Lista de obras - Ana Denicola - Dominio Público Uruguay

2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents

artículo científico publicado en 2006

Acceleration of nitric oxide autoxidation and nitrosation by membranes.

artículo científico publicado en 2007

Acceleration of the autoxidation of nitric oxide by proteins

scientific article published on 30 January 2019

Antioxidant activity of uruguayan propolis. In vitro and cellular assays

artículo científico publicado en 2011

Antioxidant and diffusion properties of nitric oxide in low-density lipoprotein

artículo científico publicado en 2002

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds.

artículo científico publicado en 2005

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Structure-activity relationships. Part II.

artículo científico publicado en 2002

Catalysis of Peroxide Reduction by Fast Reacting Protein Thiols

artículo científico publicado en 2019

Commentary on "Using resonance synchronous spectroscopy to characterize the reactivity and electrophilicity of biologically relevant sulfane sulfur". Evidence that the methodology is inadequate because it only measures unspecific light scattering

scientific article published on 20 July 2019

Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: Role of the hydroxamic groups ⬇️

artículo científico publicado el 1 de julio de 1995

Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.

artículo científico publicado en 2004

Detection and quantification of nitric oxide-derived oxidants in biological systems

scientific article published on 12 August 2019

Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.

artículo científico publicado en 2018

Differential parameters between cytosolic 2-Cys peroxiredoxins, PRDX1 and PRDX2

artículo científico publicado en 2018

Diffusion and Transport of Reactive Species Across Cell Membranes

artículo científico publicado en 2019

Diffusion of nitric oxide and oxygen in lipoproteins and membranes studied by pyrene fluorescence quenching

scientific article published on 16 April 2018

Diffusion of nitric oxide into low density lipoprotein.

artículo científico publicado en 2001

Diffusion of peroxynitrite across erythrocyte membranes ⬇️

artículo científico publicado el 31 de marzo de 1998

Direct measurement of nitric oxide and oxygen partitioning into liposomes and low density lipoprotein

scientific article published on 04 January 2005

Distance-dependent diffusion-controlled reaction of •NO and O2•- at chemical equilibrium with ONOO-

scientific article published on 10 November 2010

EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes

artículo científico publicado en 2002

Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays

artículo científico

Extramitochondrial localization of NADH-fumarate reductase in trypanosomatids

artículo científico publicado en 2002

Factors affecting protein thiol reactivity and specificity in peroxide reduction

artículo científico publicado en 2011

Foreword to the Free Radical Biology and Medicine Special Issue on ¨Current fluorescence and chemiluminescence approaches in free radical and redox biology¨

artículo científico publicado en 2018

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

artículo científico publicado en 2004

Inactivation of cystathionine beta-synthase with peroxynitrite.

scientific article published on 03 September 2009

Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center

artículo científico publicado en 2013

Kinetic and stoichiometric constraints determine the pathway of H2O2 consumption by red blood cells

artículo científico publicado en 2018

Kinetics of the Reaction of Pyrogallol Red, a Polyphenolic Dye, with Nitrous Acid: Role of NO and NO2.

artículo científico publicado en 2015

Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation.

artículo científico publicado en 2010

Long-chain n-3 polyunsaturated fatty acid from fish oil modulates aortic nitric oxide and tocopherol status in the rat.

artículo científico

Membrane "lens" effect: focusing the formation of reactive nitrogen oxides from the *NO/O2 reaction

scientific article published on 28 March 2007

Mode of action of nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?

artículo científico publicado en 2010

N-acetylcysteine improves the quality of red blood cells stored for transfusion

artículo científico publicado en 2017

New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies

artículo científico publicado en 2006

New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies

artículo científico publicado en 2005

New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach

artículo científico publicado en 2018

Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.

artículo científico publicado en 2014

Nitrofurylsemicarbazone Rhenium and Ruthenium Complexes as Anti-trypanosomal Agents

scientific article published on 07 July 2006

Nitrogen dioxide solubility and permeation in lipid membranes ⬇️

artículo científico publicado el 15 de junio de 2011

Novel antiprotozoal products: imidazole and benzimidazole N-oxide derivatives and related compounds.

artículo científico publicado en 2004

Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets

scholarly article by Lucía Otero et al published 1 June 2006 in Journal of Medicinal Chemistry

Peroxiredoxins as preferential targets in H2O2-induced signaling

artículo científico publicado en 2013

Peroxynitrite and drug-dependent toxicity

artículo científico publicado en 2005

Peroxynitrite-Mediated Decarboxylation of Pyruvate to Both Carbon Dioxide and Carbon Dioxide Radical Anion ⬇️

artículo científico publicado el 1 de julio de 1997

Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione.

artículo científico publicado en 2008

Potential Modulation of Sirtuins by Oxidative Stress

artículo científico publicado en 2016

Protein tryptophan accessibility studied by fluorescence quenching

scholarly article by Matías Möller published in May 2002

Purification of a recombinant glutathione transferase from the causative agent of hydatidosis, Echinococcus granulosus

artículo científico publicado en 2015

Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

artículo científico publicado en 2019

Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals

artículo científico publicado en 2003

Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals

artículo científico publicado en 2004

Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

artículo científico publicado en 2010

Red blood cells in the metabolism of nitric oxide-derived peroxynitrite

artículo científico publicado en 2006

Sevoflurane anesthesia deteriorates pulmonary surfactant promoting alveolar collapse in male Sprague-Dawley rats

artículo científico publicado en 2014

Solubility and diffusion of oxygen in phospholipid membranes

artículo científico publicado en 2016

Solubility and permeation of hydrogen sulfide in lipid membranes.

artículo científico publicado en 2012

Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form

artículo científico publicado en 2015

Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives ⬇️

artículo científico publicado el 1 de febrero de 1998

The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

artículo científico publicado en 2008

The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity

artículo científico publicado en 2003

Tools to evaluate the conformation of protein products

artículo científico publicado en 2011

Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193

scientific article published on 16 July 2019

Use of diaminofluoresceins to detect and measure nitric oxide in low level generating human immune cells.

artículo científico publicado en 2008

Lista de obras de Ana Denicola

2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents

Acceleration of nitric oxide autoxidation and nitrosation by membranes.

Acceleration of the autoxidation of nitric oxide by proteins

Antioxidant activity of uruguayan propolis. In vitro and cellular assays

Antioxidant and diffusion properties of nitric oxide in low-density lipoprotein

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Part 3: Substituents-clustering methodology in the search for new active compounds.

Benzo[1,2-c]1,2,5-oxadiazole N-oxide derivatives as potential antitrypanosomal drugs. Structure-activity relationships. Part II.

Catalysis of Peroxide Reduction by Fast Reacting Protein Thiols

Commentary on "Using resonance synchronous spectroscopy to characterize the reactivity and electrophilicity of biologically relevant sulfane sulfur". Evidence that the methodology is inadequate because it only measures unspecific light scattering

Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: Role of the hydroxamic groups ⬇️

Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.

Detection and quantification of nitric oxide-derived oxidants in biological systems

Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.

Differential parameters between cytosolic 2-Cys peroxiredoxins, PRDX1 and PRDX2

Diffusion and Transport of Reactive Species Across Cell Membranes

Diffusion of nitric oxide and oxygen in lipoproteins and membranes studied by pyrene fluorescence quenching

Diffusion of nitric oxide into low density lipoprotein.

Diffusion of peroxynitrite across erythrocyte membranes ⬇️

Direct measurement of nitric oxide and oxygen partitioning into liposomes and low density lipoprotein

Distance-dependent diffusion-controlled reaction of •NO and O2•- at chemical equilibrium with ONOO-

EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes

Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays

Extramitochondrial localization of NADH-fumarate reductase in trypanosomatids

Factors affecting protein thiol reactivity and specificity in peroxide reduction

Foreword to the Free Radical Biology and Medicine Special Issue on ¨Current fluorescence and chemiluminescence approaches in free radical and redox biology¨

In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

Inactivation of cystathionine beta-synthase with peroxynitrite.

Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center

Kinetic and stoichiometric constraints determine the pathway of H2O2 consumption by red blood cells

Kinetics of the Reaction of Pyrogallol Red, a Polyphenolic Dye, with Nitrous Acid: Role of NO and NO2.

Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation.

Long-chain n-3 polyunsaturated fatty acid from fish oil modulates aortic nitric oxide and tocopherol status in the rat.

Membrane "lens" effect: focusing the formation of reactive nitrogen oxides from the *NO/O2 reaction

Mode of action of nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?

N-acetylcysteine improves the quality of red blood cells stored for transfusion

New potent 5-nitrofuryl derivatives as inhibitors of Trypanosoma cruzi growth. 3D-QSAR (CoMFA) studies

New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: quantitative structure-activity relationship studies

New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach

Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.

Nitrofurylsemicarbazone Rhenium and Ruthenium Complexes as Anti-trypanosomal Agents

Nitrogen dioxide solubility and permeation in lipid membranes ⬇️

Novel antiprotozoal products: imidazole and benzimidazole N-oxide derivatives and related compounds.

Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets

Peroxiredoxins as preferential targets in H2O2-induced signaling

Peroxynitrite and drug-dependent toxicity

Peroxynitrite-Mediated Decarboxylation of Pyruvate to Both Carbon Dioxide and Carbon Dioxide Radical Anion ⬇️

Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione.

Potential Modulation of Sirtuins by Oxidative Stress

Protein tryptophan accessibility studied by fluorescence quenching

Purification of a recombinant glutathione transferase from the causative agent of hydatidosis, Echinococcus granulosus

Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals

Reactions of desferrioxamine with peroxynitrite-derived carbonate and nitrogen dioxide radicals

Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest

Red blood cells in the metabolism of nitric oxide-derived peroxynitrite

Sevoflurane anesthesia deteriorates pulmonary surfactant promoting alveolar collapse in male Sprague-Dawley rats

Solubility and diffusion of oxygen in phospholipid membranes

Solubility and permeation of hydrogen sulfide in lipid membranes.

Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form

Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives ⬇️

The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity

Tools to evaluate the conformation of protein products

Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193

Use of diaminofluoresceins to detect and measure nitric oxide in low level generating human immune cells.