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Lista de obras de Jacques-Philippe Colletier

Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations

artículo científico publicado en 2011

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

artículo científico publicado en 2017

Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime

artículo científico publicado en 2009

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

artículo científico publicado en 2022

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure

artículo científico publicado en 2016

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

artículo científico publicado en 2016

Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor

artículo científico publicado en 2014

Hydration water mobility is enhanced around tau amyloid fibers

artículo científico publicado en 2015

Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry

artículo científico publicado en 2013

Molecular basis for amyloid-  polymorphism

artículo científico publicado en 2011

Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure Analysis

artículo científico publicado en 2011

Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions

artículo científico publicado en 2012

Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP

artículo científico publicado en 2016

Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

artículo científico publicado en 2020

Shoot-and-Trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography

artículo científico publicado en 2008

Slow conformational exchange and overall rocking motion in ubiquitin protein crystals

artículo científico publicado en 2017

Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation

artículo científico publicado en 2010

Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents

artículo científico publicado en 2015

Structure-guided simulations illuminate the mechanism of ATP transport through VDAC1

artículo científico publicado en 2014

The C. elegans GATA transcription factor elt-2 mediates distinct transcriptional responses and opposite infection outcomes towards different Bacillus thuringiensis strains

scientific article published on 24 September 2020

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

artículo científico publicado en 2017

The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating

artículo científico publicado en 2008

Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation

artículo científico publicado en 2015

Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography

artículo científico publicado en 2007

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