Lista de obras - Martin Högbom - Dominio Público Uruguay

A High Throughput Method for the Detection of Metalloproteins on a Microgram Scale

artículo científico publicado en 2005

A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold

artículo científico publicado en 2009

A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals.

artículo científico publicado en 2018

A dynamic C-terminal segment in the Mycobacterium tuberculosis Mn/Fe R2lox protein can adopt a helical structure with possible functional consequences

artículo científico publicado en 2012

A protein carboxylate coordinated oxo-centered tri-nuclear iron complex with possible implications for ferritin mineralization

artículo científico publicado en 2004

A rapid expression and purification condition screening protocol for membrane protein structural biology

artículo científico publicado en 2017

ADP-ribosylation, a mechanism regulating nitrogenase activity

artículo científico publicado en 2013

Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase

Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins

artículo científico

Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase

artículo científico publicado en 2012

Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase

artículo científico publicado en 2012

Biological relevance of natural alpha-toxin fragments from Staphylococcus aureus

artículo científico publicado en 2010

Channel-forming abilities of spontaneously occurring alpha-toxin fragments from Staphylococcus aureus

artículo científico publicado en 2010

Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency (17)O-Hyperfine EPR Spectroscopies and Density Functional Theory.

artículo científico publicado en 2015

Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

artículo científico publicado en 2019

Comparative Structural Analysis of Human DEAD-Box RNA Helicases

artículo científico publicado en 2010

Conformational changes in Apolipoprotein N-acyltransferase (Lnt)

scientific article published on 20 January 2020

Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP

artículo científico publicado en 2007

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

artículo científico publicado en 2011

Crystal structure of the P2 C-repressor: a binder of non-palindromic direct DNA repeats

artículo científico publicado en 2010

Crystal structure of the bacteriophage P2 integrase catalytic domain

artículo científico publicado en 2015

Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes

artículo científico publicado en 2002

Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis

artículo científico publicado en 2017

Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase from Escherichia coli: carboxylate shifts with implications for O2 activation and radical generation

artículo científico publicado en 2001

Crystals of the ribonucleotide reductase R2 protein from Chlamydia trachomatis obtained by heavy-atom co-crystallization

scientific article published on 23 January 2004

Current status and future opportunities for serial crystallography at MAX IV Laboratory

scientific article published on 21 August 2020

Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein

artículo científico publicado en 2013

Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-A x-ray data

artículo científico publicado en 2003

Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

artículo científico publicado en 2016

Driving protein conformational changes with light: Photoinduced structural rearrangement in a heterobimetallic oxidase.

artículo científico publicado en 2017

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

artículo científico publicado en 2017

Electronic structural flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

artículo científico publicado en 2014

Ether cross-link formation in the R2-like ligand-binding oxidase

scientific article published on 26 June 2018

Expression and Subcellular Distribution of GFP-Tagged Human Tetraspanin Proteins in Saccharomyces cerevisiae

artículo científico publicado en 2015

Functional and structural characteristics of bacterial proteins that bind host cytokines

artículo científico publicado en 2017

High throughput methods for analyzing transition metals in proteins on a microgram scale

artículo científico publicado en 2008

Inhibition of chlamydial class Ic ribonucleotide reductase by C-terminal peptides from protein R2.

artículo científico publicado en 2011

Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1

artículo científico publicado en 2007

Interactions between the Aggregatibacter actinomycetemcomitans secretin HofQ and host cytokines indicate a link between natural competence and interleukin-8 uptake

artículo científico publicado en 2018

Isolation of yeast complex IV in native lipid nanodiscs

artículo científico publicado en 2016

Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein

artículo científico publicado en 2020

Kinetics and structural features of dimeric Gln-dependent bacterial NAD+ synthetases suggest evolutionary adaptation to available metabolites.

artículo científico publicado en 2018

Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD

artículo científico publicado en 2019

Mechanism of ADP-ribosylation removal revealed by the structure and ligand complexes of the dimanganese mono-ADP-ribosylhydrolase DraG

artículo científico publicado en 2009

Metal use in ribonucleotide reductase R2, di-iron, di-manganese and heterodinuclear—an intricate bioinorganic workaround to use different metals for the same reaction ⬇️

artículo científico publicado el 25 de enero de 2011

Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens

scientific article published in Nature

Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome

artículo científico publicado en 2013

Nitrogenase Mechanism. A dynamic tool for nitrogen reduction

artículo científico publicado en 2014

Penicillin-binding protein 5 can form a homo-oligomeric complex in the inner membrane of Escherichia coli

artículo científico publicado en 2011

Production of human tetraspanin proteins in Escherichia coli

artículo científico publicado en 2012

Proton uptake and pKa changes in the uncoupled Asn139Cys variant of cytochrome c oxidase

artículo científico publicado en 2013

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

artículo científico publicado en 2011

Protonation State of MnFe and FeFe Cofactors in a Ligand-Binding Oxidase Revealed by X-ray Absorption, Emission, and Vibrational Spectroscopy and QM/MM Calculations

artículo científico publicado en 2016

Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access

scientific article published on 13 August 2019

Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli

artículo científico publicado en 2001

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

artículo científico publicado en 2013

Scavenging of superoxide by a membrane-bound superoxide oxidase

artículo científico publicado en 2018

Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation

artículo científico publicado en 2018

Solving a new R2lox protein structure by microcrystal electron diffraction

artículo científico publicado en 2019

Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

artículo científico publicado en 2015

Structural and mutational studies of the carboxylate cluster in iron-free ribonucleotide reductase R2.

artículo científico publicado en 2004

Structural basis for recognition by an in vitro evolved affibody

artículo científico publicado en 2003

Structural insight into DNA binding and oligomerization of the multifunctional Cox protein of bacteriophage P2

artículo científico publicado en 2014

Structural mechanics of the pH-dependent activity of beta-carbonic anhydrase from Mycobacterium tuberculosis

scientific journal article

Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis

artículo científico publicado en 2008

Structure and Cooperativity of the Cytosolic Domain of the CorA Mg2+ Channel from Escherichia coli

artículo científico publicado en 2017

Structure and function of carbonic anhydrases from Mycobacterium tuberculosis

scientific journal article

Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis

scientific article published on 05 December 2018

Structure of a ribonucleotide reductase R2 protein radical

artículo científico publicado en 2023

Structure of human argininosuccinate synthetase

artículo científico publicado en 2008

Structure of phosphatidylinositol phosphate synthase reveals mechanism of substrate binding and metal catalysis

article published in 2019

Structure of the TatC core of the twin-arginine protein transport system

artículo científico publicado en 2012

Structure of the high-valent FeIIIFeIV state in ribonucleotide reductase (RNR) of Chlamydia trachomatis--combined EPR, 57Fe-, 1H-ENDOR and X-ray studies

artículo científico publicado en 2007

The Crystal Structure of an Azide Complex of the Diferrous R2 Subunit of Ribonucleotide Reductase Displays a Novel Carboxylate Shift with Important Mechanistic Implications for Diiron-Catalyzed Oxygen Activation

artículo científico publicado en 1999

The Mycobacterium tuberculosis very-long-chain fatty acyl-CoA synthetase: structural basis for housing lipid substrates longer than the enzyme

artículo científico publicado en 2012

The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity

artículo científico publicado en 2009

The ammonium transporter AmtB and the PII signal transduction protein GlnZ are required to inhibit DraG in Azospirillum brasilense

scientific article published on 12 February 2019

The class Ib ribonucleotide reductase from Mycobacterium tuberculosis has two active R2F subunits

scholarly article by Marta Hammerstad et al published August 2014 in Journal of Biological Inorganic Chemistry

The extra-membranous domains of the competence protein HofQ show DNA binding, flexibility and a shared fold with type I KH domains

artículo científico publicado en 2011

The manganese ion of the heterodinuclear Mn/Fe cofactor in Chlamydia trachomatis ribonucleotide reductase R2c is located at metal position 1.

scientific article published on 08 December 2011

The manganese/iron-carboxylate proteins: what is what, where are they, and what can the sequences tell us?

artículo científico publicado en 2010

The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass

artículo científico publicado en 2004

Tuning Escherichia coli for membrane protein overexpression

artículo científico publicado en 2008

Use of structural phylogenetic networks for classification of the ferritin-like superfamily

artículo científico publicado en 2012

X-ray reduction correlates with soaking accessibility as judged from four non-crystallographically related diiron sites

artículo científico publicado en 2012

Lista de obras de Martin Högbom

A High Throughput Method for the Detection of Metalloproteins on a Microgram Scale

A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold

A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals.

A dynamic C-terminal segment in the Mycobacterium tuberculosis Mn/Fe R2lox protein can adopt a helical structure with possible functional consequences

A protein carboxylate coordinated oxo-centered tri-nuclear iron complex with possible implications for ferritin mineralization

A rapid expression and purification condition screening protocol for membrane protein structural biology

ADP-ribosylation, a mechanism regulating nitrogenase activity

Assembly of a heterodinuclear Mn/Fe cofactor is coupled to tyrosine-valine ether cross-link formation in the R2-like ligand-binding oxidase

Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins

Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase

Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase

Biological relevance of natural alpha-toxin fragments from Staphylococcus aureus

Channel-forming abilities of spontaneously occurring alpha-toxin fragments from Staphylococcus aureus

Characterization of Oxygen Bridged Manganese Model Complexes Using Multifrequency (17)O-Hyperfine EPR Spectroscopies and Density Functional Theory.

Chemical flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

Comparative Structural Analysis of Human DEAD-Box RNA Helicases

Conformational changes in Apolipoprotein N-acyltransferase (Lnt)

Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

Crystal structure of the P2 C-repressor: a binder of non-palindromic direct DNA repeats

Crystal structure of the bacteriophage P2 integrase catalytic domain

Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes

Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis

Crystal structures of oxidized dinuclear manganese centres in Mn-substituted class I ribonucleotide reductase from Escherichia coli: carboxylate shifts with implications for O2 activation and radical generation

Crystals of the ribonucleotide reductase R2 protein from Chlamydia trachomatis obtained by heavy-atom co-crystallization

Current status and future opportunities for serial crystallography at MAX IV Laboratory

Direct observation of structurally encoded metal discrimination and ether bond formation in a heterodinuclear metalloprotein

Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-A x-ray data

Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins

Driving protein conformational changes with light: Photoinduced structural rearrangement in a heterobimetallic oxidase.

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

Electronic structural flexibility of heterobimetallic Mn/Fe cofactors: R2lox and R2c proteins

Ether cross-link formation in the R2-like ligand-binding oxidase

Expression and Subcellular Distribution of GFP-Tagged Human Tetraspanin Proteins in Saccharomyces cerevisiae

Functional and structural characteristics of bacterial proteins that bind host cytokines

High throughput methods for analyzing transition metals in proteins on a microgram scale

Inhibition of chlamydial class Ic ribonucleotide reductase by C-terminal peptides from protein R2.

Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1

Interactions between the Aggregatibacter actinomycetemcomitans secretin HofQ and host cytokines indicate a link between natural competence and interleukin-8 uptake

Isolation of yeast complex IV in native lipid nanodiscs

Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein

Kinetics and structural features of dimeric Gln-dependent bacterial NAD+ synthetases suggest evolutionary adaptation to available metabolites.

Location-specific quantification of protein-bound metal ions by X-ray anomalous dispersion: Q-XAD

Mechanism of ADP-ribosylation removal revealed by the structure and ligand complexes of the dimanganese mono-ADP-ribosylhydrolase DraG

Metal use in ribonucleotide reductase R2, di-iron, di-manganese and heterodinuclear—an intricate bioinorganic workaround to use different metals for the same reaction ⬇️

Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens

Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome

Nitrogenase Mechanism. A dynamic tool for nitrogen reduction

Penicillin-binding protein 5 can form a homo-oligomeric complex in the inner membrane of Escherichia coli

Production of human tetraspanin proteins in Escherichia coli

Proton uptake and pKa changes in the uncoupled Asn139Cys variant of cytochrome c oxidase

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

Protonation State of MnFe and FeFe Cofactors in a Ligand-Binding Oxidase Revealed by X-ray Absorption, Emission, and Vibrational Spectroscopy and QM/MM Calculations

Redox-induced structural changes in the di-iron and di-manganese forms of Bacillus anthracis ribonucleotide reductase subunit NrdF suggest a mechanism for gating of radical access

Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

Scavenging of superoxide by a membrane-bound superoxide oxidase

Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation

Solving a new R2lox protein structure by microcrystal electron diffraction

Structural Basis for Oxygen Activation at a Heterodinuclear Manganese/Iron Cofactor

Structural and mutational studies of the carboxylate cluster in iron-free ribonucleotide reductase R2.

Structural basis for recognition by an in vitro evolved affibody

Structural insight into DNA binding and oligomerization of the multifunctional Cox protein of bacteriophage P2

Structural mechanics of the pH-dependent activity of beta-carbonic anhydrase from Mycobacterium tuberculosis

Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis

Structure and Cooperativity of the Cytosolic Domain of the CorA Mg2+ Channel from Escherichia coli

Structure and function of carbonic anhydrases from Mycobacterium tuberculosis

Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis

Structure of a ribonucleotide reductase R2 protein radical

Structure of human argininosuccinate synthetase

Structure of phosphatidylinositol phosphate synthase reveals mechanism of substrate binding and metal catalysis

Structure of the TatC core of the twin-arginine protein transport system

Structure of the high-valent FeIIIFeIV state in ribonucleotide reductase (RNR) of Chlamydia trachomatis--combined EPR, 57Fe-, 1H-ENDOR and X-ray studies

The Crystal Structure of an Azide Complex of the Diferrous R2 Subunit of Ribonucleotide Reductase Displays a Novel Carboxylate Shift with Important Mechanistic Implications for Diiron-Catalyzed Oxygen Activation

The Mycobacterium tuberculosis very-long-chain fatty acyl-CoA synthetase: structural basis for housing lipid substrates longer than the enzyme

The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity

The ammonium transporter AmtB and the PII signal transduction protein GlnZ are required to inhibit DraG in Azospirillum brasilense

The class Ib ribonucleotide reductase from Mycobacterium tuberculosis has two active R2F subunits

The extra-membranous domains of the competence protein HofQ show DNA binding, flexibility and a shared fold with type I KH domains