Lista de obras - Stefan Steinbacher - Dominio Público Uruguay

(1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis ⬇️

artículo científico publicado el 10 de julio de 2012

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions ⬇️

artículo científico publicado el 24 de septiembre de 2010

Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii

artículo científico publicado en 2002

Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold

artículo científico publicado en 2003

Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate

artículo científico publicado en 2003

Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis

artículo científico publicado en 2003

Design of selective Cathepsin inhibitors

artículo científico publicado en 2009

Dipeptidyl nitrile inhibitors of Cathepsin L

artículo científico publicado en 2009

Discovery and Optimization of a Novel Series of Potent Mutant B-RafV600E Selective Kinase Inhibitors ⬇️

artículo científico publicado el 27 de febrero de 2013

Identification of azabenzimidazoles as potent JAK1 selective inhibitors

artículo científico publicado en 2016

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers ⬇️

artículo científico publicado el 6 de septiembre de 2011

Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors

artículo científico publicado en 2016

Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate

artículo científico publicado en 2004

Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans

artículo científico publicado en 2004

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments

artículo científico publicado en 2003

Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development

artículo científico publicado en 2003

Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

artículo científico publicado en 2002

Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate: implications for the catalytic mechanism

artículo científico publicado en 2003

Structure of the murine unglycosylated IgG1 Fc fragment

artículo científico publicado en 2009

The Crystal Structure of a Constitutively Active Mutant RON Kinase Suggests an Intramolecular Autophosphorylation Hypothesis ⬇️

artículo científico publicado el 21 de septiembre de 2010

The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase

artículo científico publicado en 2004

The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase

artículo científico publicado en 2002

Lista de obras de Stefan Steinbacher

(1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis ⬇️

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions ⬇️

Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii

Crystal structure of Schizosaccharomyces pombe riboflavin kinase reveals a novel ATP and riboflavin-binding fold

Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate

Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis

Design of selective Cathepsin inhibitors

Dipeptidyl nitrile inhibitors of Cathepsin L

Discovery and Optimization of a Novel Series of Potent Mutant B-RafV600E Selective Kinase Inhibitors ⬇️

Identification of azabenzimidazoles as potent JAK1 selective inhibitors

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers ⬇️

Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors

Metal sites in 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with the substrate ribulose 5-phosphate

Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments

Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development

Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

Structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase from Methanococcus jannaschii in complex with divalent metal ions and the substrate ribulose 5-phosphate: implications for the catalytic mechanism

Structure of the murine unglycosylated IgG1 Fc fragment

The Crystal Structure of a Constitutively Active Mutant RON Kinase Suggests an Intramolecular Autophosphorylation Hypothesis ⬇️

The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase

The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase