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Lista de obras de Markus Perola

A Functional variant of the iNOS gene flanking region is associated with LAD coronary artery disease: an autopsy study

article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A common variant near the KCNJ2 gene is associated with T-peak to T-end interval

artículo científico publicado en 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol

artículo científico publicado en 2012

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

artículo científico publicado en 2009

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A male-specific quantitative trait locus on 1p21 controlling human stature

artículo científico publicado en 2005

A metabolic view on menopause and ageing

artículo científico publicado en 2014

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

artículo científico publicado en 2010

A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction

scientific article published on March 2013

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

ACE gene and physical activity, blood pressure, and hypertension: a population study in Finland

artículo científico publicado en 2002

ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study

artículo científico publicado en 2009

AUTOGSCAN: Powerful Tools for Automated Genome-Wide Linkage and Linkage Disequilibrium Analysis

article

AUTOGSCAN: powerful tools for automated genome-wide linkage and linkage disequilibrium analysis

artículo científico publicado en 2005

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

artículo científico publicado en 2015

Affective responses to sweet products and sweet solution in British and Finnish adults

article

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

artículo científico publicado en 2015

Age-dependent association between hepatic lipase gene C-480T polymorphism and the risk of pre-hospital sudden cardiac death: the Helsinki Sudden Death Study

artículo científico publicado en 2006

Age-dependent interaction of apolipoprotein E gene with eastern birthplace in Finland affects severity of coronary atherosclerosis and risk of fatal myocardial infarction--Helsinki Sudden Death Study

artículo científico publicado en 2012

Ageing with elegans: a research proposal to map healthspan pathways

artículo científico publicado en 2016

Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

artículo científico publicado en 2014

An immune response network associated with blood lipid levels

artículo científico publicado en 2010

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

artículo científico publicado en 2017

Angiotensin-converting enzyme genotypes in the high- and low-risk area for coronary heart disease in Finland

artículo científico publicado en 1995

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

artículo científico publicado en 2000

Appetitive traits as behavioural pathways in genetic susceptibility to obesity: a population-based cross-sectional study

artículo científico publicado en 2015

Array-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population

artículo científico publicado en 1998

Association analysis of allelic variants of USF1 in coronary atherosclerosis

artículo científico publicado en 2008

Association of FXIII Val34Leu with decreased risk of myocardial infarction in Finnish males

artículo científico publicado en 1999

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

artículo científico publicado en 2018

Association of paraoxonase-1 M55L genotype and alcohol consumption with coronary atherosclerosis: the Helsinki Sudden Death Study

artículo científico publicado en 2004

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.

artículo científico publicado en 2009

Association of the endothelial nitric oxide synthase gene polymorphism with risk of coronary artery disease and myocardial infarction in middle-aged men.

artículo científico publicado en 2002

Association of variation in the interleukin-1 gene family with diabetes and glucose homeostasis

artículo científico publicado en 2009

Associations between interleukin-1 (IL-1) gene variations or IL-1 receptor antagonist levels and the development of type 2 diabetes

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Astringency Perception and Heritability Among Young Finnish Twins

BBMRI-ERIC as a resource for pharmaceutical and life science industries: the development of biobank-based Expert Centres

artículo científico publicado en 2015

Bayesian variable selection in searching for additive and dominant effects in genome-wide data

artículo científico publicado en 2012

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

artículo científico publicado en 2014

Birthplace in area with high coronary heart disease mortality predicts the severity of coronary atherosclerosis among middle-aged Finnish men who had migrated to capital area: The Helsinki Sudden Death Study

Birthplace predicts risk for prehospital sudden cardiac death in middle-aged men who migrated to metropolitan area: The Helsinki Sudden Death Study

artículo científico publicado en 2009

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

artículo científico publicado en 2017

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Cell specific eQTL analysis without sorting cells

