Lista de obras - Ronen Marmorstein - Dominio Público Uruguay

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions ⬇️

artículo científico publicado el 12 de abril de 2011

Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation

artículo científico publicado en 2016

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

artículo científico publicado en 2010

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

artículo científico publicado en 2003

Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

artículo científico publicado en 2014

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

artículo científico publicado en 2013

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

artículo científico publicado en 2008

Identification of a Novel Family of BRAF V600E Inhibitors

artículo científico publicado en 2012

Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog

artículo científico publicado en 2013

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1

artículo científico publicado en 2005

Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme

artículo científico publicado en 2007

Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA

artículo científico publicado en 2013

Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates

artículo científico publicado en 2003

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

artículo científico publicado en 2013

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

artículo científico publicado en 2008

Structural Basis for Dimerization in DNA Recognition by Gal4

artículo científico publicado en 2008

Structural Basis for Histone and Phosphohistone Binding by the GCN5 Histone Acetyltransferase ⬇️

artículo científico publicado el 1 de agosto de 2003

Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes

artículo científico publicado en 2007

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

artículo científico publicado en 2008

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

artículo científico publicado en 2004

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

artículo científico publicado en 2011

Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus

artículo científico publicado en 2009

Structure and autoregulation of the yeast Hst2 homolog of Sir2 ⬇️

artículo científico publicado el 21 de septiembre de 2003

Structure and mechanism of non‐histone protein acetyltransferase enzymes ⬇️

artículo científico publicado el 28 de junio de 2013

Structure of Vps75 and implications for histone chaperone function

artículo científico publicado en 2008

Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA binding

artículo científico publicado en 2003

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

artículo científico publicado en 2011

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

artículo científico publicado en 2006

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

artículo científico publicado en 2002

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation ⬇️

artículo científico publicado el 20 de enero de 2011

Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide ⬇️

artículo científico publicado el 1 de noviembre de 2003

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

artículo científico publicado en 2006

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

artículo científico publicado en 2014

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

artículo científico publicado en 2007

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

artículo científico publicado en 2008

Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity

artículo científico publicado en 2002

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

artículo científico publicado en 2008

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

artículo científico publicado en 2012

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

artículo científico publicado en 2009

The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate

artículo científico publicado en 2002

The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting

artículo científico publicado en 2007

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

artículo científico publicado en 2008

The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain

artículo científico publicado en 2007

Lista de obras de Ronen Marmorstein

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin's Regulation of Mitogenic Signaling and Tumor Suppressive Functions ⬇️

Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAFV600E Conformation

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrate

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

Identification of a Novel Family of BRAF V600E Inhibitors

Implications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal ortholog

Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1

Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme

Molecular Basis for Oligomeric-DNA Binding and Episome Maintenance by KSHV LANA

Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates

Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

Structural Basis for Dimerization in DNA Recognition by Gal4

Structural Basis for Histone and Phosphohistone Binding by the GCN5 Histone Acetyltransferase ⬇️

Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes

Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus

Structure and autoregulation of the yeast Hst2 homolog of Sir2 ⬇️

Structure and mechanism of non‐histone protein acetyltransferase enzymes ⬇️

Structure of Vps75 and implications for histone chaperone function

Structure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA binding

Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation

Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly

Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation ⬇️

Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide ⬇️

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

Structure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and Selectivity

Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity

Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes

The Art of Filling Protein Pockets Efficiently with Octahedral Metal Complexes

The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase

The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate

The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting

The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain