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Lista de obras de Karla Frydenvang

A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: synthesis, resolution, pharmacology, and crystal structure

artículo científico publicado en 2011

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

artículo científico publicado en 2007

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

artículo científico publicado en 2011

Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

artículo científico publicado en 2013

Kainate induces various domain closures in AMPA and kainate receptors

artículo científico publicado en 2012

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

artículo científico publicado en 2014

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

artículo científico publicado en 2008

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain

artículo científico publicado en 2014

Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

artículo científico publicado en 2012

Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization

artículo científico publicado en 2011

Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

artículo científico publicado en 2013

Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors

artículo científico publicado en 2016

Studies on an ( S )-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid (AMPA) Receptor Antagonist IKM-159: Asymmetric Synthesis, Neuroactivity, and Structural Characterization

artículo científico publicado en 2013

Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold

artículo científico publicado en 2013

Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

artículo científico publicado en 2012

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