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Lista de obras de Jack Satsangi

A plea for TDM-based optimisation for treatment of Crohn's disease - Authors' reply

artículo científico publicado en 2017

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

scholarly article published 27 September 2017

A role for vimentin in Crohn disease

artículo científico publicado en 2012

Advances in IBD genetics

artículo científico

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis

article

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways

artículo científico publicado en 2008

Association of DLG5 and inflammatory bowel disease across populations

artículo científico publicado en 2006

Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection

artículo científico publicado en 2003

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

artículo científico publicado en 2007

Autologous Haematopoietic Stem Cell Transplantation for Crohn's Disease: A Retrospective Survey of Long-term Outcomes From the European Society for Blood and Marrow Transplantation

artículo científico publicado en 2018

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial

artículo científico

Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study.

artículo científico publicado en 2019

Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial

artículo científico publicado en 2017

Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety

artículo científico publicado en 2003

Barrett's esophagus: evolutionary insights from genomics

artículo científico publicado en 2013

Bayesian refinement of association signals for 14 loci in 3 common diseases

artículo científico publicado en 2012

Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics.

scientific article published on 08 June 2013

Biomarkers in Search of Precision Medicine in IBD.

artículo científico publicado en 2016

Blood-based DNA methylation in Crohn's disease and severity of intestinal inflammation

artículo científico publicado en 2019

COVID-19 and Gastrointestinal Disease. Implications for the Gastroenterologist

artículo científico publicado en 2020

Can Thiopurines Prevent Formation of Antibodies Against Tumor Necrosis Factor Antagonists After Failure of These Therapies?

scientific article published on 05 October 2016

Changes to serum sample tube and processing methodology does not cause Intra-Individual [corrected] variation in automated whole serum N-glycan profiling in health and disease

artículo científico publicado en 2015

Characterisation of osteoprotegerin autoantibodies in coeliac disease

artículo científico

Characterization of intestinal gene expression profiles in Crohn's disease by genome-wide microarray analysis.

artículo científico publicado en 2010

Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells

artículo científico publicado en 2011

Clinical utility and diagnostic accuracy of faecal calprotectin for IBD at first presentation to gastroenterology services in adults aged 16-50 years

artículo científico publicado en 2015

Common variants at five new loci associated with early-onset inflammatory bowel disease

artículo científico publicado en 2009

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

artículo científico publicado en 2010

Contribution of CARD15 variants in determining susceptibility to Crohn's disease in Sweden

artículo científico publicado en 2006

Contribution of the IBD5 locus to Crohn's disease in the Swedish population

scientific article published on 01 February 2007

Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease

artículo científico publicado en 2016

Correction: changes to serum sample tube and processing methodology does not cause inter-individual variation in automated whole serum N-glycan profiling in health and disease

artículo científico publicado en 2015

Crohn's disease

scientific article published on 19 November 2014

Cyclooxygenase-2 (COX-2) polymorphisms and risk of inflammatory bowel disease in a Scottish and Danish case-control study

artículo científico publicado en 2010

Danish cohort of monozygotic inflammatory bowel disease twins: Clinical characteristics and inflammatory activity

artículo científico publicado en 2016

De-escalation of immunomodulator and biological therapy in inflammatory bowel disease

artículo científico publicado en 2020

De-escalation of medical therapy in inflammatory bowel disease

artículo científico publicado en 2020

Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease

artículo científico publicado en 2008

Detailed haplotype-tagging study of germline variation of MUC19 in inflammatory bowel disease.

artículo científico publicado en 2010

Disease location, anti-Saccharomyces cerevisiae antibody, and NOD2/CARD15 genotype influence the progression of disease behavior in Crohn's disease

artículo científico publicado en 2004

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

artículo científico publicado en 2009

Does cigarette smoking influence the phenotype of Crohn's disease? Analysis using the Montreal classification

artículo científico publicado en 2007

Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease?

artículo científico publicado en 2008

Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease

artículo científico publicado en 2009

Early combined immunosuppression in Crohn's disease

artículo científico publicado en 2008

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.

artículo científico publicado en 2017

Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease - associations with disease phenotype, treatment, and outcome

scholarly article by Christine Olbjørn et al published 2019 in Clinical and Experimental Gastroenterology

Fine-mapping inflammatory bowel disease loci to single-variant resolution

artículo científico publicado en 2017

Gene discovery in IBD: a decade of progress

artículo científico publicado en 2008

Genes in inflammatory bowel disease: lessons from complex diseases

artículo científico publicado en 2011

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

artículo científico publicado en 2008

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

artículo científico publicado en 2015

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis

artículo científico publicado en 2009

Genetics of childhood-onset inflammatory bowel disease

artículo científico publicado en 2011

Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history.

artículo científico publicado en 2009

Genetics of the innate immune response in inflammatory bowel disease

artículo científico publicado en 2007

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

artículo científico publicado en 2008

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

artículo científico publicado en 2017

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

article

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

artículo científico publicado en 2017

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

artículo científico publicado en 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

artículo científico publicado en 2009

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

artículo científico publicado en 2010

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway

artículo científico

Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease

artículo científico publicado en 2005

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

artículo científico publicado en 2014

Haplotype-tagging analysis of common variants of the IL23R gene demonstrates gene-wide extent of association with IBD

artículo científico publicado en 2013

Hedgehog, paneth cells, and colon cancer: a cautionary note for the use of systemic agonists/antagonists

artículo científico publicado en 2006

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

artículo científico publicado en 2012

How to Apply for and Secure EU Funding for Collaborative IBD Research Projects

artículo científico publicado en 2016

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

artículo científico publicado en 2007

Incidence of juvenile-onset Crohn's disease in Scotland: association with northern latitude and affluence

artículo científico publicado en 2004

Inflammatory Bowel Disease Through the Lens of Single-cell RNA-seq Technologies

scientific article published on 09 May 2020

Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome

artículo científico publicado en 2015

Infliximab use in Crohn's disease: impact on health care resources in the UK.

artículo científico publicado en 2005

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

artículo científico publicado en 2015

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

artículo científico publicado en 2008

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy

scientific article published on 05 July 2007

Just another flare of ulcerative colitis?

artículo científico publicado en 2020

Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D

artículo científico publicado en 2015

Letter: rationalising aminosalicylates in inflammatory bowel disease-authors' reply

scientific article published on 01 November 2020

Lymphoma Risk and Overall Safety Profile of Adalimumab in Patients With Crohn's Disease With up to 6 Years of Follow-Up in the Pyramid Registry

artículo científico publicado en 2018

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

artículo científico publicado en 2010

Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial.

artículo científico publicado en 2016

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

artículo científico publicado en 2015

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

artículo científico publicado en 2018

Molecular genetics in gastroenterology: from research success to clinical application?

artículo científico publicado en 2005

Molecular genetics of Crohn's disease

artículo científico publicado en 2004

More pediatric NOD2/CARD data

artículo científico publicado en 2004

Multidrug resistance (MDR1) gene in inflammatory bowel disease: a key player?

artículo científico publicado en 2005

Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers

scientific article published on 27 June 2018

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2

artículo científico publicado en 2012

Nationwide linkage analysis in Scotland-Has mortality following hospital admission for Crohn's disease changed in the early 21st century?

artículo científico publicado en 2014

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

artículo científico publicado en 2013

New genes in inflammatory bowel disease: lessons for complex diseases?

artículo científico publicado en 2006

Novel susceptibility genes in inflammatory bowel disease

artículo científico publicado en 2006

Paneth cell marker CD24 in NOD2 knockout organoids and in inflammatory bowel disease (IBD).

artículo científico publicado en 2013

Pathogenesis of Crohn's disease

artículo científico publicado en 2015

PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease

artículo científico publicado en 2009

Pharmacogenetics and inflammatory bowel disease: progress and prospects.

artículo científico publicado en 2004

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

artículo científico publicado en 2015

Potential role for the common cystic fibrosis ΔF508 mutation in Crohnʼs disease

artículo científico publicado en 2007

Precision medicine in inflammatory bowel disease: concept, progress and challenges

scientific article published on 28 January 2020

Predicting outcome in acute severe colitis - controversies in clinical practice in 2021

artículo científico publicado en 2021

Predicting outcomes in acute severe ulcerative colitis

artículo científico publicado en 2014

Predicting the need for colectomy in severe ulcerative colitis: a critical appraisal of clinical parameters and currently available biomarkers ⬇️

artículo científico publicado el 1 de enero de 2011

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

artículo científico publicado en 2007

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.

artículo científico publicado en 2018

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

artículo científico publicado en 2018

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

artículo científico publicado en 2011

Real-World Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: A Multi-Centre UK Experience

scientific article published on 13 April 2020

Reply to Daly and Rioux response

Resolution of non-small-cell lung cancer after withdrawal of anti-TNF therapy

scientific article published on 01 July 2008

Review article: impact of cigarette smoking on intestinal inflammation-direct and indirect mechanisms

scientific article published on 05 May 2020

Review article: withdrawal of 5-aminosalicylates in inflammatory bowel disease

scientific article published on 26 May 2020

Rising incidence of pediatric inflammatory bowel disease in Scotland.

artículo científico publicado en 2011

Role of infliximab in ulcerative colitis: further questions

artículo científico publicado en 2006

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

artículo científico publicado en 2007

Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype

artículo científico publicado en 2004

Serum C-reactive protein and CRP genotype in pediatric inflammatory bowel disease: influence on phenotype, natural history, and response to therapy

artículo científico publicado en 2015

Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases

artículo científico publicado en 2016

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

artículo científico publicado en 2018

Sight-threatening keratopathy complicating anti-TNF therapy in Crohn's disease: a case report

artículo científico publicado en 2014

Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis

artículo científico publicado en 2011

Smoking habit and load influence age at diagnosis and disease extent in ulcerative colitis

scientific article published on 01 March 2007

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

artículo científico publicado en 2020

Systematic Review of Effects of Withdrawal of Immunomodulators or Biologic Agents From Patients With Inflammatory Bowel Disease

artículo científico

Systematic meta-analyses and field synopsis of genetic and epigenetic studies in paediatric inflammatory bowel disease

artículo científico publicado en 2016

Systematic review: the role of breastfeeding in the development of pediatric inflammatory bowel disease

artículo científico publicado en 2009

TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's disease

artículo científico publicado en 2011

Technology insight: the application of proteomics in gastrointestinal disease

artículo científico publicado en 2007

The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis

artículo científico publicado en 2020

The Contribution of OCTN1/2 Variants Within the IBD5 Locus to Disease Susceptibility and Severity in Crohn’s Disease

artículo científico publicado en 2005

The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK

artículo científico publicado en 2019

The clinical course of ulcerative colitis after orthotopic liver transplantation for primary sclerosing cholangitis: further appraisal of immunosuppression post transplantation

artículo científico publicado en 2005

The genetics of Crohn's disease

artículo científico publicado en 2009

The genetics of inflammatory bowel disease

scientific article published on 25 September 2007

The hedgehog signalling pathway in the gastrointestinal tract: implications for development, homeostasis, and disease

artículo científico publicado en 2005

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing

artículo científico publicado en 2014

The intermediate filament protein, vimentin, is a regulator of NOD2 activity

artículo científico publicado en 2013

The role of genetics in Crohn's disease: how could it influence future therapies?

article

The role of glycosylation in IBD.

artículo científico publicado en 2014

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy

artículo científico publicado en 2019

Therapeutic decisions in inflammatory bowel disease in the SARS-Cov-2 pandemic

scientific article published on 15 June 2020

Therapeutic options in acute severe ulcerative colitis

artículo científico publicado en 2008

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

artículo científico publicado en 2005

Tuberous sclerosis‐2 (TSC2) regulates the stability of death‐associated protein kinase‐1 (DAPK) through a lysosome‐dependent degradation pathway ⬇️

artículo científico publicado el 6 de diciembre de 2010

Two-stage genome-wide methylation profiling in childhood-onset Crohn's Disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci.

artículo científico publicado en 2014

Use of methotrexate in refractory Crohn's disease: the Edinburgh experience

artículo científico publicado en 2008

Variation in ICOSLG influences Crohn's disease susceptibility

artículo científico publicado en 2011

What do the terms "genetic predisposition" and "genetic heterogeneity" mean in relation to inflammatory bowel disease?

artículo científico publicado en 2008

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