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Lista de obras de Huib Ovaa

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

artículo científico publicado en 2017

A General Approach Towards Triazole-Linked Adenosine Diphosphate Ribosylated Peptides and Proteins

artículo científico publicado en 2017

A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation

artículo científico publicado en 2011

A MALDI-TOF Approach to Ubiquitin Ligase Activity

artículo científico publicado en 2018

A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function

artículo científico publicado el 19 de septiembre de 2011

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

artículo científico publicado en 2020

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

artículo científico publicado en 2016

A family of unconventional deubiquitinases with modular chain specificity determinants.

artículo científico publicado en 2018

A flexible MHC class I multimer loading system for large-scale detection of antigen-specific T cells.

artículo científico publicado en 2018

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo

artículo científico publicado en 2006

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents

artículo científico publicado en 2011

A modified epigenetics toolbox to study histone modifications on the nucleosome core.

artículo científico publicado en 2010

A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study

artículo científico publicado en 2014

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

artículo científico publicado en 2005

A peptide's perspective on antigen presentation to the immune system

artículo científico publicado en 2013

A stereoselective route towards highly functionalized 4,6-diaminocyclohexene derivatives

Active-site directed probes to report enzymatic action in the ubiquitin proteasome system

artículo científico publicado en 2007

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib

artículo científico publicado en 2005

Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell lines.

artículo científico publicado en 2006

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

artículo científico publicado en 2004

Advancing our Understanding of Ubiquitination Using the Ub-Toolkit.

artículo científico publicado en 2017

Allosteric control of Ubp6 and the proteasome via a bidirectional switch

artículo científico publicado en 2022

Altered peptide ligands revisited: vaccine design through chemically modified HLA-A2-restricted T cell epitopes

artículo científico publicado en 2014

An Interaction Landscape of Ubiquitin Signaling

artículo científico publicado en 2017

An LC-MS/MS method for quantification of the active abiraterone metabolite Δ(4)-abiraterone (D4A) in human plasma

artículo científico publicado en 2017

An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis

artículo científico publicado en 2015

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

artículo científico publicado en 2011

An expeditious route to phosphorus heterocycles based on ring-closing metathesis

Applications for chemical probes of proteolytic activity

artículo científico publicado en 2004

Automated online sequential isotope labeling for protein quantitation applied to proteasome tissue-specific diversity

artículo científico publicado en 2008

Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice

artículo científico publicado en 2012

Autotaxin/Lpar3 signaling regulates Kupffer's vesicle formation and left-right asymmetry in zebrafish

artículo científico publicado el 24 de octubre de 2012

BAP1/ASXL1 recruitment and activation for H2A deubiquitination.

artículo científico publicado en 2016

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

artículo científico publicado en 2020

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation

artículo científico publicado en 2010

CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib

artículo científico publicado en 2007

Catching a DUB in the act: novel ubiquitin-based active site directed probes

artículo científico publicado en 2014

ChemInform Abstract: An Expeditious Route to Phosphorus Heterocycles Based on Ring-Closing Metathesis

ChemInform Abstract: Synthesis of Phosphorus Mono- and Bicycles by Catalytic Ring-Closing Metathesis

Chemical Evolution of Autotaxin Inhibitors

artículo científico publicado el 15 de febrero de 2012

Chemical Modification of Influenza CD8+ T-Cell Epitopes Enhances Their Immunogenicity Regardless of Immunodominance

artículo científico publicado en 2016

Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs)

scientific article published on 05 August 2019

Chemical biology approaches to probe the proteome.

artículo científico publicado en 2008

Chemical biology of antigen presentation by MHC molecules

artículo científico publicado en 2013

Chemical proteomics profiling of proteasome activity

artículo científico publicado en 2006

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin

artículo científico publicado en 2010

Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy

artículo científico publicado en 2003

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

artículo científico publicado en 2002

Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases

artículo científico publicado en 2004

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons

scientific article published on 24 January 2019

Class I major histocompatibility complexes loaded by a periodate trigger

artículo científico publicado en 2009

Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.

artículo científico publicado en 2006

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7

artículo científico publicado en 2008

Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis

artículo científico publicado en 2013

Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2.

artículo científico publicado en 2013

Cover Picture: Development of an Activity-Based Probe for Autotaxin (ChemBioChem 16/2010)

scientific article published in 2010

Cracking the Ubiquitin Code: The Ubiquitin Toolbox

scientific article published on 01 November 2019

Creating molecules that modulate immune responses

article

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome

artículo científico publicado en 2006

DNP-Supported Solid-State NMR Spectroscopy of Proteins Inside Mammalian Cells

scientific article published on 19 July 2019

DUBs and disease: activity assays for inhibitor development.

artículo científico publicado en 2008

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules

artículo científico publicado en 2015

Design and use of conditional MHC class I ligands

artículo científico publicado en 2006

Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis

scientific article published on 19 December 2019

Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake

artículo científico publicado en 2015

Development of ADPribosyl ubiquitin analogs to study enzymes involved in Legionella infection

artículo científico publicado en 2020

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

artículo científico publicado en 2016

Development of Ubiquitin-Based Probe for Metalloprotease Deubiquitinases

artículo científico publicado en 2019

Development of a DUB-selective fluorogenic substrate

artículo científico publicado en 2019

Development of a Hypersensitive Periodate‐Cleavable Amino Acid that is Methionine‐ and Disulfide‐Compatible and its Application in MHC Exchange Reagents for T Cell Characterisation

artículo científico publicado el 2 de enero de 2013

Development of an activity-based probe for autotaxin

artículo científico publicado en 2010

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

scholarly article

Discovery and optimization of boronic acid based inhibitors of autotaxin

artículo científico publicado en 2010

Discovery of potent inhibitors of the lysophospholipase autotaxin

scientific article published on 14 October 2016

Disease-associated prion protein oligomers inhibit the 26S proteasome

artículo científico publicado en 2007

Dissecting Intracellular Proteolysis Using Small Molecule Inhibitors and Molecular Probes

Dissecting Intracellular Proteolysis Using Small Molecule Inhibitors and Molecular Probes

Diubiquitin-Based NMR Analysis: Interactions Between Lys6-Linked diUb and UBA Domain of UBXN1

artículo científico publicado en 2019

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism

scientific article published on 01 November 2018

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

artículo científico publicado en 2016

Drug discovery and assay development in the ubiquitin-proteasome system

artículo científico publicado en 2010

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

artículo científico publicado en 2013

Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

artículo científico publicado en 2013

Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies.

artículo científico publicado en 2018

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

artículo científico publicado en 2013

Editorial overview: Molecular immunology: targeting the immune system

artículo científico publicado en 2014

Editorial: Probing the Ubiquitin Landscape

artículo científico publicado en 2020

Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathy

artículo científico publicado en 2008

Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation

artículo científico publicado en 2017

Enhanced Delivery of Synthetic Labelled Ubiquitin into Live Cells by Using Next-Generation Ub-TAT Conjugates

artículo científico publicado en 2018

Enhanced delivery of synthetic ubiquitin into live cells using NextGen Ub-TAT conjugates

article

Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling

artículo científico publicado en 2014

Exploring the Versatility of the Covalent Thiol-Alkyne Reaction with Substituted Propargyl Warheads: A Deciding Role for the Cysteine Protease

artículo científico publicado en 2021

Fluorescence-based proteasome activity profiling.

artículo científico publicado en 2012

Generation of peptide MHC class I monomers and multimers through ligand exchange

scientific article published on 01 November 2009

Generation of peptide–MHC class I complexes through UV-mediated ligand exchange

scientific article published on 01 January 2006

Generation of the UFM1 Toolkit for Profiling UFM1-Specific Proteases and Ligases

artículo científico publicado en 2018

High-throughput T-cell epitope discovery through MHC peptide exchange

artículo científico publicado en 2009

Highlighting the Proteasome: Using Fluorescence to Visualize Proteasome Activity and Distribution

artículo científico publicado en 2019

Hitting the target

artículo científico publicado en 2015

Homeostasis of soluble proteins and the proteasome post nuclear envelope reformation in mitosis

scientific article published on 15 May 2019

How Chemical Synthesis of Ubiquitin Conjugates Helps To Understand Ubiquitin Signal Transduction

artículo científico publicado en 2016

How chemistry supports cell biology: the chemical toolbox at your service

artículo científico publicado en 2014

How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling

scientific article published on 01 January 2019

Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code

artículo científico publicado en 2019

IMI European Lead Factory — democratizing access to high-throughput screening

artículo científico

Identification and characterization of diverse OTU deubiquitinases in bacteria

scientific article published on 22 June 2020

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

artículo científico publicado en 2017

Immunotherapeutic potential for ceramide-based activators of iNKT cells

artículo científico publicado en 2005

Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways

artículo científico publicado en 2015

Inhibition of papain-like protease PLpro blocks SARS-CoV-2 spread and promotes anti-viral immunity

artículo científico publicado en 2020

Inhibition of the Deubiquitinase Usp14 Diminishes Direct MHC Class I Antigen Presentation

artículo científico publicado en 2017

Inhibition of transcription leads to rewiring of locus-specific chromatin proteomes

scientific article published on 18 March 2020

Integrating chemical and genetic silencing strategies to identify host kinase-phosphatase inhibitor networks that control bacterial infection

artículo científico publicado en 2013

Intermediate filament transcription in astrocytes is repressed by proteasome inhibition.

artículo científico publicado en 2009

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

artículo científico publicado en 2018

K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap

artículo científico publicado en 2020

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity

artículo científico publicado en 2019

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

scientific article published on 07 December 2020

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

artículo científico publicado en 2005

Lower expression of catalytic and structural subunits of the proteasome contributes to decreased proteolysis in peripheral blood T lymphocytes during aging.

artículo científico publicado en 2007

Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors

scientific article published on 30 June 2020

Mechanism and inhibition of SARS-CoV-2 PLpro

Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

scientific article published on 26 August 2020

Mechanism of UCH-L5 activation and inhibition by DEUBAD domains in RPN13 and INO80G.

artículo científico publicado en 2015

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

artículo científico publicado en 2011

Mechanism-based proteomics tools based on ubiquitin and ubiquitin-like proteins: crystallography, activity profiling, and protease identification

artículo científico publicado en 2005

Mechanism-based proteomics tools based on ubiquitin and ubiquitin-like proteins: synthesis of active site-directed probes

artículo científico publicado en 2005

Microwave-assisted diastereoselective two-step three-component synthesis for rapid access to drug-like libraries of substituted 3-amino-β-lactams

artículo científico publicado en 2017

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

artículo científico publicado en 2016

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15

scientific journal article

Mycobacterium tuberculosis Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates

artículo científico publicado en 2017

Mycobacterium tuberculosis prokaryotic ubiquitin-like protein-deconjugating enzyme is an unusual aspartate amidase

artículo científico publicado en 2012

Native chemical ligation at methionine bioisostere norleucine allows for N-terminal chemical protein ligation

scientific article published on 01 August 2018

Necessity of lysophosphatidic acid receptor 1 for development of arthritis

artículo científico publicado en 2013

Nedd8 hydrolysis by UCH proteases in Plasmodium parasites.

artículo científico publicado en 2019

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

artículo científico publicado en 2016

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

artículo científico publicado en 2010

Novel class of OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

artículo científico publicado en 2020

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

artículo científico publicado en 2013

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

artículo científico publicado en 2013

One-Step Chemical Synthesis of Native Met1-Linked Poly-Ubiquitin Chains

scientific article published on 07 November 2018

Opportunities for Small Molecules in Cancer Immunotherapy

scientific article published on 04 May 2020

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

artículo científico publicado en 2020

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage.

artículo científico publicado en 2015

Phosphoproteomic analysis with a solid-phase capture-release-tag approach

artículo científico publicado en 2005

Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit

artículo científico publicado en 2017

Probing the Specificity and Activity Profiles of the Proteasome Inhibitors Bortezomib and Delanzomib

artículo científico publicado el 16 de abril de 2012

Probing ubiquitin and SUMO conjugation and deconjugation

artículo científico publicado en 2018

Production and Thermal Exchange of Conditional Peptide-MHC I Multimers

scientific article published on 01 September 2019

Profiling DUBs and Ubl-specific proteases with activity-based probes

artículo científico publicado en 2019

Profiling proteasome activity in tissue with fluorescent probes

artículo científico publicado en 2007

Profiling the Activity of Deubiquitinating Enzymes Using Chemically Synthesized Ubiquitin-Based Probes.

artículo científico publicado en 2017

Proteasome Activation by Small Molecules.

artículo científico publicado en 2017

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

artículo científico publicado en 2017

Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide.

artículo científico publicado en 2018

Proteasome proteolytic profile is linked to Bcr-Abl expression

artículo científico publicado en 2009

Proteome-wide identification of ubiquitin interactions using UbIA-MS.

artículo científico publicado en 2018

Quantifying cross-tissue diversity in proteasome complexes by mass spectrometry

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

artículo científico publicado en 2019

Reactive glia show increased immunoproteasome activity in Alzheimer’s disease

artículo científico publicado el 19 de abril de 2013

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

artículo científico publicado en 2016

Recombination-induced tag exchange to track old and new proteins

artículo científico publicado en 2009

Release of Enzymatically Active Deubiquitinating Enzymes upon Reversible Capture by Disulfide Ubiquitin Reagents

artículo científico publicado en 2017

Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis

artículo científico publicado en 2008

SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme

artículo científico publicado en 2015

SUMO targets the APC/C to regulate transition from metaphase to anaphase.

artículo científico publicado en 2018

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

artículo científico publicado en 2019

Selective PKCδ Inhibitor B106 Elicits Uveal Melanoma Growth Inhibitory Effects Independent of Activated PKC Isoforms

artículo científico publicado en 2019

Sirtuin 1 Inhibiting Thiocyanates (S1th)-A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases

scientific article published on 30 April 2020

Small molecules that target the ubiquitin system

artículo científico publicado en 2020

Small-Molecule Inhibitors and Probes for Ubiquitin- and Ubiquitin-Like-Specific Proteases

artículo científico publicado en 2005

Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins

artículo científico publicado en 2004

Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.

artículo científico publicado en 2013

Strategies to enhance immunogenicity of cDNA vaccine encoded antigens by modulation of antigen processing

artículo científico publicado en 2016

Strategy for Development of Site-Specific Ubiquitin Antibodies

artículo científico publicado en 2020

Structural basis of substrate discrimination and integrin binding by autotaxin

artículo científico publicado en 2011

Structural basis of the specificity of USP18 toward ISG15.

artículo científico publicado en 2017

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate

artículo científico publicado en 2004

Structure-based design of novel boronic acid-based inhibitors of autotaxin

artículo científico publicado en 2011

Synthesis and evaluation of a selective fluorogenic Pup derived assay reagent for Dop, a potential drug target in Mycobacterium tuberculosis

artículo científico publicado en 2012

Synthesis of Atypical Diubiquitin Chains

artículo científico publicado el 1 de enero de 2012

Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer.

artículo científico publicado en 2017

Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitinating Enzyme SdeC

scientific article published on 18 May 2020

Synthesis of phosphorus mono- and bicycles by catalytic ring-closing metathesis

article published in 2001

Synthetic and semi-synthetic strategies to study ubiquitin signaling

artículo científico publicado en 2016

Synthetic ubiquitinated proteins meet the proteasome: Distinct roles of ubiquitin in a chain

scientific article published on 29 March 2019

Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements.

artículo científico publicado en 2013

Technologies for MHC class I immunoproteomics

artículo científico publicado en 2010

The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K

scientific article published on 14 February 2019

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

artículo científico publicado en 2011

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

scientific article published on 13 July 2016

The deubiquitinating enzyme UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel

artículo científico publicado en 2007

The first step of peptide selection in antigen presentation by MHC class I molecules

artículo científico publicado en 2015

Tools to investigate the ubiquitin proteasome system

artículo científico publicado en 2017

Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific Proteases

artículo científico publicado en 2018

Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties

artículo científico publicado en 2019

Transpeptidation and reverse proteolysis and their consequences for immunity

artículo científico publicado en 2008

Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.

artículo científico

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

scientific journal article

Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2

scientific journal article

USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7

scientific article published on 29 March 2019

USP7: combining tools towards selectivity

scientific article published on 01 April 2019

UV-induced ligand exchange in MHC class I protein crystals

artículo científico publicado en 2009

Ubi-tagging: A ubiquitin-based modular platform for site-directed antibody conjugation

scholarly article

Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response

artículo científico publicado en 2020

Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly

scientific article published on 03 February 2021

Ubiquitin proteasome system as a pharmacological target in neurodegeneration.

artículo científico publicado en 2006

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

artículo científico publicado en 2012

Ubiquitin‐Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes

artículo científico publicado el 25 de septiembre de 2012

Unnatural amino acid incorporation in E. coli: current and future applications in the design of therapeutic proteins

artículo científico

Visualizing Proteasome Activity and Intracellular Localization Using Fluorescent Proteins and Activity-Based Probes

scientific article published on 20 August 2019

Why do proteases mess up with antigen presentation by re-shuffling antigen sequences?

artículo científico publicado en 2018

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

artículo científico publicado en 2004