Lista de obras - Michael Gajhede - Dominio Público Uruguay

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study

artículo científico publicado en 2005

A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase

artículo científico publicado en 1996

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

artículo científico publicado en 2007

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

artículo científico publicado en 2012

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

artículo científico publicado en 2007

A unique set of SH3-SH3 interactions controls IB1 homodimerization

artículo científico publicado en 2006

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity

artículo científico publicado en 2015

Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses

artículo científico publicado en 2004

Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family

artículo científico publicado en 2001

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

artículo científico publicado en 2000

Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase

artículo científico publicado en 2000

Band-structure methods for incommensurably modulated crystals: Application to the low-temperature phase of tetrathiafulvalene-tetracyanoquinodimethane (TTF-TCNQ)

artículo científico publicado en 1991

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

artículo científico publicado en 2011

Chaperone binding at the ribosomal exit tunnel

artículo científico publicado en 2003

Chemical and Thermal Unfolding of Calreticulin

artículo científico publicado en 2013

Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

artículo científico publicado en 2013

Conformational Stability of Calreticulin

article

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

artículo científico publicado en 2013

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

artículo científico publicado en 2012

Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network†

artículo científico publicado en 2005

Crystal structure of horseradish peroxidase C at 2.15 A resolution

artículo científico publicado en 1997

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

artículo científico publicado en 2004

Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping

artículo científico publicado en 2008

Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea

artículo científico publicado en 2004

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

artículo científico publicado en 2005

Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose

artículo científico publicado en 2001

Crystal structures of two peptide–HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

artículo científico publicado en 2006

Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab′ fragment

article

Crystallization and preliminary X-ray diffraction studies of a peroxidase from barley grain

scientific article published on 01 November 1992

Crystallization and preliminary X-ray diffraction studies on the Apo form of orotate phosphoribosyltransferase from Escherichia coli.

artículo científico publicado en 1994

Crystallization and preliminary X-ray investigation at 2.0 A resolution of Bet v 1, a birch pollen protein causing IgE-mediated allergy.

artículo científico publicado en 1996

Crystallization and preliminary X-ray studies of recombinant amylosucrase fromNeisseria polysaccharea

artículo científico publicado en 2000

Crystallization and preliminary X-ray studies of recombinant horseradish peroxidase

artículo científico publicado en 1995

Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein

artículo científico publicado en 2003

Crystallization of a stringent response factor from Aquifex aeolicus

artículo científico publicado en 2002

Cyclic lipoundecapeptide amphisin from Pseudomonas sp. strain DSS73.

artículo científico publicado en 2001

Cyclic lipoundecapeptide tensin fromPseudomonas fluorescensstrain 96.578

artículo científico publicado en 2000

Differential activity and structure of highly similar peroxidases. Spectroscopic, crystallographic, and enzymatic analyses of lignifying Arabidopsis thaliana peroxidase A2 and horseradish peroxidase A2

artículo científico publicado en 2001

Dimerization effect of sucrose octasulfate on rat FGF1

artículo científico publicado en 2008

Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2

artículo científico publicado en 2009

Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1

artículo científico publicado en 2000

Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis

artículo científico publicado en 2003

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

artículo científico publicado en 2015

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

article published in 2011

Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1.

artículo científico publicado en 2011

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

artículo científico publicado en 2005

Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.

artículo científico publicado en 2004

Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

artículo científico publicado en 2005

Expression, purification and characterization of the human MTA2-RBBP7 complex

artículo científico publicado en 2017

Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine

artículo científico publicado en 2009

High resolution crystal structures of the p120 RasGAP SH3 domain

artículo científico publicado en 2007

High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide

artículo científico publicado en 2005

Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state.

artículo científico publicado en 2017

Identification of catechols as histone-lysine demethylase inhibitors

artículo científico publicado en 2012

Increased amylosucrase activity and specificity, and identification of regions important for activity, specificity and stability through molecular evolution

artículo científico publicado en 2006

Inhibitors of histone demethylases

scientific article published on February 2011

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

artículo científico publicado en 2013

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

artículo científico publicado en 2012

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

artículo científico publicado en 2007

Kainate induces various domain closures in AMPA and kainate receptors

artículo científico publicado en 2012

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

artículo científico publicado en 2014

Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

artículo científico publicado en 2017

Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily

artículo científico publicado en 2001

Maltooligosaccharide disproportionation reaction: an intrinsic property of amylosucrase from Neisseria polysaccharea.

artículo científico publicado en 2002

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

artículo científico publicado en 2009

Molecular architecture of the Jumonji C family histone demethylase KDM5B

artículo científico publicado en 2019

Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple

artículo científico publicado en 2001

Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase.

artículo científico

Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors

artículo científico publicado en 2012

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

artículo científico publicado en 2008

Molecular modelling of human red blood cell pyruvate kinase: structural implications of a novel G1091 to a mutation causing severe nonspherocytic hemolytic anemia

artículo científico publicado en 1997

Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

artículo científico publicado en 2014

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain

artículo científico publicado en 2014

Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

artículo científico publicado en 2010

Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity

artículo científico publicado en 2002

Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

artículo científico publicado en 2010

Pancreatic spasmolytic polypeptide: Crystallization, circular dichroism analysis, and preliminary X-ray diffraction studies

scholarly article by Michael Gajhede published in August 1992

Pancreatic spasmolytic polypeptide: first three-dimensional structure of a member of the mammalian trefoil family of peptides

artículo científico publicado en 1993

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

artículo científico publicado en 2007

Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes

artículo científico publicado en 2018

Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

artículo científico publicado en 2012

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

artículo científico publicado en 2015

Plant peroxidases: substrate complexes with mechanistic implications

artículo científico publicado en 2001

Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Chinnock

scientific article published in 2021

Role of CD3 gamma in T cell receptor assembly.

artículo científico publicado en 1996

Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR.

artículo científico publicado en 2017

Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

artículo científico publicado en 2008

Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity

artículo científico publicado en 2017

Structural Studies of Nicotinic Acetylcholine Receptors: Using Acetylcholine-Binding Protein as a Structural Surrogate.

artículo científico publicado en 2015

Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain

artículo científico publicado en 2013

Structural analysis of the two horseradish peroxidase catalytic residue variants H42E and R38S/H42E: implications for the catalytic cycle

artículo científico publicado en 2002

Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors

artículo científico publicado en 2014

Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family

artículo científico publicado en 2004

Structural interactions between horseradish peroxidase C and the substrate benzhydroxamic acid determined by X-ray crystallography

artículo científico publicado en 1998

Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule

artículo científico publicado en 2011

Structural mutations of C-domains in members of the Ig superfamily. Consequences for the interactions between the T cell antigen receptor and the zeta 2 homodimer

artículo científico publicado en 1992

Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites

artículo científico publicado en 2007

Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion.

artículo científico

Structure analysis of modulated molecular crystals: The modulated phase of thiourea as described by a molecular displacement model

article

Structure and binding properties of a cameloid nanobody raised against KDM5B.

artículo científico publicado en 2015

Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.

artículo científico publicado en 2006

Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501

artículo científico publicado en 2008

Structure of barley grain peroxidase refined at 1.9-A resolution. A plant peroxidase reversibly inactivated at neutral pH

artículo científico publicado en 1998

Structure of porcine pancreatic spasmolytic polypeptide at 1.95 A resolution.

artículo científico publicado en 1996

Structure of rat acidic fibroblast growth factor at 1.4 Å resolution

artículo científico publicado en 2007

Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom.

artículo científico publicado en 2006

Structure of soybean seed coat peroxidase: A plant peroxidase with unusual stability and haem-apoprotein interactions

artículo científico publicado en 2001

Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

artículo científico publicado en 2008

Structure of the first PDZ domain of human PSD-93

artículo científico publicado en 2009

Structure of the house dust mite allergen Der f 2: implications for function and molecular basis of IgE cross-reactivity

artículo científico publicado en 2005

Structure-Based Design of a New Scaffold for Cell-Penetrating Peptidic Inhibitors of the Histone Demethylase PHF8.

artículo científico publicado en 2017

Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

artículo científico publicado en 2008

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

artículo científico publicado en 2012

Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists

artículo científico publicado en 2013

Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

artículo científico publicado en 2011

The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

scientific article published on 04 March 2020

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure

artículo científico publicado en 2005

The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove

artículo científico publicado en 2009

The crystal structure of recombinant proDer p 1, a major house dust mite proteolytic allergen

artículo científico publicado en 2005

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

artículo científico publicado en 2009

The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region.

artículo científico publicado en 2017

The metal binding site of the major house dust mite allergen Der p 1

artículo científico publicado en 2006

The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

artículo científico publicado en 2017

The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.

artículo científico publicado en 2006

The structure of amylosucrase fromDeinococcus radioduranshas an unusual open active-site topology

artículo científico publicado en 2013

The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit

artículo científico publicado en 2008

The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1.

artículo científico publicado en 2016

The structures of the horseradish peroxidase C-ferulic acid complex and the ternary complex with cyanide suggest how peroxidases oxidize small phenolic substrates

artículo científico publicado en 1999

Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

artículo científico publicado en 2012

Three-dimensional structure and epitopes of Bet v 1

article

Towards the molecular understanding of glycogen elongation by amylosucrase

artículo científico publicado en 2007

Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.

artículo científico publicado en 2013

Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.

artículo científico publicado en 2004

X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy

artículo científico publicado en 1996

Lista de obras de Michael Gajhede

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study

A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

A tetrazolyl-substituted subtype-selective AMPA receptor agonist

A unique set of SH3-SH3 interactions controls IB1 homodimerization

Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity

Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE binding but retains protein folding pattern for induction of protective blocking-antibody responses

Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase

Band-structure methods for incommensurably modulated crystals: Application to the low-temperature phase of tetrathiafulvalene-tetracyanoquinodimethane (TTF-TCNQ)

Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate

Chaperone binding at the ribosomal exit tunnel

Chemical and Thermal Unfolding of Calreticulin

Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

Conformational Stability of Calreticulin

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-D-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network†

Crystal structure of horseradish peroxidase C at 2.15 A resolution

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping

Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose

Crystal structures of two peptide–HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype

Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab′ fragment

Crystallization and preliminary X-ray diffraction studies of a peroxidase from barley grain

Crystallization and preliminary X-ray diffraction studies on the Apo form of orotate phosphoribosyltransferase from Escherichia coli.

Crystallization and preliminary X-ray investigation at 2.0 A resolution of Bet v 1, a birch pollen protein causing IgE-mediated allergy.

Crystallization and preliminary X-ray studies of recombinant amylosucrase fromNeisseria polysaccharea

Crystallization and preliminary X-ray studies of recombinant horseradish peroxidase

Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein

Crystallization of a stringent response factor from Aquifex aeolicus

Cyclic lipoundecapeptide amphisin from Pseudomonas sp. strain DSS73.

Cyclic lipoundecapeptide tensin fromPseudomonas fluorescensstrain 96.578

Differential activity and structure of highly similar peroxidases. Spectroscopic, crystallographic, and enzymatic analyses of lignifying Arabidopsis thaliana peroxidase A2 and horseradish peroxidase A2

Dimerization effect of sucrose octasulfate on rat FGF1

Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2

Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1

Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1.

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1.

Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1

Expression, purification and characterization of the human MTA2-RBBP7 complex

Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine

High resolution crystal structures of the p120 RasGAP SH3 domain

High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide

Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state.

Identification of catechols as histone-lysine demethylase inhibitors

Increased amylosucrase activity and specificity, and identification of regions important for activity, specificity and stability through molecular evolution

Inhibitors of histone demethylases

Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

Kainate induces various domain closures in AMPA and kainate receptors

L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain

Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily

Maltooligosaccharide disproportionation reaction: an intrinsic property of amylosucrase from Neisseria polysaccharea.

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

Molecular architecture of the Jumonji C family histone demethylase KDM5B

Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple

Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase.

Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors

Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

Molecular modelling of human red blood cell pyruvate kinase: structural implications of a novel G1091 to a mutation causing severe nonspherocytic hemolytic anemia

Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors

Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand binding domain

Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity

Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

Pancreatic spasmolytic polypeptide: Crystallization, circular dichroism analysis, and preliminary X-ray diffraction studies

Pancreatic spasmolytic polypeptide: first three-dimensional structure of a member of the mammalian trefoil family of peptides

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid