Lista de obras - John Hiscott - Dominio Público Uruguay

A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization

artículo científico publicado en 2005

A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers

artículo científico publicado en 2010

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

artículo científico publicado en 2005

Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.

artículo científico publicado en 2006

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity

artículo científico publicado en 2004

Additive activity between the trans-activation response RNA-binding protein, TRBP2, and cyclin T1 on HIV type 1 expression and viral production in murine cells

artículo científico publicado en 2003

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation

artículo científico publicado en 2019

Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon.

artículo científico publicado en 2015

BCL-2 Inhibitors Sensitize Therapy-resistant Chronic Lymphocytic Leukemia Cells to VSV Oncolysis ⬇️

artículo científico publicado el 21 de mayo de 2013

Cell-specific regulation of TRBP1 promoter by NF-Y transcription factor in lymphocytes and astrocytes

artículo científico publicado en 2006

Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells

artículo científico publicado en 2014

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis.

artículo científico publicado en 2008

Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response

artículo científico publicado en 2007

Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis

artículo científico publicado en 2003

Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation

artículo científico publicado en 2014

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

artículo científico publicado en 2015

Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus

artículo científico publicado en 2016

Differential regulation of HIV-1 clade-specific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivator.

artículo científico publicado en 2002

Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7

artículo científico publicado en 2009

Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7

artículo científico publicado en 2010

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage

artículo científico publicado en 2006

Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages

artículo científico publicado en 2006

Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

artículo científico publicado en 2015

Functional analysis of a dominant negative mutation of interferon regulatory factor 5

artículo científico publicado en 2009

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

artículo científico publicado en 2005

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

artículo científico publicado en 2015

HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation

artículo científico publicado en 2016

HTLV-1 Evades Type I Interferon Antiviral Signaling by Inducing the Suppressor of Cytokine Signaling 1 (SOCS1) ⬇️

artículo científico publicado el 4 de noviembre de 2010

HTLV-1 Tax-mediated inhibition of FOXO3a activity is critical for the persistence of terminally differentiated CD4+ T cells

artículo científico publicado en 2014

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression

artículo científico publicado en 2006

Hostile takeovers: viral appropriation of the NF-kB pathway

artículo científico publicado en 2001

IRF-4 activities in HTLV-I-induced T cell leukemogenesis

artículo científico publicado en 2002

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon

artículo científico publicado en 2005

Intact type I Interferon production and IRF7 function in sooty mangabeys

artículo científico publicado en 2013

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

artículo científico publicado en 2014

MasterCARD: a priceless link to innate immunity

artículo científico publicado en 2006

Mechanisms of Zika Virus Infection and Neuropathogenesis

artículo científico publicado en 2016

Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.

artículo científico publicado en 2015

Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

artículo científico publicado en 2002

On the TRAIL to apoptosis

artículo científico publicado en 2002

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription

artículo científico publicado en 2002

Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon

artículo científico publicado en 2005

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I ⬇️

artículo científico publicado el 17 de noviembre de 2010

Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression ⬇️

artículo científico publicado el 7 de junio de 2012

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease

artículo científico publicado en 2006

Regulation of IFN regulatory factor 4 expression in human T cell leukemia virus-I-transformed T cells

artículo científico publicado en 2002

Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.

artículo científico publicado en 2005

Repression of DNA repair mechanisms in IRF-4-expressing and HTLV-I-infected T lymphocytes

artículo científico publicado en 2005

Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines

artículo científico publicado en 2006

STING-ing the antiviral pathway

artículo científico publicado en 2009

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

artículo científico publicado en 2015

Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection

artículo científico publicado en 2017

Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity

artículo científico publicado en 2013

Targeting the apoptotic pathway with BCL-2 inhibitors sensitizes primary chronic lymphocytic leukemia cells to vesicular stomatitis virus-induced oncolysis

artículo científico publicado en 2008

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

artículo científico publicado en 2009

The interferon antiviral response: from viral invasion to evasion

artículo científico publicado en 2002

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

artículo científico publicado en 2012

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

artículo científico publicado en 2002

Triggering the innate antiviral response through IRF-3 activation

artículo científico publicado en 2007

Triggering the interferon antiviral response through an IKK-related pathway

artículo científico publicado en 2003

Triptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis

artículo científico publicado en 2013

Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression.

artículo científico publicado en 2006

Ub surprised: viral ovarian tumor domain proteases remove ubiquitin and ISG15 conjugates

artículo científico publicado en 2007

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter

artículo científico publicado en 2009

VSV Oncolysis in Combination With the BCL-2 Inhibitor Obatoclax Overcomes Apoptosis Resistance in Chronic Lymphocytic Leukemia ⬇️

artículo científico publicado el 14 de septiembre de 2010

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

artículo científico publicado en 2003

Vesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation

artículo científico publicado en 2008

Vesicular stomatitis virus oncolytic treatment interferes with tumor-associated dendritic cell functions and abrogates tumor antigen presentation

artículo científico publicado en 2011

Lista de obras de John Hiscott

A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization

A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.

Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity

Additive activity between the trans-activation response RNA-binding protein, TRBP2, and cyclin T1 on HIV type 1 expression and viral production in murine cells

An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation

Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon.

BCL-2 Inhibitors Sensitize Therapy-resistant Chronic Lymphocytic Leukemia Cells to VSV Oncolysis ⬇️

Cell-specific regulation of TRBP1 promoter by NF-Y transcription factor in lymphocytes and astrocytes

Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis.

Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response

Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis

Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus

Differential regulation of HIV-1 clade-specific B, C, and E long terminal repeats by NF-kappaB and the Tat transactivator.

Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7

Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage

Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages

Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant

Functional analysis of a dominant negative mutation of interferon regulatory factor 5

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation

HTLV-1 Evades Type I Interferon Antiviral Signaling by Inducing the Suppressor of Cytokine Signaling 1 (SOCS1) ⬇️

HTLV-1 Tax-mediated inhibition of FOXO3a activity is critical for the persistence of terminally differentiated CD4+ T cells

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression

Hostile takeovers: viral appropriation of the NF-kB pathway

IRF-4 activities in HTLV-I-induced T cell leukemogenesis

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon

Intact type I Interferon production and IRF7 function in sooty mangabeys

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma

MasterCARD: a priceless link to innate immunity

Mechanisms of Zika Virus Infection and Neuropathogenesis

Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.

Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

On the TRAIL to apoptosis

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription

Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I ⬇️

Recruitment of Histone Deacetylase 3 to the Interferon-A Gene Promoters Attenuates Interferon Expression ⬇️

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease

Regulation of IFN regulatory factor 4 expression in human T cell leukemia virus-I-transformed T cells

Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.

Repression of DNA repair mechanisms in IRF-4-expressing and HTLV-I-infected T lymphocytes

Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines

STING-ing the antiviral pathway

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists

Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection

Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity

Targeting the apoptotic pathway with BCL-2 inhibitors sensitizes primary chronic lymphocytic leukemia cells to vesicular stomatitis virus-induced oncolysis

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

The interferon antiviral response: from viral invasion to evasion

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

Triggering the innate antiviral response through IRF-3 activation

Triggering the interferon antiviral response through an IKK-related pathway

Triptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis

Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression.

Ub surprised: viral ovarian tumor domain proteases remove ubiquitin and ISG15 conjugates

Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter

VSV Oncolysis in Combination With the BCL-2 Inhibitor Obatoclax Overcomes Apoptosis Resistance in Chronic Lymphocytic Leukemia ⬇️

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents

Vesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation

Vesicular stomatitis virus oncolytic treatment interferes with tumor-associated dendritic cell functions and abrogates tumor antigen presentation