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Lista de obras de Shahriar Mobashery

715. Bulgecin A lowers Imipenem MICs in Clinical MDR Acinetobacter baumannii (ACB) Strains

A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis

artículo científico publicado en 2001

A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli

scholarly article by David A Dik et al published 26 September 2018 in Biochemistry

A Type VI secretion system delivers a cell-wall amidase to target bacterial competitors

scientific article published on 12 April 2020

A chemical biological strategy to facilitate diabetic wound healing.

artículo científico publicado en 2013

A computational evaluation of the mechanism of penicillin-binding protein-catalyzed cross-linking of the bacterial cell wall

artículo científico publicado en 2011

A convenient synthesis of a selective gelatinase inhibitor as an antimetastatic agent

artículo científico publicado en 2004

A dynamic structure for the acyl-enzyme species of the antibiotic aztreonam with the Citrobacter freundii beta-lactamase revealed by infrared spectroscopy and molecular dynamics simulations

artículo científico publicado en 2003

A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.

artículo científico publicado en 2005

A mechanism-based inhibitor targeting the DD-transpeptidase activity of bacterial penicillin-binding proteins.

artículo científico publicado en 2003

A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin.

artículo científico publicado en 2004

A positive positive to negative

scientific article published on 01 October 2018

A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition

artículo científico publicado en 2009

A practical synthesis of nitrocefin

artículo científico publicado en 2005

AAC(3)-XI, a new aminoglycoside 3-N-acetyltransferase from Corynebacterium striatum

artículo científico publicado en 2015

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

artículo científico publicado en 2005

Acceleration of diabetic wound healing using a novel protease-anti-protease combination therapy

artículo científico publicado en 2015

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa

artículo científico publicado en 2016

Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall

artículo científico publicado en 2005

Activation of BlaR1 protein of methicillin-resistant Staphylococcus aureus, its proteolytic processing, and recovery from induction of resistance.

artículo científico publicado en 2011

Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases

artículo científico publicado en 2009

Activities of Oxadiazole Antibacterials against Staphylococcus aureus and Other Gram-Positive Bacteria

scholarly article by Sara Ceballos et al published August 2018 in Antimicrobial Agents and Chemotherapy

Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae

artículo científico publicado en 2018

Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae

artículo científico publicado en 2016

Aminoglycoside 2''-phosphotransferase type IIIa from Enterococcus.

artículo científico publicado en 2008

Aminoglycosides modified by resistance enzymes display diminished binding to the bacterial ribosomal aminoacyl-tRNA site

artículo científico publicado en 2002

Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance

artículo científico publicado en 2000

An Amino Acid Position at Crossroads of Evolution of Protein Function: ANTIBIOTIC SENSOR DOMAIN OF BlaR1 PROTEIN FROM STAPHYLOCOCCUS AUREUS VERSUS CLASS D  -LACTAMASES

artículo científico publicado en 2012

An Antibiotic-Resistance Enzyme from a Deep-Sea Bacterium

artículo científico publicado en 2010

Antibiotics as physiological stress inducers and bacterial response to the challenge

artículo científico publicado en 2012

Antimetastatic activity of a novel mechanism-based gelatinase inhibitor

artículo científico publicado en 2005

Bacterial AmpD at the crossroads of peptidoglycan recycling and manifestation of antibiotic resistance

artículo científico publicado en 2009

Bacterial cell-wall recycling.

artículo científico publicado en 2012

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

artículo científico publicado en 2005

Binding of the gene repressor BlaI to the bla operon in methicillin-resistant Staphylococcus aureus.

artículo científico publicado en 2010

Catalytic Cycle of Glycoside Hydrolase BglX from Pseudomonas aeruginosa and Its Implications for Biofilm Formation

artículo científico publicado en 2020

Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.

artículo científico publicado en 2017

Catalytic mechanism of penicillin-binding protein 5 of Escherichia coli

artículo científico publicado en 2007

Catalytic spectrum of the penicillin-binding protein 4 of Pseudomonas aeruginosa, a nexus for the induction of β-lactam antibiotic resistance

scientific journal article

Cell surface association of matrix metalloproteinase-9 (gelatinase B).

artículo científico publicado en 2003

Cell-Wall Recycling of the Gram-Negative Bacteria and the Nexus to Antibiotic Resistance

scientific article published on 30 May 2018

Cell-Wall Remodeling by the Zinc-Protease AmpDh3 from Pseudomonas aeruginosa

artículo científico publicado en 2013

Characterization of the Dimerization Interface of Membrane Type 4 (MT4)-Matrix Metalloproteinase ⬇️

artículo científico publicado el 2 de agosto de 2011

Characterization of the beta-lactam antibiotic sensor domain of the MecR1 signal sensor/transducer protein from methicillin-resistant Staphylococcus aureus.

artículo científico publicado en 2007

Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescens

artículo científico publicado en 2006

Cinnamonitrile Adjuvants Restore Susceptibility to β-Lactams against Methicillin-Resistant Staphylococcus aureus

scientific article published on 01 July 2019

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

artículo científico publicado en 2005

Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics

artículo científico publicado en 2008

Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme

artículo científico publicado en 2002

Complications from dual roles of sodium hydride as a base and as a reducing agent

artículo científico publicado en 2009

Computational investigation of irreversible inactivation of the zinc-dependent protease carboxypeptidase A

artículo científico publicado en 2005

Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis.

artículo científico publicado en 2017

Conformational analyses of thiirane-based gelatinase inhibitors

artículo científico publicado en 2007

Conformational transition in the aminoacyl t-RNA site of the bacterial ribosome both in the presence and absence of an aminoglycoside antibiotic

scientific article published on 01 May 2007

Constructing and deconstructing the bacterial cell wall

scientific article published on 20 November 2019

Corrigendum: Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance.

artículo científico publicado en 2016

Critical involvement of a carbamylated lysine in catalytic function of class D  -lactamases

artículo científico publicado en 2001

Crystal Structures of Bacterial Peptidoglycan Amidase AmpD and an Unprecedented Activation Mechanism

artículo científico publicado en 2011

Crystal Structures of Penicillin-Binding Protein 6 from Escherichia coli

artículo científico publicado en 2009

Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae

artículo científico publicado en 2009

Crystal structure of CbpF, a bifunctional choline-binding protein and autolysis regulator from Streptococcus pneumoniae

artículo científico publicado en 2009

Crystallization and preliminary X-ray diffraction analysis of the lytic transglycosylase MltE fromEscherichia coli ⬇️

artículo científico publicado el 24 de diciembre de 2010

Cytoplasmic-membrane anchoring of a class A beta-lactamase and its capacity in manifesting antibiotic resistance

artículo científico publicado en 2007

DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2.

artículo científico publicado en 2009

Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Walls

artículo científico publicado en 2017

Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples

artículo científico publicado en 2006

Design and synthesis of a structurally constrained aminoglycoside

artículo científico publicado en 2007

Design of novel antibiotics that bind to the ribosomal acyltransfer site

artículo científico publicado en 2002

Design, synthesis, and characterization of potent, slow-binding inhibitors that are selective for gelatinases

artículo científico publicado en 2002

Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A.

artículo científico publicado en 2005

Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

artículo científico publicado en 2013

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

artículo científico publicado en 2017

Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.

artículo científico publicado en 2014

Discovery of a potent picolinamide antibacterial active against Clostridioides difficile

artículo científico publicado en 2020

Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

artículo científico publicado en 2015

Discrete steps in sensing of beta-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium

artículo científico publicado en 2006

Disruption of Allosteric Response as an Unprecedented Mechanism of Resistance to Antibiotics

artículo científico publicado en 2014

Dissection of events in the resistance to β-lactam antibiotics mediated by the protein BlaR1 from Staphylococcus aureus.

artículo científico publicado en 2012

Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice.

artículo científico publicado en 2018

Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background

artículo científico publicado en 2008

Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood-brain barrier opening in rodents: Differences in response based on strains and solvents

artículo científico publicado en 2006

Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1

artículo científico publicado en 2007

Elucidation of the structure of the membrane anchor of penicillin-binding protein 5 of Escherichia coli

artículo científico publicado en 2010

Enantiomers of a selective gelatinase inhibitor: (R)- and (S)-2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane

scientific article published on 04 October 2014

Endless Resistance. Endless Antibiotics?

artículo científico publicado en 2016

Endogenous matrix metalloproteinases 2 and 9 regulate activation of CD4+ and CD8+ T cells

artículo científico publicado en 2010

Enzymology of Bacterial Resistance

article

Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa.

artículo científico publicado en 2018

Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases

artículo científico publicado en 2017

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

artículo científico publicado en 2010

Exploration of the Structural Space in 4(3H)-Quinazolinone Antibacterials

scientific article published on 28 April 2020

Exploration of the structure-activity relationship of 1,2,4-oxadiazole antibiotics

artículo científico publicado en 2015

Exploring the functional space of thiiranes as gelatinase inhibitors using click chemistry

scientific article published on 27 February 2011

Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers

scientific article published on 19 July 2018

Extracellular proteases as targets for treatment of cancer metastases

artículo científico publicado en 2004

Facile preparation of a highly functionalized tetrahydropyran by catalytic hydrogenation of an oxazoline

artículo científico publicado en 2008

Fluorescence Assessment of the AmpR-Signaling Network of Pseudomonas aeruginosa to Exposure to β-Lactam Antibiotics

scientific article published on 10 February 2020

Fluorinated aminoglycosides and their mechanistic implication for aminoglycoside 3'-phosphotransferases from Gram-negative bacteria

artículo científico publicado en 2004

From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa

artículo científico publicado en 2017

Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1).

artículo científico publicado en 2014

High-Resolution Crystal Structure of MltE, an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase from Escherichia coli

artículo científico publicado en 2011

High-resolution X-ray structure of an acyl-enzyme species for the class D OXA-10 beta-lactamase

artículo científico publicado en 2002

Host-guest chemistry of the peptidoglycan

artículo científico publicado en 2010

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

artículo científico publicado en 2013

Hydrolysis of ATP by aminoglycoside 3'-phosphotransferases: an unexpected cost to bacteria for harboring an antibiotic resistance enzyme

artículo científico publicado en 2006

Hyperbaric oxygen therapy accelerates wound healing in diabetic mice by decreasing active matrix metalloproteinase-9

scientific article published on 03 December 2019

Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)

artículo científico publicado en 2008

Identification of Products of Inhibition of GES-2 β-Lactamase by Tazobactam by X-ray Crystallography and Spectrometry ⬇️

artículo científico publicado el 22 de febrero de 2011

In Search of Selectivity in Inhibition of ADAM10

artículo científico publicado en 2018

In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams

artículo científico publicado en 2016

Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.

artículo científico publicado en 2012

Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor

scientific article published on 01 June 2006

Inhibitors for Bacterial Cell-Wall Recycling

artículo científico publicado en 2012

Insertion of epicatechin gallate into the cytoplasmic membrane of methicillin-resistant Staphylococcus aureus disrupts penicillin-binding protein (PBP) 2a-mediated beta-lactam resistance by delocalizing PBP2.

artículo científico

Insights into class D beta-lactamases are revealed by the crystal structure of the OXA10 enzyme from Pseudomonas aeruginosa

artículo científico publicado en 2000

Insights into pneumococcal fratricide from the crystal structures of the modular killing factor LytC

artículo científico publicado en 2010

Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site

artículo científico publicado en 2006

Investigation of signal transduction routes within the sensor/transducer protein BlaR1 of Staphylococcus aureus

artículo científico publicado en 2015

Investigation of the mechanism of the cell wall DD-carboxypeptidase reaction of penicillin-binding protein 5 of Escherichia coli by quantum mechanics/molecular mechanics calculations.

