo científico publicado en 2009

The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases

artículo científico publicado en 2008

The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast

artículo científico publicado en 2006

Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.

artículo científico publicado en 2012

Trm112, a Protein Activator of Methyltransferases Modifying Actors of the Eukaryotic Translational Apparatus

artículo científico publicado en 2017

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein

artículo científico publicado en 2011

Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding

artículo científico publicado en 2010

mRNA decapping: finding the right structures

artículo científico publicado en 2018

Lista de obras de Marc Graille

A B-cell superantigen that targets B-1 lymphocytes.

A highly conserved region essential for NMD in the Upf2 N-terminal domain

A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III.

A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast

Activation mode of the eukaryotic m2G10 tRNA methyltransferase Trm11 by its partner protein Trm112

Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes

An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro

Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.

Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins

Crystal Structure of PAV1-137: A Protein from the Virus PAV1 That InfectsPyrococcus abyssi

Crystal structure and functional characterization of yeast YLR011wp, an enzyme with NAD(P)H-FMN and ferric iron reductase activities

Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archaeal and bacterial enzymes

Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family

Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase

Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold

Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae

Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response

Crystal structure of the effector AvrLm4-7 of Leptosphaeria maculans reveals insights into its translocation into plant cells and recognition by resistance proteins.

Crystal structure of the yeast His6 enzyme suggests a reaction mechanism

Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate

Crystal structure of yeast YER010Cp, a knotable member of the RraA protein family

Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family

Crystal structure of yeast allantoicase reveals a repeated jelly roll motif

Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins (αRep) based on thermostable HEAT-like repeats

Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways

Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes

Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering

Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa

HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories

High-throughput crystal-optimization strategies in the South Paris Yeast Structural Genomics Project: one size fits all?

Identification of the Rps28 binding motif from yeast Edc3 involved in the autoregulatory feedback loop controlling RPS28B mRNA decay

Immunoglobulin-binding domains: Protein L from Peptostreptococcus magnus

Insights into molecular plasticity in protein complexes from Trm9-Trm112 tRNA modifying enzyme crystal structure

Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein

Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX

Methylation of class I translation termination factors: structural and functional aspects.

Molecular basis for bacterial class I release factor methylation by PrmC.

Observation and characterization of the interaction between a single immunoglobulin binding domain of protein L and two equivalents of human kappa light chains

Protein L mutants for the crystallization of antibody fragments

Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)

Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project

Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe

Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi

Structural and functional insights into Saccharomyces cerevisiae Tpa1, a putative prolylhydroxylase influencing translation termination and transcription ⬇️

Structural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes

Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein

Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae

Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity

Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m7GDP and its Edc3 activator

Structure of the archaeal Kae1/Bud32 fusion protein MJ1130: a model for the eukaryotic EKC/KEOPS subcomplex

Structure of yeast Dom34: a protein related to translation termination factor Erf1 and involved in No-Go decay

Structure-based functional annotation: yeast ymr099c codes for a D-hexose-6-phosphate mutarotase

Structure-function analysis of Knr4/Smi1, a newly member of intrinsically disordered proteins family, indispensable in the absence of a functional PKC1-SLT2 pathway in Saccharomyces cerevisiae

Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways

Surveillance pathways rescuing eukaryotic ribosomes lost in translation

The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

The C-Terminal Domain from S. cerevisiae Pat1 Displays Two Conserved Regions Involved in Decapping Factor Recruitment

The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis

The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase.

The Paris-Sud yeast structural genomics pilot-project: from structure to function

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112

The structure of an archaeal homodimeric ligase which has RNA circularization activity

The structure of the NasR transcription antiterminator reveals a one-component system with a NIT nitrate receptor coupled to an ANTAR RNA-binding effector

The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya

The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases

The zinc finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast

Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.

Trm112, a Protein Activator of Methyltransferases Modifying Actors of the Eukaryotic Translational Apparatus

X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia coli Colicin M Immunity Protein

Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding

mRNA decapping: finding the right structures