Lista de obras - Simona Maria Monti - Dominio Público Uruguay

2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site

artículo científico publicado en 2020

A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases

artículo científico publicado en 2016

A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors

A comparison of color formation and maillard reaction products of a lactose-lysine and lactose-N(alpha)-acetyllysine model system

artículo científico publicado en 2000

A new FcεRI receptor-mimetic peptide (PepE) that blocks IgE binding to its high affinity receptor and prevents mediator release from RBL 2H3 cells.

artículo científico publicado en 2011

A virulence factor encoded by a polydnavirus confers tolerance to transgenic tobacco plants against lepidopteran larvae, by impairing nutrient absorption.

artículo científico publicado en 2014

Analysis of bacterial lipodepsipeptides by matrix-assisted laser desorption/ionisation time-of-flight and high-performance liquid chromatography with electrospray mass spectrometry.

artículo científico publicado en 2001

Anticancer carbonic anhydrase inhibitors: a patent review (2008 - 2013).

artículo científico

Benzoxaborole as a new chemotype for carbonic anhydrase inhibition

artículo científico publicado en 2016

Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

artículo científico publicado en 2008

Biochemical characterization of the chloroplastic β-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze".

artículo científico publicado en 2013

Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX.

artículo científico publicado en 2018

CDCA1 From Thalassiosira weissflogii as Representative Member of ζ-Class CAs: General Features and Biotechnological Applications

Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii

artículo científico publicado en 2015

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

scientific article published on 14 October 2020

Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX

article

Carbonic Anhydrase VII

Carbonic anhydrase IX as a target for designing novel anticancer drugs.

artículo científico

Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors

artículo científico publicado en 2012

Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors

artículo científico publicado en 2009

Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV

artículo científico publicado en 2010

Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies

artículo científico publicado en 2007

Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells

artículo científico publicado en 2012

Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system.

artículo científico publicado en 2001

Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems

artículo científico publicado en 1999

Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

artículo científico publicado en 2009

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide

artículo científico publicado en 2010

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

artículo científico publicado en 2009

Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor.

artículo científico publicado en 2018

Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense

artículo científico publicado en 2015

Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors

artículo científico publicado en 2016

Development and Yield Traits Indicate That the Constitutive Wound Response Phenotype of Prosystemin Overexpressing Tomato Plants Entails No Fitness Penalty

artículo científico publicado en 2021

Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements

artículo científico publicado en 2017

Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors

artículo científico publicado en 2015

Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.

artículo científico publicado en 2016

Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment.

artículo científico publicado en 2017

Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal

scientific article published on 09 July 2018

Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata

scientific article published on 11 December 2011

Editorial (Thematic Issue: Bacterial Metallo-Enzymes as Drug Targets).

artículo científico publicado en 2016

Evolution of protein bound Maillard reaction end-products and free Amadori compounds in low lactose milk in presence of fructosamine oxidase I.

artículo científico publicado en 2016

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

artículo científico publicado en 2019

Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity

artículo científico publicado en 2019

Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety

artículo científico publicado en 2018

Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15.

artículo científico publicado en 2008

Extraction of azadirachtin A from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS

artículo científico publicado en 1999

Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk

artículo científico publicado en 2013

Gadd45 beta forms a homodimeric complex that binds tightly to MKK7.

artículo científico publicado en 2008

Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes

artículo científico

Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors

artículo científico publicado en 2014

Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors.

artículo científico publicado en 2015

Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates

artículo científico publicado en 2013

Identification of a beta-lactoglobulin lactosylation site.

artículo científico publicado en 1998

Identification of non-specific Lipid Transfer Protein gene family members in Solanum lycopersicum and insights into the features of Sola l 3 protein

artículo científico publicado en 2019

IgE-binding properties and selectivity of peptide mimics of the FcvarepsilonRI binding site

artículo científico publicado en 2009

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one

artículo científico publicado en 2018

Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding

artículo científico publicado en 2018

Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions.

artículo científico publicado en 2010

Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides.

artículo científico publicado en 2018

Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties

artículo científico publicado en 2015

Insights into the Structural Basis of the GADD45β-mediated Inactivation of the JNK Kinase, MKK7/JNKK2

artículo científico publicado en 2007

Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations

artículo científico publicado en 2017

Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage

artículo científico publicado en 2016

Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain

scientific article published on 17 November 2020

Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors

artículo científico publicado en 2016

Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis

artículo científico publicado en 2013

L-Histidinol Dehydrogenase as a New Target for Old Diseases.

artículo científico publicado en 2016

LC/MS Analysis and Antioxidative Efficiency of Maillard Reaction Products from a Lactose−Lysine Model System

artículo científico publicado en 1999

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

scientific article published on 29 August 2019

Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.

artículo científico publicado en 2016

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

artículo científico publicado en 2013

Out of the active site binding pocket for carbonic anhydrase inhibitors

artículo científico publicado en 2015

Polyclonal antibodies against fusaproliferin

artículo científico publicado en 1999

Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.

artículo científico publicado en 2017

Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein.

artículo científico publicado en 2017

Protective Role of Carbonic Anhydrases III and VII in Cellular Defense Mechanisms upon Redox Unbalance

artículo científico publicado en 2018

Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants

scholarly article by Rita Del Giudice published in February 2016

Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists.

artículo científico publicado en 2009

Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV.

artículo científico publicado en 2008

Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII.

artículo científico publicado en 2010

Residues 762-801 of PLD1 mediate the interaction with PED/PEA15.

artículo científico publicado en 2010

Role of Antioxidants in the Protection from Aging-Related Diseases

artículo científico publicado en 2019

Self-association regions in the CARD of Bcl-10.

artículo científico publicado en 2009

Simultaneous Determination of Beauvericin, Enniatins, and Fusaproliferin by High Performance Liquid Chromatography†

artículo científico publicado en 2000

Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry

artículo científico publicado en 2014

Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii

artículo científico publicado en 2012

Structural basis for the rational design of new anti-Brucella agents: the crystal structure of the C366S mutant of L-histidinol dehydrogenase from Brucella suis

artículo científico publicado en 2014

Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties

scientific article published on 11 January 2017

Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells.

artículo científico publicado en 2008

The Amazing World of IDPs in Human Diseases

scientific article published in 2021

The Amazing World of IDPs in Human Diseases II

scientific article published in 2022

The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior

artículo científico publicado en 2018

The chemical synthesis of the GstI protein by NCL on a X-Met site

artículo científico publicado en 2006

The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex

artículo científico publicado en 2010

The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors

artículo científico publicado en 2014

The zinc - but not cadmium - containing ζ-carbonic from the diatom Thalassiosira weissflogii is potently activated by amines and amino acids

artículo científico publicado en 2018

Thermal-stable carbonic anhydrases: a structural overview.

artículo científico

Thermostable Carbonic Anhydrases in Biotechnological Applications

artículo científico publicado en 2015

X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor

artículo científico publicado en 2015

X-ray structure of the first `extremo-α-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1

artículo científico publicado en 2013

α-CAs from Photosynthetic Organisms

artículo científico publicado en 2022

Lista de obras de Simona Maria Monti

2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site

A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases

A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors

A comparison of color formation and maillard reaction products of a lactose-lysine and lactose-N(alpha)-acetyllysine model system

A new FcεRI receptor-mimetic peptide (PepE) that blocks IgE binding to its high affinity receptor and prevents mediator release from RBL 2H3 cells.

A virulence factor encoded by a polydnavirus confers tolerance to transgenic tobacco plants against lepidopteran larvae, by impairing nutrient absorption.

Analysis of bacterial lipodepsipeptides by matrix-assisted laser desorption/ionisation time-of-flight and high-performance liquid chromatography with electrospray mass spectrometry.

Anticancer carbonic anhydrase inhibitors: a patent review (2008 - 2013).

Benzoxaborole as a new chemotype for carbonic anhydrase inhibition

Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

Biochemical characterization of the chloroplastic β-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze".

Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX.

CDCA1 From Thalassiosira weissflogii as Representative Member of ζ-Class CAs: General Features and Biotechnological Applications

Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX

Carbonic Anhydrase VII

Carbonic anhydrase IX as a target for designing novel anticancer drugs.

Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors

Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors

Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV

Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies

Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells

Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system.

Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems

Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor.

Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense

Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors

Development and Yield Traits Indicate That the Constitutive Wound Response Phenotype of Prosystemin Overexpressing Tomato Plants Entails No Fitness Penalty

Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements

Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors

Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.

Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment.

Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal

Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata

Editorial (Thematic Issue: Bacterial Metallo-Enzymes as Drug Targets).

Evolution of protein bound Maillard reaction end-products and free Amadori compounds in low lactose milk in presence of fructosamine oxidase I.

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity

Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety

Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15.

Extraction of azadirachtin A from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS

Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk

Gadd45 beta forms a homodimeric complex that binds tightly to MKK7.

Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes

Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors

Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors.

Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates

Identification of a beta-lactoglobulin lactosylation site.

Identification of non-specific Lipid Transfer Protein gene family members in Solanum lycopersicum and insights into the features of Sola l 3 protein

IgE-binding properties and selectivity of peptide mimics of the FcvarepsilonRI binding site

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one

Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding

Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions.

Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides.

Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties

Insights into the Structural Basis of the GADD45β-mediated Inactivation of the JNK Kinase, MKK7/JNKK2

Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations

Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage

Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain

Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors

Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis

L-Histidinol Dehydrogenase as a New Target for Old Diseases.

LC/MS Analysis and Antioxidative Efficiency of Maillard Reaction Products from a Lactose−Lysine Model System

Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests

Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Out of the active site binding pocket for carbonic anhydrase inhibitors

Polyclonal antibodies against fusaproliferin

Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.

Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein.

Protective Role of Carbonic Anhydrases III and VII in Cellular Defense Mechanisms upon Redox Unbalance

Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants

Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists.

Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV.

Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII.