Lista de obras - Stefano Bruno - Dominio Público Uruguay

ATP binding to human serine racemase is cooperative and modulated by glycine

artículo científico publicado en 2013

ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus

artículo científico publicado en 2012

Allosteric Effectors of Hemoglobin: Past, Present and Future

artículo científico publicado en 2011

Biochemistry of Hemoglobin

Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin

artículo científico publicado en 2012

CO Rebinding Kinetics and Molecular Dynamics Simulations Highlight Dynamic Regulation of Internal Cavities in Human Cytoglobin

artículo científico publicado en 2013

Characterization of ligand migration mechanisms inside hemoglobins from the analysis of geminate rebinding kinetics

artículo científico publicado en 2008

Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus

artículo científico publicado en 2017

Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels

artículo científico publicado en 2006

Correlation of protein functional properties in the crystal and in solution: the case study of T-state hemoglobin

artículo científico publicado en 2002

Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes

artículo científico publicado en 2002

Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana

article

Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria

artículo científico publicado en 2014

Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes

scholarly article by Luca Ronda published in January 2011

Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

scientific article published on 18 July 2018

Engineered chimeras reveal the structural basis of hexacoordination in globins: a case study of neuroglobin and myoglobin.

artículo científico publicado en 2014

Enhanced geminate ligand rebinding upon photo-dissociation of silica gel-embedded myoglobin–CO

artículo científico publicado en 2001

Erratum to: ‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)

artículo científico publicado en 2015

Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models.

artículo científico publicado en 2015

Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca

artículo científico publicado en 2012

From protein structure to function via single crystal optical spectroscopy

artículo científico publicado en 2015

Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state.

artículo científico publicado en 2003

Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides

artículo científico publicado en 2015

Functional characterization of heme proteins encapsulated in wet nanoporous silica gels.

artículo científico publicado en 2001

Functional properties of the active core of human cystathionine beta-synthase crystals.

artículo científico publicado en 2001

Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP.

artículo científico publicado en 2018

Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions

artículo científico publicado en 2010

Heterogeneous kinetics of the carbon monoxide association and dissociation reaction to nitrophorin 4 and 7 coincide with structural heterogeneity of the gate-loop

artículo científico publicado en 2012

High and low oxygen affinity conformations of T state hemoglobin

artículo científico publicado en 2001

High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model

artículo científico publicado en 2018

Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 fromArabidopsis thaliana

artículo científico publicado en 2011

Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives

scholarly article by Stefano Bruno published in August 2016

Human serine racemase is nitrosylated at multiple sites.

artículo científico publicado en 2018

Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins

artículo científico publicado en 2014

Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin

artículo científico publicado en 2010

Ligand migration in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

artículo científico publicado en 2007

Ligand migration through the internal hydrophobic cavities in human neuroglobin

artículo científico publicado en 2009

Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers.

artículo científico publicado en 2008

Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin

artículo científico publicado en 2008

Ligation tunes protein reactivity in an ancient haemoglobin: kinetic evidence for an allosteric mechanism in Methanosarcina acetivorans protoglobin

artículo científico publicado en 2012

Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes

artículo científico publicado en 2011

Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form.

artículo científico publicado en 2017

Modulation of expression and polymerization of hemoglobin Polytaur, a potential blood substitute

scholarly article by Serena Faggiano published in January 2011

Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.

artículo científico publicado en 2017

Mutational Effects at the Subunit Interfaces of Human Hemoglobin: Evidence for a Unique Sensitivity of the T Quaternary State to Changes in the Hinge Region of the α1β2 Interface†

article

New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels

scholarly article

Ormosil gels doped with engineered catechol 1,2 dioxygenases for chlorocatechol bioremediation

artículo científico publicado en 2014

Oxygen and nitric oxide rebinding kinetics in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

artículo científico publicado en 2011

Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport

article

Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state

artículo científico publicado en 2008

PEGylation promotes hemoglobin tetramer dissociation.

artículo científico publicado en 2009

Polymerization of hemoglobins in Arctic fish: Lycodes reticulatus and Gadus morhua.

artículo científico publicado en 2011

Polymerized and polyethylene glycol-conjugated hemoglobins: A globin-based calibration curve for dynamic light scattering analysis

scholarly article by Serena Faggiano published in June 2010

Protein crystal microspectrophotometry ⬇️

artículo científico publicado el 22 de diciembre de 2010

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

article

Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases

artículo científico publicado en 2016

Site-directed mutations of human hemoglobin at residue 35beta: a residue at the intersection of the alpha1beta1, alpha1beta2, and alpha1alpha2 interfaces

artículo científico publicado en 2001

Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state

artículo científico publicado en 2003

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

artículo científico publicado en 2015

Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme

artículo científico publicado en 2002

Structural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutants

artículo científico publicado en 2011

Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants

artículo científico publicado en 2011

Structural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.

artículo científico publicado en 2009

Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.

artículo científico publicado en 2015

Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin

artículo científico publicado en 2004

Targeting cystalysin, a virulence factor of treponema denticola-supported periodontitis

artículo científico publicado en 2014

Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins

artículo científico publicado en 2013

The Greenland shark Somniosus microcephalus-Hemoglobins and ligand-binding properties.

