Lista de obras - John Cambier - Dominio Público Uruguay

A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation

scientific article published on 10 May 2019

A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels

artículo científico publicado en 2014

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

artículo científico publicado en 2011

A human CD4 monoclonal antibody for the treatment of T-cell lymphoma combines inhibition of T-cell signaling by a dual mechanism with potent Fc-dependent effector activity

artículo científico publicado en 2007

A rapid method for the purification of immunoglobulin M (IgM) from the sera of certain mammalian species

artículo científico publicado en 1974

Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging.

artículo científico publicado en 2008

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

artículo científico publicado en 2001

Aging and immune function. Summary of a workshop held at Trudeau Institute, Saranac Lake, NY

artículo científico publicado en 2005

Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.

scientific article published on 17 January 2014

Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes.

artículo científico publicado en 1995

Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

artículo científico publicado en 1998

Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production

artículo científico publicado en 2014

Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.

artículo científico publicado en 2013

Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death.

artículo científico publicado en 2004

B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses

article

B cell antigen receptor signaling 101.

artículo científico publicado en 2004

B cell antigen receptor signaling: roles in cell development and disease.

artículo científico publicado en 2002

B cell development: signal transduction by antigen receptors and their surrogates.

artículo científico publicado en 1999

B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens

artículo científico publicado en 2015

B cell receptor signaling in human systemic lupus erythematosus.

artículo científico publicado en 2006

B cells and type 1 diabetes ...in mice and men.

artículo científico publicado en 2014

B cells talk to their progenitors

artículo científico publicado en 2011

B lymphocyte activation during cognate interactions with CD4+ T lymphocytes: molecular dynamics and immunologic consequences.

artículo científico publicado en 2003

B lymphocyte antigen receptor signaling: initiation, amplification, and regulation

artículo científico publicado en 2013

Bacterial superantigens induce V beta-specific T cell receptor internalization

scientific article published on 01 July 1996

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

artículo científico publicado en 1987

CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase

artículo científico publicado en 1998

COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.

scientific article published on March 2013

Capturing antigen receptor components

artículo científico publicado en 1991

Cellular reactive oxygen species inhibit MPYS induction of IFNβ

artículo científico publicado en 2010

Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes

artículo científico publicado en 2009

Co-receptor and accessory regulation of B-cell antigen receptor signal transduction.

artículo científico publicado en 1997

Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines

artículo científico publicado en 2016

Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome

scientific article published on 06 September 2013

Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction.

artículo científico publicado en 2000

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

artículo científico publicado en 1998

Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude

artículo científico publicado en 2011

Differential binding activity of ARH1/TAM motifs

scientific article published on 01 January 1995

Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells.

artículo científico publicado en 1999

Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells

artículo científico publicado en 2009

Establishing anergy as a bona fide in vivo mechanism of B cell tolerance.

artículo científico publicado en 2009

Evaluation of methods for the isolation of plasma membranes displaying guanosine 5'-triphosphate-dependence for the regulation of adenylate cyclase activity: potential application to the study of other guanosine 5'-triphosphate-dependent transductio

artículo científico publicado en 1988

Fc gamma RIIB as a potential molecular target for intravenous gamma globulin therapy.

artículo científico publicado en 2001

Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation

artículo científico publicado en 1997

FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation.

artículo científico publicado en 2008

General parity between trio and pairwise breeding of laboratory mice in static caging

artículo científico publicado en 2014

Hyper-Ia antigen expression on B cells from B6-lpr/lpr mice correlates with manifestations of the autoimmune state

artículo científico publicado en 1985

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

artículo científico publicado en 2012

Identification of anergic B cells within a wild-type repertoire.

artículo científico publicado en 2006

Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.

artículo científico publicado en 2015

Immune senescence. Editorial overview

scientific article published on 23 July 2011

Immunosenescence: a problem of lymphopoiesis, homeostasis, microenvironment, and signaling

artículo científico publicado en 2005

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.

artículo científico publicado en 2017

Inhibitory receptors abound?

artículo científico publicado en 1997

Integrated immunology in Colorado.

artículo científico publicado en 2013

Interleukin-4 overcomes the negative influence of cyclic AMP accumulation on antigen receptor stimulated B lymphocytes

artículo científico publicado en 1998

Introduction: multifaceted roles of lipids and their catabolites in immune cell signaling.

artículo científico publicado en 2002

Involvement of CD4 D3-D4 membrane proximal extracellular domain for the inhibitory effect of oxidative stress on activation-induced CD4 down-regulation and its possible role for T cell activation.

artículo científico publicado en 2003

Ligation of human CD4 interferes with antigen-induced activation of primary T cells

artículo científico publicado en 2002

MHC class II structural requirements for the association with Igalpha/beta, and signaling of calcium mobilization and cell death

artículo científico publicado en 2007

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

artículo científico publicado en 2011

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

scientific article published on 02 October 2005

Manipulation of B cell antigen receptor tyrosine phosphorylation using aluminum fluoride and sodium orthovanadate.

artículo científico publicado en 1995

Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.

artículo científico publicado en 2003

Modulation of MHC class II signal transduction by CD19

scientific article published on 01 January 2007

Modulation of in vitro murine B-lymphocyte response by curcumin

artículo científico publicado en 2009

Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

artículo científico publicado en 2000

Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling.

artículo científico publicado en 2015

Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells

artículo científico publicado en 2013

Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase

artículo científico publicado en 2000

Promotion of B cell immune responses via an alum-induced myeloid cell population

artículo científico publicado en 2004

Qualitative Regulation of B Cell Antigen Receptor Signaling by CD19: Selective Requirement for PI3-Kinase Activation, Inositol-1,4,5-Trisphosphate Production and Ca2+ Mobilization ⬇️

artículo científico publicado el 1 de diciembre de 1997

Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck.

artículo científico publicado en 2004

Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors.

artículo científico publicado en 2008

Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infection

artículo científico publicado en 2012

Role of B lymphocytes in the pathogenesis of type 1 diabetes.

artículo científico publicado en 2014

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

artículo científico publicado en 1995

SMIP-016 in action: CD37 as a death receptor

artículo científico publicado en 2012

STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.

artículo científico publicado en 2013

Seeing the way to B-cell growth

scientific article published on 01 February 1986

Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation

article

Signal transduction by T- and B-cell antigen receptors: converging structures and concepts

artículo científico publicado el 1 de junio de 1992

Silencing of autoreactive B cells by anergy: a fresh perspective.

artículo científico publicado en 2006

Sorting of B lymphoblasts based upon cell diameter provides cell populations enriched in different stages of cell cycle

scientific article published on 01 September 1983

Structural compartmentalization of MHC class II signaling function.

artículo científico publicado en 1993

T-cell development and transmembrane signaling: changing biological responses through an unchanging receptor ⬇️

artículo científico publicado el 1 de febrero de 1991

TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.

artículo científico publicado en 2001

Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy

article

The B-cell antigen receptor complex: structure and signal transduction

artículo científico publicado en 1994

The SHIP phosphatase becomes associated with Fc gammaRIIB1 and is tyrosine phosphorylated during 'negative' signaling

artículo científico publicado en 1996

The biochemical basis of transmembrane signalling by B lymphocyte surface immunoglobulin

artículo científico publicado en 1985

The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans.

artículo científico publicado en 2018

The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms.

artículo científico publicado en 2010

The inositol 5-phosphatase SHIP-1 and adaptors Dok-1 and 2 play central roles in CD4-mediated inhibitory signaling.

artículo científico publicado en 2012

The major histocompatibility complex-restricted antigen receptor on T cells: Distribution on thymus and peripheral T cells

article

The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.

artículo científico publicado en 1989

Two distinct tyrosine-based motifs enable the inhibitory receptor FcgammaRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap

artículo científico publicado en 2004

Unique features of SHIP, SHP-1 and SHP-2 binding to FcgammaRIIb revealed by surface plasmon resonance analysis

artículo científico publicado en 1999

αβ TCR⁺ T cells, but not B cells, promote autoimmune keratitis in b10 mice lacking γδ T cells

artículo científico publicado en 2012

γδ T cells affect IL-4 production and B-cell tolerance

artículo científico publicado en 2014

Lista de obras de John Cambier

A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation

A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

A human CD4 monoclonal antibody for the treatment of T-cell lymphoma combines inhibition of T-cell signaling by a dual mechanism with potent Fc-dependent effector activity

A rapid method for the purification of immunoglobulin M (IgM) from the sera of certain mammalian species

Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging.