artículo científico publicado en 2008

Key side products due to reactivity of dimethylmaleoyl moiety as amine protective group

scientific article published on 25 August 2009

Kinetic mechanism of enterococcal aminoglycoside phosphotransferase 2"-Ib

artículo científico publicado en 2007

Lysine N(zeta)-decarboxylation in the BlaR1 protein from Staphylococcus aureus at the root of its function as an antibiotic sensor

artículo científico publicado en 2007

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

artículo científico publicado el 20 de julio de 2011

Lysine carboxylation in proteins: OXA-10 beta-lactamase

artículo científico publicado en 2005

Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall

artículo científico publicado en 2008

Lytic transglycosylases LtgA and LtgD perform distinct roles in remodeling, recycling and releasing peptidoglycan in Neisseria gonorrhoeae

artículo científico publicado en 2016

Lytic transglycosylases: concinnity in concision of the bacterial cell wall

artículo científico publicado en 2017

MMP-9 inhibitors impair learning in spontaneously hypertensive rats

scientific article published in PLoS ONE

MT1-MMP shedding involves an ADAM and is independent of its localization in lipid rafts

artículo científico publicado en 2006

Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.

artículo científico publicado en 2010

Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.

artículo científico publicado en 2009

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram‐negative bacterial outer membrane ⬇️

artículo científico publicado el 30 de septiembre de 2011

Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly.

artículo científico publicado en 2018

Mechanism-based profiling of MMPs.

artículo científico publicado en 2010

Mechanisms Complex biological processes and their central chemical events

artículo científico publicado en 2003

Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus

artículo científico publicado en 2006

Mechanistic basis for the emergence of catalytic competence against carbapenem antibiotics by the GES family of beta-lactamases

artículo científico publicado en 2009

Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6')-Ib' from Pseudomonas aeruginosa

artículo científico publicado en 2007

Messenger functions of the bacterial cell wall-derived muropeptides

artículo científico publicado en 2012

Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor

artículo científico publicado en 2008

Metabolism of a highly selective gelatinase inhibitor generates active metabolite

artículo científico publicado en 2007

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

artículo científico publicado en 2009

Molecular dynamics at the root of expansion of function in the M69L inhibitor-resistant TEM beta-lactamase from Escherichia coli

artículo científico publicado en 2002

Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma.

artículo científico publicado en 2007

Muropeptide Binding and the X-ray Structure of the Effector Domain of the Transcriptional Regulator AmpR of Pseudomonas aeruginosa

artículo científico publicado en 2017

Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance

artículo científico publicado en 2016

Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing

artículo científico publicado en 2005

Mutational replacement of Leu-293 in the class C Enterobacter cloacae P99 beta-lactamase confers increased MIC of cefepime

artículo científico publicado en 2002

Mutations in mmpL and in the cell wall stress stimulon contribute to resistance to oxadiazole antibiotics in methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2014

N-Glycosylation pattern of the zymogenic form of human matrix metalloproteinase-9.

artículo científico publicado en 2002

O-phenyl carbamate and phenyl urea thiiranes as selective matrix metalloproteinase-2 inhibitors that cross the blood-brain barrier

scientific article published on 08 October 2013

Orthologous and Paralogous AmpD Peptidoglycan Amidases from Gram-Negative Bacteria.

artículo científico publicado en 2016

Penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.

artículo científico publicado en 2014

Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni

artículo científico publicado en 2020

Pharmacological stabilization of intracranial aneurysms in mice: a feasibility study

artículo científico publicado en 2012

Phosphoryl transfer by aminoglycoside 3'-phosphotransferases and manifestation of antibiotic resistance

artículo científico publicado en 2004

Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules

artículo científico publicado en 2015

Potent mechanism-based inhibitors for matrix metalloproteinases

artículo científico publicado en 2005

Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives

artículo científico publicado en 2018

Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity

artículo científico publicado en 2004

Prospects of therapies targeting resistant bacteria-New challenges 20 years post emergence of vancomycin-resistant enterococcus

artículo científico publicado en 2007

Prostate cancer-associated membrane type 1-matrix metalloproteinase: a pivotal role in bone response and intraosseous tumor growth.

artículo científico publicado en 2007

Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.

artículo científico publicado en 2014

QM/MM Studies of the Matrix Metalloproteinase 2 (MMP2) Inhibition Mechanism of (S)-SB-3CT and its Oxirane Analogue ⬇️

artículo científico publicado el 9 de noviembre de 2010

Quest for selectivity in inhibition of matrix metalloproteinases

artículo científico publicado en 2004

Reaction Products and the X-ray Structure of AmpDh2, a Virulence Determinant of Pseudomonas aeruginosa

artículo científico publicado en 2013

Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall.

artículo científico publicado en 2013

Reactions of the three AmpD enzymes of Pseudomonas aeruginosa

scientific journal article

Recent advances in MMP inhibitor design

artículo científico publicado en 2006

Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae

artículo científico publicado en 2010

Regioselective Control of the SNAr Amination of 5-Substituted-2,4-Dichloropyrimidines Using Tertiary Amine Nucleophiles

artículo científico publicado en 2015

Regiospecific syntheses of 6alpha-(1R-Hydroxyoctyl)penicillanic acid and 6beta-(1R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D beta-lactamases

artículo científico publicado en 2009

Regulation of the expression of the β-lactam antibiotic-resistance determinants in methicillin-resistant Staphylococcus aureus (MRSA).

artículo científico publicado en 2014

Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus

artículo científico publicado en 2003

Resistance to the third-generation cephalosporin ceftazidime by a deacylation-deficient mutant of the TEM β-lactamase by the uncommon covalent-trapping mechanism

artículo científico publicado en 2011

Restoration of susceptibility of methicillin-resistant Staphylococcus aureus to beta-lactam antibiotics by acidic pH: role of penicillin-binding protein PBP 2a.

artículo científico publicado en 2008

Revealing cell-surface intramolecular interactions in the BlaR1 protein of methicillin-resistant Staphylococcus aureus by NMR spectroscopy

artículo científico publicado en 2013

Roles of matrix metalloproteinases in flow-induced outward vascular remodeling

artículo científico publicado en 2009

Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury.

artículo científico publicado en 2016

Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier

artículo científico publicado en 2012

Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury

artículo científico publicado en 2013

Selective water-soluble gelatinase inhibitor prodrugs.

artículo científico publicado en 2011

Shared functional attributes between the mecA gene product of Staphylococcus sciuri and penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.

artículo científico publicado en 2007

Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases

artículo científico publicado en 2013

Short Alkylated Peptoid Mimics of Antimicrobial Lipopeptides ⬇️

artículo científico publicado el 18 de octubre de 2010

Side reaction of significance in preparation of peptide- or peptidomimetic-based hydroxamate enzyme inhibitors

artículo científico publicado en 2006

Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics

scientific article published on 18 January 2019

Source of phosphate in the enzymic reaction as a point of distinction among aminoglycoside 2''-phosphotransferases.

artículo científico publicado en 2009

Strategy in inhibition of cathepsin B, a target in tumor invasion and metastasis

artículo científico publicado en 2004

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in  -Lactam Resistance

artículo científico publicado en 2013

Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

artículo científico publicado en 2013

Structural Basis for Progression toward the Carbapenemase Activity in the GES Family of β-Lactamases

artículo científico publicado en 2012

Structural Basis of the Heterodimer Formation between Cell Shape-Determining Proteins Csd1 and Csd2 from Helicobacter pylori

artículo científico publicado en 2016

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

artículo científico publicado en 2014

Structural aspects for evolution of beta-lactamases from penicillin-binding proteins

artículo científico publicado en 2003

Structural basis for potent slow binding inhibition of human matrix metalloproteinase-2 (MMP-2).

artículo científico publicado en 2003

Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape

artículo científico publicado en 2014

Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division

scientific article published on 05 December 2019

Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM beta-lactamase

artículo científico publicado en 2005

Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins

artículo científico publicado en 2007

Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

artículo científico publicado en 2014

Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase

artículo científico publicado en 2015

Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors

artículo científico publicado en 2012

Structure-Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

artículo científico publicado en 2016

Structure-Activity Relationship for the Oxadiazole Class of Antibacterials

artículo científico publicado en 2019

Structure-activity relationship for the oxadiazole class of antibiotics.

artículo científico publicado en 2015

Structure-activity relationship of the cinnamamide family of antibiotic potentiators for methicillin-resistant Staphylococcus aureus (MRSA)

scientific article published on 30 October 2018

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence

artículo científico publicado en 2015

Sulfonate-containing thiiranes as selective gelatinase inhibitors

artículo científico publicado en 2010

Sulfonylation-induced N- to O-acetyl migration in 2-acetamidoethanol derivatives

artículo científico publicado en 2010

Susceptibility of Methicillin-Resistant Staphylococcus aureus to Five Quinazolinone Antibacterials

artículo científico publicado en 2019

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA.