artículo científico publicado en 2017

The SoxYZ complex carries sulfur cycle intermediates on a peptide swinging arm

artículo científico publicado en 2007

The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase

artículo científico publicado en 2020

The reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is controlled by the distal HisE7 and internal hydrophobic cavities

artículo científico publicado en 2007

Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis

artículo científico publicado en 2006

Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration.

artículo científico publicado en 2008

Trapping Hemoglobin in Rigid Matrices: Fine Tuning of Oxygen Binding Properties by Modulation of Encapsulation Protocols

scholarly article by Stefano Bruno et al published January 2007 in Artificial Cells, Blood Substitutes, and Biotechnology

Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanism

artículo científico publicado en 2008

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

artículo científico publicado en 2017

X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: a multidisciplinary characterization of catechol 1,2 dioxygenase

artículo científico publicado en 2011

Zinc-Substituted Myoglobin Is a Naturally Occurring Photo-antimicrobial Agent with Potential Applications in Food Decontamination.

artículo científico publicado en 2016

‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)

artículo científico publicado en 2015

Lista de obras de Stefano Bruno

ATP binding to human serine racemase is cooperative and modulated by glycine

ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus

Allosteric Effectors of Hemoglobin: Past, Present and Future

Biochemistry of Hemoglobin

Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin

CO Rebinding Kinetics and Molecular Dynamics Simulations Highlight Dynamic Regulation of Internal Cavities in Human Cytoglobin

Characterization of ligand migration mechanisms inside hemoglobins from the analysis of geminate rebinding kinetics

Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus

Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels

Correlation of protein functional properties in the crystal and in solution: the case study of T-state hemoglobin

Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes

Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana

Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria

Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes

Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

Engineered chimeras reveal the structural basis of hexacoordination in globins: a case study of neuroglobin and myoglobin.

Enhanced geminate ligand rebinding upon photo-dissociation of silica gel-embedded myoglobin–CO

Erratum to: ‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)

Experiments on Hemoglobin in Single Crystals and Silica Gels Distinguish among Allosteric Models.

Following ligand migration pathways from picoseconds to milliseconds in type II truncated hemoglobin from Thermobifida fusca

From protein structure to function via single crystal optical spectroscopy

Functional and spectroscopic characterization of half-liganded iron-zinc hybrid hemoglobin: evidence for conformational plasticity within the T state.

Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides

Functional characterization of heme proteins encapsulated in wet nanoporous silica gels.

Functional properties of the active core of human cystathionine beta-synthase crystals.

Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP.

Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions

Heterogeneous kinetics of the carbon monoxide association and dissociation reaction to nitrophorin 4 and 7 coincide with structural heterogeneity of the gate-loop

High and low oxygen affinity conformations of T state hemoglobin

High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model

Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 fromArabidopsis thaliana

Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives

Human serine racemase is nitrosylated at multiple sites.

Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins

Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin

Ligand migration in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

Ligand migration through the internal hydrophobic cavities in human neuroglobin

Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers.

Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin

Ligation tunes protein reactivity in an ancient haemoglobin: kinetic evidence for an allosteric mechanism in Methanosarcina acetivorans protoglobin

Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes

Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form.

Modulation of expression and polymerization of hemoglobin Polytaur, a potential blood substitute

Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule.

Mutational Effects at the Subunit Interfaces of Human Hemoglobin: Evidence for a Unique Sensitivity of the T Quaternary State to Changes in the Hinge Region of the α1β2 Interface†

New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels

Ormosil gels doped with engineered catechol 1,2 dioxygenases for chlorocatechol bioremediation

Oxygen and nitric oxide rebinding kinetics in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport

Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state

PEGylation promotes hemoglobin tetramer dissociation.

Polymerization of hemoglobins in Arctic fish: Lycodes reticulatus and Gadus morhua.

Polymerized and polyethylene glycol-conjugated hemoglobins: A globin-based calibration curve for dynamic light scattering analysis

Protein crystal microspectrophotometry ⬇️

Regulation of human serine racemase activity and dynamics by halides, ATP and malonate

Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases

Site-directed mutations of human hemoglobin at residue 35beta: a residue at the intersection of the alpha1beta1, alpha1beta2, and alpha1alpha2 interfaces

Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state

Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme

Structural heterogeneity and ligand gating in ferric Methanosarcina acetivorans protoglobin mutants

Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants

Structural plasticity and functional implications of internal cavities in distal mutants of type 1 non-symbiotic hemoglobin AHb1 from Arabidopsis thaliana.

Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7.

Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin

Targeting cystalysin, a virulence factor of treponema denticola-supported periodontitis

Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins

The Greenland shark Somniosus microcephalus-Hemoglobins and ligand-binding properties.

The SoxYZ complex carries sulfur cycle intermediates on a peptide swinging arm

The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase

The reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is controlled by the distal HisE7 and internal hydrophobic cavities

Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis

Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration.

Trapping Hemoglobin in Rigid Matrices: Fine Tuning of Oxygen Binding Properties by Modulation of Encapsulation Protocols

Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanism

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: a multidisciplinary characterization of catechol 1,2 dioxygenase

Zinc-Substituted Myoglobin Is a Naturally Occurring Photo-antimicrobial Agent with Potential Applications in Food Decontamination.

‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes)