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Lista de obras de Jamie Rossjohn

221 Structure-function characterization of type I interferon receptor signaling regulation

A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses

artículo científico publicado en 2006

A Green Fluorescent Protein Containing a QFG Tri-Peptide Chromophore: Optical Properties and X-Ray Crystal Structure

artículo científico publicado en 2012

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

artículo científico publicado en 2011

A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells

artículo científico publicado en 2011

A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism

artículo científico publicado en 2014

A Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell Recognition

artículo científico publicado en 2003

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals

artículo científico publicado en 2020

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene

artículo científico publicado en 2017

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

artículo científico publicado en 2007

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

artículo científico publicado en 2019

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

artículo científico publicado en 2019

A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family

artículo científico publicado en 2017

A biased view toward celiac disease

artículo científico publicado en 2016

A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway

artículo científico publicado en 2004

A bird's eye view of NK cell receptor interactions with their MHC class I ligands

artículo científico

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

scientific article published on 01 December 2019

A common fold mediates vertebrate defense and bacterial attack

artículo científico publicado en 2007

A conserved energetic footprint underpins recognition of Human Leukocyte Antigen-E by two distinct αβ T cell receptors

artículo científico publicado en 2017

A conserved human T cell population targets mycobacterial antigens presented by CD1b

artículo científico publicado en 2013

A homology model for the human theta-class glutathione transferase T1-1.

artículo científico publicado en 1998

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

artículo científico publicado en 2017

A long, naturally presented immunodominant epitope from NY-ESO-1 tumor antigen: implications for cancer vaccine design

artículo científico publicado en 2009

A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells

A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

artículo científico publicado en 2008

A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications

artículo científico publicado en 1998

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

artículo científico publicado en 2013

A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells

artículo científico publicado en 2013

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

artículo científico publicado en 2017

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

artículo científico publicado en 2014

A mortise-tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

artículo científico publicado en 2014

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

artículo científico publicado en 2019

A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability

artículo científico publicado en 2014

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

artículo científico publicado en 2007

A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b

artículo científico publicado en 2012

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition.

artículo científico publicado en 2006

A structural basis for selection of the mucosal associated invariant T cell receptor in MR1-restricted antigen recognition

A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins

artículo científico publicado en 2007

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

artículo científico publicado en 2003

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule

artículo científico publicado en 2012

A structural characterization of the isoniazidMycobacterium tuberculosisdrug target, Rv2971, in its unliganded form

artículo científico publicado en 2014

A structural perspective on MHC class Ib molecules in adaptive immunity

artículo científico publicado en 2006

A structural voyage toward an understanding of the MHC‐I‐restricted immune response: lessons learned and much to be learned

artículo científico publicado el 1 de noviembre de 2012

A structurally derived consensus pattern for theta class glutathione transferases

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

scientific article published on 29 July 2019

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

artículo científico publicado en 2016

AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.

artículo científico publicado en 2006

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

artículo científico publicado en 2020

Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides

artículo científico publicado en 2013

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

artículo científico publicado en 2009

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

artículo científico publicado en 2009

Aerolysin and pertussis toxin share a common receptor-binding domain

artículo científico publicado en 1997

Aerolysin--a paradigm for membrane insertion of beta-sheet protein toxins?

artículo científico publicado en 1998

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses

artículo científico publicado en 2011

Allelic polymorphism in the T cell receptor and its impact on immune responses

artículo científico publicado en 2010

Alloreactivity

artículo científico publicado en 2013

Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry

artículo científico publicado en 2006

Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.

artículo científico publicado en 2010

Amino acid substitutions around the chromophore of the chromoprotein Rtms5 influence polypeptide cleavage

artículo científico publicado en 2005

An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant

artículo científico publicado en 2014

An overview on the identification of MAIT cell antigens.

artículo científico publicado en 2018

Antagonism of antiviral and allogeneic activity of a human public CTL clonotype by a single altered peptide ligand: implications for allograft rejection

artículo científico publicado en 2005

Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.

artículo científico publicado en 2015

Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor

artículo científico publicado en 2009

Antigen recognition by CD1d-restricted NKT T cell receptors.

artículo científico publicado en 2009

Antigen-driven patterns of TCR bias are shared across diverse outcomes of human hepatitis C virus infection

artículo científico publicado en 2010

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

artículo científico publicado en 2013

Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

artículo científico publicado en 2000

Atypical TRAV1-2- T cell receptor recognition of the antigen-presenting molecule MR1

artículo científico publicado en 2020

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

artículo científico publicado en 2016

Author Correction: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

artículo científico publicado en 2020

Beta-testing NKT cell self-reactivity

artículo científico publicado en 2011

Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease

artículo científico publicado en 2012

Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with alphavbeta3 negatively modulates IGF-I-mediated migration and tumor growth.

artículo científico publicado en 2004

Broad CD8 T cell cross-recognition of distinct influenza A strains in humans

artículo científico publicado en 2018

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

artículo científico publicado en 2013

CD1a on Langerhans cells controls inflammatory skin disease.

artículo científico publicado en 2016

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

artículo científico publicado en 2013

CD1d antigen presentation: treats for NKT cells

CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells

artículo científico publicado en 2013

CD1d-lipid antigen recognition by the γδ TCR

artículo científico publicado en 2013

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

artículo científico publicado en 2007

CD4 + T cell–mediated HLA class II cross-restriction in HIV controllers

article

CD8<sup>+</sup> T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

artículo científico publicado en 2021

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

artículo científico publicado en 2008

CTL recognition of a bulged viral peptide involves biased TCR selection

artículo científico publicado en 2005

Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph

artículo científico publicado en 2019

Circulating gluten-specific FOXP3+CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease.

artículo científico publicado en 2017

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries)

artículo científico publicado en 2015

Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages

artículo científico publicado en 2013

Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin

artículo científico publicado en 2013

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens

artículo científico

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy

artículo científico publicado en 2008

Comprehensive, quantitative mapping of T cell epitopes in gluten in celiac disease.

artículo científico publicado en 2010

Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

artículo científico publicado en 2010

Correction: Article on Vaccination Reveals a Long Dominant CTL Epitope

Corrigendum: The burgeoning family of unconventional T cells

scholarly article published in Nature Immunology

Corrigendum: The burgeoning family of unconventional T cells.

artículo científico publicado en 2016

Cross-reactive CD8 + T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

artículo científico publicado en 2010

Crystal structure and comparative functional analyses of a Mycobacterium aldo-keto reductase

artículo científico publicado en 2010

Crystal structure of HLA-G: a nonclassical MHC class I molecule expressed at the fetal-maternal interface

artículo científico publicado en 2005

Crystal structure of LipL32, the most abundant surface protein of pathogenic Leptospira spp

artículo científico publicado en 2009

Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases

artículo científico publicado en 2010

Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species

artículo científico publicado en 2008

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.

artículo científico publicado en 2016

Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein

artículo científico publicado en 1999

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

artículo científico publicado en 2004

Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state

artículo científico publicado en 2009

Crystallization and preliminary X-ray analysis of a bacterial glutathione transferase

artículo científico publicado en 1996

Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin

artículo científico publicado en 1996

Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase

artículo científico publicado en 1997

Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo.

scientific article published on 02 October 2013

Cytomegalovirus replication is associated with enrichment of distinct γδ T cell subsets following lung transplantation: A novel therapeutic approach?

scientific article published on 26 August 2020

Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes

artículo científico publicado en 2017

DEC-205 is a cell surface receptor for CpG oligonucleotides

artículo científico publicado en 2012

Degenerate recognition of MHC class I molecules with Bw4 and Bw6 motifs by a killer cell Ig-like receptor 3DL expressed by macaque NK cells.

artículo científico publicado en 2012

Determinants of gliadin-specific T cell selection in celiac disease

artículo científico publicado en 2015

Determination of chromophore charge states in the low pH color transition of the fluorescent protein Rtms5H146S via time-dependent DFT

Dichloromethane mediated in vivo selection and functional characterization of rat glutathione S-transferase theta 1-1 variants

scientific journal article

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

artículo científico publicado en 2009

Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function

artículo científico publicado en 2018

Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes

article by Shiva Dahal-Koirala et al published 18 January 2019 in Journal of Biological Chemistry

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

artículo científico publicado en 2006

Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit

artículo científico publicado en 2016

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains

artículo científico publicado en 2009

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

scientific article published on 20 November 2019

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.

artículo científico publicado en 2018

Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution

artículo científico publicado en 2016

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition

artículo científico publicado en 2016

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells

artículo científico publicado en 2017

Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex

artículo científico

Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.

artículo científico publicado en 2017

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity

artículo científico publicado en 2018

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

artículo científico publicado en 2018

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit

artículo científico publicado en 2013

Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity

artículo científico publicado en 2013

Effects of a local auxiliary protein on the two-dimensional affinity of a TCR-peptide MHC interaction

artículo científico publicado en 2020

Endogenous antigen presentation impacts on T-box transcription factor expression and functional maturation of CD8+ T cells

artículo científico publicado en 2012

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

scientific article published on 21 September 2020

Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences

artículo científico publicado en 2003

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence

artículo científico publicado en 2008

Epitope-specific TCR  repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides

artículo científico publicado en 2008

Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

artículo científico publicado en 2015

Erratum: Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells

scholarly article by Daniel M Andrews et al published April 2013 in Nature Immunology

Escape from highly effective public CD8+ T-cell clonotypes by HIV

artículo científico publicado en 2011

Evaluation of the role of two conserved active-site residues in beta class glutathione S-transferases

artículo científico publicado en 2000

Expression, purification, crystallization and preliminary X-ray analysis of eCGP123, an extremely stable monomeric green fluorescent protein with reversible photoswitching properties.

artículo científico publicado en 2011

Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

artículo científico publicado en 2008

Expression, purification, crystallization and preliminary X-ray diffraction analysis of an essential lipoprotein implicated in cell-wall biosynthesis in Mycobacteria

artículo científico publicado en 2005

Fighting infection with your MAITs

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

artículo científico publicado en 2018

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

artículo científico publicado en 2021

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.

artículo científico publicado en 2015

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue

artículo científico publicado en 2004

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

artículo científico publicado en 2016

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

artículo científico publicado en 2007

Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1

scientific article published on 20 January 2020

Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response

artículo científico publicado en 2017

Germline-encoded recognition of diverse glycolipids by natural killer T cells

article

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

artículo científico publicado en 2016

HLA peptide length preferences control CD8+ T cell responses

artículo científico publicado en 2013

HLA variation and disease

artículo científico publicado en 2018

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells

artículo científico publicado en 2020

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

artículo científico publicado en 2018

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

artículo científico publicado en 2014

Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability

artículo científico publicado en 2010

Have we cut ourselves too short in mapping CTL epitopes?

artículo científico publicado en 2005

High resolution structures of highly bulged viral epitopes bound to major histocompatibility complex class I. Implications for T-cell receptor engagement and T-cell immunodominance

artículo científico publicado en 2005

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

artículo científico publicado en 2013

Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis

artículo científico publicado en 2006

Host immunomodulatory lipids created by symbionts from dietary amino acids

artículo científico publicado en 2021

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

artículo científico publicado en 2016

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

artículo científico publicado en 2016

How a Home-Grown T Cell Receptor Interacts with a Foreign Landscape

How opposites attract

artículo científico publicado el 7 de diciembre de 2010

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

scientific article published on 18 February 2019

Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

scientific article published on 27 January 2020

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products

artículo científico publicado en 2020

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens

artículo científico publicado en 2016

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

artículo científico publicado en 2012

Human autoreactive T cells recognize CD1b and phospholipids

artículo científico publicado en 2015

Human glutathione transferase P1-1 and nitric oxide carriers; a new role for an old enzyme

artículo científico publicado en 2001

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

artículo científico publicado en 2008

Human leukocyte antigen-associated drug hypersensitivity

artículo científico publicado el 8 de noviembre de 2012

Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation

artículo científico publicado en 2016

Human skin is colonized by T cells that recognize CD1a independently of lipid

artículo científico publicado en 2021

Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site

artículo científico publicado en 1998

Human γδ T cells recognize CD1b by two distinct mechanisms

scientific article published on 31 August 2020

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

artículo científico publicado en 2019

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

artículo científico publicado en 2015

Identification of Native and Post-Translationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

artículo científico publicado en 2018

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

artículo científico publicado en 1998

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.

artículo científico publicado en 2015

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex

artículo científico publicado en 2002

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

artículo científico publicado en 2015

Identification of self-antigen-specific T cells reflecting loss of tolerance in autoimmune disease underpins preventative immunotherapeutic strategies in rheumatoid arthritis

artículo científico publicado en 2014

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens

artículo científico publicado en 2004

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

artículo científico publicado en 2012

Immune self-reactivity triggered by drug-modified human leukocyte antigen-peptide presentation

Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection

artículo científico publicado en 2008

Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses

artículo científico publicado en 2018

Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin

artículo científico publicado en 2008

Insight into the basis of autonomous immunoreceptor activation

artículo científico publicado en 2011

Interferon-ε protects the female reproductive tract from viral and bacterial infection

scientific journal article

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

artículo científico publicado en 2016

Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.

artículo científico publicado en 2018

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

artículo científico publicado en 2011

Lack of heterologous cross-reactivity towards HLA-A*02:01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures

artículo científico publicado en 2016

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

artículo científico publicado en 2005

Lipid and small-molecule display by CD1 and MR1.

artículo científico

Lipids hide or step aside for CD1-autoreactive T cell receptors.

artículo científico publicado en 2018

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

artículo científico publicado en 2012

MAIT cells and MR1-antigen recognition

artículo científico publicado en 2017

MAIT cells are depleted early but retain functional cytokine expression in HIV infection

artículo científico publicado en 2014

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immun

artículo científico publicado en 2017

MAIT cells protect against pulmonary Legionella longbeachae infection

artículo científico publicado en 2018

MAITs, MR1 and vitamin B metabolites

artículo científico

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

artículo científico publicado en 2017

MR1 presentation of vitamin B-based metabolite ligands.

artículo científico publicado en 2015

MR1 presents microbial vitamin B metabolites to MAIT cells

artículo científico publicado en 2012

Managing and mining protein crystallization data.

artículo científico publicado en 2006

Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire

article

Molecular Imprint of Exposure to Naturally Occurring Genetic Variants of Human Cytomegalovirus on the T cell Repertoire

artículo científico publicado en 2014

Molecular architecture of the αβ T cell receptor-CD3 complex

artículo científico publicado en 2014

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.

artículo científico publicado en 2017

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

artículo científico publicado en 2016

Molecular basis of glutathione synthetase deficiency and a rare gene permutation event

artículo científico publicado en 1999

More than one reason to rethink the use of peptides in vaccine design

artículo científico publicado en 2007

Movement of a Loop in Domain 3 of Aerolysin Is Required for Channel Formation†

artículo científico publicado en 1998

Mucosa-Associated Invariant T Cells Are Systemically Depleted in Simian Immunodeficiency Virus-Infected Rhesus Macaques

artículo científico publicado en 2016

Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate

artículo científico publicado en 2021

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection

artículo científico publicado en 2018

Mucosal-Associated Invariant T cell receptor recognition of small molecules presented by MR1.

artículo científico publicado en 2018

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

artículo científico publicado en 2015

Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity

scientific article published on 24 July 2020

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.

artículo científico publicado en 2016

Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme

artículo científico publicado en 1997

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

artículo científico publicado en 2014

NKT TCR Recognition of CD1d- -C-Galactosylceramide

artículo científico publicado en 2011

NKT cells: the smoking gun in fungal-induced asthma?

artículo científico publicado en 2013

Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion

artículo científico publicado en 2004

Natural Killer T cell obsession with self-antigens

artículo científico publicado en 2013

Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

artículo científico publicado en 2009

Naturally processed non-canonical HLA-A*02:01 presented peptides

artículo científico publicado en 2014

New ways to turn on NKT cells

artículo científico publicado en 2011

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility

artículo científico publicado en 2021

O009 Fine structural and functional characterization of a unique IFNβ–Ifnar1 signaling axis

Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection

scientific article published on 31 August 2020

Peptide length determines the outcome of TCR/peptide-MHCI engagement

artículo científico publicado en 2013

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

artículo científico publicado en 2018

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.

artículo científico publicado en 2015

Phospholipid signaling in innate immune cells

artículo científico publicado en 2018

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

artículo científico publicado en 2009

Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

artículo científico publicado en 2013

Post-translationally modified T cell epitopes: immune recognition and immunotherapy

artículo científico publicado en 2009

Predisposed αβ T cell antigen receptor recognition of MHC and MHC-I like molecules?

artículo científico

Preemptive priming readily overcomes structure-based mechanisms of virus escape

artículo científico publicado en 2013

Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities

artículo científico publicado en 2014

Preliminary X-ray crystallographic studies of a newly defined human theta-class glutathione transferase.

artículo científico publicado en 1998

Prevention of Cytotoxic T Cell Escape Using a Heteroclitic Subdominant Viral T Cell Determinant

artículo científico publicado en 2008

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

artículo científico publicado en 2010

Public T cell receptors confer high-avidity CD4 responses to HIV controllers

artículo científico publicado en 2016

Purification and biological characterization of soluble, recombinant mouse IFNβ expressed in insect cells

artículo científico publicado en 2013

Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity

artículo científico publicado en 2011

Recent advances in all-protein chromophore technology

artículo científico publicado en 2006

Recipient mucosal-associated invariant T cells control GVHD within the colon.

artículo científico publicado en 2018

Recognition of CD1d-restricted antigens by natural killer T cells

artículo científico publicado en 2012

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

artículo científico publicado en 2012

Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

artículo científico publicado en 2015

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

artículo científico publicado en 2018

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs.

artículo científico publicado en 2013

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).

artículo científico publicado en 2017

Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.

artículo científico publicado en 2016

Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.

artículo científico publicado en 2012

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

artículo científico publicado en 2013

Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions

artículo científico publicado en 2016

Repeated infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire

artículo científico publicado en 2021

Reply to Roudier et al.: HLA-DRB1 polymorphism, anti-citrullinated protein antibodies, and rheumatoid arthritis.

artículo científico publicado en 2018

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response

artículo científico publicado en 2016

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

artículo científico publicado en 2015

Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae

article

Shedding light on MHC class I antigen loading: a UV-labile peptide ligand approach

Shifting Substrate Specificity of Human Glutathione Transferase (from Class Pi to Class Alpha) by a Single Point Mutation

artículo científico publicado en 1998

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

artículo científico publicado en 2018

Site-directed mutagenesis of theProteus mirabilisglutathione transferase B1-1 G-site

scientific article published on 01 February 1998

Specificity on a knife-edge: the alphabeta T cell receptor

artículo científico publicado en 2006

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.

artículo científico publicado en 2017

Structural Basis of Subtilase Cytotoxin SubAB Assembly

artículo científico publicado en 2013

Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes

artículo científico publicado en 2014

Structural and Sequence Comparisons of Quinone Oxidoreductase, ζ-Crystallin, and Glucose and Alcohol Dehydrogenases

article

Structural and biochemical characterization of the oxidoreductase NmDsbA3 from Neisseria meningitidis

artículo científico publicado en 2008

Structural and biological basis of CTL escape in coronavirus-infected mice

artículo científico publicado en 2008

Structural and regulatory diversity shape HLA-C protein expression levels

artículo científico publicado en 2017

Structural basis for a major histocompatibility complex class Ib-restricted T cell response

scientific journal article

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses

artículo científico publicado en 2011

Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes

artículo científico publicado en 2012

Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

scientific journal article

Structural determinants of T-cell receptor bias in immunity

artículo científico publicado en 2006

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface

artículo científico

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

artículo científico publicado en 2012

Structural insight into natural killer T cell receptor recognition of CD1d

artículo científico publicado en 2007

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C

artículo científico publicado en 2021

Structural studies on HLA-G: implications for ligand and receptor binding

artículo científico publicado en 2006

Structural studies on the alphabeta T-cell receptor

artículo científico publicado en 2005

Structure and function of the oxidoreductase DsbA1 from Neisseria meningitidis

artículo científico publicado en 2009

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

artículo científico publicado en 1997

Structure of the Chicken CD3  /  Heterodimer and Its Assembly with the   T Cell Receptor

artículo científico publicado en 2014

Structure, biological functions and applications of the AB5 toxins

artículo científico publicado en 2010

Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins

artículo científico publicado en 2017

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins

artículo científico publicado en 2007

Structures of thermolabile mutants of human glutathione transferase P1-1

artículo científico publicado en 2000

Studies on the structure and mechanism of a bacterial protein toxin by analytical ultracentrifugation and small-angle neutron scattering

artículo científico publicado en 1999

Suboptimal SARS-CoV-2-specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

artículo científico publicado en 2020

Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors

artículo científico publicado en 2008

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells

artículo científico publicado en 2015

T cell allorecognition and MHC restriction--A case of Jekyll and Hyde?

artículo científico publicado en 2007

T cell allorecognition via molecular mimicry

artículo científico publicado en 2009

T cell antigen receptor recognition of antigen-presenting molecules

artículo científico

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

artículo científico publicado en 2018

T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo

artículo científico publicado en 2005

T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire

artículo científico publicado en 2009

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

artículo científico publicado en 2019

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

artículo científico publicado en 2016

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

artículo científico publicado en 2005

T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8

artículo científico publicado en 2021

T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex

artículo científico publicado en 2015

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

artículo científico publicado en 2014

T-cell allorecognition: a case of mistaken identity or déjà vu?

artículo científico publicado en 2008

T-cell receptor bias and immunity

scientific article published on 18 January 2008

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease

artículo científico publicado en 2014

T-cells behaving badly: structural insights into alloreactivity and autoimmunity

artículo científico publicado en 2008

TAP genes and immunity

artículo científico publicado en 2004

TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope

artículo científico publicado en 2006

TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire

artículo científico publicado en 2014

Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies.

artículo científico publicado en 2016

Targeting of a natural killer cell receptor family by a viral immunoevasin

artículo científico publicado en 2013

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.

artículo científico publicado en 2015

Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability

scientific journal article

Tetramer Immunization and Selection Followed by CELLISA Screening to Generate Monoclonal Antibodies against the Mouse Cytomegalovirus m12 Immunoevasin

artículo científico publicado en 2020

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance

artículo científico publicado en 2002

The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment

artículo científico publicado en 2003

The 1.5 Å Crystal Structure of a Prokaryote Serpin

article

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis

artículo científico publicado en 2007

The 1.7 A crystal structure of Dronpa: a photoswitchable green fluorescent protein

artículo científico publicado en 2006

The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding

artículo científico publicado en 2006

The 2.0-A crystal structure of eqFP611, a far red fluorescent protein from the sea anemone Entacmaea quadricolor

artículo científico publicado en 2003

The 2.1A crystal structure of copGFP, a representative member of the copepod clade within the green fluorescent protein superfamily

artículo científico publicado en 2006

The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore

artículo científico publicado en 2005

The 2.2 A crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation

artículo científico publicado en 2003

The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain

artículo científico publicado en 2007

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

article

The Diverse Family of MR1-Restricted T Cells

The Diverse Family of MR1-Restricted T Cells

artículo científico publicado en 2018

The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule

artículo científico publicado en 2012

The Ly49 natural killer cell receptors: a versatile tool for viral self-discrimination

artículo científico

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

artículo científico publicado en 1999

The N terminus of the serpin, tengpin, functions to trap the metastable native state

artículo científico publicado en 2007

The Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound Peptide

artículo científico publicado en 2010

The Structure of the Bacterial Oxidoreductase Enzyme DsbA in Complex with a Peptide Reveals a Basis for Substrate Specificity in the Catalytic Cycle of DsbA Enzymes

artículo científico publicado en 2009

The Structure of the Cytomegalovirus-Encoded m04 Glycoprotein, a Prototypical Member of the m02 Family of Immunoevasins

artículo científico publicado en 2014

The burgeoning family of unconventional T cells

artículo científico publicado en 2015

The cellular redox environment alters antigen presentation

artículo científico publicado en 2014

The cryo-EM structure of the endocytic receptor DEC-205

scientific article published on 30 November 2020

The crystal structure of glucose dehydrogenase from Thermoplasma acidophilum

artículo científico publicado en 1994

The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis

artículo científico publicado en 2003

The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network

scientific article published on 01 February 2019

The fidelity, occasional promiscuity, and versatility of T cell receptor recognition

artículo científico publicado en 2008

The heterodimeric assembly of the CD94-NKG2 receptor family and implications for human leukocyte antigen-E recognition

artículo científico publicado en 2007

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition

artículo científico publicado en 2004

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix

artículo científico publicado en 2005

The identification and structure of the membrane-spanning domain of the Clostridium septicum alpha toxin

artículo científico publicado en 2004

The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation

artículo científico publicado en 2005

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

article

The impact of a large and frequent deletion in the human TCR β locus on antiviral immunity

artículo científico publicado en 2012

The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family

artículo científico publicado en 2011

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

artículo científico publicado en 2005

The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope

artículo científico publicado en 2014

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in Rheumatoid Arthritis

artículo científico publicado en 2018

The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1.

artículo científico publicado en 2016

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity.

artículo científico publicado en 2008

The molecular bases of δ/αβ T cell-mediated antigen recognition.

artículo científico publicado en 2014

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule

artículo científico publicado en 2017

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function

scientific article published on 13 May 2020

The molecular basis underpinning the potency and specificity of MAIT cell antigens

artículo científico publicado en 2020

The molecular mechanism of pneumolysin, a virulence factor from Streptococcus pneumoniae.

artículo científico publicado en 1998

The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins

artículo científico publicado en 2005

The peptide length specificity of some HLA class I alleles is very broad and includes peptides of up to 25 amino acids in length

article

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

artículo científico publicado en 2007

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

artículo científico publicado en 2004

The production, purification and crystallization of a pocilloporin pigment from a reef-forming coral

artículo científico publicado en 2003

The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt

artículo científico publicado en 2005

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

artículo científico publicado en 2002

The shaping of T cell receptor recognition by self-tolerance

artículo científico publicado en 2009

The structural bases of direct T-cell allorecognition: implications for T-cell-mediated transplant rejection

artículo científico publicado en 2011

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

artículo científico publicado en 2010

The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

artículo científico publicado en 2005

The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance

artículo científico publicado en 2004

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization

artículo científico publicado en 2002

The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

artículo científico publicado en 2015

The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution

artículo científico publicado en 1997

The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate

artículo científico publicado en 1997

The versatility of the αβ T-cell antigen receptor

scientific article published on 28 January 2014

Tissue specificity of cross-reactive allogeneic responses by EBV EBNA3A-specific memory T cells

artículo científico publicado en 2011

Toll-like receptors: structural pieces of a curve-shaped puzzle

artículo científico publicado en 2007

Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

artículo científico publicado en 2016

Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians

artículo científico publicado en 2015

Tracking the unfolding pathway of a multirepeat protein via tryptophan scanning: evidence of localized instability in the mitochondrial import receptor Tom70.

artículo científico publicado en 2006

Transplantation Immunology

scholarly article published 2013 in Methods in Molecular Biology

Tumors reveal their secrets to cytotoxic T cells

artículo científico publicado en 2006

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function

artículo científico publicado en 2006

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae.

artículo científico publicado en 1999

Understanding the complexity and malleability of T-cell recognition

artículo científico

Valine 10 May Act as a Driver for Product Release from the Active Site of Human Glutathione Transferase P1-1

artículo científico publicado en 2000

Variations on the GFP chromophore: A polypeptide fragmentation within the chromophore revealed in the 2.1-A crystal structure of a nonfluorescent chromoprotein from Anemonia sulcata

artículo científico publicado en 2004

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

artículo científico publicado en 2011

X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation

artículo científico publicado en 2006

αβ T Cell Receptors Come Out Swinging

αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands

artículo científico publicado en 2015

β-Amino acid-containing hybrid peptides—new opportunities in peptidomimetics