artículo científico publicado en 2015

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol

artículo científico publicado en 2012

Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium

artículo científico publicado en 2015

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

artículo científico publicado en 2017

Synthesis of a fragment of bacterial cell wall

artículo científico publicado en 2004

Synthesis of an inhibitor-tethered resin for detection of active matrix metalloproteinases involved in disease

scientific article published on 01 August 2006

Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl)thiiranes as selective gelatinase inhibitors

scientific article published on 01 September 2005

Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors

artículo científico publicado en 2009

Synthetic peptidoglycan motifs for germination of bacterial spores

artículo científico publicado en 2010

Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria

artículo científico publicado en 2004

Tackling antibiotic resistance

artículo científico publicado en 2011

Testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain

artículo científico publicado en 2008

The Allosteric Site for the Nascent Cell Wall in Penicillin-Binding Protein 2a: An Achilles' Heel of Methicillin-Resistant Staphylococcus aureus

artículo científico publicado en 2015

The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of L,D-Carboxypeptidase.

artículo científico publicado en 2015

The First Structural and Mechanistic Insights for Class D β-Lactamases: Evidence for a Novel Catalytic Process for Turnover of β-Lactam Antibiotics

article

The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity

artículo científico publicado en 2016

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

artículo científico publicado en 2019

The Tipper-Strominger Hypothesis and Triggering of Allostery in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus (MRSA).

artículo científico publicado en 2015

The X-Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based Inhibitor

artículo científico publicado en 2010

The basis for resistance to beta-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus

artículo científico publicado en 2004

The bifunctional enzymes of antibiotic resistance

artículo científico publicado en 2009

The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography

artículo científico publicado en 2003

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity

artículo científico publicado en 2016

The external PASTA domain of the essential serine/threonine protein kinase PknB regulates mycobacterial growth

artículo científico publicado en 2015

The future of the β-lactams.

artículo científico publicado en 2010

The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins

artículo científico publicado en 2004

The oxadiazole antibacterials

artículo científico publicado en 2016

The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa.

artículo científico publicado en 2014

Thermodynamics of interactions of vancomycin and synthetic surrogates of bacterial cell wall

artículo científico publicado en 2006

Three decades of the class A beta-lactamase acyl-enzyme.

scientific article published on October 2009

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials

artículo científico publicado en 2015

Three-dimensional structure of the bacterial cell wall peptidoglycan

artículo científico publicado en 2006

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics.

artículo científico publicado en 2018

Total synthesis of N-acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and evaluation of its turnover by AmpD from Escherichia coli

artículo científico publicado en 2009

Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.

artículo científico publicado en 2017

Turnover Chemistry and Structural Characterization of the Cj0843c Lytic Transglycosylase of <i>Campylobacter jejuni</i>

artículo científico publicado en 2021

Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa

artículo científico publicado en 2016

Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa

artículo científico publicado en 2016

Use of silver carbonate in the Wittig reaction

artículo científico publicado en 2013

Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing

scientific article published on 27 September 2018

Versatility of aminoglycosides and prospects for their future

artículo científico publicado en 2003

Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury

artículo científico publicado en 2015

Whole-Genome Shotgun Sequencing of Two β-Proteobacterial Species in Search of the Bulgecin Biosynthetic Cluster.

artículo científico publicado en 2017

Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta-lactamase: Raman crystallographic evidence

artículo científico publicado en 2008

X-ray Structure of Catenated Lytic Transglycosylase SltB1.

artículo científico publicado en 2017

X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction

artículo científico publicado en 2004

X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid

artículo científico publicado en 1999

β-Lactam Resistance Mechanisms: Gram-Positive Bacteria and Mycobacterium tuberculosis

artículo científico publicado en 2016

β-Lactams against the Fortress of the Gram-Positive <i>Staphylococcus aureus</i> Bacterium

artículo científico publicado en 2020

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