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

Aging and immune function. Summary of a workshop held at Trudeau Institute, Saranac Lake, NY

Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.

Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes.

Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.

Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production

Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.

Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death.

B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses

B cell antigen receptor signaling 101.

B cell antigen receptor signaling: roles in cell development and disease.

B cell development: signal transduction by antigen receptors and their surrogates.

B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens

B cell receptor signaling in human systemic lupus erythematosus.

B cells and type 1 diabetes ...in mice and men.

B cells talk to their progenitors

B lymphocyte activation during cognate interactions with CD4+ T lymphocytes: molecular dynamics and immunologic consequences.

B lymphocyte antigen receptor signaling: initiation, amplification, and regulation

Bacterial superantigens induce V beta-specific T cell receptor internalization

Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking

CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase

COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.

Capturing antigen receptor components

Cellular reactive oxygen species inhibit MPYS induction of IFNβ

Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes

Co-receptor and accessory regulation of B-cell antigen receptor signal transduction.

Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines

Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome

Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction.

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

Differential STIM1 expression in T and B cell subsets suggests a role in determining antigen receptor signal amplitude

Differential binding activity of ARH1/TAM motifs

Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells.

Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells

Establishing anergy as a bona fide in vivo mechanism of B cell tolerance.

Evaluation of methods for the isolation of plasma membranes displaying guanosine 5'-triphosphate-dependence for the regulation of adenylate cyclase activity: potential application to the study of other guanosine 5'-triphosphate-dependent transductio

Fc gamma RIIB as a potential molecular target for intravenous gamma globulin therapy.

Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation

FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation.

General parity between trio and pairwise breeding of laboratory mice in static caging

Hyper-Ia antigen expression on B cells from B6-lpr/lpr mice correlates with manifestations of the autoimmune state

Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

Identification of anergic B cells within a wild-type repertoire.

Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.

Immune senescence. Editorial overview

Immunosenescence: a problem of lymphopoiesis, homeostasis, microenvironment, and signaling

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway.

Inhibitory receptors abound?

Integrated immunology in Colorado.

Interleukin-4 overcomes the negative influence of cyclic AMP accumulation on antigen receptor stimulated B lymphocytes

Introduction: multifaceted roles of lipids and their catabolites in immune cell signaling.

Involvement of CD4 D3-D4 membrane proximal extracellular domain for the inhibitory effect of oxidative stress on activation-induced CD4 down-regulation and its possible role for T cell activation.

Ligation of human CD4 interferes with antigen-induced activation of primary T cells

MHC class II structural requirements for the association with Igalpha/beta, and signaling of calcium mobilization and cell death

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

Manipulation of B cell antigen receptor tyrosine phosphorylation using aluminum fluoride and sodium orthovanadate.

Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.

Modulation of MHC class II signal transduction by CD19

Modulation of in vitro murine B-lymphocyte response by curcumin

Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils

Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling.

Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells

Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase

Promotion of B cell immune responses via an alum-induced myeloid cell population

Qualitative Regulation of B Cell Antigen Receptor Signaling by CD19: Selective Requirement for PI3-Kinase Activation, Inositol-1,4,5-Trisphosphate Production and Ca2+ Mobilization ⬇️

Regulation of BCR signal transduction in B-1 cells requires the expression of the Src family kinase Lck.

Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors.

Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infection

Role of B lymphocytes in the pathogenesis of type 1 diabetes.

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

SMIP-016 in action: CD37 as a death receptor

STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.