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Lista de obras de Saadi Khochbin

A bromodomain-DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT.

artículo científico publicado en 2016

A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia

artículo científico publicado en 2015

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

artículo científico publicado en 2014

A unified phylogeny-based nomenclature for histone variants

artículo científico publicado en 2012

Accumulation of histone H1(0) during early Xenopus laevis development

artículo científico publicado en 1995

Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin

artículo científico publicado en 2011

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription

artículo científico

Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein

artículo científico publicado en 2003

Antisense RNA and p53 regulation in induced murine cell differentiation

artículo científico publicado el 28 de octubre de 1992

Application of bromodeoxyuridine incorporation measurements to the determination of cell distribution within the S phase of the cell cycle

artículo científico publicado en 1988

Arsenic trioxide rewires mantle cell lymphoma response to bortezomib

artículo científico publicado en 2015

Assembly and mechanosensory function of focal adhesions: experiments and models.

artículo científico publicado en 2005

Asymmetric nuclear reprogramming in somatic cell nuclear transfer?

artículo científico publicado en 2008

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

artículo científico publicado en 2016

Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock

artículo científico publicado en 2017

Bromodomain-dependent stage-specific male genome programming by Brdt

scientific journal article

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

artículo científico publicado en 2010

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

scientific journal article

Cancer hallmarks sustained by ectopic activations of placenta/male germline genes.

artículo científico publicado en 2013

Cdyl: a new transcriptional co-repressor

artículo científico publicado en 2003

Cell cycle-related accumulation of H1(0) mRNA: induction in murine erythroleukemia cells.

artículo científico publicado en 1991

Characterization of Post-Meiotic Male Germ Cell Genome Organizational States

artículo científico publicado en 2018

Characterization of a mutated p53 exhibiting a cell cycle-related nuclear translocation.

artículo científico publicado en 1994

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein ⬇️

artículo científico publicado el 1 de diciembre de 1992

Characterization of the two H1(zero)-encoding genes from Xenopus laevis.

artículo científico publicado en 1997

Chromatin and epigenetics: dynamic organization meets regulated function.

artículo científico publicado en 2003

Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B

scientific journal article

Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor

artículo científico publicado en 2002

Combination of arsenic trioxide and Dasatinib: a new strategy to treat Philadelphia chromosome-positive acute lymphoblastic leukaemia

artículo científico publicado en 2017

Combined proteomic and in silico approaches to decipher post-meiotic male genome reprogramming in mice.

artículo científico

Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat

artículo científico publicado en 1999

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

artículo científico publicado en 2009

Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells

artículo científico publicado en 2012

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

artículo científico publicado en 2007

Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter.

artículo científico publicado en 1993

Developmentally regulated chromatin acetylation and histone H1(0) accumulation

scientific article published on 01 August 1995

Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements.

artículo científico publicado en 2005

Differential Recognition of Histone H10 by Monoclonal Antibodies during Cell Differentiation and the Arrest of Cell Proliferation ⬇️

artículo científico publicado el 9 de enero de 1998

Differential histone modifications mark mouse imprinting control regions during spermatogenesis.

artículo científico publicado en 2007

Differentiation of NUT midline carcinoma by epigenomic reprogramming

artículo científico publicado en 2011

Du nouveau dans la compréhension de la reprogrammation postméiotique du génome mâle

artículo científico publicado en 2010

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

artículo científico publicado en 2016

Early events in murine erythroleukemia cells induced to differentiate: variation of the cell cycle parameters in relation to p53 accumulation

scientific article published on 01 December 1988

Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers

artículo científico publicado en 2013

Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells

artículo científico publicado en 2008

Epigenetic perturbations and cancer: innovative therapeutic strategies against cancer ⬇️

artículo científico publicado el 1 de noviembre de 2010

Establishment of male-specific epigenetic information.

artículo científico publicado en 2005

Exogenous Expression of Human Protamine 1 (hPrm1) Remodels Fibroblast Nuclei into Spermatid-like Structures.

artículo científico publicado en 2015

Expression of serpinb6 serpins in germ and somatic cells of mouse gonads

artículo científico publicado en 2006

Flow cytofluorimetric determination of protein distribution throughout the cell cycle

artículo científico publicado en 1989

From meiosis to postmeiotic events: the secrets of histone disappearance.

artículo científico publicado en 2009

Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

scientific journal article

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1

artículo científico publicado en 2004

Genome-scale acetylation-dependent histone eviction during spermatogenesis

artículo científico publicado en 2014

Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae

artículo científico publicado en 2010

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

scientific journal article

HDAC6 a new cellular stress surveillance factor.

artículo científico publicado en 2007

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

scientific journal article

HDAC6 controls the kinetics of platelet activation

scientific article published on 06 September 2012

HDAC6-p97/VCP controlled polyubiquitin chain turnover

scientific journal article

HDAC6-ubiquitin interaction controls the duration of HSF1 activation after heat shock.

artículo científico publicado en 2014

HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses

artículo científico publicado en 2005

HMGB4, a novel member of the HMGB family, is preferentially expressed in the mouse testis and localizes to the basal pole of elongating spermatids.

artículo científico publicado en 2008

HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

artículo científico publicado en 2003

Higher concentrations of histone macroH2A in the Barr body are correlated with higher nucleosome density

scientific article published on 01 November 2000

Histone Acylation beyond Acetylation: Terra Incognita in Chromatin Biology.

artículo científico publicado en 2015

Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.

artículo científico publicado en 2017

Histone deacetylase 6 is a FoxO transcription factor-dependent effector in skeletal muscle atrophy

artículo científico publicado en 2014

Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression.

artículo científico publicado en 2005

Histone deacetylase complexes: functional entities or molecular reservoirs

artículo científico publicado en 2001

Histone variants and sensing of chromatin functional states.

artículo científico publicado en 2013

Histone variants: critical determinants in tumour heterogeneity

artículo científico publicado en 2019

Histone variants: essential actors in the male genome programing.

artículo científico publicado en 2017

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

artículo científico publicado en 2011

Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers

scientific journal article

Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers.

artículo científico publicado en 2013

Identity crisis in pulmonary arterial hypertension.

artículo científico publicado en 2018

In the Heart of a Dynamic Chromatin ⬇️

artículo científico publicado el 22 de abril de 2011

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

scientific journal article

Induced malignant genome reprogramming in somatic cells by testis-specific factors ⬇️

artículo científico publicado el 21 de abril de 2011

Induction of H1(0)-gene expression in B16 murine melanoma cells

artículo científico publicado en 1992

Induction of autophagy and autophagy-dependent apoptosis in diffuse large B-cell lymphoma by a new antimalarial artemisinin derivative, SM1044.

artículo científico publicado en 2017

Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

scientific article published on 30 July 2018

Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression

artículo científico publicado en 2000

Lessons from yeast on emerging roles of the ATAD2 protein family in gene regulation and genome organization.

artículo científico publicado en 2014

Lung squamous cell carcinomas with basaloid histology represent a specific molecular entity.

artículo científico publicado en 2014

Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark

artículo científico publicado en 2014

MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones.

artículo científico publicado en 2017

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

artículo científico publicado en 2008

Misregulation of histone acetylation in Sertoli cell-only syndrome and testicular cancer

scientific article published on 01 December 2003

Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins

artículo científico publicado en 1997

Molecular models for post-meiotic male genome reprogramming.

artículo científico publicado en 2011

Monitoring the interaction between DNA and a transcription factor (MEF2A) using fluorescence correlation spectroscopy.

artículo científico publicado en 2005

Motor-driven marginal band coiling promotes cell shape change during platelet activation.

artículo científico publicado en 2014

Mouse oocytes and early embryos express multiple histone H1 subtypes

scientific journal article

Multiple control level governing H10 mRNA and protein accumulation.

artículo científico publicado en 1991

Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition

artículo científico publicado en 2004

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.

artículo científico publicado en 2017

New hypotheses for large-scale epigenome alterations in somatic cancer cells: a role for male germ-cell-specific regulators.

artículo científico publicado en 2009

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

artículo científico publicado en 2018

PenDA, a rank-based method for personalized differential analysis: Application to lung cancer

artículo científico publicado en 2020

Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

artículo científico publicado en 2007

Persian role in flowering of Islamic science

artículo científico publicado en 2000

Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis.

artículo científico publicado en 2006

Preface to the "epigenetics and development" special issue.

artículo científico publicado en 2009

Pregnancy exposure to atmospheric pollution and meteorological conditions and placental DNA methylation

artículo científico publicado en 2018

Proteomic strategy for the identification of critical actors in reorganization of the post-meiotic male genome

scientific article published on 04 October 2011

Purification and Analysis of Male Germ Cells from Adult Mouse Testis.

artículo científico publicado en 2017

Real-time imaging of histone H4 hyperacetylation in living cells

artículo científico publicado en 2009

Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies

artículo científico publicado en 2014

Recovery of RNA from flow-sorted fixed cells

artículo científico publicado en 1990

Regulated hyperacetylation of core histones during mouse spermatogenesis: involvement of histone deacetylases

artículo científico publicado en 2000

Regulation of histone H1(0) accumulation during induced differentiation of murine erythroleukemia cells

artículo científico publicado en 1991

Regulation of protein turnover by acetyltransferases and deacetylases.

artículo científico publicado en 2007

Relationship between core histone acetylation and histone H1(0) gene activity

artículo científico publicado en 1994

Remodeling somatic nuclei via exogenous expression of protamine 1 to create spermatid-like structures for somatic nuclear transfer

artículo científico publicado en 2016

Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention.

artículo científico publicado en 2004

Site-specific introduction of an acetyl-lysine mimic into peptides and proteins by cysteine alkylation.

artículo científico publicado en 2010

Stress-induced transcription of satellite III repeats.

artículo científico publicado en 2003

Structure of p300 in complex with acyl-CoA variants.

artículo científico publicado en 2016

Sustaining cancer through addictive ectopic gene activation

artículo científico publicado en 2014

Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis

artículo científico publicado en 2010

Tat-controlled protein acetylation

artículo científico publicado en 2002

The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway

scientific journal article

The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target

artículo científico publicado en 2017

The growing landscape of tubulin acetylation: lysine 40 and many more.

artículo científico publicado en 2016

The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat

artículo científico publicado en 2001

The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling

artículo científico publicado en 2003

The mystery of histone disappearance during spermatogenesis

artículo científico publicado en 2017

The origin and utility of histone deacetylases.

artículo científico publicado en 1997

The tale of protein lysine acetylation in the cytoplasm.

artículo científico publicado en 2010

The viral control of cellular acetylation signaling.

artículo científico publicado en 2003

Tip60 acetyltransferase activity is controlled by phosphorylation

artículo científico publicado en 2003

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

artículo científico publicado en 2002

Transgenerational inheritance of chromatin states

Two catalytic domains are required for protein deacetylation.

artículo científico publicado en 2005

UV laser footprinting and protein-DNA crosslinking. Application to chromatin.

artículo científico publicado en 1999

Variation of H1(0) content throughout the cell cycle in regenerating rat liver

scientific article published on 01 April 1995

What do linker histones do in chromatin?

artículo científico publicado en 1997

When are the BET factors the most sensitive to bromodomain inhibitors?

artículo científico publicado en 2013

[Cross-fire over the nucleosome: molecular basis of post-meiotic male haploid genome compaction]

scientific article published on 30 May 2012

[Epigenetics of the sperm cell]

scientific article published on 01 September 2006

[HDAC6 orchestrates cell defense responses against cytotoxic protein aggregates]

artículo científico publicado en 2008

[Intrusion of male epigenome regulators in somatic cancer cells]

scientific article published on 01 August 2008

[Nucleosome differentiation: role of histone H2A variants]

scientific article published on 01 November 2003

[Organizing the sperm nucleus]

scientific article published on 01 September 2004

[Spermiogenesis: histone acetylation triggers male genome reprogramming].

artículo científico publicado en 2009

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