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data

artículo científico publicado en 2016

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation

artículo científico publicado en 2014

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

artículo científico publicado en 2018

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

artículo científico publicado en 2014

Cohort Profile: The National FINRISK Study

artículo científico publicado en 2017

Cohort Profile: the Corogene study

artículo científico publicado en 2011

Combined Effects of Thrombosis Pathway Gene Variants Predict Cardiovascular Events

article

Combined effects of thrombosis pathway gene variants predict cardiovascular events

artículo científico publicado en 2007

Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci

artículo científico publicado en 2007

Combined genome scans for body stature in 6602 European twins: evidence for common Caucasian loci

Common genetic variants associated with sudden cardiac death: the FinSCDgen study

artículo científico publicado en 2012

Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study

artículo científico publicado en 2011

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals

artículo científico publicado en 2011

Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study

artículo científico publicado en 2009

Comprehensive catalog of European biobanks

artículo científico publicado en 2011

Correction to: Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Correction: Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

artículo científico publicado en 2019

Cortical ¹¹C-PIB uptake is associated with age, APOE genotype, and gender in "healthy aging".

artículo científico publicado en 2014

Data harmonization and federated analysis of population-based studies: the BioSHaRE project

artículo científico publicado en 2013

DataSHIELD: taking the analysis to the data, not the data to the analysis

artículo científico publicado en 2014

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

artículo científico publicado en 2011

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

artículo científico publicado en 2015

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Distribution and medical impact of loss-of-function variants in the Finnish founder population

artículo científico publicado en 2014

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence

artículo científico publicado en 2016

Environmental effects exceed genetic effects on perceived intensity and pleasantness of several odors: a three-population twin study

artículo científico publicado en 2008

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

European lactase persistence genotype shows evidence of association with increase in body mass index

artículo científico publicado en 2009

Evaluating whole genome amplification via multiply-primed rolling circle amplification for SNP genotyping of samples with low DNA yield

artículo científico publicado en 2005

Evaluation of HapMap data in six populations of European descent

artículo científico publicado en 2008

Evaluation of O2PLS in Omics data integration ⬇️

artículo científico publicado en 2016

Evidence of inbreeding depression on human height

artículo científico publicado en 2012

Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans

artículo científico publicado en 2007

Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder

artículo científico publicado en 2003

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

artículo científico publicado en 2017

Familial idiopathic normal pressure hydrocephalus

artículo científico publicado en 2016

Familial idiopathic normal pressure hydrocephalus.

artículo científico publicado en 2015

Family history and perceived risk of diabetes, cardiovascular disease, cancer, and depression

artículo científico publicado en 2016

Fine-Scale Genetic Structure in Finland

artículo científico publicado en 2017

Food Neophobia in Young Adults: Genetic Architecture and Relation to Personality, Pleasantness and Use Frequency of Foods, and Body Mass Index—A Twin Study

article by Antti J Knaapila et al published 16 October 2010 in Behavior Genetics

Food neophobia shows heritable variation in humans

artículo científico publicado en 2007

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

artículo científico publicado en 2013

Gender differences in genetic risk profiles for cardiovascular disease

artículo científico publicado en 2008

Genetic Risk Scores Predict Recurrence of Acute Coronary Syndrome

Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis

artículo científico publicado en 2017

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population

artículo científico publicado en 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and Environmental Contributions to Perceived Intensity and Pleasantness of Androstenone Odor: An International Twin Study

article by Antti J Knaapila et al published 3 January 2008 in Chemosensory perception

Genetic and environmental contributions to food use patterns of young adult twins

artículo científico publicado en 2007

Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis

artículo científico publicado en 2009

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic causal beliefs about morbidity: associations with health behaviors and health outcome beliefs about behavior changes between 1982-2002 in the Finnish population

artículo científico publicado en 2015

Genetic component of identification, intensity and pleasantness of odours: a Finnish family study

artículo científico publicado en 2007

Genetic contribution to sour taste preference

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits

artículo científico publicado en 2014

Genetic evidence of assortative mating in humans

article

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

artículo científico publicado en 2016

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetic variation of the interleukin-1 family and nongenetic factors determining the interleukin-1 receptor antagonist phenotypes

artículo científico publicado en 2010

Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis

artículo científico publicado en 2014

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genetics in an isolated population like Finland: a different basis for genomic medicine?

artículo científico publicado en 2017

Genetics of Human Stature: Lessons from Genome-Wide Association Studies ⬇️

artículo científico publicado el 7 de septiembre de 2011

Genetics of maximal walking speed and skeletal muscle characteristics in older women

artículo científico publicado en 2008

Genetics of platelet glycoprotein receptors: risk of thrombotic events and pharmacogenetic implications

artículo científico publicado en 2005

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families

artículo científico publicado en 2002

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population

artículo científico publicado en 2017

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

artículo científico publicado en 2016

Genome-Wide Meta-Analysis of Sciatica in Finnish Population

artículo científico publicado en 2016

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

artículo científico publicado en 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

artículo científico publicado en 2016

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association approaches for identifying loci for human height genes ⬇️

artículo científico publicado el 1 de febrero de 2011

Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts.

artículo científico publicado en 2017

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

artículo científico publicado en 2011

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

artículo científico publicado en 2012

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1

scientific journal article

Genome-wide association study of Hirschsprung disease detects a novel low-frequency variant at the RET locus

artículo científico publicado en 2018

Genome-wide association study of sleep duration in the Finnish population

artículo científico publicado en 2014

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

artículo científico publicado en 2013

Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects

scientific article published on 10 September 2008

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

artículo científico publicado en 2018

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Genome-wide search for QTLs for apolipoprotein A-I level in elderly Swedish DZ twins: evidence of female-specific locus on 15q11-13.

artículo científico publicado en 2008

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

artículo científico publicado en 2016

Genomic prediction of coronary heart disease

artículo científico publicado en 2016

Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis

artículo científico publicado en 2012

Geographical structure and differential natural selection among North European populations

scientific article published on 05 March 2009

Glycoprotein IIIa PlA1/A2 polymorphism and sudden cardiac death

scientific article published on 01 October 2000

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

artículo científico publicado en 2020

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

scholarly article by Alicia R Martin et al published 3 May 2018 in American Journal of Human Genetics

Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium

artículo científico publicado en 2016

Heritability and risk factors of uterine fibroids — The Finnish Twin Cohort Study

artículo científico publicado en 2000

Heritability of adult body height: a comparative study of twin cohorts in eight countries

artículo científico publicado en 2003

High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms

artículo científico publicado en 2014

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

artículo científico publicado en 2017

Identification of seven loci affecting mean telomere length and their association with disease

artículo científico publicado en 2013

Identifying flavor preference subgroups. Genetic basis and related eating behavior traits

artículo científico publicado en 2013

IgG Glycome in Colorectal Cancer

artículo científico publicado en 2016

Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels

artículo científico publicado en 2016

Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure

artículo científico publicado en 2012

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Lessons from studying monogenic disease for common disease

artículo científico publicado en 2006

Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia

artículo científico publicado en 2004

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

artículo científico publicado en 2017

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome

artículo científico publicado en 2017

Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability

artículo científico publicado en 2014

MORGAM (an international pooling of cardiovascular cohorts).

artículo científico publicado en 2004

Matrix metalloproteinase3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques

artículo científico publicado en 2004

Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity*

article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

artículo científico publicado en 2009

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging

artículo científico publicado en 2013

Metabolic profiling of alcohol consumption in 9778 young adults

artículo científico publicado en 2016

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence

artículo científico publicado en 2016

Metabolic signatures of birthweight in 18 288 adolescents and adults.

artículo científico publicado en 2016

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

artículo científico publicado en 2015

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

artículo científico publicado en 2016

Metabonomic, transcriptomic, and genomic variation of a population cohort

artículo científico publicado en 2010

Midlife alcohol consumption and later risk of cognitive impairment: a twin follow-up study

artículo científico publicado en 2010

Midlife cardiovascular risk factors and late cognitive impairment

scholarly article by Jyri J. Virta et al published 27 March 2013 in European Journal of Epidemiology

Midlife sleep characteristics associated with late life cognitive function

artículo científico publicado en 2013

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

artículo científico publicado en 2017

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

artículo científico publicado en 2018

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

artículo científico publicado en 2022

Myeloperoxidase gene variation as a determinant of atherosclerosis progression in the abdominal and thoracic aorta: an autopsy study.

artículo científico publicado en 2003

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome

artículo científico

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis

artículo científico publicado en 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism

artículo científico publicado en 2009

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Plasma N-glycans in colorectal cancer risk.

artículo científico publicado en 2018

Platelet collagen receptor GPIa (C807T/HPA-5) haplotype is not associated with an increased risk of fatal coronary events in middle-aged men

artículo científico publicado en 2002

Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men.

artículo científico publicado en 2004

Polymorphisms in the nephrin gene and diabetic nephropathy in type 1 diabetic patients

artículo científico publicado en 2003

Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population

artículo científico publicado en 2013

Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population

artículo científico publicado en 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies

artículo científico publicado en 2010

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

artículo científico publicado en 2020

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Risk alleles of USF1 gene predict cardiovascular disease of women in two prospective studies

artículo científico publicado en 2006

Same genetic components underlie different measures of sweet taste preference

artículo científico publicado en 2007

Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q.

artículo científico

Self-Ratings of Olfactory Function Reflect Odor Annoyance Rather than Olfactory Acuity

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

artículo científico publicado en 2010

Sex hormone-binding globulin associations with circulating lipids and metabolites and the risk for type 2 diabetes: observational and causal effect estimates

artículo científico publicado en 2015

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Shared genetic background for regulation of mood and sleep: association of GRIA3 with sleep duration in healthy Finnish women

artículo científico publicado en 2011

Smoking-dependent association between paraoxonase 1 M/L55 genotype and coronary atherosclerosis in males: an autopsy study

artículo científico publicado en 2003

Spline methods for the comparison of physical and genetic maps

artículo científico publicado en 2002

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

Testing genetic susceptibility loci for alcoholic heart muscle disease

artículo científico publicado en 2001

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

artículo científico publicado en 2015

The Effects of Intensive Weight Reduction on Body Composition and Serum Hormones in Female Fitness Competitors

artículo científico publicado en 2016

The GPIIIa (β3 integrin) PlA polymorphism in the early development of coronary atherosclerosis

article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Three-Factor Eating Questionnaire, body mass index, and responses to sweet and salty fatty foods: a twin study of genetic and environmental associations

artículo científico publicado en 2008

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

artículo científico publicado en 2013

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The impact of newly identified loci on coronary heart disease, stroke and total mortality in the MORGAM prospective cohorts

artículo científico publicado en 2009

The molecular genetic architecture of self-employment

artículo científico publicado en 2013

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

artículo científico publicado en 2014

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

artículo científico publicado en 2013

The transcriptional landscape of age in human peripheral blood

artículo científico publicado en 2015

The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

artículo científico publicado en 2011

Toward a roadmap in global biobanking for health

artículo científico publicado en 2012

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

artículo científico publicado en 2016

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Variation in the alpha2B-adrenoceptor gene as a risk factor for prehospital fatal myocardial infarction and sudden cardiac death

artículo científico publicado en 2003

Variation in the selenoprotein S gene locus is associated with coronary heart disease and ischemic stroke in two independent Finnish cohorts

article

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

artículo científico publicado en 2017

Within-family outliers: segregating alleles or environmental effects? A linkage analysis of height from 5815 sibling pairs

artículo científico publicado en 2008

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