Lista de obras - Lara M. Mangravite - Dominio Público Uruguay

A community approach to mortality prediction in sepsis via gene expression analysis.

artículo científico publicado en 2018

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

artículo científico publicado en 2018

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

artículo científico publicado en 2012

A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research

artículo científico publicado en 2018

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease

artículo científico publicado en 2020

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

artículo científico publicado en 2013

An Open Toolkit for Tracking Open Science Partnership Implementation and Impact

An open toolkit for tracking open science partnership implementation and impact

artículo científico publicado en 2019

An open toolkit for tracking open science partnership implementation and impact.

artículo científico publicado en 2019

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

artículo científico publicado en 2020

Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source

artículo científico publicado en 2011

Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

artículo científico publicado en 2001

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin

artículo científico publicado en 2010

Correction: RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

artículo científico publicado en 2016

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

artículo científico publicado en 2016

Crowdsourcing biomedical research: leveraging communities as innovation engines

artículo científico publicado en 2016

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

artículo científico publicado en 2013

Data Science Approaches for Effective Use of Mobile Device-Based Collection of Real-World Data

artículo científico publicado en 2020

Democratizing Health Data for Translational Research

artículo científico publicado en 2018

Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD)

artículo científico publicado en 2020

Detecting the impact of subject characteristics on machine learning-based diagnostic applications

scientific article published on 11 October 2019

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling

Developing predictive molecular maps of human disease through community-based modeling

artículo científico publicado en 2012

Differential Iron(II) Affinity of the Sites of the Diiron Cluster in Protein R2 of Escherichia coli Ribonucleotide Reductase: Tracking the Individual Sites through the O2 Activation Sequence

scientific article published in 1997

Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men

artículo científico publicado en 2012

Electron Injection through a Specific Pathway Determines the Outcome of Oxygen Activation at the Diiron Cluster in the F208Y Mutant ofEscherichia coliRibonucleotide Reductase Protein R2†

scientific article published on 01 January 1998

Engaging a community to enable disease-centric data sharing with the NF Data Portal

scientific article published on 13 December 2019

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

artículo científico publicado en 2016

Erratum: Prediction of human population responses to toxic compounds by a collaborative competition

article

Evaluating the Utility of Smartphone-Based Sensor Assessments in Persons With Multiple Sclerosis in the Real-World Using an App (elevateMS): Observational, Prospective Pilot Digital Health Study

artículo científico publicado en 2020

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1 ⬇️

artículo científico publicado el 28 de abril de 2003

Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response

artículo científico publicado en 2007

Formative Evaluation of Participant Experience With Mobile eConsent in the App-Mediated Parkinson mPower Study: A Mixed Methods Study.

artículo científico publicado en 2017

Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations

artículo científico publicado en 2004

Functional dissection of Alzheimer's disease brain gene expression signatures in humans and mouse models

article

Gene expression elucidates functional impact of polygenic risk for schizophrenia

artículo científico publicado en 2016

Genome-wide association of lipid-lowering response to statins in combined study populations

artículo científico publicado en 2010

HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism

artículo científico publicado en 2013

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

artículo científico publicado en 2016

Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation

scientific article published on 01 July 2019

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

artículo científico publicado en 2021

Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants

scientific article published on 17 February 2020

Informed Consent in Two Alzheimer's Disease Research Centers: Insights From Research Coordinators

scientific article published on 16 March 2020

Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs

artículo científico publicado en 2013

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

scientific article published on 12 October 2020

Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells

artículo científico publicado en 2003

Mangravite et al. reply

artículo científico publicado en 2014

Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

scientific article published on 01 July 2020

Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

Molecular estimation of neurodegeneration pseudotime in older brains

artículo científico publicado en 2020

Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney

artículo científico publicado en 2003

Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins

artículo científico publicado en 2008

PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.

artículo científico publicado en 2004

PharmGKB very important pharmacogene: SLCO1B1.

artículo científico publicado en 2010

Pharmacogenomic discovery using cell-based models

artículo científico publicado en 2009

Pharmacogenomics of statin response

artículo científico publicado en 2007

Pharmacogenomics of statin response

scientific article published on 01 December 2008

Prediction of human population responses to toxic compounds by a collaborative competition

artículo científico publicado en 2015

RHOA is a modulator of the cholesterol-lowering effects of statin

artículo científico publicado en 2012

Research Highlights

Smartphone-Based VO2max Measurement With Heart Snapshot in Clinical and Real-world Settings With a Diverse Population: Validation Study

artículo científico publicado en 2021

Sorting of rat SPNT in renal epithelium is independent of N-glycosylation

artículo científico publicado en 2003

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

artículo científico publicado en 2019

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

artículo científico publicado en 2013

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

artículo científico publicado en 2017

The AD Knowledge Portal: A Repository for Multi-Omic Data on Alzheimer's Disease and Aging

artículo científico publicado en 2020

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

artículo científico publicado en 2018

The PsychENCODE project

artículo científico publicado en 2015

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics

artículo científico publicado en 2005

Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.

artículo científico publicado en 2012

Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism

artículo científico publicado en 2014

Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.

artículo científico publicado en 2018

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment

artículo científico publicado en 2008

Lista de obras de Lara M. Mangravite

A community approach to mortality prediction in sepsis via gene expression analysis.

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research

A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

An Open Toolkit for Tracking Open Science Partnership Implementation and Impact

An open toolkit for tracking open science partnership implementation and impact

An open toolkit for tracking open science partnership implementation and impact.

Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains

Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source

Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin

Correction: RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

Crowdsourcing biomedical research: leveraging communities as innovation engines

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

Data Science Approaches for Effective Use of Mobile Device-Based Collection of Real-World Data

Democratizing Health Data for Translational Research

Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD)

Detecting the impact of subject characteristics on machine learning-based diagnostic applications

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling

Developing predictive molecular maps of human disease through community-based modeling

Differential Iron(II) Affinity of the Sites of the Diiron Cluster in Protein R2 of Escherichia coli Ribonucleotide Reductase: Tracking the Individual Sites through the O2 Activation Sequence

Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men

Electron Injection through a Specific Pathway Determines the Outcome of Oxygen Activation at the Diiron Cluster in the F208Y Mutant ofEscherichia coliRibonucleotide Reductase Protein R2†

Engaging a community to enable disease-centric data sharing with the NF Data Portal

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Erratum: Prediction of human population responses to toxic compounds by a collaborative competition

Evaluating the Utility of Smartphone-Based Sensor Assessments in Persons With Multiple Sclerosis in the Real-World Using an App (elevateMS): Observational, Prospective Pilot Digital Health Study

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1 ⬇️

Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response

Formative Evaluation of Participant Experience With Mobile eConsent in the App-Mediated Parkinson mPower Study: A Mixed Methods Study.

Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations

Functional dissection of Alzheimer's disease brain gene expression signatures in humans and mouse models

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Genome-wide association of lipid-lowering response to statins in combined study populations

HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants

Informed Consent in Two Alzheimer's Disease Research Centers: Insights From Research Coordinators

Integrative modeling of eQTLs and cis-regulatory elements suggests mechanisms underlying cell type specificity of eQTLs

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells

Mangravite et al. reply

Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach

Molecular estimation of neurodegeneration pseudotime in older brains

Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney

Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins

PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.

PharmGKB very important pharmacogene: SLCO1B1.

Pharmacogenomic discovery using cell-based models

Pharmacogenomics of statin response

Pharmacogenomics of statin response

Prediction of human population responses to toxic compounds by a collaborative competition

RHOA is a modulator of the cholesterol-lowering effects of statin

Research Highlights

Smartphone-Based VO2max Measurement With Heart Snapshot in Clinical and Real-world Settings With a Diverse Population: Validation Study

Sorting of rat SPNT in renal epithelium is independent of N-glycosylation

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

The AD Knowledge Portal: A Repository for Multi-Omic Data on Alzheimer's Disease and Aging

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease

The PsychENCODE project

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics

Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.

Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism

Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment