Lista de obras - Milagros Medina - Dominio Público Uruguay

A laser flash absorption spectroscopy study of Anabaena sp. PCC 7119 flavodoxin photoreduction by photosystem I particles from spinach

artículo científico publicado en 1992

Arabidopsis FNRL protein is an NADPH-dependent chloroplast oxidoreductase resembling bacterial ferredoxin-NADP+ reductases

artículo científico publicado en 2017

Binding thermodynamics of ferredoxin:NADP+ reductase: two different protein substrates and one energetics

artículo científico publicado en 2009

CW-EPR and ENDOR study of cytochrome c6 from Anabaena PCC 7119.

artículo científico publicado en 2006

Characterization of cytochrome c 6 from the cyanobacterium Anabaena PCC 7119

Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase

artículo científico publicado en 2009

Crystal Structure of the FAD-Containing Ferredoxin-NADP+Reductase from the Plant PathogenXanthomonas axonopodispv. citri

artículo científico publicado en 2013

Crystallization and preliminary X-ray diffraction studies of FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2009

Crystals of Anabaena PCC 7119 ferredoxin-NADP+ reductase

artículo científico publicado en 1991

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

artículo científico publicado en 2022

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

artículo científico

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases.

artículo científico publicado en 2018

Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface

artículo científico publicado en 2009

Electron spin echo envelope modulation studies of the semiquinone anion radical of cholesterol oxidase from Brevibacterium sterolicum

artículo científico publicado en 1997

Electron transferases

artículo científico publicado en 2014

Evolutionary divergence of chloroplast FAD synthetase proteins ⬇️

artículo científico publicado el 18 de octubre de 2010

Exact analysis of heterotropic interactions in proteins: Characterization of cooperative ligand binding by isothermal titration calorimetry

artículo científico publicado en 2006

External loops at the ferredoxin-NADP(+) reductase protein-partner binding cavity contribute to substrates allocation

artículo científico publicado en 2014

Flavin photochemistry in the analysis of electron transfer reactions: role of charged and hydrophobic residues at the carboxyl terminus of ferredoxin-NADP(+) reductase in the interaction with its substrates

artículo científico publicado en 2002

Flavoproteins and flavoenzymes with biomedical and therapeutic impact

artículo científico publicado en 2013

Histones cause aggregation and fusion of lipid vesicles containing phosphatidylinositol-4-phosphate

artículo científico publicado en 2015

Hyperfine correlation spectroscopy and electron spin echo envelope modulation spectroscopy study of the two coexisting forms of the hemeprotein cytochrome c6 from Anabaena Pcc7119.

artículo científico publicado en 2009

Identification of arginyl residues involved in the binding of ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 to its substrates

artículo científico publicado en 1992

In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

artículo científico publicado en 2020

Insights into the FMNAT Active Site of FAD Synthase: Aromaticity is Essential for Flavin Binding and Catalysis ⬇️

artículo científico publicado en 2020

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

artículo científico publicado en 2016

Key residues at the riboflavin kinase catalytic site of the bifunctional riboflavin kinase/FMN adenylyltransferase from Corynebacterium ammoniagenes

artículo científico publicado en 2013

Kinetic and chemical characterization of aldehyde oxidation by fungal aryl-alcohol oxidase

artículo científico publicado en 2010

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2017

Lysine residues on ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 involved in substrate binding

artículo científico publicado en 1992

Mechanism of coenzyme recognition and binding revealed by crystal structure analysis of ferredoxin-NADP+ reductase complexed with NADP+

artículo científico publicado en 2002

Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase.

artículo científico publicado en 2018

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

artículo científico

Oligomeric state in the crystal structure of modular FAD synthetase provides insights into its sequential catalysis in prokaryotes

artículo científico publicado en 2010

Protein dynamics promote hydride tunnelling in substrate oxidation by aryl-alcohol oxidase

artículo científico publicado en 2017

Protein motifs involved in coenzyme interaction and enzymatic efficiency in anabaena ferredoxin-NADP+ reductase

artículo científico publicado en 2009

Protein-protein interaction in electron transfer reactions: the ferredoxin/flavodoxin/ferredoxin:NADP+ reductase system from Anabaena

artículo científico publicado en 1998

Quaternary organization in a bifunctional prokaryotic FAD synthetase: Involvement of an arginine at its adenylyltransferase module on the riboflavin kinase activity

artículo científico publicado en 2015

Role of key residues at the flavin mononucleotide (FMN):adenylyltransferase catalytic site of the bifunctional riboflavin kinase/flavin adenine dinucleotide (FAD) Synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2012

Role of specific residues in coenzyme binding, charge-transfer complex formation, and catalysis in Anabaena ferredoxin NADP+-reductase

artículo científico publicado en 2010

Specific Features for the Competent Binding of Substrates at the FMN Adenylyltransferase Site of FAD Synthase from Corynebacterium ammoniagenes

artículo científico publicado en 2019

Spectral and catalytic properties of aryl-alcohol oxidase, a fungal flavoenzyme acting on polyunsaturated alcohols.

artículo científico publicado en 2005

Structural analysis of FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2008

Structural and magnetic characterisation of the haem core of ferricytochromes c 6

Structural backgrounds for the formation of a catalytically competent complex with NADP(H) during hydride transfer in ferredoxin-NADP(+) reductases

artículo científico publicado en 2012

Structural basis of the catalytic role of Glu301 inAnabaena PCC 7119 ferredoxin-NADP+ reductase revealed by x-ray crystallography

Structural insights into the synthesis of FMN in prokaryotic organisms

artículo científico publicado en 2015

Structure-function relationships in Anabaena ferredoxin/ferredoxin:NADP(+) reductase electron transfer: insights from site-directed mutagenesis, transient absorption spectroscopy and X-ray crystallography

artículo científico publicado en 2002

Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry

artículo científico publicado en 2012

Substrate diffusion and oxidation in GMC oxidoreductases: an experimental and computational study on fungal aryl-alcohol oxidase.

artículo científico publicado en 2011

The C-terminal extension of bacterial flavodoxin-reductases: involvement in the hydride transfer mechanism from the coenzyme

artículo científico publicado en 2014

The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity

artículo científico publicado en 2020

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements.

artículo científico publicado en 2017

The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis.

artículo científico publicado en 2018

The apoptosis-inducing factor family: Moonlighting proteins in the crosstalk between mitochondria and nuclei

artículo científico publicado en 2020

The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism

artículo científico publicado en 2005

The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?

artículo científico publicado en 2013

The prokaryotic FAD synthetase family: a potential drug target

artículo científico publicado en 2013

The puzzle of ligand binding to Corynebacterium ammoniagenes FAD synthetase

artículo científico publicado en 2009

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

artículo científico publicado en 2017

Theoretical Analysis of the Electron Spin Density Distribution of the Flavin Semiquinone Isoalloxazine Ring within Model Protein Environments

Theoretical Study of the Mechanism of the Hydride Transfer between Ferredoxin–NADP+ Reductase and NADP+: The Role of Tyr303

scientific article published in 2012

Unexpected diversity of ferredoxin-dependent thioredoxin reductases in cyanobacteria

artículo científico publicado en 2021

W196 and the <i>β</i>-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor

artículo científico publicado en 2021

Lista de obras de Milagros Medina

A laser flash absorption spectroscopy study of Anabaena sp. PCC 7119 flavodoxin photoreduction by photosystem I particles from spinach

Arabidopsis FNRL protein is an NADPH-dependent chloroplast oxidoreductase resembling bacterial ferredoxin-NADP+ reductases

Binding thermodynamics of ferredoxin:NADP+ reductase: two different protein substrates and one energetics

CW-EPR and ENDOR study of cytochrome c6 from Anabaena PCC 7119.

Characterization of cytochrome c 6 from the cyanobacterium Anabaena PCC 7119

Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase

Crystal Structure of the FAD-Containing Ferredoxin-NADP+Reductase from the Plant PathogenXanthomonas axonopodispv. citri

Crystallization and preliminary X-ray diffraction studies of FAD synthetase from Corynebacterium ammoniagenes

Crystals of Anabaena PCC 7119 ferredoxin-NADP+ reductase

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases.

Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface

Electron spin echo envelope modulation studies of the semiquinone anion radical of cholesterol oxidase from Brevibacterium sterolicum

Electron transferases

Evolutionary divergence of chloroplast FAD synthetase proteins ⬇️

Exact analysis of heterotropic interactions in proteins: Characterization of cooperative ligand binding by isothermal titration calorimetry

External loops at the ferredoxin-NADP(+) reductase protein-partner binding cavity contribute to substrates allocation

Flavin photochemistry in the analysis of electron transfer reactions: role of charged and hydrophobic residues at the carboxyl terminus of ferredoxin-NADP(+) reductase in the interaction with its substrates

Flavoproteins and flavoenzymes with biomedical and therapeutic impact

Histones cause aggregation and fusion of lipid vesicles containing phosphatidylinositol-4-phosphate

Hyperfine correlation spectroscopy and electron spin echo envelope modulation spectroscopy study of the two coexisting forms of the hemeprotein cytochrome c6 from Anabaena Pcc7119.

Identification of arginyl residues involved in the binding of ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 to its substrates

In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

Insights into the FMNAT Active Site of FAD Synthase: Aromaticity is Essential for Flavin Binding and Catalysis ⬇️

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

Key residues at the riboflavin kinase catalytic site of the bifunctional riboflavin kinase/FMN adenylyltransferase from Corynebacterium ammoniagenes

Kinetic and chemical characterization of aldehyde oxidation by fungal aryl-alcohol oxidase

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

Lysine residues on ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 involved in substrate binding

Mechanism of coenzyme recognition and binding revealed by crystal structure analysis of ferredoxin-NADP+ reductase complexed with NADP+

Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase.

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

Oligomeric state in the crystal structure of modular FAD synthetase provides insights into its sequential catalysis in prokaryotes

Protein dynamics promote hydride tunnelling in substrate oxidation by aryl-alcohol oxidase

Protein motifs involved in coenzyme interaction and enzymatic efficiency in anabaena ferredoxin-NADP+ reductase

Protein-protein interaction in electron transfer reactions: the ferredoxin/flavodoxin/ferredoxin:NADP+ reductase system from Anabaena

Quaternary organization in a bifunctional prokaryotic FAD synthetase: Involvement of an arginine at its adenylyltransferase module on the riboflavin kinase activity

Role of key residues at the flavin mononucleotide (FMN):adenylyltransferase catalytic site of the bifunctional riboflavin kinase/flavin adenine dinucleotide (FAD) Synthetase from Corynebacterium ammoniagenes

Role of specific residues in coenzyme binding, charge-transfer complex formation, and catalysis in Anabaena ferredoxin NADP+-reductase

Specific Features for the Competent Binding of Substrates at the FMN Adenylyltransferase Site of FAD Synthase from Corynebacterium ammoniagenes

Spectral and catalytic properties of aryl-alcohol oxidase, a fungal flavoenzyme acting on polyunsaturated alcohols.

Structural analysis of FAD synthetase from Corynebacterium ammoniagenes

Structural and magnetic characterisation of the haem core of ferricytochromes c 6

Structural backgrounds for the formation of a catalytically competent complex with NADP(H) during hydride transfer in ferredoxin-NADP(+) reductases

Structural basis of the catalytic role of Glu301 inAnabaena PCC 7119 ferredoxin-NADP+ reductase revealed by x-ray crystallography

Structural insights into the synthesis of FMN in prokaryotic organisms

Structure-function relationships in Anabaena ferredoxin/ferredoxin:NADP(+) reductase electron transfer: insights from site-directed mutagenesis, transient absorption spectroscopy and X-ray crystallography

Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry

Substrate diffusion and oxidation in GMC oxidoreductases: an experimental and computational study on fungal aryl-alcohol oxidase.

The C-terminal extension of bacterial flavodoxin-reductases: involvement in the hydride transfer mechanism from the coenzyme

The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements.

The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis.

The apoptosis-inducing factor family: Moonlighting proteins in the crosstalk between mitochondria and nuclei

The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism

The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?

The prokaryotic FAD synthetase family: a potential drug target

The puzzle of ligand binding to Corynebacterium ammoniagenes FAD synthetase

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

Theoretical Analysis of the Electron Spin Density Distribution of the Flavin Semiquinone Isoalloxazine Ring within Model Protein Environments

Theoretical Study of the Mechanism of the Hydride Transfer between Ferredoxin–NADP+ Reductase and NADP+: The Role of Tyr303

Unexpected diversity of ferredoxin-dependent thioredoxin reductases in cyanobacteria

W196 and the <i>β</i>-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor